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Journal Articles

Effects of Andexanet Alfa on Thrombin Generation in Bleeding Associated with Factor Xa Inhibitors

Michiel Coppens, MD, Lizhen Xu, PhD, Roisin Bavalia, MD, Saskia Middeldorp, MD PhD, Peter Verhamme, MD PhD, John W. Eikelboom, MBBS, MSc, FRACP, FRCPA, Mark Crowther, MD, Genmin Lu, Patrick Yue, MD, Pamela B. Conley, PhD, Stuart J. Connolly, MD MSc, FRCPC

Blood (2019) 134 (Supplement_1): 711.

https://doi.org/10.1182/blood-2019-124596

Published: 2019

Journal Articles

Characterization of Recombinant β2GPI Using Hydrogen-Deuterium Exchange and X-Ray Crystallography

Ravi Kumar Alluri, PhD, Nicholas Arce, Philip Klenotic, Chih Chia Su, PhD, Suman Kundu, MBA, Edward Yu, PhD, Renhao Li, PhD, Keith R McCrae, MD

Blood (2019) 134 (Supplement_1): 1105.

https://doi.org/10.1182/blood-2019-131386

Published: 2019

Journal Articles

Reversal of Apixaban Anticoagulation with Reduced Doses of Andexanet Alfa in a Porcine Polytrauma Model

Oliver Grottke, MD PhD MPH, Necib Akman, MD, Till Braunschweig, MD, Pamela B. Conley, PhD, Rolf Rossaint, MD

Blood (2018) 132 (Supplement 1): 2456.

https://doi.org/10.1182/blood-2018-99-114426

Published: 2018

Journal Articles

Hydrogen-Deuterium Exchange Plus Mass Spectrometry (HX-MS) Reveals a Novel Mechanism Underlying the pH-Dependent Regulation of ADAMTS13 Activity

Catherine B. Zander, PhD, Vikram G. Pillai, PhD, Leland Mayne, PhD, S. Walter Englander, PhD, X. Long Zheng, MD, PhD

Blood (2017) 130 (Supplement 1): 238.

https://doi.org/10.1182/blood.V130.Suppl_1.238.238

Published: 2017

Journal Articles

Molecular Design and Characterization of a Novel, Vwf Independent Coagulation Factor VIII (LAFATE)

Eui-Cheol Jo, PhD, Injae Oh, MS, Seung-hoon Lee, PhD, Mee Sook Oh, MS, Jae Hwan Ryu, MS, Yong Jae Kim, PhD, Jin-hyeon Park, MS, So Ra Kim, MS, Myung Eun Jung, PhD

Blood (2017) 130 (Supplement 1): 2342.

https://doi.org/10.1182/blood.V130.Suppl_1.2342.2342

Published: 2017

Journal Articles

Mapping the Masked Region of the A1 Domain in Full-Length VWF

Wei Deng, PhD, Ernest T. Parker, BA, John S. Lollar, MD, Renhao Li, PhD

Blood (2017) 130 (Supplement 1): 3599.

https://doi.org/10.1182/blood.V130.Suppl_1.3599.3599

Published: 2017

Journal Articles

Calcium-Induced Conformational Changes in EF hands and Autoinhibitory Linker Region are Critical for Catalytic Activity of CalDAG-GEFI Towards the Small GTPase Rap1

Aaron Cook, Wei Deng, PhD, Renhao Li, PhD, John Sondek, PhD, Wolfgang Bergmeier, PhD

Blood (2017) 130 (Supplement 1): 3614.

https://doi.org/10.1182/blood.V130.Suppl_1.3614.3614

Published: 2017

Journal Articles

Analysis of a Naturally Occurring PAR4 Variant By Hydrogen/Deuterium Exchange Reveals Its Structural Rearrangement upon Activation By Thrombin and the Molecular Basis for Altered Reactivity

Xu Han, BS, MS, Lukas Hofmann, PhD, Maria de la Fuente, BS, Tivadar Orban, PhD, Nathan Alexander, PhD, Krzysztof Palczewski, PhD, Marvin T Nieman, PhD

Blood (2017) 130 (Supplement 1): 453.

https://doi.org/10.1182/blood.V130.Suppl_1.453.453

Published: 2017

Journal Articles

Reactive Oxygen Species and Metabolic Gene Expression Profiling Further Differentiate CXCR4/CD5 Fractions in Chronic Lymphocytic Leukemia

