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Journal Articles

Deconstructing the Clonal Advantage and Clonal Stability of 5q- Candidate Genes in Del(5q) MDS on a Single Cell Level

Ursula S.A. Stalmann, MD, Fabio Ticconi, MSc, Ronghui Li, MSc, Aaron B. Wong, PhD, Glenn Cowley, PhD, David E. Root, PhD, Dirk Heckl, PhD, Inge Snoeren, MSc, Sergio Martinez, PhDMSc, Tim H Brümmendorf, MD, Andreas Schuppert, PhD, Ivan Costa, PhD, Benjamin L. Ebert, MD PhD, Rebekka K. Schneider, MD PhD

Blood (2019) 134 (Supplement_1): 559.

https://doi.org/10.1182/blood-2019-122588

Published: 2019

Journal Articles

Oncogenic Cooperation between EGR1 and BRD4 in Diffuse Large B Cell Lymphoma

Lixin Rui, PhD

Blood (2019) 134 (Supplement_1): 1508.

https://doi.org/10.1182/blood-2019-124839

Published: 2019

Journal Articles

Identification of Gene Regulatory Networks Governing Stemness Properties of Human HSC and LSC

Stanley W.K. Ng, Stephanie Zhi-Juan Xie, PhD, Elvin Wagenblast, PhD, Naoya Takayama, MD PhD, Liqing Jin, MD, Nathan Mbong, Alex Murison, Schoof E Erwin, Amanda Mitchell, PhD, Peter Van Galen, PhD, Mathieu Lupien, PhD, Mark D. Minden, MD PhD, Jean C.Y. Wang, MD PhD, Peter W. Zandstra, PhD, John E. Dick

Blood (2018) 132 (Supplement 1): 3832.

https://doi.org/10.1182/blood-2018-99-114314

Published: 2018

Journal Articles

hsa-mir183/EGR1 –mediated regulation of E2F1 is required for CML stem/progenitor cell survival

Francesca Pellicano, Laura Park, Lisa E. M. Hopcroft, Mansi M. Shah, Lorna Jackson, Mary T. Scott, Cassie J. Clarke, Amy Sinclair, Sheela A. Abraham, Alan Hair, G. Vignir Helgason, Mark Aspinall-O’Dea, Ravi Bhatia, Gustavo Leone, Kamil R. Kranc, Anthony D. Whetton, Tessa L. Holyoake

Blood (2018) 131 (14): 1532–1544.

https://doi.org/10.1182/blood-2017-05-783845

Published: 2018

Includes: Supplemental data

Journal Articles

Gfi1-Mediated Repression of C-Fos , Egr1 and Egr2 , and Inhibition of ERK1/2 Signaling Contribute to the Role of Gfi1 in Granulopoiesis

Yangyang Zhang, MD, Nan Hu, PhD, Fan Dong, MD PhD

Blood (2017) 130 (Supplement 1): 3765.

https://doi.org/10.1182/blood.V130.Suppl_1.3765.3765

Published: 2017

Journal Articles

Early Growth Response (EGR)-1 Is a Key Regulator of Human Primary Bone Marrow Stroma Cells with a Dual Role in Proliferation and Hematopoietic Stroma Support Function

Hongzhe Li, PhD, Roshanak Ghazanfari, PhD, Hooi Ching Lim, PhD, Jenny Hansson, PhD, Dimitra Zacharaki, Stefan Scheding, MD

Blood (2017) 130 (Supplement 1): 3777.

https://doi.org/10.1182/blood.V130.Suppl_1.3777.3777

Published: 2017

Journal Articles

Haploinsufficiency of Multiple Genes on Del(5q) Cooperate to Induce B Cell Abnormalities in Mice

Tanzir Ahmed, PhD, Tuoen Liu, MD PhD, Kilannin Krysiak, PhD, Matthew Ndonwi, PhD, Matthew J. Walter, MD

Blood (2017) 130 (Supplement 1): 2947.

https://doi.org/10.1182/blood.V130.Suppl_1.2947.2947

Published: 2017

Journal Articles

Early Growth Response (EGR)-1 Expression Regulates Colony Forming Capacity and Hematopoietic Support Function in Human Primary Bone Marrow Stromal Stem Cells

