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Journal Articles

IGHV sequencing reveals acquired N-glycosylation sites as a clonal and stable event during follicular lymphoma evolution

Mariette Odabashian, Emanuela Carlotti, Shamzah Araf, Jessica Okosun, Filomena Spada, John G. Gribben, Francesco Forconi, Freda K. Stevenson, Mariarita Calaminici, Sergey Krysov

Blood (2020) 135 (11): 834–844.

https://doi.org/10.1182/blood.2019002279

Published: 2020

Includes: Supplemental data

Journal Articles

Inducible Phase Separation of GSK3α As a Mechanism for Asparaginase Resistance in Acute Leukemias

Laura Hinze, Sabine Schreek, Andre Zeug, PhD, Evgeni Ponimaskin, PhD, Roxane Labrosse, MD FRCPC, James Degar, Gabriela Chiosis, PhD, Sung-Yun Pai, MD, Kristen E. Stevenson, MS, Donna S Neuberg, ScD, Beat Bornhauser, PhD, Jean-Pierre Bourquin, MD PhD, Martin Stanulla, MD, Alejandro Gutierrez, MD

Blood (2019) 134 (Supplement_1): 169.

https://doi.org/10.1182/blood-2019-126633

Published: 2019

Journal Articles

Pegasperagase Toxicity in Adult Patients with Acute Lymphoblastic Leukemia: A Single Center Experience Comparing Patients Older and Younger Than 35 Years of Age

Jun H Choi, MD, Jacques Azzi, MD, Tsivia Hochman, MS, Mary Lynn R. Nierodzik, MD, Shella Saint Fleur-Lominy, MD PhD, Maher Abdul Hay, MD

Blood (2019) 134 (Supplement_1): 5067.

https://doi.org/10.1182/blood-2019-129041

Published: 2019

Journal Articles

Glutamine Depletion By Addicted Myeloma Cells Inhibits Osteoblastic Differentiation of Bone Marrow Mesenchymal Stromal Cells Limiting Asparagine Availability: A Possible New Mechanism for Myeloma Bone Disease

Martina Chiu, PhD, Denise Toscani, PhD, Emanuela Vicario, PhD, Roberta Andreoli, PhD, Giuseppe Taurino, MS, Valentina Marchica, MS, Paola Storti, PhD, Massimiliano Bianchi, PhD, Ovidio Bussolati, MD PhD, Nicola Giuliani

Blood (2019) 134 (Supplement_1): 4339.

https://doi.org/10.1182/blood-2019-128034

Published: 2019

Journal Articles

Pegaspargase Can Safely be Administered in Adults Age 40 and Older with Acute Lymphoblastic Leukemia

Ryan J. Daley, PharmD, Sridevi Rajeeve, MD, Charlene C. Kabel, PharmD, Jeremy J. Pappacena, PharmD, BCOP, Sarah E. Stump, PharmD, BCPS, BCOP, Jessica A. Lavery, MS, Martin S. Tallman, MD, Mark B. Geyer, MD, Jae H. Park, MD

Blood (2019) 134 (Supplement_1): 3816.

https://doi.org/10.1182/blood-2019-124727

Published: 2019

Journal Articles

A Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of Recombinant Crisantaspase Produced in Pseudomonas Fluorescens (RC-P) in Healthy Adults

Martha Hernandez-Illas, Tong Lin, Andres Rey, Jack Jenkins, Reddy Chandula, Mi Rim Choi, MD

Blood (2019) 134 (Supplement_1): 3817.

https://doi.org/10.1182/blood-2019-123695

Published: 2019

Journal Articles

Separate Roles of Asparagine and Glutamine in Cytostatic Effect of L-Asparaginase - Stable Isotope Tracing Approach

Katerina Hlozkova, PhD, Alpesh Thakker, PhD, Natividad Alquézar-Artieda, Marketa Zaliova, MD PhD, Jan Trka, Prof., MD PhD, Daniel A Tennant, PhD, Julia Starkova, PhD

Blood (2019) 134 (Supplement_1): 2575.

https://doi.org/10.1182/blood-2019-127911

Published: 2019

Journal Articles

Open-Label, Multicenter, Phase 2/3 Study of Recombinant Crisantaspase Produced in Pseudomonas Fluorescens ( RC-P) in Patients with Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL) Following Hypersensitivity to Escherichia coli -Derived Asparaginases

Luke Maese, DO, Rachel E. Rau, MD, Elizabeth A. Raetz, MD, Tong Lin, Jin Zhu, Pil Kim, Reddy Chandula, Sherrie McClung, Julie Gray, Mi Rim Choi, MD, Mignon L. Loh, MD, Peter C. Adamson

Blood (2019) 134 (Supplement_1): 2586.

