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Journal Articles

Synergistic Effect of Carfilzomib and Metformin in Vascular Plasticity; The Emerging Role of Autophagy

Panagiotis Efentakis, PhD, Ioanna Andreadou, PhD, Panagiota-Efstathia Nikolaou, PhD, Claudius Witzler, Svenja Siemer, Eftathios Kastritis, Philip Wenzel, MD PhD, Meletios A. Dimopoulos, MD, Evangelos Terpos, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3797.
https://doi.org/10.1182/blood-2019-123522
Published: 2019
Journal Articles

High Risk Genomic Alterations Identified at the Time of Diagnosis Are Strongly Associated with MRD and Subsequent Poor Outcomes in AYA ALL Patients Treated on a Pediatric Inspired Chemotherapy Regimen

David T Yeung, PhDBSc,FRACP,FRCPA,MBBS, Matthew Greenwood, MBBS, FRACP, FRCPA, Jacqueline Rhen, BSc MSc MD, Susan L Heatley, PhD MD, Barbara McClure, BSc (Hons) PhD, Laura N Eadie, BSc (Hons) PhD, Jimmy Breen, BSc (Hons) PhD, Caitlin Schutz Schutz, BSc (Hons), Toby N Trahair, MBBS FRACP PhD, Andrew H. Wei, PhD FRACP, FRCPA, MBBS, Luciano Dalla-Pozza, MBBS FRACP, Rosemary Sutton, BSc MSc PhD, Kenneth F Bradstock, BSc(MD, MBBS, PhD FRACP, FRCPA, Michael Philip Osborn, MB, BS, Deborah L. White, PhD FFSc (RCPA)
Journal: Blood
Blood (2019) 134 (Supplement_1): 3949.
https://doi.org/10.1182/blood-2019-127788
Published: 2019
Journal Articles

Platelet RNA Splicing Profiles Can Distinguish IgM MGUS Patients from Healthy Individuals

Mick J.M. Van Eijs, MSc, Nicolette C. Notermans, MD PhD, Tom Würdinger, PhD, Monique C. Minnema, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3771.
https://doi.org/10.1182/blood-2019-124325
Published: 2019
Journal Articles

Alternative Splicing and Intronic Polyadenylation Post-Transcriptionally Regulate CSF3R Via a Cryptic Exon

Lawrence J Druhan, PhD, Amanda Lance, MS, Alicia Hamilton, Nury M Steuerwald, PhD, Elise Tjaden, Belinda R Avalos, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2462.
https://doi.org/10.1182/blood-2019-129102
Published: 2019
Journal Articles

Modeling the Behavior of Hematopoietic Compartments from Stem to Red Cells in Murine Steady State and Stress Hematopoiesis

Celine Bonnet, BSc, Panhong Gou, BSc, Vincent Bensaye, PhD Associate Professor, Catherine Lacout, Ingeneer, Karine Bailly, Ingeneer, Marie-helene Schlagetter, MD PhD, Evelyne Lauret, PhD, Sylvie Meleard, PhD Professor, Stephane Giraudier, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2224.
https://doi.org/10.1182/blood-2019-123704
Published: 2019
Journal Articles

MEK Inhibition with Trametinib in Patients with Non-Langerhans Cell Histiocytosis

Filip Janku, MD PhD, Harsh Patel, BS, Vaijayanthi Kandadai Raghavan, Aaron Goodman, Tamara G. Barnes, Razelle Kurzrock, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2319.
https://doi.org/10.1182/blood-2019-126342
Published: 2019
Journal Articles

Mechanistic Evaluation of Efficacy Using Biomarkers of the Oral, Small Molecule Factor D Inhibitor, Danicopan (ACH-4471), in Untreated Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH)

Antonio M. Risitano, MD PhD, Jong Wook Lee, MD PhD, Rosario Notaro, MD, Robert A. Brodsky, MD, Austin Kulasekararaj, MBBS MDMRCP FRCPath, Jaroslaw P. Maciejewski, MD PhD, Mingjun Huang, PhD, Michael Geffner, MD, Peter Browett, BMedSci, MBChB, FRACP, FRCPA
Journal: Blood
Blood (2019) 134 (Supplement_1): 2226.
https://doi.org/10.1182/blood-2019-124837
Published: 2019
Journal Articles

