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Journal Articles

Safe Use of Hydroxyurea in Sickle Cell Disease Patients Hospitalized for Painful Vaso-Occlusive Episodes: Results of the Randomized, Open-Label Helps Study

Nicola Conran, PhD, Kleber Yotsumoto Fertrin, MD PhD, Claudia de Alvarenga Maximo, MD, Thais Oliveira, B.Sc., Clarisse Lobo, MD PhD, Fernando Ferreira Costa, MD PhD

Blood (2019) 134 (Supplement_1): 2303.

https://doi.org/10.1182/blood-2019-130106

Published: 2019

Journal Articles

Common Myeloid Progenitors As Biomarkers of Hbf Response to Hydroxyurea in Sickle Cell Disease

Caterina P. Minniti, MD, Seda S. Tolu, MD, Kai Wang, PhD, Zi Yan, Andrew Crouch, Gracy Sebastian, NP, Mark Chaitowitz, MD, Evan Schwechter, MD, Joan Uehlinger, MD, Deepa Manwani, MD, Eric Fornari, MD, Eric E. Bouhassira, PhD

Blood (2019) 134 (Supplement_1): 4827.

https://doi.org/10.1182/blood-2019-131466

Published: 2019

Journal Articles

Clinical Evidence Against the Continuum of Low-Primed Uncommitted Hematopoietic and Progenitor Cells (CLOUD-HSPC) Concept for Hematopoiesis

Ramon Mohanlal, PhD MD, Douglas W. Blayney, MD, Lan Huang, PhD

Blood (2019) 134 (Supplement_1): 4860.

https://doi.org/10.1182/blood-2019-128563

Published: 2019

Journal Articles

Clinical Evidence of Granulocyte-Monocyte Progenitor (GMP) Stem Cell Involvement in Plinabulin's Mechanism of Action (MoA) for the Prevention of Docetaxel (Doc) Chemotherapy (Chemo)-Induced Neutropenia (CIN)

Douglas W. Blayney, MD, Lan Huang, PhD, Ramon Mohanlal, PhD MD

Blood (2019) 134 (Supplement_1): 4861.

https://doi.org/10.1182/blood-2019-127227

Published: 2019

Journal Articles

Identifying the Leukemia Stem Cell Niche Mediating Drug Resistance in Flt3-ITD Acute Myeloid Leukemia

Nick R Anderson, BS, Hui Li, BS, Mason W Harris, Shaowei Qiu, MD, Andrew J Paterson, PhD, Ravi Bhatia, MD

Blood (2019) 134 (Supplement_1): 909.

https://doi.org/10.1182/blood-2019-124379

Published: 2019

Journal Articles

Manufacturing Scale-up and Preclinical Development of ET-01, Autologous CD34 + Cells with the BCL11A Erythroid Enhancer Edited By CRISPR/Cas9, for Patients with β-Thalassemia Major

Riguo Fang, PhD, Pengfei Yuan, PhD, Lingling Yu, Bachelor, Huihui Yang, Master, Jie Liu, Master, Jia Shi, PhD, Yongjian Zhang, PhD, Wei Zhang, PhD, Yiding Zhao, PhD, Zhiyong Peng, MD, Chunfu Li, MD, Yun Li, MD, Dong Wei, PhD

Blood (2019) 134 (Supplement_1): 965.

https://doi.org/10.1182/blood-2019-126499

Published: 2019

Journal Articles

The Multidrug Transporter MRP4/ABCC4 Involved in the Leukemia Clinical Course Specifies the Novel PEL Human Blood Group System

Blood (2019) 134 (Supplement_1): 715.

https://doi.org/10.1182/blood-2019-124082

Published: 2019

Journal Articles

Excessive R-Loops Trigger an Inflammatory Cascade Leading to Aberrant Hematopoietic Stem and Progenitor Cell Expansion

Joshua Weinreb, MSc, Varun Gupta, Teresa V. Bowman, PhD

Blood (2019) 134 (Supplement_1): 772.

https://doi.org/10.1182/blood-2019-124888

Published: 2019

Journal Articles

Long-Term Hydroxyurea Use Is Associated with Lower Levels of Hematopoietic Stem and Progenitor Cells in Patients with Sickle Cell Disease

Seda S. Tolu, MD, Kai Wang, PhD, Zi Yan, Andrew Crouch, Gracy Sebastian, NP, Mark Chaitowitz, MD, Eric Fornari, MD, Evan Schwechter, MD, Joan Uehlinger, MD, Deepa Manwani, MD, Caterina P. Minniti, MD, Eric E. Bouhassira, PhD

Blood (2019) 134 (Supplement_1): 985.

https://doi.org/10.1182/blood-2019-131648

Published: 2019

Journal Articles

Loss of Dnmt3a Dysregulates Hematopoietic Homeostasis and Myeloid Skewing Via the PI3Kinase Pathway: PI3Kα/β Inhibition Corrects Extramedullary Hematopoiesis and Myeloid Skewing Due to Loss of Dnmt3a