Hongzhe Li, PhD, Roshanak Ghazanfari, Dimitra Zacharaki, Hooi Ching Lim, PhD, Stefan Scheding, MD

Blood (2016) 128 (22): 3886.

https://doi.org/10.1182/blood.V128.22.3886.3886

Published: 2016

Journal Articles

4EBP1/c-MYC/PUMA and NF-κB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells

Seongseok Yun, Nicole D. Vincelette, Katherine L. B. Knorr, Luciana L. Almada, Paula A. Schneider, Kevin L. Peterson, Karen S. Flatten, Haiming Dai, Keith W. Pratz, Allan D. Hess, B. Douglas Smith, Judith E. Karp, Andrea E. Wahner Hendrickson, Martin E. Fernandez-Zapico, Scott H. Kaufmann

Blood (2016) 127 (22): 2711–2722.

https://doi.org/10.1182/blood-2015-02-629485

Published: 2016

Includes: Supplemental data

Journal Articles

Identification of Novel Mir-34a Targets in a c-Myc Murine Model

Jorge R. Contreras, BS, Tiffany M Tran, Jayanth Kumar Palanichamy, MDMBBS, David Casero, PhD, Dinesh S. Rao, MDPhD

Blood (2015) 126 (23): 4826.

https://doi.org/10.1182/blood.V126.23.4826.4826

Published: 2015

Journal Articles

Identification of Initiating Trunk Mutations and Distinct Molecular Subtypes: An Interim Analysis of the Mmrf Commpass Study

Blood (2015) 126 (23): 722.

https://doi.org/10.1182/blood.V126.23.722.722

Published: 2015

Journal Articles

CDK6 as a key regulator of hematopoietic and leukemic stem cell activation

Ruth Scheicher, Andrea Hoelbl-Kovacic, Florian Bellutti, Anca-Sarmiza Tigan, Michaela Prchal-Murphy, Gerwin Heller, Christine Schneckenleithner, María Salazar-Roa, Sabine Zöchbauer-Müller, Johannes Zuber, Marcos Malumbres, Karoline Kollmann, Veronika Sexl

Blood (2015) 125 (1): 90–101.

https://doi.org/10.1182/blood-2014-06-584417

Published: 2015

Includes: Supplemental data

Journal Articles

Elevated EGR2 Expression Provides a Potential Link Between Cell Cycle Arrest and Induced Differentiation in Myeloid Progenitor Cells

Joshua B. Bland, BS, Jose R. Peralta, BS, William T. Tse, MD PhD

Blood (2014) 124 (21): 2733.

https://doi.org/10.1182/blood.V124.21.2733.2733

Published: 2014

Journal Articles

Interim Analysis of the Mmrf Commpass Trial: Identification of Novel Rearrangements Potentially Associated with Disease Initiation and Progression

Blood (2014) 124 (21): 722.

https://doi.org/10.1182/blood.V124.21.722.722

Published: 2014

Journal Articles

Cell intrinsic and extrinsic factors synergize in mice with haploinsufficiency for Tp53, and two human del(5q) genes, Egr1 and Apc

Angela Stoddart, Jianghong Wang, Anthony A. Fernald, Theodore Karrison, John Anastasi, Michelle M. Le Beau

Blood (2014) 123 (2): 228–238.

https://doi.org/10.1182/blood-2013-05-506568

Published: 2014

Includes: Supplemental data

Journal Articles

Retroviral Insertional Mutagenesis In Egr1 +/- mice, Haploinsufficient For a Human Del(5q) Myeloid Leukemia Gene, Develop Myeloid Neoplasms With Proviral Insertions In Genes Syntenic To Human 5q

Angela Stoddart, PhD, Anthony Fernald, Rachel Joy Bergerson, PhD, Jianghong Wang, M.D., Megan E. McNerney, MD, PhD, Theodore Karrison, Ph.D., John Anastasi, MD, Elizabeth Bartom, Ph.D., Aaron G. Sarver, Ph.D., Zhijian Qian, PhD, Linda Wolff, PhD, David A. Largaespada, PhD, Michelle M. le Beau, PhD

Blood (2013) 122 (21): 1275.

https://doi.org/10.1182/blood.V122.21.1275.1275

Published: 2013

Journal Articles

Profilin 1 Is Essential for Retention and Metabolism of Hematopoietic Stem Cells in Bone Marrow

Junke Zheng, Chengcheng Zhang, Ph.D

Blood (2012) 120 (21): 1224.

https://doi.org/10.1182/blood.V120.21.1224.1224

Published: 2012

Journal Articles

Reduced C/EBPα Expression Favors Monopoiesis Over Granulopoiesis

Alan D. Friedman, M.D., Ou Ma, Ph.D., SunHwa Hong, Ph.D.