Procoagulant Microparticles Derived from Myeloma Plasma Cells Have a Determinant Role in the Hypercoagulable State Associated with Multiple Myeloma. a Modelization in Vitro Study

Loula Papageorgiou, Patrick Van Dreden, PhD, Meletios A. Dimopoulos, MD, Annette Larsen, Mohamad Mohty, MD PhD, Ismail Elalamy, MD PhD, Grigorios T. Gerotziafas
Journal: Blood
Blood (2019) 134 (Supplement_1): 2425.
https://doi.org/10.1182/blood-2019-124650
Published: 2019
Journal Articles

Clinical and Cytogenomic Features of Lymphoblastic Leukemia with Intrachromosomal Amplification of Chromosome 21 (iAMP21) in the Context of Constitutional Ring Chromosome 21

Tatiana Tvrdik, PhD MSc, Kristian T. Schafernak, MD MPH, Jeffrey R Jacobsen, MD, Reha Toydemir, MD PhD, Alexandra M Walsh, MD, Bo Hong, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5208.
https://doi.org/10.1182/blood-2019-123766
Published: 2019
Journal Articles

Clinical and Laboratory Features Associated with Flow Cytometric CD49f Expression in Pediatric B Cell Acute Lymphoblastic Leukemia

Eric McGinnis, MD BSc, David Yang, BMLSc, Nina Rolf, MD PhD, Gregor S. D. Reid, PhD, Chinten J. Lim, PhD, Suzanne M. Vercauteren, MD PhD FRCPC
Journal: Blood
Blood (2019) 134 (Supplement_1): 5209.
https://doi.org/10.1182/blood-2019-123590
Published: 2019
Journal Articles

Resistance to Axicabtagene Ciloleucel Therapy in T Cell/Histiocyte-Rich Large B Cell Lymphoma

Jonathan Trujillo, MD PhD, James Godfrey, MD, Michael R. Bishop, MD, Peter A. Riedell, MD, Justin Kline, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5238.
https://doi.org/10.1182/blood-2019-131941
Published: 2019
Journal Articles

R-m-NHL-BFM-90/R-EPOCH Protocol in the Treatment of Patients with Primary Mediastinal Lymphoma: First Results

Nelly G Gabeeva, PhD, Darya A Koroleva, Svetlana A Tatarnikova, Anna K Smolyaninova, Svetlana Smirnova, MD PhD, Elena E Nikulina, Alla M. Kovrigina, MD PhD, Andrey B Sudarikov, PhD DSc, Eugene E. Zvonkov, MD PhD, Valery G. Savchenko, MD PhD academician
Journal: Blood
Blood (2019) 134 (Supplement_1): 5334.
https://doi.org/10.1182/blood-2019-127944
Published: 2019
Journal Articles

Metastatic Lymphoepithelioma-like Carcinoma Treated with PD1-Antibody:Is Epstein-Barr Virus Eradication the Main Mechanism in 2 Refractory Cases in Children?

Haixia Guo, MD PhD, Xuedong Wu, MD PhD, Na LI, Jian LI
Journal: Blood
Blood (2019) 134 (Supplement_1): 5615.
https://doi.org/10.1182/blood-2019-129871
Published: 2019
Journal Articles

Significance of Modified Risk Stratification Msmart 3.0 and Autologous Stem Cell Transplantation for Patients with Newly Diagnosed Multiple Myeloma

Andrey Garifullin, MD, Sergei Voloshin, MD PhD, Vasily Shuvaev, MD, Irina Martynkevich, MD PhD, Elizaveta Kleina, Alexander Chechetkin, Stanislav Bessmeltcev, Anastasiya Kuzyaeva, Alexander Sсhmidt, Alexey Kuvshinov, MD, Irina Pavlova
Journal: Blood
Blood (2019) 134 (Supplement_1): 5593.
https://doi.org/10.1182/blood-2019-130092
Published: 2019
Journal Articles