Eric Sturgill, BA, Xiao J. Yan, MDPhD, Florencia Palacios, PhD, Kanti Rai, MD, Jacqueline C. Barrientos, MD, Steven L. Allen, MD, Jonathan E. Kolitz, MD, Nicholas Chiorazzi, MD

Blood (2017) 130 (Supplement 1): 4287.

https://doi.org/10.1182/blood.V130.Suppl_1.4287.4287

Published: 2017

Journal Articles

G-CSF-induced sympathetic tone provokes fever and primes antimobilizing functions of neutrophils via PGE 2

Yuko Kawano, Chie Fukui, Masakazu Shinohara, Kanako Wakahashi, Shinichi Ishii, Tomohide Suzuki, Mari Sato, Noboru Asada, Hiroki Kawano, Kentaro Minagawa, Akiko Sada, Tomoyuki Furuyashiki, Satoshi Uematsu, Shizuo Akira, Toshimitsu Uede, Shuh Narumiya, Toshimitsu Matsui, Yoshio Katayama

Blood (2017) 129 (5): 587–597.

https://doi.org/10.1182/blood-2016-07-725754

Published: 2017

Includes: Supplemental data

Journal Articles

Effects of Packed Red Cell Transfusion on Blood Glucose Concentrations in Beta Thalassemia Major (BTM) Ashort Presentations of Personal Experience

Mohamed A. Yassin, MBBS, MSc, CABM, FACP, Ashraf Tawfiq Soliman, MD PhD

Blood (2016) 128 (22): 4839.

https://doi.org/10.1182/blood.V128.22.4839.4839

Published: 2016

Journal Articles

A Short N-Terminal Fragment in Front of the A1 Domain of Von Willebrand Factor Prevents the A1 from Binding the Platelet By Masking a Region Clustered By Type 2B VWD Mutations

Wei Deng, PhD, Yingchun Wang, PhD, Pete Lollar, MD, Renhao Li, PhD

Blood (2016) 128 (22): 553.

https://doi.org/10.1182/blood.V128.22.553.553

Published: 2016

Journal Articles

Structural Basis for the Procofactor to Cofactor Transition in Human Factor V

Shekhar Kumar, PhD, Wei Deng, PhD, Steven Stayrook, PhD, Renhao Li, PhD, Rodney M. Camire, PhD, Sriram Krishnaswamy, PhD

Blood (2016) 128 (22): 253.

https://doi.org/10.1182/blood.V128.22.253.253

Published: 2016

Journal Articles

Hydrogen Exchange Mass Spectrometry Reveals Allosteric Interactions Between the Distal and the Proximal Domains of Human ADAMTS13

Catherine B. Zander, PhD, Leland Mayne, PhD, S. Walter Englander, PhD, X. Long Zheng, MD, PhD

Blood (2016) 128 (22): 2535.

https://doi.org/10.1182/blood.V128.22.2535.2535

Published: 2016

Journal Articles

High-affinity, noninhibitory pathogenic C1 domain antibodies are present in patients with hemophilia A and inhibitors

Glaivy Batsuli, Wei Deng, John F. Healey, Ernest T. Parker, W. Hunter Baldwin, Courtney Cox, Brenda Nguyen, Joerg Kahle, Christoph Königs, Renhao Li, Pete Lollar, Shannon L. Meeks

Blood (2016) 128 (16): 2055–2067.

https://doi.org/10.1182/blood-2016-02-701805

Published: 2016

Includes: Supplemental data

Journal Articles

Human neutrophil kinetics: modeling of stable isotope labeling data supports short blood neutrophil half-lives

Julio Lahoz-Beneytez, Marjet Elemans, Yan Zhang, Raya Ahmed, Arafa Salam, Michael Block, Christoph Niederalt, Becca Asquith, Derek Macallan

Blood (2016) 127 (26): 3431–3438.

https://doi.org/10.1182/blood-2016-03-700336

Published: 2016

Includes: Supplemental data

Journal Articles

In-Vivo Labelling Studies in Patients with Chronic Lymphocytic Leukemia Studies Demonstrate the Existence of Apparently Distinct Subpopulations That Differ in Phenotype and Proliferative Capacity

