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Journal Articles

CRISPR-Cas9 Screen Identifies Me2 , a Mitochondrial Malic Enzyme, As a Molecule Relevant for MCL1 Inhibitor Resistance in AML

Fumihiko Nakao, MD, Takuji Yamauchi, MD PhD, Yuichiro Semba, MD PhD, Jumpei Nogami, PhD, Koichi Akashi, MD PhD, Takahiro Maeda, MD PhD

Blood (2019) 134 (Supplement_1): 912.

https://doi.org/10.1182/blood-2019-129237

Published: 2019

Journal Articles

Synergistic Pre-Clinical Activity of Targeted Inhibition of KDM1A and BET Proteins Against Human AML Blast Progenitor Cells

Warren Fiskus, BSc, PhD, Christopher Peter Mill, PhD BA, Raffaella Soldi, Roulan Han, Dyana T. Saenz, PhD, Agnieszka J Nowak, Baohua Sun, MD PhD, David N Saenz, Courtney D. DiNardo, MD MSc, Gautam Borthakur, MD, Tapan M. Kadia, MD, Wendy Jin, Thurika Ganesh, Vaishnavi Rao, Joseph David Khoury, MD, Sunil Sharma, MD, Kapil N. Bhalla, MD

Blood (2018) 132 (Supplement 1): 3930.

https://doi.org/10.1182/blood-2018-99-114198

Published: 2018

Journal Articles

PDK1 Regulates HSCs Via the Foxo Pathway during Murine Fetal Liver Hematopoiesis

Weiping Yuan, PhDMD

Blood (2017) 130 (Supplement 1): 1135.

https://doi.org/10.1182/blood.V130.Suppl_1.1135.1135

Published: 2017

Journal Articles

Adult "Triple Negative" ACUTE Lymphoblastic Leukemia Genome Wide Characterization

Blood (2017) 130 (Supplement 1): 2720.

https://doi.org/10.1182/blood.V130.Suppl_1.2720.2720

Published: 2017

Journal Articles

Murine Donor 1928z CAR T Cells Exert Potent Graft-Versus-Lymphoma Activity without Graft-Versus-Host-Disease

Melody Smith, MD, Arnab Ghosh, MD PhD, Scott James, MD PhD, Marco L Davila, MDPhD, Enrico Velardi, PhD, Kimon V. Argyropoulos, MD, Gertrude Gunset, Andrea Schietinger, PhD, Michel W. Sadelain, MD PhD, Marcel van den Brink, MD PhD

Blood (2016) 128 (22): 653.

https://doi.org/10.1182/blood.V128.22.653.653

Published: 2016

Journal Articles

Analysis of the Expression of PHTF1 and Related Genes in Acute Lymphoblastic Leukemia

Xin Huang, Suxia Geng, Jianyu Weng, Zesheng Lu, Linji Zeng, Minming Li, Chengxin Deng, Xiuli Wu, Yangqiu Li, Xin Du

Blood (2015) 126 (23): 4988.

https://doi.org/10.1182/blood.V126.23.4988.4988

Published: 2015

Journal Articles

Labile Plasma Iron (LPI), More Practical and More Sensitive to Iron Overload in Myelodysplastic Syndromes

Chunkang Chang, MDPhD, Shucheng Gu, MD, Juan Guo, MD, Youshan Zhao, MD, Chengming Fei, MD, Xiao Li, MD PhD

Blood (2015) 126 (23): 5230.

https://doi.org/10.1182/blood.V126.23.5230.5230

Published: 2015

Journal Articles

SRC-3 Ubiquination, Mediated By Cullin3, Potentiates Gambogic Acid-Induced Apoptosis in Non-Hodgkin's Lymphoma

Zichu Zhao, Lu Wen, Sha Yi, Xia Zhang, Jingyu Hu, Jun Ruan, Fei Zhao, Guohui Cui, Jun Fang, Yan Chen

Blood (2015) 126 (23): 4854.

https://doi.org/10.1182/blood.V126.23.4854.4854

Published: 2015

Journal Articles

Caspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in mice

Elise Peterson Lu, Michael McLellan, Li Ding, Robert Fulton, Elaine R. Mardis, Richard K. Wilson, Christopher A. Miller, Peter Westervelt, John F. DiPersio, Daniel C. Link, Matthew J. Walter, Timothy J. Ley, Timothy A. Graubert

Blood (2014) 124 (26): 3887–3895.

https://doi.org/10.1182/blood-2014-06-582551

Published: 2014

Includes: Supplemental data

Journal Articles

Silencing of HSP70 and TRIAP1 Genes in Multiple Myeloma Cell Lines Induces Apoptosis through Apaf-1/Caspase 9 Pathway: New Potential Targets on the Way?

