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Journal Articles

Cytochromes P450 and Glutathione S-Transferases Polymorphisms: Can They Predict Efficacy of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia?

Samina N. Mukry, PhD, Aneeta Shahni, BS, Uzma Zaidi, FCPS, Tahir S. Shamsi, MBBS,FRCPath

Blood (2019) 134 (Supplement_1): 5920.

https://doi.org/10.1182/blood-2019-129655

Published: 2019

Journal Articles

Aryl Hydrocarbon Receptor (AHR) Antagonism As a Transformative, Dual-Mechanism Novel Therapy for Multiple Myeloma

Taylor Gonzalez, Evan C Catton, Ashley E. Rosko, MD, Yvonne Efebera, MD, Maria Chaudhry, MD, Francesca Cottini, MD, Bethany L Mundy-Bosse, PhD, Tiffany Hughes, BS, PhD, Don M. Benson, Jr., MD PhD

Blood (2018) 132 (Supplement 1): 1933.

https://doi.org/10.1182/blood-2018-99-117465

Published: 2018

Journal Articles

Association of APEX1 and NUDT15 Polymorphisms with Mercaptopurine-Related Neutropenia in Pediatric Acute Lymphoblastic Leukemia

Hyery Kim, MD, Heewon Seo, Yoomi Park, ByungJoo Min, Myung-Eui Seo, Kyung Duk Park, MD, Hee Young Shin, MD, Jae Won Yoo, MD, Sung Han Kang, MD, Kyung Nam Koh, MD, Jong Jin Seo, MD, Ho Joon Im, MD, Ju Han Kim, MD, Hyoung Jin Kang, MD

Blood (2017) 130 (Supplement 1): 1320.

https://doi.org/10.1182/blood.V130.Suppl_1.1320.1320

Published: 2017

Journal Articles

Aryl Hydrocarbon Receptor Antagonism Promotes Hematoendothelial Development from Human Pluripotent Stem Cells

Mathew G. Angelos, BS, Anna Kim, Dan S. Kaufman, MD, PhD

Blood (2015) 126 (23): 3585.

https://doi.org/10.1182/blood.V126.23.3585.3585

Published: 2015

Journal Articles

Aryl Hydrocarbon Receptor (AhR) Pathway Directly Controls Hematopoietic Proliferation in Chronic Myeloid Leukemia (CML) and Its Inhibition Allows Massive Expansion of Leukemic Progenitors and Stem Cells

Melanie Gentil, MD, Patricia Hugues, Gladys Telliam, Ivan Sloma, PharmD,PhD, Seda Baykal, Jerome Artus, PhD, Agnes Guerci, MD, Hyacinthe Johnson Ansa, Adlen Foudi, PhD, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD PhD

Blood (2015) 126 (23): 4013.

https://doi.org/10.1182/blood.V126.23.4013.4013

Published: 2015

Journal Articles

A Pharmacogenetic Study of the NCIC CTG Clinical Trial My.10: Single Nucleotide Polymorphisms, Prognosis, and Predicting Benefit from IMiD® Compound Maintenance Therapy Following Autologous Stem Cell Transplant for Multiple Myeloma

Ming Han, BSc., Alli Murugesan, MSc, PhD, Nizar J Bahlis, MD, Kevin Song, Darrell White, MD MSc, FRCPC, FACP, Christine Chen, MD, Matthew D. Seftel, MBChB, FRCP(C), MRCP, Kang Howsen-Jan, MD, Donna Reece, Keith Stewart, MD, Yagang Xie, MD PhD FCCMG, Annette E Hay, MB ChB, Lois Shepherd, MD, Bingshu E Chen, PhD, Marina Djurfeldt, MSc., Tony Reiman, MD

Blood (2015) 126 (23): 2960.

https://doi.org/10.1182/blood.V126.23.2960.2960

Published: 2015

Journal Articles

Tryptophan Catabolites Directly Modulate the Immunosuppressive Effects of MSCs Via Activation of the Endogenous Aryl Hydrocarbon Receptor

Christopher N Lewis, AB, Raghavan Chinnadurai, PhD, Jacques Galipeau, MD

Blood (2014) 124 (21): 1593.

https://doi.org/10.1182/blood.V124.21.1593.1593

Published: 2014

Journal Articles

Characterizing Rare Variants in Drug Metabolism Genes in Refractory Pediatric High-Risk Pre-B ALL

Andrew Hughes, Joseph Giacalone, Todd E Druley, MD, PhD

Blood (2012) 120 (21): 879.

https://doi.org/10.1182/blood.V120.21.879.879

Published: 2012

Journal Articles

Dll1/Notch Interaction Contributes to a Decreased Sensitivity of Myeloma Cells to Bortezomib

Dehui Xu, Jingsong Hu, Elke De Bruyne, PhD, Eline Menu, PhD, Rik Schots, MD, Karin Vanderkerken, PhD, Els Van Valckenborgh, PhD

Blood (2012) 120 (21): 1840.

https://doi.org/10.1182/blood.V120.21.1840.1840

Published: 2012

Journal Articles

Clinical Significance of Polymorphisms During Hepatopoietic Stem Cell Transplantation.

