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Journal Articles

Wilms Tumor 1 Gene Mutations in Adult Acute T-Lymphoblastic Leukemia

Sandra Heesch, MS, Nicola Goekbuget, MD, Jutta Ortiz Tanchez, Cornelia Schlee, MS, Stefan Schwartz, Thomas Burmeister, MD, Dieter Hoelzer, MD, PhD, Eckhard Thiel, MD, PhD, Wolf K Hofmann, MD, Claudia D Baldus, MD

Blood (2008) 112 (11): 2516.

https://doi.org/10.1182/blood.V112.11.2516.2516

Published: 2008

Journal Articles

Identification of ERG Specific Target Genes by Genome-Wide Screening in T-Lymphoblastic Leukemia

Liliana H Mochmann, MS, Konrad Neumann, PhD, Juliane Bock, Jutta Ortiz Tanchez, MS, Arend Bohne, PhD, Eckhard Thiel, MD, PhD, Wolf K Hofmann, MD, Claudia D Baldus, MD

Blood (2008) 112 (11): 3788.

https://doi.org/10.1182/blood.V112.11.3788.3788

Published: 2008

Journal Articles

Differential Expression of ERG Isoforms in Acute Myeloid and T-Lymphoblastic Leukemia Is Regulated by DNA-Methylation.

Claudia D. Baldus, MD, Cornelia Schlee, MS, Julia Thibaut, MS, Sandra Heesch, MS, Arend Bohne, PhD, Eckhard Thiel, MD, Wolf K. Hofmann, MD

Blood (2007) 110 (11): 2126.

https://doi.org/10.1182/blood.V110.11.2126.2126

Published: 2007

Journal Articles

Mutations in Specific NOTCH1 Domains Convey a Distinct Phenotype in Adult Acute T-Lymphoblastic Leukemia.

Julia Thibaut, MS, Nicola Goekbuget, MD, Peter Martus, PhD, Thomas Burmeister, MD PhD, Stefan Schwartz, MD, Dieter Hoelzer, MD, Eckhard Thiel, MD, Wolf K. Hofmann, MD, Claudia D. Baldus, MD

Blood (2007) 110 (11): 152.

https://doi.org/10.1182/blood.V110.11.152.152

Published: 2007

Journal Articles

Immunosuppression for Patients with Low and Intermediate Risk Myelodysplastic Syndrome: A Prospective Randomized Multicenter Trial Comparing Antithymocyte Globulin + Cyclosporine with Best Supportive Care: SAKK 33/99.

Jakob R. Passweg, Aristoteles Giagounidis, Mathew Simcock, Carlo Aul, Christiane Dobbelstein, Michael Stadler, Gert Ossenkoppele, Wolf K. Hofmann, Andre Tichelli, Arnold Ganser

Blood (2007) 110 (11): 1461.

https://doi.org/10.1182/blood.V110.11.1461.1461

Published: 2007

Journal Articles

Low Expression of IL-15 in Adult B-Lineage Acute Lymphoblastic Leukemia Is Associated with Central Nervous System Involvement at Initial Presentation.

Shuling Wu, MD, Thomas Burmeister, MD, PhD, Claudia Baldus, MD, PhD, Stefen Schwartz, MD, Michael Notter, MD, Nicola Goekbuget, MD, Dieter Hoelzer, MD, Wolf K. Hofmann, MD, Eckhard Thiel, MD

Blood (2007) 110 (11): 2389.

https://doi.org/10.1182/blood.V110.11.2389.2389

Published: 2007

Journal Articles

Analysis of Immunological and Clinical Response Kinetics to WT1 Peptide Vaccine in Patients with AML and MDS: Need for Supplementation of IWG Response Criteria?.

Ulrich Keilholz, MD, Anne Letsch, MD, Antonia Busse, MD, Annemarie Asemissen, MD, Igor W. Blau, MD, Wolf K. Hofmann, MD, Lutz Uharek, MD, Eckhard Thiel, MD, Carmen Scheibenbogen, MD

Blood (2007) 110 (11): 902.

https://doi.org/10.1182/blood.V110.11.902.902

Published: 2007

Journal Articles

Detailed Genome-Wide DNA-Mapping of CD34+ Cells Purified from Patients with MDS Using High-Resolution SNP Arrays Identifies Significant Regions of Genomic Alterations.

Daniel Nowak, Florian Wagner, Claudia C. Baldus, Olaf Hopfer, Maximilian Mossner, Verena Serbent, Eckhard Thiel, Wolf K. Hofmann

Blood (2006) 108 (11): 2635.

https://doi.org/10.1182/blood.V108.11.2635.2635

Published: 2006

Journal Articles

The Identification of ERG Related Pathways Pinpoints to Mechanisms Implicated in the Inferior Outcome of Acute T-Lymphoblastic Leukemia (T-ALL) with High ERG Expression.