Veruska Lia Fook Alves, MsC, Gisele Wally Braga Colleoni, Daniela Bertolli Zanatta, Bryan E. Strauss

Blood (2014) 124 (21): 5175.

https://doi.org/10.1182/blood.V124.21.5175.5175

Published: 2014

Journal Articles

Blast Crisis CML Cells Require IFN-γ Conditioning For Effective GVL Whereas Chronic Phase CML Cells Do Not: An Explanation For Chronic Phase CML GVL-Sensitivity

Catherine Matte-Martone, Warren D Shlomchik, MD

Blood (2013) 122 (21): 2013.

https://doi.org/10.1182/blood.V122.21.2013.2013

Published: 2013

Journal Articles

Functional Studies Of H sp70 Gene Expression In Multiple Myeloma Cell Lines Suggest That This Gene Inhibition Can Be a Potential Therapeutic Target, Independent Of 17p/p53 Status

Veruska Lia Fook Alves, Walter Moises Tobias Braga, M.D., Daniela Bertolli Zanatta, Fabricio de Carvalho, Maria de Lourdes Chauffaille, Bryan E. Strauss, Gisele Wally Braga Colleoni, MD

Blood (2013) 122 (21): 3771.

https://doi.org/10.1182/blood.V122.21.3771.3771

Published: 2013

Journal Articles

Harnessing Gene Expression Profiling In Search Of New Candidate Genes For Ara-C Resistance In Acute Myeloid Leukemia

Ajay Abraham, M.Sc, Savitha Varatharajan, M.Sc, Sreeja Karathedath, M.Sc, Shaji R Velayudhan, Ph.D, Alok Srivastava, MD, Vikram Mathews, MD, Poonkuzhali Balasubramanian, Ph.D

Blood (2013) 122 (21): 1299.

https://doi.org/10.1182/blood.V122.21.1299.1299

Published: 2013

Journal Articles

Transcriptome Analysis Reveals Molecular Profiles Associated with Evolving Steps of Monoclonal Gammopathies.

Lucía López Corral, Luis Antonio Corchete, Maria Victoria Mateos, MD, PhD, Ramon Garcia-Sanz, Encarna Fermiñán, Juan José Lahuerta, Joan Blade, MD, Albert Oriol, Ana Isabel Teruel, Maria Luz Martino, MD, Jose Hernández, Jesús M Hernández-Rivas, Jesus F San Miguel, Norma Gutierrez

Blood (2012) 120 (21): 2914.

https://doi.org/10.1182/blood.V120.21.2914.2914

Published: 2012

Journal Articles

Cancer-Testis Antigen MAGE-C2/CT10 Promotes Proliferation and Enhances Resistance to p53 Mediated Apoptosis in Multiple Myeloma

Nesrine Lajmi, Julia Templin, Sara Yousef, Tim Luetkens, Stefanie Spock, York Hildebrandt, Katrin Bartels, Yanran Cao, Carsten Bokemeyer, Nicolaus Kröger, Djordje Atanackovic

Blood (2012) 120 (21): 1808.

https://doi.org/10.1182/blood.V120.21.1808.1808

Published: 2012

Journal Articles

Title: Promoter Methylation of Selected Genes and Response to Azacitidine (AZ) Therapy in Patients with Non-BCR-ABL Myeloproliferative Disorders (MPDs)

Nicholas Achille, BS, Laura Michaelis, MD, Scott E. Smith, MD, PhD, FACP, Eliza Germano, Nancy J. Zeleznik-Le, PhD, Sucha Nand, MD

Blood (2011) 118 (21): 4625.

https://doi.org/10.1182/blood.V118.21.4625.4625

Published: 2011

Journal Articles

Inhibition of Phosphatidylinositol 3-Kinase Is Effective to Suppress the Growth of CD20-Negative Refractory Diffuse Large B-Cell Lymphoma Cells

Tsuyoshi Nakamaki, MD, Kunihiko Fukuchi, MD, Hidetoshi Nakashima, MD, Hirotsugu Ariizumi, MD, Takashi Maeda, MD, Bungo Saito, MD, Kouji Yanagisawa, MD, Shigeru Tomoyasu, MD, Eisuke Shiozawa, MD, Toshiko Yamochi-Onizuka, MD, Hidekazu Ota, MD

Blood (2011) 118 (21): 2421.

https://doi.org/10.1182/blood.V118.21.2421.2421

Published: 2011

Journal Articles

Protein Degradation and Resultant Hsp90 Dephosphorylation as An Alternative C-KIT Kinase Inhibition Strategy