Characterization of the "Immune Evasion" Phenotype of Richter Syndrome and the Implications for Immune-Checkpoint Inhibitor Therapy

Clare Gould, MBBS, Jennifer Lickiss, MSc, BSc, Yamuna Kankanige, Satwica Yerneni, MS, John Markham, Costas K. Yannakou, MBBS (Hons), FRACP, FRCPA, Diego Villa, MD MPH, Graham W Slack, MD, Collin Chin, MBBS, Constantine S. Tam, MBBS (Hons), MD, Stephen Lade, MBBS, FRCPA, Niles Elizabeth Nelson, BSc, MBBS, Paul J Neeson, BSc, PhD, John F. Seymour, MBBS, PhD FRACP, Michael Dickinson, MBBS,FRACP,FRCPA, David Alan Westerman, MBBS, FRCPA, FRACP, Piers Blombery, MBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 4290.
https://doi.org/10.1182/blood-2019-127800
Published: 2019
Journal Articles

Prognostic Significance of Reduced BCAS4 expression in Bone Marrow Cells of Patients with Myelodysplastic Syndromes

Masayuki Shiseki, MD PhD, Mayuko Ishii, Mari Ohwashi, Kentaro Yoshinaga, MD PhD, Naoki Mori, MD PhD, Junji Tanaka, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4258.
https://doi.org/10.1182/blood-2019-124738
Published: 2019
Journal Articles

CRISPR/dCas9 (D10A) -Mediated Hb CS Gene Editing and Identification of Genetically Modified Fibroblasts

Lian Yu, Wei Hao Wu, WANG Shunqing, Ken H. Young, Funeng Jiang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5754.
https://doi.org/10.1182/blood-2019-129931
Published: 2019
Journal Articles

Title: SNP Microarray Reveals Predicted Outcomes of a Novel High Risk AML Subgroup with ERG Amplification

Sandra Mazzoni, BS,DO,MT(ASCP), Brian T. Hess, MD, Cynthia Schandl, MD PhD, Iya Znoyko, PhD, Georges Nahhas, Dongjun Chung, Assistant Professor, PhD, Yanna Ding, MD PhD, Daynna Wolff, PhD FACMG
Journal: Blood
Blood (2019) 134 (Supplement_1): 2737.
https://doi.org/10.1182/blood-2019-121408
Published: 2019
Journal Articles

Characteristics and Clinical Outcomes of Patients with Acute Lymphoblastic Leukemia with KMT2A ( MLL ) Rearrangement

Guillaume Richard-Carpentier, MD, Hagop M. Kantarjian, MD, Guilin Tang, MD, C. Cameron Yin, MD PhD, Joseph D. Khoury, MD, Ghayas C. Issa, MD, Nitin Jain, MD, Farhad Ravandi, MD, Nicholas J. Short, MD, Courtney D. DiNardo, MDMSc, Koichi Takahashi, MD, Maro Ohanian, DO, Gautam M. Borthakur, MD, Marina Y Konopleva, MD PhD, Naval G. Daver, MD, Zeev E. Estrov, MD, Yesid Alvarado, MD, Alessandra Ferrajoli, MD, Tapan M. Kadia, MD, Guillermo Garcia-Manero, MD, Srdan Verstovsek, MD PhD, Rebecca Garris, MSc, Jorge E. Cortes, MD, Susan O'Brien, MD, Elias Jabbour, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2582.
https://doi.org/10.1182/blood-2019-130864
Published: 2019
Journal Articles

Molecular Classification of AML-MRC Reveals a Distinct Profile and Identifies MRC-like Patients with Poor Overall Survival

Constance Baer, PhD, Wencke Walter, PhD, Anna Stengel, PhD, Stephan Hutter, PhD, Manja Meggendorfer, PhD, Wolfgang Kern, MD, Claudia Haferlach, MD, Torsten Haferlach, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2735.
https://doi.org/10.1182/blood-2019-128234
Published: 2019