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Journal Articles

Cell cycle control in Richter transformation

Christian P. Pallasch

Blood (2021) 138 (12): 1005–1007.

https://doi.org/10.1182/blood.2021011648

Published: 2021

Journal Articles

Preclinical Activity of the MPS1 Inhibitor S81694 in Acute Lymphoblastic Leukemia (ALL)

Anna Kaci, PhD, Emilie Adiceam, Melanie Dupont, Marine Garrido, Jeannig Berrou, Hanane Djamai, Andre Baruchel, Mike Burbridge, Claude Gardin, Herve Dombret, MD PhD, Thorsten Braun, MD

Blood (2019) 134 (Supplement_1): 2631.

https://doi.org/10.1182/blood-2019-125641

Published: 2019

Journal Articles

Novel ZBP1-IRF3 Dependency in Multiple Myeloma Mediated By IRF3-Driven Regulation of Cell Cycle Genes

Kanagaraju Ponnusamy, Maria-Myrsini Tzioni, MS, Murshida Begum, MS, Mark E Robinson, Valentina S Caputo, Alexia Katsarou, Nikolaos Trasanidis, Xiaolin Xiao, Ioannis V. Kostopoulos, Deena Iskander, MD, Irene Roberts, Pritesh Trivedi, MSc, Holger W Auner, MD PhD, Kikkeri Naresh, MD, Aristeidis Chaidos, Anastasios Karadimitris

Blood (2019) 134 (Supplement_1): 2521.

https://doi.org/10.1182/blood-2019-125768

Published: 2019

Journal Articles

Autism-Associated Chromatin Remodeler CHD8 Governs the Survival and Differentiation of Hematopoietic Stem/Progenitor Cells

Zhaowei Tu, PhD, Chen Wang, MSc, Chuntao Zhao, PhD, Lei Huang, PhD, Nathan Salomonis, PhD, Richard Q Lu, PhD, Yi Zheng, PhD

Blood (2019) 134 (Supplement_1): 1191.

https://doi.org/10.1182/blood-2019-127313

Published: 2019

Journal Articles

GATA2 -Dependent Developmental and Regenerative Networks

Alexandra Soukup, PhD, Kirby D Johnson, PhD, Daniel J Conn, PhD, Evgenia Shishkova, PhD, Koichi Ricardo Katsumura, MD PhD, Peng Liu, PhD, Erik A. Ranheim, MD PhD, Katherine R. Calvo, MD PhD, Amy P. Hsu, Steven M. Holland, MD, Joshua J Coon, PhD, Sunduz Keles, PhD, Emery H Bresnick, PhD

Blood (2019) 134 (Supplement_1): 1182.

https://doi.org/10.1182/blood-2019-126875

Published: 2019

Journal Articles

Identification of Novel Combination Therapies Active in BCL2 Inhibitor-Resistant Patient-Derived AML Models

Courtney L Andersen, PhD, Amanda L Christie, MS, Alan Rosen, MS, Kim Maratea, DVM, PhD, Maureen Hattersley, Jon Travers, PhD, Justin Cidado, PhD, Sai Pulukuri, PhD, Jamal Saeh, PhD, Edwin Clark, PhD, Corinne Reimer, PhD, Jerome Mettetal, PhD

Blood (2019) 134 (Supplement_1): 1273.

https://doi.org/10.1182/blood-2019-129475

Published: 2019

Journal Articles

RASA3 Is Essential for Early Mammalian Hematopoiesis and Modulates ERK Signaling in Terminal Erythropoiesis

Elena C. Brindley, BS, Raymond F. Robledo, PhD, Steven L. Ciciotte, MS, Joel H. Graber, PhD, Yue Zhao, Emily Hartman, BS, Julien Papoin, MS, Lionel Blanc, PhD, Luanne L. Peters, PhD

Blood (2019) 134 (Supplement_1): 3505.

https://doi.org/10.1182/blood-2019-130328

Published: 2019

Journal Articles

Higher Vertebrate Specific Gene Ribonuclease Inhibitor ( RNH1 ) Is Essential for Adult Hematopoietic Stem Cell Function and Cell Cycle Regulation

Nicola Daniele Andina, MD PhD, Mayuresh Sarangdhar, PhD, Aubry Tardivel, Giuseppe Bombaci, Mahmoud Hallal, BSc, MSc, Irene Keller, PhD, Ramanjaneyulu Allam, PhD MSc, BSc

Blood (2019) 134 (Supplement_1): 273.

https://doi.org/10.1182/blood-2019-128647

Published: 2019

Journal Articles

Dexamethasone Accelerates the Transition of Human BFU-E to CFU-E and Enhances CFU-E Proliferation through Cell Cycle Regulation