Jae-Sook Ahn, Hee Nam Kim, Nan Young Kim, Yu– Li, Il-Kwon Lee, Yeo-Kyeoung Kim, Soo-Young Bae, Deok-Hwan Yang, Je-Jung Lee, Hyeoung Joon Kim, MD, PhD

Blood (2010) 116 (21): 3497.

https://doi.org/10.1182/blood.V116.21.3497.3497

Published: 2010

Journal Articles

Genetic Associations with Bortezomib Mediated Neuropathy in Multiple Myeloma.

Sophie L Corthals, David C Johnson, Yvonne de Knegt, Hartmut Goldschmidt, Henk Lokhorst, Stéphane Minvielle, Florence Magrangeas, Jean-Luc Harousseau, Brian G M Durie, Brian G Van Ness, Gareth J Morgan, Pieter Sonneveld, Hervé Avet Loiseau

Blood (2009) 114 (22): 1794.

https://doi.org/10.1182/blood.V114.22.1794.1794

Published: 2009

Journal Articles

Genetic Susceptibility to Therapy-Related Leukemia (t-MDS/AML) After Hodgkin Lymphoma (HL) or Non-Hodgkin Lymphoma (NHL).

Yan Ding, Can-Lan Sun, Liton Francisco, Melanie Sabado, Liang Li, Brian Hahn, Garrett Larson, Stephen J. Forman, Ravi Bhatia, Smita Bhatia

Blood (2009) 114 (22): 199.

https://doi.org/10.1182/blood.V114.22.199.199

Published: 2009

Journal Articles

Genetic Variation in ADME Genes Is Associated with Thalidomide Related Peripheral Neuropathy in Multiple Myeloma Patients.

David C Johnson, Christine Ramos, Alex J. Szubert, Walter M Gregory, J. Anthony Child, Faith E Davies, MD, Brian GM Durie, MD, Brian G. Van Ness, PhD, Gareth J Morgan, MD, PhD

Blood (2008) 112 (11): 1675.

https://doi.org/10.1182/blood.V112.11.1675.1675

Published: 2008

Journal Articles

Prognostic Significance of NQO1 Polymorphism and GST-M1 Deletion in De Novo Acute Myeloid Leukemia

Yeo-Kyeoung Kim, Hee-Je Kim, Woo-Sung Min, Jong- Ho Won, Deog-Yeon Jo, Moo-Rim Park, Hee-Nam Kim, Il-Kwon Lee, Jae-Sook Ahn, Deok-Hwan Yang, Je-Jung Lee, Hyeoung-Joon Kim

Blood (2008) 112 (11): 4846.

https://doi.org/10.1182/blood.V112.11.4846.4846

Published: 2008

Journal Articles

Multidrug Resistance Gene (MDR1) Polymorphisms May Serve as Predictors of Resistance to Imatinib in Chronic Phase Chronic Myeloid Leukemia Patients.

Simona Soverini, Sabrina Angelini, Eleonora Turrini, Alessandra Gnani, Sabrina Colarossi, Giovanni Perini, Ilaria Iacobucci, Patrizia Hrelia, Giorgio Cantelli Forti, Daniela Cilloni, Giuseppe Saglio, Fabrizio Pane, Michele Baccarani, Thea Kalebic, Giovanni Martinelli

Blood (2007) 110 (11): 1946.

https://doi.org/10.1182/blood.V110.11.1946.1946

Published: 2007

Journal Articles

Genetic Polymorphisms Correlated with Outcome in Multiple Myeloma Patients Receiving High Dose Melphalan.

Charles Dumontet, MD, PhD, Stefano Landi, PhD, Tony Reiman, MD, PhD, Adriana Plesa, MD, Ilaria Bellini, PhD, Roberto Barale, PhD, Linda M. Pilarski, MD, Sean Tavtigian, PhD, Troy Perry, BsC, Federica Gemignani, PhD

Blood (2007) 110 (11): 4746.

https://doi.org/10.1182/blood.V110.11.4746.4746

Published: 2007

Journal Articles

High Risk of Acute Myeloid Leukemia in Individuals with NAD(P)H:Quinone Oxidoreductase 1 ( NQO1 ) and Cytochrome P450 A1 ( CYP1A1 ) Gene Defects.

Gabriela G. Yamaguti, Gustavo J. Lourenco, M.Sc., Fernando F. Costa, Ph.D., Carmen S.P. Lima, Ph.D.

Blood (2007) 110 (11): 2843.

https://doi.org/10.1182/blood.V110.11.2843.2843

Published: 2007

Journal Articles

Association between Drug-Metabolizing Enzymes Polymorphisms and Diffuse Large B-Cell Lymphoma Risk in the Middle Eastern Population.

