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Journal Articles

Proteasome Inhibition Leads to Dephosphorylation and Downregulation of Protein Expression of Members of the Akt/mTOR Pathway In MCL

Grit Hutter, Yvonne Zimmermann, Malte Rieken, Elena Hartmann, Wolfgang Hiddemann, MD, PhD, Andreas Rosenwald, Martin H. Dreyling, MD
Journal: Blood
Blood (2010) 116 (21): 4449.
https://doi.org/10.1182/blood.V116.21.4449.4449
Published: 2010
Journal Articles

Enzastaurin Treatment Affects Multiple Regulatory Pathways at Transcriptome and Cellular Proteome Level of Mantle Cell Lymphoma

Marc Weinkauf, Grit Hutter, Yvonne Zimmermann, Malte Rieken, Alessandro Pastore, Elena Hartmann, Andreas Rosenwald, Wolfgang Hiddemann, MD, Martin H. Dreyling, MD
Journal: Blood
Blood (2010) 116 (21): 2893.
https://doi.org/10.1182/blood.V116.21.2893.2893
Published: 2010
Journal Articles

Synergistic Antilymphoma Effect of Protein Kinase C Beta (PKCĪ²) and mTOR Inhibition in Mantle Cell Lymphoma.

Grit Hutter, Yvonne Zimmermann, Malte Rieken, Elena Hartmann, MD, Vindi Jurinovic, Andreas Rosenwald, Marc Weinkauf, Wolfgang Hiddemann, Martin H. Dreyling
Journal: Blood
Blood (2009) 114 (22): 4780.
https://doi.org/10.1182/blood.V114.22.4780.4780
Published: 2009
Journal Articles

Proteomic Analysis of Pkc-Beta Inhibitor Enzastaurin-Treated Mantle Cell Lymphoma

Marc Weinkauf, Malte Rieken, Alessandro Pastore, Wolfgang Hiddemann, Martin H. Dreyling, MD
Journal: Blood
Blood (2008) 112 (11): 4982.
https://doi.org/10.1182/blood.V112.11.4982.4982
Published: 2008
Journal Articles

TRAIL Receptor 1 and TRAIL Receptor 2 Monoclonal Antibodies Induce Apoptosis and Increase Susceptibility to Cytostatic Agents in Mantle Cell Lymphoma.

Malte Rieken, MD, Alessandro Pastore, MD, Oliver Weigert, MD, Marc Weinkauf, MD, Grit Hutter, MD, Yvonne Zimmermann, MD, Wolfgang Hiddemann, MD, Martin Dreyling, MD
Journal: Blood
Blood (2006) 108 (11): 4751.
https://doi.org/10.1182/blood.V108.11.4751.4751
Published: 2006
Journal Articles

Inhibition of Proteasome Is Associated with Early Alterations of Cell Cycle Regulators and Induces Synergistic Antitumour Activities in Mantle Cell Lymphoma in a Sequence Dependent Manner.

Alessandro Pastore, Malte Rieken, Oliver Weigert, MD, Yvonne Zimmermann, Grit Hutter, PhD, Marc Weinkauf, Wolfgang Hiddemann, MD, PhD, Martin Dreyling, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 2409.
https://doi.org/10.1182/blood.V106.11.2409.2409
Published: 2005
Journal Articles

Inhibition of Protein Kinase C beta by Enzastaurin (LY 317615) Induces Alterations of Key Regulators of Cell Cycle and Apoptosis in Mantle Cell Lymphoma and Synergizes with Chemotherapeutic Agents in a Sequence Dependent Manner.

Malte Rieken, Oliver Weigert, MD, Alessandro Pastore, Grit Hutter, PhD, Yvonne Zimmermann, Marc Weinkauf, Wolfgang Hiddemann, MD, PhD, Martin Dreyling, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 2416.
https://doi.org/10.1182/blood.V106.11.2416.2416
Published: 2005
Journal Articles

Altered Cellular Protein Levels of Tumor Suppressor Genes and Heat Shock Elements (TRAP1) Indicate Sensitivity to the Proteasome Inhibitor Bortezomib (VelcadeĀ®) in Mantle Cell Lymphoma.

Marc Weinkauf, Malte Rieken, Alessandro Pastore, Elena Hartmann, Andreas Rosenwald, MD, Wolfgang Hiddemann, MD, Martin H. Dreyling, MD
Journal: Blood
Blood (2005) 106 (11): 2424.
https://doi.org/10.1182/blood.V106.11.2424.2424
Published: 2005
Journal Articles

Cell Cycle Dysregulation Represents an Early Effect of the Proteasome Inhibitor Bortezomib in Mantle Cell Lymphoma.

Grit Hutter, MSc, Yvonne Zimmermann, Malte Rieken, Marc Weinkauf, Oliver Weigert, MD, Wolfgang Hiddemann, MD, PhD, Martin H. Dreyling, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 2287.
https://doi.org/10.1182/blood.V104.11.2287.2287
Published: 2004