Blood (2012) 120 (21): 1230.

https://doi.org/10.1182/blood.V120.21.1230.1230

Published: 2012

Journal Articles

The Type of Genetic Abnormalities Causing Loss of 5q Varies Between MDS and AML and Is Associated with Worse Prognosis in MDS

Claudia Haferlach, MD, Vera Grossmann, MSc, Alexander Kohlmann, PhD, Susanne Schnittger, PhD, Wolfgang Kern, MD, Torsten Haferlach, MD

Blood (2012) 120 (21): 697.

https://doi.org/10.1182/blood.V120.21.697.697

Published: 2012

Journal Articles

CD34+ FISH As a New Method for Molecular-Cytogenetic Diagnostic From Peripheral Blood in MDS: Update of the Multicenter German Prospective Diagnostic Study

Blood (2012) 120 (21): 3816.

https://doi.org/10.1182/blood.V120.21.3816.3816

Published: 2012

NARROW

Deconstructing the Clonal Advantage and Clonal Stability of 5q- Candidate Genes in Del(5q) MDS on a Single Cell Level

Oncogenic Cooperation between EGR1 and BRD4 in Diffuse Large B Cell Lymphoma

Identification of Gene Regulatory Networks Governing Stemness Properties of Human HSC and LSC

hsa-mir183/EGR1 –mediated regulation of E2F1 is required for CML stem/progenitor cell survival

Gfi1-Mediated Repression of C-Fos , Egr1 and Egr2 , and Inhibition of ERK1/2 Signaling Contribute to the Role of Gfi1 in Granulopoiesis

Early Growth Response (EGR)-1 Is a Key Regulator of Human Primary Bone Marrow Stroma Cells with a Dual Role in Proliferation and Hematopoietic Stroma Support Function

Haploinsufficiency of Multiple Genes on Del(5q) Cooperate to Induce B Cell Abnormalities in Mice

Early Growth Response (EGR)-1 Expression Regulates Colony Forming Capacity and Hematopoietic Support Function in Human Primary Bone Marrow Stromal Stem Cells

4EBP1/c-MYC/PUMA and NF-κB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells

Identification of Novel Mir-34a Targets in a c-Myc Murine Model

Identification of Initiating Trunk Mutations and Distinct Molecular Subtypes: An Interim Analysis of the Mmrf Commpass Study

CDK6 as a key regulator of hematopoietic and leukemic stem cell activation

Elevated EGR2 Expression Provides a Potential Link Between Cell Cycle Arrest and Induced Differentiation in Myeloid Progenitor Cells

Interim Analysis of the Mmrf Commpass Trial: Identification of Novel Rearrangements Potentially Associated with Disease Initiation and Progression

Cell intrinsic and extrinsic factors synergize in mice with haploinsufficiency for Tp53, and two human del(5q) genes, Egr1 and Apc

Retroviral Insertional Mutagenesis In Egr1 +/- mice, Haploinsufficient For a Human Del(5q) Myeloid Leukemia Gene, Develop Myeloid Neoplasms With Proviral Insertions In Genes Syntenic To Human 5q

Profilin 1 Is Essential for Retention and Metabolism of Hematopoietic Stem Cells in Bone Marrow

Reduced C/EBPα Expression Favors Monopoiesis Over Granulopoiesis

The Type of Genetic Abnormalities Causing Loss of 5q Varies Between MDS and AML and Is Associated with Worse Prognosis in MDS

CD34+ FISH As a New Method for Molecular-Cytogenetic Diagnostic From Peripheral Blood in MDS: Update of the Multicenter German Prospective Diagnostic Study

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American Society of Hematology

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American Society of Hematology

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