Abdul K. Siraj, BSc, Rong Bu, MD/PHD, Maha Al-Rasheed, BSc, Muna Ibrahim, DVM, Prashant Bavi, MBBS, Jehad Abubaker, PhD, Naif Al-Jomah, BSc, Walid Mourad, MD, Fouad Al-Dayel, MD, Adnan Ezzat, MD, Hassan El-Solh, MD, Shahab Uddin, PhD, Khawla Al-Kuraya, MD/FCAP

Blood (2006) 108 (11): 2043.

https://doi.org/10.1182/blood.V108.11.2043.2043

Published: 2006

Journal Articles

Assessment of the Aryl Hydrocarbon Receptor Gene as a Therapeutic Target in Childhood T-Lineage Acute Lymphoblastic Leukemia.

Marrit Meier, MSc, Monique L. den Boer, PhD, Mathilde J.C. Broekhuis, BSc, Ronald W. Stam, MSc, Elisabeth R. van Wering, PhD, Gritta E. Janka-Schaub, PhD, Rob Pieters, MD, PhD

Blood (2005) 106 (11): 536.

https://doi.org/10.1182/blood.V106.11.536.536

Published: 2005

Journal Articles

Polymorphisms in Xenobiotic Genes and Risk of Developing Diffuse Large B-Cell Lymphoma in Saudi Population.

Abdul K. Siraj, BSc, Rong Bu, MD, PhD, Mona Ibrahim, DVM, MSc, Maha Al-Rasheed, BSc, Jehad Abubaker, PhD, Naif Al-Jumaah, BSc, Khawla Al-Kuraya, MD, FCAP

Blood (2005) 106 (11): 4424.

https://doi.org/10.1182/blood.V106.11.4424.4424

Published: 2005

NARROW

Cytochromes P450 and Glutathione S-Transferases Polymorphisms: Can They Predict Efficacy of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia?

Aryl Hydrocarbon Receptor (AHR) Antagonism As a Transformative, Dual-Mechanism Novel Therapy for Multiple Myeloma

Association of APEX1 and NUDT15 Polymorphisms with Mercaptopurine-Related Neutropenia in Pediatric Acute Lymphoblastic Leukemia

Aryl Hydrocarbon Receptor Antagonism Promotes Hematoendothelial Development from Human Pluripotent Stem Cells

Aryl Hydrocarbon Receptor (AhR) Pathway Directly Controls Hematopoietic Proliferation in Chronic Myeloid Leukemia (CML) and Its Inhibition Allows Massive Expansion of Leukemic Progenitors and Stem Cells

A Pharmacogenetic Study of the NCIC CTG Clinical Trial My.10: Single Nucleotide Polymorphisms, Prognosis, and Predicting Benefit from IMiD® Compound Maintenance Therapy Following Autologous Stem Cell Transplant for Multiple Myeloma

Tryptophan Catabolites Directly Modulate the Immunosuppressive Effects of MSCs Via Activation of the Endogenous Aryl Hydrocarbon Receptor

Characterizing Rare Variants in Drug Metabolism Genes in Refractory Pediatric High-Risk Pre-B ALL

Dll1/Notch Interaction Contributes to a Decreased Sensitivity of Myeloma Cells to Bortezomib

Clinical Significance of Polymorphisms During Hepatopoietic Stem Cell Transplantation.

Genetic Associations with Bortezomib Mediated Neuropathy in Multiple Myeloma.

Genetic Susceptibility to Therapy-Related Leukemia (t-MDS/AML) After Hodgkin Lymphoma (HL) or Non-Hodgkin Lymphoma (NHL).

Genetic Variation in ADME Genes Is Associated with Thalidomide Related Peripheral Neuropathy in Multiple Myeloma Patients.

Prognostic Significance of NQO1 Polymorphism and GST-M1 Deletion in De Novo Acute Myeloid Leukemia

Multidrug Resistance Gene (MDR1) Polymorphisms May Serve as Predictors of Resistance to Imatinib in Chronic Phase Chronic Myeloid Leukemia Patients.

Genetic Polymorphisms Correlated with Outcome in Multiple Myeloma Patients Receiving High Dose Melphalan.

High Risk of Acute Myeloid Leukemia in Individuals with NAD(P)H:Quinone Oxidoreductase 1 ( NQO1 ) and Cytochrome P450 A1 ( CYP1A1 ) Gene Defects.

Association between Drug-Metabolizing Enzymes Polymorphisms and Diffuse Large B-Cell Lymphoma Risk in the Middle Eastern Population.

Assessment of the Aryl Hydrocarbon Receptor Gene as a Therapeutic Target in Childhood T-Lineage Acute Lymphoblastic Leukemia.

Polymorphisms in Xenobiotic Genes and Risk of Developing Diffuse Large B-Cell Lymphoma in Saudi Population.

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American Society of Hematology

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American Society of Hematology

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