Lakshmi Reddy Palam, PhD, Baskar Ramdas, PhD, Katelyn Pickerell, Reuben Kapur, PhD

Blood (2019) 134 (Supplement_1): 723.

https://doi.org/10.1182/blood-2019-131036

Published: 2019

Journal Articles

Automated Manufacture of Matched Donor-Derived Allogeneic CD19 CAR T-Cells for Relapsed/Refractory B-ALL Following Allogeneic Stem Cell Transplantation: Toxicity, Efficacy and the Important Role of Lymphodepletion

Blood (2019) 134 (Supplement_1): 776.

https://doi.org/10.1182/blood-2019-129640

Published: 2019

Journal Articles

Transcriptomic and Metabolomic Profiling Identifies Calcium-Dependent Signaling Mechanisms As a Novel and Exploitable Target to Overcome Anti-CD20 Resistance in Non-Hodgkin Lymphoma (NHL)

Ravi Dashnamoorthy, PhD, Saheli Sarkar, PhD, Afshin Beheshti, PhD, Maisarah Mokhtar, B.S, Tali Konry, PhD, Michael Levin, PhD, Andrew M. Evens, DO, MSc

Blood (2019) 134 (Supplement_1): 1511.

https://doi.org/10.1182/blood-2019-126539

Published: 2019

Journal Articles

Functional Complementation between β-Catenin and Hoxa9 Sustains HSC Self-Renewal in a Prmt1-Dependent Manner

Jennifer Lynch, PhD, Clemence Virely, PhD, Priscilla Lau, PhD, Huacheng Luo, PhD, Suming Huang, PhD, Eric Chi Wai So, PhD

Blood (2019) 134 (Supplement_1): 449.

https://doi.org/10.1182/blood-2019-131052

Published: 2019

Journal Articles

Preclinical Evaluation for Engraftment of Gene-Edited CD34+ Cells with a Sickle Cell Disease Mutation in a Rhesus Transplantation Model

Naoya Uchida, MD, Linhong Li, PhD, Tina Nassehi, Morgan Yapundich, Jackson Gamer, Claire Drysdale, Juan J. Haro-Mora, PhD, Selami Demirci, PhD, Aylin Bonifacino, MS, Allen Krouse, Nathaniel S. Linde, Cornell Allen, MS, Suk See De Ravin, MD, PhD, Robert E. Donahue, VMD, Harry L. Malech, MD, Madhusudan Peshwa, PhD, John F. Tisdale, MD

Blood (2019) 134 (Supplement_1): 609.

https://doi.org/10.1182/blood-2019-122727

Published: 2019

Journal Articles

Spatial Mapping of Myelopoiesis Reveals the Bone Marrow Niche for Monocyte Dendritic Cell Progenitors

Jizhou Zhang, Qingqing Wu, PhD, Courtney Johnson, BS, André Olsson, MS, PhD, Anastasiya Slaughter, BA, Margot Lindsay May, BS, Benjamin Weinhaus, BS, Emily Bowers, PhD, James Douglas Engel, PhD, Jean X. Jiang, PhD, Sherry L. Abboud-Werner, PhD, Nathan Salomonis, PhD, H. Leighton Grimes, PhD, Daniel Lucas-Alcaraz, PhD

Blood (2019) 134 (Supplement_1): 528.

https://doi.org/10.1182/blood-2019-128809

Published: 2019

Journal Articles

Autism-Associated Chromatin Remodeler CHD8 Governs the Survival and Differentiation of Hematopoietic Stem/Progenitor Cells

Zhaowei Tu, PhD, Chen Wang, MSc, Chuntao Zhao, PhD, Lei Huang, PhD, Nathan Salomonis, PhD, Richard Q Lu, PhD, Yi Zheng, PhD

Blood (2019) 134 (Supplement_1): 1191.

https://doi.org/10.1182/blood-2019-127313

Published: 2019

Journal Articles

Cellular and Molecular Architecture of Hematopoietic Stem Cells and Progenitors in Genetic Models of Bone Marrow Failure

Stephanie C. Heidemann, MD, Brian Bursic, Sasan Zandi, MD PhD, Hongbing Li, PhD, Robert J Klaassen, MD FRCPC, Sharon Abish, MD, Meera Rayar, Vicky R. Breakey, BSc,MDFRCPC, Houtan Moshiri, PhD, Santhosh Dhanraj, PhD, Richard de Borja, PhD, Adam Shlien, PhD, John E. Dick, PhD, Yigal Dror, MDFRCPC, Sagi Abelson, PhD

Blood (2019) 134 (Supplement_1): 1223.