https://doi.org/10.1182/blood-2019-123710

Published: 2019

Journal Articles

Mannosylation of the Tumor Immunoglobulin Variable Region Informs Cell of Origin and Environmental Interactions in DLBCL Subsets

Giorgia Chiodin, Joel Allen, Philip J Rock, Enrica Antonia Martino, MD, Beatriz Valle Argos, PhD, Graham Packham, PhD, Patrick Duriez, PhD, Teunis Geijtenbeek, PhD, Carl Figdor, PhD, Richard Burack, MD PhD, Max Crispin, PhD, Freda K Stevenson, PhD, Francesco Forconi, MD DM, PhD FRCPath

Blood (2019) 134 (Supplement_1): 1505.

https://doi.org/10.1182/blood-2019-127159

Published: 2019

Journal Articles

Amino acid metabolism in hematologic malignancies and the era of targeted therapy

Yoko Tabe, Philip L. Lorenzi, Marina Konopleva

Blood (2019) 134 (13): 1014–1023.

https://doi.org/10.1182/blood.2019001034

Published: 2019

Journal Articles

Low Iron Promotes Megakaryocytic Commitment of Megakaryocytic-Erythroid Progenitors in Human and Mice

Juliana Xavier-Ferrucio, PhD, Xiuqi Li, Vanessa Scanlon, PhD, Ping-Xia Zhang, PhD, Nadia Ayala-Lopez, PhD MT(ASCP), Toma Tebaldi, PhD, Stephanie Halene, MD, Karin E. Finberg, MD PhD, Diane S. Krause, MD PhD

Blood (2018) 132 (Supplement 1): 2.

https://doi.org/10.1182/blood-2018-99-115124

Published: 2018

Journal Articles

Contribution of Amino Acid Metabolism to Hematologic Malignancies

Marina Y. Konopleva, MD PhD, Philip L Lorenzi, PhD, Sanaz Ghotbaldini, Yoko Tabe, MD PhD, Tianyu Cai, PhD, Stefano Tiziani, PhD

Blood (2018) 132 (Supplement 1): SCI-10.

https://doi.org/10.1182/blood-2018-99-109469

Published: 2018

Journal Articles

N 6 -Methyladenosine Modification Regulates Cell Metabolism in Acute Myeloid Leukemia

Hengyou Weng, PhD, Huilin Huang, PhD, Huizhe Wu, Mingli Sun, Savanna Stanford, Sean Robinson, zhen-Hua Chen, Xi Qin, Xiaolan Deng, Xi Jiang, PhD, Ying Qing, Chao Shen, PhD, Rui Su, PhD, Minjie Wei, Jianjun Chen, PhD

Blood (2018) 132 (Supplement 1): 880.

https://doi.org/10.1182/blood-2018-99-117455

Published: 2018

Journal Articles

A Phase II Study of Pegylated Asparaginase, Cyclophosphamide, Rituximab, and Dasatinib Added to the UCSF 8707 (Linker 4-drug) Regimen with Liposomal Cytarabine CNS Prophylaxis for Adults with Newly Diagnosed Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL): University of California Hematologic Malignancies Consortium Study (UCHMC) 1401

Matthew J. Wieduwilt, MD PhD, Brian A. Jonas, MD, Gary J. Schiller, MD, Lin Liu, PhD, Carolyn Mulroney, MD, Gabriel N. Mannis, MD, Dimitrios Tzachanis, MD PhD, Januario E. Castro, MD, Edward D Ball, MD, Peter T. Curtin, MD, Charalambos Andreadis, MD, Aaron C. Logan, MD PhD, Jesika Reiner, MPH, Lloyd E. Damon, MD

Blood (2018) 132 (Supplement 1): 4018.

https://doi.org/10.1182/blood-2018-99-117469

Published: 2018

Journal Articles

Monitoring Asparaginase Activity in 21 Patients with Extranodal NK/T-Cell Lymphoma Shows a Very High Proportion of Asparaginase Inactivation

Arnaud Jaccard, MD PhD, Sammara Chaubard, MD, Jean-François Benoist, MD, Lucile Couronne, Laure Philippe, MD, Emmanuel Gyan, MD PhD, Ronan Le Calloch, MD, Aline Moignet Autrel, MD, Rémy Gressin, MD, Jacques Vargaftig, MD PhD, Aline Clavert, MD, Emmanuel Bachy, MD PhD, Olivier Hermine, MD PhD

Blood (2018) 132 (Supplement 1): 5351.

https://doi.org/10.1182/blood-2018-99-118439

Published: 2018

Journal Articles

Dose-Adjusted Intensive Chemotherapy Is Safe and Tolerable in Older Patients with Ph-Negative Acute Lymphoblastic Leukemia

Anne S. Renteria, MD, Sangeetha Venugopal, MD, Bridget Marcellino, MD PhD, Alla Keyzner, MD, Marina Kremyanskaya, MD PhD, Vesna Najfeld, PhD, John Mascarenhas, MD