Kirsty Cuthill, FRCPath,MBBS,MRCP, Yan Zhang, PhD, Andrea Buggins, PhD MBA, Eve Coulter, PhD, Piers E. Patten, BSc, MRCP, MRCPath, PhD, Derek Macallan, PhD MBBS, Stephen Devereux, FRCP, FRCPath, PhD

Blood (2015) 126 (23): 615.

https://doi.org/10.1182/blood.V126.23.615.615

Published: 2015

Journal Articles

Identification of Active Coagulation Factor IX Variants with Insertion or Fusion of Unstructured Polypeptide Xten

Zhiqian Lucy Liu, PhD, Arjan van der Flier, PhD, Sara Bardan, Sheng Ding, Volker Schellenberger, PhD, John Kulman, PhD, Robert Peters, PhD

Blood (2015) 126 (23): 2280.

https://doi.org/10.1182/blood.V126.23.2280.2280

Published: 2015

Journal Articles

FVIII-VWF dos-à-dos

Sriram Krishnaswamy

Blood (2015) 126 (8): 923–924.

https://doi.org/10.1182/blood-2015-06-652073

Published: 2015

Journal Articles

Mapping the interaction between factor VIII and von Willebrand factor by electron microscopy and mass spectrometry

Po-Lin Chiu, George M. Bou-Assaf, Ekta Seth Chhabra, Melissa G. Chambers, Robert T. Peters, John D. Kulman, Thomas Walz

Blood (2015) 126 (8): 935–938.

https://doi.org/10.1182/blood-2015-04-641688

Published: 2015

Includes: Multimedia, Supplemental data

NARROW

Effects of Andexanet Alfa on Thrombin Generation in Bleeding Associated with Factor Xa Inhibitors

Characterization of Recombinant β2GPI Using Hydrogen-Deuterium Exchange and X-Ray Crystallography

Reversal of Apixaban Anticoagulation with Reduced Doses of Andexanet Alfa in a Porcine Polytrauma Model

Hydrogen-Deuterium Exchange Plus Mass Spectrometry (HX-MS) Reveals a Novel Mechanism Underlying the pH-Dependent Regulation of ADAMTS13 Activity

Molecular Design and Characterization of a Novel, Vwf Independent Coagulation Factor VIII (LAFATE)

Mapping the Masked Region of the A1 Domain in Full-Length VWF

Calcium-Induced Conformational Changes in EF hands and Autoinhibitory Linker Region are Critical for Catalytic Activity of CalDAG-GEFI Towards the Small GTPase Rap1

Analysis of a Naturally Occurring PAR4 Variant By Hydrogen/Deuterium Exchange Reveals Its Structural Rearrangement upon Activation By Thrombin and the Molecular Basis for Altered Reactivity

Reactive Oxygen Species and Metabolic Gene Expression Profiling Further Differentiate CXCR4/CD5 Fractions in Chronic Lymphocytic Leukemia

G-CSF-induced sympathetic tone provokes fever and primes antimobilizing functions of neutrophils via PGE 2

Effects of Packed Red Cell Transfusion on Blood Glucose Concentrations in Beta Thalassemia Major (BTM) Ashort Presentations of Personal Experience

A Short N-Terminal Fragment in Front of the A1 Domain of Von Willebrand Factor Prevents the A1 from Binding the Platelet By Masking a Region Clustered By Type 2B VWD Mutations

Structural Basis for the Procofactor to Cofactor Transition in Human Factor V

Hydrogen Exchange Mass Spectrometry Reveals Allosteric Interactions Between the Distal and the Proximal Domains of Human ADAMTS13

High-affinity, noninhibitory pathogenic C1 domain antibodies are present in patients with hemophilia A and inhibitors

Human neutrophil kinetics: modeling of stable isotope labeling data supports short blood neutrophil half-lives

In-Vivo Labelling Studies in Patients with Chronic Lymphocytic Leukemia Studies Demonstrate the Existence of Apparently Distinct Subpopulations That Differ in Phenotype and Proliferative Capacity

Identification of Active Coagulation Factor IX Variants with Insertion or Fusion of Unstructured Polypeptide Xten

FVIII-VWF dos-à-dos

Mapping the interaction between factor VIII and von Willebrand factor by electron microscopy and mass spectrometry

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American Society of Hematology

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ASH Publications

American Society of Hematology

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