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Journal Articles

FXII inhibition: multipronged benefits

Helen Philippou

Blood (2021) 138 (2): 107–109.

https://doi.org/10.1182/blood.2021011032

Published: 2021

Journal Articles

Protease activity in single-chain prekallikrein

Ivan Ivanov, Ingrid M. Verhamme, Mao-fu Sun, Bassem Mohammed, Qiufang Cheng, Anton Matafonov, S. Kent Dickeson, Kusumam Joseph, Allen P. Kaplan, David Gailani

Blood (2020) 135 (8): 558–567.

https://doi.org/10.1182/blood.2019002224

Published: 2020

Includes: Supplemental data

Journal Articles

High Molecular Weight Kininogen but Not Factor XII Deficiency Attenuates Acetaminophen-Induced Liver Injury in Mice

Michael Wayne Henderson, MSc, Erica Sparkenbaugh, PhD BS, Denis Noubouossie, MD PhD, Reiner Mailer, Thomas Renne, MD PhD, Keith R McCrae, MD, Nigel S. Key, MBChB, FRCP, Rafal Pawlinski, PhD

Blood (2019) 134 (Supplement_1): 3621.

https://doi.org/10.1182/blood-2019-127206

Published: 2019

Journal Articles

Mitigation of Vascular Permeability Using Bradykinin Receptor Antagonist and Anti-Fibrinolytic Agent in Rats with Polytrauma and Hemorrhagic Shock

Xiaowu Wu, MD MSc, Daniel N. Darlington, PhD, Josue Garciamarcano, Bin Liu, BS, Jeffrey D Keesee, BS, James Bynum, PhD, Andrew P. Cap, MD PhD

Blood (2019) 134 (Supplement_1): 2345.

https://doi.org/10.1182/blood-2019-130278

Published: 2019

Journal Articles

Prevention of Bleeding-Induced Vascular Abnormalities in the Hemophilic Mouse Joint By Increasing TAFI Levels or Inhibiting uPA Activity

Tine Wyseure, PhD, Niels Behrendt, Annette von Drygalski, MD PharmD, Laurent O Mosnier

Blood (2019) 134 (Supplement_1): 158.

https://doi.org/10.1182/blood-2019-128723

Published: 2019

Journal Articles

Design and characterization of α1-antitrypsin variants for treatment of contact system–driven thromboinflammation

Steven de Maat, Wariya Sanrattana, Reiner K. Mailer, Naomi M. J. Parr, Martin Hessing, Robert M. Koetsier, Joost C. M. Meijers, Gerard Pasterkamp, Thomas Renné, Coen Maas

Blood (2019) 134 (19): 1658–1669.

https://doi.org/10.1182/blood.2019000481

Published: 2019

Includes: Supplemental data

Journal Articles

A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain

Ivan Ivanov, Anton Matafonov, Mao-fu Sun, Bassem M. Mohammed, Qiufang Cheng, S. Kent Dickeson, Suman Kundu, Ingrid M. Verhamme, Andras Gruber, Keith McCrae, David Gailani

Blood (2019) 133 (10): 1152–1163.

https://doi.org/10.1182/blood-2018-06-860270

Published: 2019

Includes: Supplemental data

Journal Articles

Heavy chain of FXII: not an innocent bystander!

Helen Philippou

Blood (2019) 133 (10): 1008–1009.

https://doi.org/10.1182/blood-2019-01-895110

Published: 2019

Journal Articles

High Molecular Weight Kininogen Contributes to End-Organ Damage and Mortality in a Mouse Model of Sickle Cell Disease

Erica Sparkenbaugh, PhD BS, Kathryn Wilson, BS, Malgorzata Kasztan, PhD, David M. Pollock, PhD, Keith R. McCrae, MD, Rafal Pawlinski, PhD

Blood (2018) 132 (Supplement 1): 268.

https://doi.org/10.1182/blood-2018-99-116526

Published: 2018

Journal Articles

Coagulation factor XII in thrombosis and inflammation

Coen Maas, Thomas Renné

Blood (2018) 131 (17): 1903–1909.

https://doi.org/10.1182/blood-2017-04-569111

Published: 2018

Journal Articles

High Molecular Weight Kininogen Alters the Tumor Microenvironment and Reduces Tumor Stem Cell Content

Meenal Shukla, James Hale, PhD, Justin Lathia, PhD, Keith McCrae, MD

Blood (2017) 130 (Supplement 1): 2340.

https://doi.org/10.1182/blood.V130.Suppl_1.2340.2340

Published: 2017

Journal Articles

Impact of the Coagulation System on the Pathogenesis of Alzheimer's Disease

Sidney Strickland, PhD

Blood (2017) 130 (Supplement 1): SCI-3.

https://doi.org/10.1182/blood.V130.Suppl_1.SCI-3.SCI-3

Published: 2017

Journal Articles

FXIIa Differentially Regulates Thrombin Generation during Steady State and Vaso-Occlusive Crisis in Sickle Cell Mice

Erica M Sparkenbaugh, PhD, Camille Faes, PhD, Denis Noubouossie, MD PhD, Daniel K. Kirchhofer, PhD, András Gruber, MD, Nigel S. Key, MB, ChB, Rafal Pawlinski, PhD