Blood (2018) 132 (Supplement 1): 5158.

https://doi.org/10.1182/blood-2018-99-115634

Published: 2018

Journal Articles

Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias

Laura Hinze, Maren Pfirrmann, Salmaan Karim, James Degar, Connor McGuckin, Divya Vinjamur, PhD, Sacher Joshua, Kristen E. Stevenson, MS, Donna S Neuberg, ScD, Daniel E. Bauer, MD PhD, Florence Wagner, PhD, Kimberly Stegmaier, MD, Alejandro Gutierrez, MD

Blood (2018) 132 (Supplement 1): 891.

https://doi.org/10.1182/blood-2018-99-113794

Published: 2018

Journal Articles

The Glutaminase Activity of L-Asparaginase Mediates Suppression of Asns Upregulation

Wai Kin Chan, PhD, Lin Tan, MS, Karine Harutyunyan, PhD, Di Du, PhD, Leona Martin, MS, Eric Yin, MS, Marina Y. Konopleva, MD PhD, John Weinstein, MD PhD, Philip L Lorenzi, PhD

Blood (2018) 132 (Supplement 1): 3959.

https://doi.org/10.1182/blood-2018-99-117818

Published: 2018

Journal Articles

Increased Methylation of Deamidated Asparagines and Aspartates in Stored Red Blood Cells from Glucose 6-Phosphate Dehydrogenase-Deficient Blood Donors

Blood (2018) 132 (Supplement 1): 2543.

https://doi.org/10.1182/blood-2018-99-119262

Published: 2018

Journal Articles

EVI1 in Acute Myeloid Leukemia Triggers Metabolic Reprograming Associated with Leukemogenesis and Increases Sensitivity to L-Aspalaginase

Yusuke Saito, MD PhD, Daisuke Sawa, MD, Mariko Kinoshita, MD, Ai Yamada, MD, Sachiyo Kamimura, MD, Kazuhiro Morishita, MD PhD, Tomoyoshi Soga, PhD, Hiroshi Moritake, MD PhD

Blood (2018) 132 (Supplement 1): 2601.

https://doi.org/10.1182/blood-2018-99-111581

Published: 2018

NARROW

IGHV sequencing reveals acquired N-glycosylation sites as a clonal and stable event during follicular lymphoma evolution

Inducible Phase Separation of GSK3α As a Mechanism for Asparaginase Resistance in Acute Leukemias

Pegasperagase Toxicity in Adult Patients with Acute Lymphoblastic Leukemia: A Single Center Experience Comparing Patients Older and Younger Than 35 Years of Age

Glutamine Depletion By Addicted Myeloma Cells Inhibits Osteoblastic Differentiation of Bone Marrow Mesenchymal Stromal Cells Limiting Asparagine Availability: A Possible New Mechanism for Myeloma Bone Disease

Pegaspargase Can Safely be Administered in Adults Age 40 and Older with Acute Lymphoblastic Leukemia

A Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of Recombinant Crisantaspase Produced in Pseudomonas Fluorescens (RC-P) in Healthy Adults

Separate Roles of Asparagine and Glutamine in Cytostatic Effect of L-Asparaginase - Stable Isotope Tracing Approach

Open-Label, Multicenter, Phase 2/3 Study of Recombinant Crisantaspase Produced in Pseudomonas Fluorescens ( RC-P) in Patients with Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL) Following Hypersensitivity to Escherichia coli -Derived Asparaginases

Mannosylation of the Tumor Immunoglobulin Variable Region Informs Cell of Origin and Environmental Interactions in DLBCL Subsets

Amino acid metabolism in hematologic malignancies and the era of targeted therapy

Low Iron Promotes Megakaryocytic Commitment of Megakaryocytic-Erythroid Progenitors in Human and Mice

Contribution of Amino Acid Metabolism to Hematologic Malignancies

N 6 -Methyladenosine Modification Regulates Cell Metabolism in Acute Myeloid Leukemia

Monitoring Asparaginase Activity in 21 Patients with Extranodal NK/T-Cell Lymphoma Shows a Very High Proportion of Asparaginase Inactivation

Dose-Adjusted Intensive Chemotherapy Is Safe and Tolerable in Older Patients with Ph-Negative Acute Lymphoblastic Leukemia

Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias

The Glutaminase Activity of L-Asparaginase Mediates Suppression of Asns Upregulation

Increased Methylation of Deamidated Asparagines and Aspartates in Stored Red Blood Cells from Glucose 6-Phosphate Dehydrogenase-Deficient Blood Donors

EVI1 in Acute Myeloid Leukemia Triggers Metabolic Reprograming Associated with Leukemogenesis and Increases Sensitivity to L-Aspalaginase

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American Society of Hematology

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ASH Publications

American Society of Hematology

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