https://doi.org/10.1182/blood-2019-130534

Published: 2019

Journal Articles

Critical Requirement of U2AF1 in the Maintenance and Function of Hematopoietic Stem Cells

Avik Dutta, PhD, Yue Yang, PhD, Bao Le, Golam Mohi, PhD

Blood (2019) 134 (Supplement_1): 1195.

https://doi.org/10.1182/blood-2019-132007

Published: 2019

Journal Articles

In Vitro Functionality of hiPSC Derived PLT+: The Utility of Microfluidic Assays in Determining Potency

Marcus Lehmann, PhD, Annie K Burton, Savannah G Szemethy, Jorge Valdez, PhD, Jonathan N. Thon, PhD

Blood (2019) 134 (Supplement_1): 1168.

https://doi.org/10.1182/blood-2019-131896

Published: 2019

Journal Articles

Collection and Processing of Bone Marrow at 3% Oxygen Significantly Alters the Manifestation of Aged Mouse Hematopoietic Stem Cell Phenotype

Maegan L. Capitano, PhD, Scott Cooper, M.S., Bin Guo, PhD, Xinxin Huang, PhD, Carol Sampson, MS, Safa Mohamad, Edward F. Srour, PhD, Christie M. Orschell, PhD, Hal E. Broxmeyer, PhD

Blood (2019) 134 (Supplement_1): 1202.

https://doi.org/10.1182/blood-2019-128642

Published: 2019

NARROW

Safe Use of Hydroxyurea in Sickle Cell Disease Patients Hospitalized for Painful Vaso-Occlusive Episodes: Results of the Randomized, Open-Label Helps Study

Common Myeloid Progenitors As Biomarkers of Hbf Response to Hydroxyurea in Sickle Cell Disease

Clinical Evidence Against the Continuum of Low-Primed Uncommitted Hematopoietic and Progenitor Cells (CLOUD-HSPC) Concept for Hematopoiesis

Clinical Evidence of Granulocyte-Monocyte Progenitor (GMP) Stem Cell Involvement in Plinabulin's Mechanism of Action (MoA) for the Prevention of Docetaxel (Doc) Chemotherapy (Chemo)-Induced Neutropenia (CIN)

Identifying the Leukemia Stem Cell Niche Mediating Drug Resistance in Flt3-ITD Acute Myeloid Leukemia

Manufacturing Scale-up and Preclinical Development of ET-01, Autologous CD34 + Cells with the BCL11A Erythroid Enhancer Edited By CRISPR/Cas9, for Patients with β-Thalassemia Major

The Multidrug Transporter MRP4/ABCC4 Involved in the Leukemia Clinical Course Specifies the Novel PEL Human Blood Group System

Excessive R-Loops Trigger an Inflammatory Cascade Leading to Aberrant Hematopoietic Stem and Progenitor Cell Expansion

Long-Term Hydroxyurea Use Is Associated with Lower Levels of Hematopoietic Stem and Progenitor Cells in Patients with Sickle Cell Disease

Loss of Dnmt3a Dysregulates Hematopoietic Homeostasis and Myeloid Skewing Via the PI3Kinase Pathway: PI3Kα/β Inhibition Corrects Extramedullary Hematopoiesis and Myeloid Skewing Due to Loss of Dnmt3a

Automated Manufacture of Matched Donor-Derived Allogeneic CD19 CAR T-Cells for Relapsed/Refractory B-ALL Following Allogeneic Stem Cell Transplantation: Toxicity, Efficacy and the Important Role of Lymphodepletion

Transcriptomic and Metabolomic Profiling Identifies Calcium-Dependent Signaling Mechanisms As a Novel and Exploitable Target to Overcome Anti-CD20 Resistance in Non-Hodgkin Lymphoma (NHL)

Functional Complementation between β-Catenin and Hoxa9 Sustains HSC Self-Renewal in a Prmt1-Dependent Manner

Preclinical Evaluation for Engraftment of Gene-Edited CD34+ Cells with a Sickle Cell Disease Mutation in a Rhesus Transplantation Model

Spatial Mapping of Myelopoiesis Reveals the Bone Marrow Niche for Monocyte Dendritic Cell Progenitors

Autism-Associated Chromatin Remodeler CHD8 Governs the Survival and Differentiation of Hematopoietic Stem/Progenitor Cells

Cellular and Molecular Architecture of Hematopoietic Stem Cells and Progenitors in Genetic Models of Bone Marrow Failure

Critical Requirement of U2AF1 in the Maintenance and Function of Hematopoietic Stem Cells

In Vitro Functionality of hiPSC Derived PLT+: The Utility of Microfluidic Assays in Determining Potency

Collection and Processing of Bone Marrow at 3% Oxygen Significantly Alters the Manifestation of Aged Mouse Hematopoietic Stem Cell Phenotype

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American Society of Hematology

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ASH Publications

American Society of Hematology

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