Bo Zhang, Haitong Fang, Xiaofen Pan, Jun Xie, Yonglong Chen, Sai-Juan Chen, Guangbiao Zhou, MD, PhD

Blood (2010) 116 (21): 4361.

https://doi.org/10.1182/blood.V116.21.4361.4361

Published: 2010

Journal Articles

The HDAC INHIBITOR ITF2357 MODULATES KEY HEMATOPOIETIC GENES in JAK2 V617F CELLS From MYELOPROLIFERATIVE Neoplasm PATIENTS

Ariel Amaru, MD, Katia Todoerti, PhD, Anna Pellicioli, Luca Donadoni, Giacomo Tuana, Olga Pedrini, Guido Finazzi, MD, Antonino Neri, MD, Gianluca Fossati, Alessandro Rambaldi, MD, Martino Introna, MD, Luigia Lombardi, Josée Golay, PhD

Blood (2010) 116 (21): 797.

https://doi.org/10.1182/blood.V116.21.797.797

Published: 2010

Journal Articles

Enzastaurin Treatment Affects Multiple Regulatory Pathways at Transcriptome and Cellular Proteome Level of Mantle Cell Lymphoma

Marc Weinkauf, Grit Hutter, Yvonne Zimmermann, Malte Rieken, Alessandro Pastore, Elena Hartmann, Andreas Rosenwald, Wolfgang Hiddemann, MD, Martin H. Dreyling, MD

Blood (2010) 116 (21): 2893.

https://doi.org/10.1182/blood.V116.21.2893.2893

Published: 2010

NARROW

CRISPR-Cas9 Screen Identifies Me2 , a Mitochondrial Malic Enzyme, As a Molecule Relevant for MCL1 Inhibitor Resistance in AML

Synergistic Pre-Clinical Activity of Targeted Inhibition of KDM1A and BET Proteins Against Human AML Blast Progenitor Cells

PDK1 Regulates HSCs Via the Foxo Pathway during Murine Fetal Liver Hematopoiesis

Adult "Triple Negative" ACUTE Lymphoblastic Leukemia Genome Wide Characterization

Murine Donor 1928z CAR T Cells Exert Potent Graft-Versus-Lymphoma Activity without Graft-Versus-Host-Disease

Analysis of the Expression of PHTF1 and Related Genes in Acute Lymphoblastic Leukemia

Labile Plasma Iron (LPI), More Practical and More Sensitive to Iron Overload in Myelodysplastic Syndromes

SRC-3 Ubiquination, Mediated By Cullin3, Potentiates Gambogic Acid-Induced Apoptosis in Non-Hodgkin's Lymphoma

Caspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in mice

Silencing of HSP70 and TRIAP1 Genes in Multiple Myeloma Cell Lines Induces Apoptosis through Apaf-1/Caspase 9 Pathway: New Potential Targets on the Way?

Blast Crisis CML Cells Require IFN-γ Conditioning For Effective GVL Whereas Chronic Phase CML Cells Do Not: An Explanation For Chronic Phase CML GVL-Sensitivity

Functional Studies Of H sp70 Gene Expression In Multiple Myeloma Cell Lines Suggest That This Gene Inhibition Can Be a Potential Therapeutic Target, Independent Of 17p/p53 Status

Harnessing Gene Expression Profiling In Search Of New Candidate Genes For Ara-C Resistance In Acute Myeloid Leukemia

Transcriptome Analysis Reveals Molecular Profiles Associated with Evolving Steps of Monoclonal Gammopathies.

Cancer-Testis Antigen MAGE-C2/CT10 Promotes Proliferation and Enhances Resistance to p53 Mediated Apoptosis in Multiple Myeloma

Title: Promoter Methylation of Selected Genes and Response to Azacitidine (AZ) Therapy in Patients with Non-BCR-ABL Myeloproliferative Disorders (MPDs)

Inhibition of Phosphatidylinositol 3-Kinase Is Effective to Suppress the Growth of CD20-Negative Refractory Diffuse Large B-Cell Lymphoma Cells

Protein Degradation and Resultant Hsp90 Dephosphorylation as An Alternative C-KIT Kinase Inhibition Strategy

The HDAC INHIBITOR ITF2357 MODULATES KEY HEMATOPOIETIC GENES in JAK2 V617F CELLS From MYELOPROLIFERATIVE Neoplasm PATIENTS

Enzastaurin Treatment Affects Multiple Regulatory Pathways at Transcriptome and Cellular Proteome Level of Mantle Cell Lymphoma

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American Society of Hematology

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American Society of Hematology

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