Ryan Ashley, BS, MS, Hongxia Yan, MS, Brian Dulmovits, BA, MS, Nan Wang, PhD, Julien Papoin, MS, Jeffrey M Lipton, MD PhD, Mohandas Narla, DSc, Anupama Narla, MD, Lionel Blanc, PhD

Blood (2018) 132 (Supplement 1): 3620.

https://doi.org/10.1182/blood-2018-99-116596

Published: 2018

Journal Articles

CARM1 Inhibition: Evaluation of Response and Efficacy in Acute Myeloid Leukemia

Adnan K Mookhtiar, BS, Sarah Greenblatt, PhD, Na Man, PhD, Daniel Karl, PhD, Vasileios Stathias, PhD, Stephan Schurer, PhD, Stephen D. Nimer, MD

Blood (2018) 132 (Supplement 1): 2719.

https://doi.org/10.1182/blood-2018-99-114981

Published: 2018

Journal Articles

Analysis of Sequential Patient Samples from the Mmrf Commpass Study Identifies a High Risk Progression Phenotype

Sheri Skerget, PhD, Daniel Penaherrera, BSc, Jessica Aldrich, Sara Nasser, PhD, Austin Christofferson, BSc, Christophe Legendre, Martin Boateng, BS, Lori Cuyugan, Jonathan Adkins, Erica Tassone, Jennifer Yesil, MS, Daniel Auclair, PhD, Winnie Liang, PhD, Sagar Lonial, MD, Jonathan J Keats, PhD

Blood (2018) 132 (Supplement 1): 111.

https://doi.org/10.1182/blood-2018-99-118617

Published: 2018

Journal Articles

Long-Term Interactions with Bone Marrow Stromal Cells Alter the Molecular Dependencies of Myeloma Cells: Insights from Genomewide CRISPR-Based Functional Genomic Screens

Sara Gandolfi, MD, Olga Dashevsky, PhD, Ricardo De Matos Simoes, PhD, Geoffrey Matthews, PhD, Ryosuke Shirasaki, MD PhD, Michal Sheffer, PhD, Constantine S. Mitsiades, MD PhD

Blood (2017) 130 (Supplement 1): 3028.

https://doi.org/10.1182/blood.V130.Suppl_1.3028.3028

Published: 2017

Journal Articles

CT7001, a Novel Orally Bio-Available CDK7 Inhibitor, Is Highly Active in in-Vitro and in-Vivo Models of AML

Kristopher Clark, PhD, Edward Ainscow, PhD, Adam Peall, Stuart Thomson, PhD, Andrew Leishman, PhD, Sullivan Elaine, PhD, Simak Ali, PhD, Raoul Coombes, MD, Anthony Barrett, PhD, Ash Kumar Bahl, PhD

Blood (2017) 130 (Supplement 1): 2645.

https://doi.org/10.1182/blood.V130.Suppl_1.2645.2645

Published: 2017

Journal Articles

FOXtrotting with PUMILIOs

Arefeh Rouhi, Florian Kuchenbauer

Blood (2017) 129 (18): 2459–2460.

https://doi.org/10.1182/blood-2017-03-771469

Published: 2017

Journal Articles

Inhibition of the Epigenetic Modifier EZH2 Upregulates Cell Cycle Control Genes to Inhibit Myeloma Cell Growth and Overcome High-Risk Disease Features

Charlotte Pawlyn, MB BChir, Michael Bright, PhD, Amy Buros, PhD, Caleb K. Stein, MS, Zoe Walters, PhD, Lauren Aronson, PhD, Fabio Mirabella, PhD, Martin F Kaiser, MD, John R Jones, MD, Brian A Walker, PhD, Graham H Jackson, MD PhD, Paul Clarke, PhD, Leif Bergsagel, MD, Paul Workman, PhD, Marta Chesi, PhD, Gareth J Morgan, MD PhD, Faith E Davies, MD

Blood (2016) 128 (22): 3289.

https://doi.org/10.1182/blood.V128.22.3289.3289

Published: 2016

Journal Articles

Ferritinophagy and Cell Cycle Control

Francesca Carlomagno, MD PhD

Blood (2016) 128 (22): SCI-20.

https://doi.org/10.1182/blood.V128.22.SCI-20.SCI-20

Published: 2016

Journal Articles

Phosphoproteomic Landscaping Unveils Constitutive cKIT Activation in Human Erythroblasts from Polycythemia Vera (PV) Patients