Blood (2016) 128 (22): 162.

https://doi.org/10.1182/blood.V128.22.162.162

Published: 2016

Journal Articles

Regulation of the Tumor Microenvironment By High Molecular Weight Kininogen

Meenal Shukla, PhD, Venkaiah Betapudi, PhD, Ravi Kumar Alluri, PhD, Sergei Merkulov, PhD, James Hale, PhD, Justin Lathia, PhD, Keith R. McCrae, MD

Blood (2016) 128 (22): 1394.

https://doi.org/10.1182/blood.V128.22.1394.1394

Published: 2016

Journal Articles

Defective TAFI Activation in Hemophilia Exacerbates Vascular Remodeling in Hemophilic Arthropathy

Tine L Wyseure, PhD, Esther J Cooke, PhD, Paul J Declerck, PhD, Joost CM Meijers, PhD, Annette von Drygalski, MD PharmD, Laurent O Mosnier, PhD

Blood (2016) 128 (22): 82.

https://doi.org/10.1182/blood.V128.22.82.82

Published: 2016

Journal Articles

Hyperfibrinolysis increases blood–brain barrier permeability by a plasmin- and bradykinin-dependent mechanism

Oscar A. Marcos-Contreras, Sara Martinez de Lizarrondo, Isabelle Bardou, Cyrille Orset, Mathilde Pruvost, Antoine Anfray, Yvann Frigout, Yannick Hommet, Laurent Lebouvier, Joan Montaner, Denis Vivien, Maxime Gauberti

Blood (2016) 128 (20): 2423–2434.

https://doi.org/10.1182/blood-2016-03-705384

Published: 2016

Includes: Supplemental data

Journal Articles

Discovery and Characterization of a Highly Specific Antibody Inhibitor of Factor XIIa, and the Subsequent Generation of a Factor XIIa/Plasma Kallikrein Bispecific Antibody

Blood (2015) 126 (23): 2268.

https://doi.org/10.1182/blood.V126.23.2268.2268

Published: 2015

Journal Articles

High Prevalence of Marginal ZONE Lymphoma Among Patients with Acquired C1- Inhibtor Deficiency

Roberto Castelli, Prof, Davide Rossi, MD PhD, Arquati Massimo, Suffritti Chiara, Andrea Zanichelli, Wu Maddalena, Cicardi Marco, Prof

Blood (2015) 126 (23): 1444.

https://doi.org/10.1182/blood.V126.23.1444.1444

Published: 2015

Journal Articles

Basic Mechanisms of Arterial and Venous Thrombosis

Thomas Renné, MD PhD

Blood (2014) 124 (21): SCI-1.

https://doi.org/10.1182/blood.V124.21.SCI-1.SCI-1

Published: 2014

Journal Articles

Bradykinin Receptors Regulate Proliferation, Migration and Tube Formation of Endothelial Progenitor Cells

Yi Wu, Nadia Backdash, Robert W. Colman

Blood (2014) 124 (21): 4176.

https://doi.org/10.1182/blood.V124.21.4176.4176

Published: 2014

NARROW

FXII inhibition: multipronged benefits

Protease activity in single-chain prekallikrein

High Molecular Weight Kininogen but Not Factor XII Deficiency Attenuates Acetaminophen-Induced Liver Injury in Mice

Mitigation of Vascular Permeability Using Bradykinin Receptor Antagonist and Anti-Fibrinolytic Agent in Rats with Polytrauma and Hemorrhagic Shock

Prevention of Bleeding-Induced Vascular Abnormalities in the Hemophilic Mouse Joint By Increasing TAFI Levels or Inhibiting uPA Activity

Design and characterization of α1-antitrypsin variants for treatment of contact system–driven thromboinflammation

A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain

Heavy chain of FXII: not an innocent bystander!

High Molecular Weight Kininogen Contributes to End-Organ Damage and Mortality in a Mouse Model of Sickle Cell Disease

Coagulation factor XII in thrombosis and inflammation

High Molecular Weight Kininogen Alters the Tumor Microenvironment and Reduces Tumor Stem Cell Content

Impact of the Coagulation System on the Pathogenesis of Alzheimer's Disease

FXIIa Differentially Regulates Thrombin Generation during Steady State and Vaso-Occlusive Crisis in Sickle Cell Mice

Regulation of the Tumor Microenvironment By High Molecular Weight Kininogen

Defective TAFI Activation in Hemophilia Exacerbates Vascular Remodeling in Hemophilic Arthropathy

Hyperfibrinolysis increases blood–brain barrier permeability by a plasmin- and bradykinin-dependent mechanism

Discovery and Characterization of a Highly Specific Antibody Inhibitor of Factor XIIa, and the Subsequent Generation of a Factor XIIa/Plasma Kallikrein Bispecific Antibody

High Prevalence of Marginal ZONE Lymphoma Among Patients with Acquired C1- Inhibtor Deficiency

Basic Mechanisms of Arterial and Venous Thrombosis

Bradykinin Receptors Regulate Proliferation, Migration and Tube Formation of Endothelial Progenitor Cells

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American Society of Hematology

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ASH Publications

American Society of Hematology

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