Lilian Varricchio, PhD, Giulia Federici, PhD, Francesca Masiello, MS, Fabrizio Martelli, PhD, Mario Falchi, PhD, Orietta Picconi, Gabriella Girelli, MD, Agostino Tafuri, MD, Emanuel Petricoin III, PhD, Ann Zeuner, PhD, Anna Rita Migliaccio, PhD

Blood (2016) 128 (22): 399.

https://doi.org/10.1182/blood.V128.22.399.399

Published: 2016

Journal Articles

Subset-Specific Recurrence of Mutations and Identification of Functional Modules Provides New Clues about the Pathogenesis of Large Granular Lymphocyte Leukemia

Alessandro Coppe, BSc, PhD, Emma I Andersson, MSc, Andrea Binatti, BSc, Vanessa R Gasparini, Sabrina Bortoluzzi, Michael J. Clemente, M.S., Marco Herling, MD PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP, Satu Mustjoki, MD PhD, Stefania Bortoluzzi, BSc, PhD

Blood (2016) 128 (22): 4117.

https://doi.org/10.1182/blood.V128.22.4117.4117

Published: 2016

Journal Articles

TRAF6 Is Essential for Maintaining Hematopoietic Stem Cell Homeostasis

Jing Fang, MD PhD, Lyndsey Bolanos, BSc, Juana Serrano-Lopez, PhD, Susanne Christie, Jose A Cancelas, MD PhD, Daniel T Starczynowski, PhD

Blood (2016) 128 (22): 568.

https://doi.org/10.1182/blood.V128.22.568.568

Published: 2016

Journal Articles

Mapping Microenvironment-Mediated Signaling Dependency of Targeted Inhibitors: A Mechanism-Based Approach of Selecting Effective Therapy Targeting Drug Resistant AML

Zhihong Zeng, MD, Wenbin Liu, PhD, Twee Tsao, MS, Yihua Qiu, MD, Ismael Samudio, PhD, Keith Baggerly, PhD, Steven M. Kornblau, MD, Hagop M Kantarjian, MD, Michael Andreeff, MD PhD, Marina Konopleva, MD PhD

Blood (2015) 126 (23): 1398.

https://doi.org/10.1182/blood.V126.23.1398.1398

Published: 2015

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Cell cycle control in Richter transformation

Preclinical Activity of the MPS1 Inhibitor S81694 in Acute Lymphoblastic Leukemia (ALL)

Novel ZBP1-IRF3 Dependency in Multiple Myeloma Mediated By IRF3-Driven Regulation of Cell Cycle Genes

Autism-Associated Chromatin Remodeler CHD8 Governs the Survival and Differentiation of Hematopoietic Stem/Progenitor Cells

GATA2 -Dependent Developmental and Regenerative Networks

Identification of Novel Combination Therapies Active in BCL2 Inhibitor-Resistant Patient-Derived AML Models

RASA3 Is Essential for Early Mammalian Hematopoiesis and Modulates ERK Signaling in Terminal Erythropoiesis

Higher Vertebrate Specific Gene Ribonuclease Inhibitor ( RNH1 ) Is Essential for Adult Hematopoietic Stem Cell Function and Cell Cycle Regulation

Dexamethasone Accelerates the Transition of Human BFU-E to CFU-E and Enhances CFU-E Proliferation through Cell Cycle Regulation

CARM1 Inhibition: Evaluation of Response and Efficacy in Acute Myeloid Leukemia

Analysis of Sequential Patient Samples from the Mmrf Commpass Study Identifies a High Risk Progression Phenotype

Long-Term Interactions with Bone Marrow Stromal Cells Alter the Molecular Dependencies of Myeloma Cells: Insights from Genomewide CRISPR-Based Functional Genomic Screens

CT7001, a Novel Orally Bio-Available CDK7 Inhibitor, Is Highly Active in in-Vitro and in-Vivo Models of AML

FOXtrotting with PUMILIOs

Inhibition of the Epigenetic Modifier EZH2 Upregulates Cell Cycle Control Genes to Inhibit Myeloma Cell Growth and Overcome High-Risk Disease Features

Ferritinophagy and Cell Cycle Control

Phosphoproteomic Landscaping Unveils Constitutive cKIT Activation in Human Erythroblasts from Polycythemia Vera (PV) Patients

Subset-Specific Recurrence of Mutations and Identification of Functional Modules Provides New Clues about the Pathogenesis of Large Granular Lymphocyte Leukemia

TRAF6 Is Essential for Maintaining Hematopoietic Stem Cell Homeostasis

Mapping Microenvironment-Mediated Signaling Dependency of Targeted Inhibitors: A Mechanism-Based Approach of Selecting Effective Therapy Targeting Drug Resistant AML

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