Claudia D. Baldus, MD, Michael D. Radmacher, PhD, Clara D. Bloomfield, MD, Peter Martus, PhD, Stefan Schwartz, MD, Nicola Goekbuget, MD, Dieter Hoelzer, MD, Eckhard Thiel, MD, Wolf K. Hofmann, MD

Blood (2006) 108 (11): 1828.

https://doi.org/10.1182/blood.V108.11.1828.1828

Published: 2006

Journal Articles

Clinical and Immunological Activity of WT1 Peptide Vaccination in Patients with Acute Myeloid Leukemia and Myelodysplasia: Results of a Phase II Trial.

Ulrich Keilholz, MD, Anne Letsch, Antonia Busse, Anne M. Asemissen, Alexander Schmittel, Wolf K. Hofmann, Lutz Uharek, Igor W. Blau, Eckhard Thiel, Carmen Scheibenbogen

Blood (2006) 108 (11): 567.

https://doi.org/10.1182/blood.V108.11.567.567

Published: 2006

Journal Articles

Transcription profiling of C/EBP targets identifies Per2 as a gene implicated in myeloid leukemia

Sigal Gery, Adrian F. Gombart, William S. Yi, Chloe Koeffler, Wolf-K. Hofmann, H. Phillip Koeffler

Blood (2005) 106 (8): 2827–2836.

https://doi.org/10.1182/blood-2005-01-0358

Published: 2005

Includes: Supplemental data

Journal Articles

Antioxidative stress–associated genes in circulating progenitor cells: evidence for enhanced resistance against oxidative stress

Elisabeth Dernbach, Carmen Urbich, Ralf P. Brandes, Wolf K. Hofmann, Andreas M. Zeiher, Stefanie Dimmeler

Blood (2004) 104 (12): 3591–3597.

https://doi.org/10.1182/blood-2003-12-4103

Published: 2004

Journal Articles

C/EBPδ Modulates Cell Growth, Differentiation and Apoptosis of Myeloid Leukemia, Prostate and Breast Cancer Cells.

Sigal Gery, PhD, Sakae Stanosaki, MD, Takayuki Ikezoe, MD, Wolf K. Hofmann, MD, Adrian F. Gombart, PhD, H. Phillip Koeffler, MD

Blood (2004) 104 (11): 4300.

https://doi.org/10.1182/blood.V104.11.4300.4300

Published: 2004

Journal Articles

Rare Mutations of the PIK3CA Gene in Hematologic Malignancies.

Claudia I. Muller, M.D., Carl W. Miller, Ph.D., Wolf-K. Hofmann, M.D., Norihiko Kawamata, M.D., Ph.D., H. Phillip Koeffler, M.D.

Blood (2004) 104 (11): 4350.

https://doi.org/10.1182/blood.V104.11.4350.4350

Published: 2004

Journal Articles

Characterization of gene expression of CD34 + cells from normal and myelodysplastic bone marrow

Wolf-K. Hofmann, Sven de Vos, Martina Komor, Dieter Hoelzer, William Wachsman, H. Phillip Koeffler

Blood (2002) 100 (10): 3553–3560.

https://doi.org/10.1182/blood.V100.10.3553

Published: 2002

Journal Articles

Mutation analysis of transferrin-receptor 2 in patients with atypical hemochromatosis

Wolf-K. Hofmann, Xiang-Jun Tong, Richard S. Ajioka, James P. Kushner, H. Phillip Koeffler

Blood (2002) 100 (3): 1099–1100.

https://doi.org/10.1182/blood-2002-04-1077

Published: 2002

Journal Articles

Expression of C/EBPβ from the C/ebp α gene locus is sufficient for normal hematopoiesis in vivo

Letetia C. Jones, Meng-Liang Lin, Shih-Shun Chen, Utz Krug, Wolf-K. Hofmann, Stephen Lee, Ying-Hue Lee, H. Phillip Koeffler

Blood (2002) 99 (6): 2032–2036.

https://doi.org/10.1182/blood.V99.6.2032

Published: 2002

Journal Articles

Ph + acute lymphoblastic leukemia resistant to the tyrosine kinase inhibitor STI571 has a unique BCR-ABL gene mutation

Wolf-K. Hofmann, Letetia C. Jones, Nathan A. Lemp, Sven de Vos, Harald Gschaidmeier, Dieter Hoelzer, Oliver G. Ottmann, H. Phillip Koeffler

Blood (2002) 99 (5): 1860–1862.

https://doi.org/10.1182/blood.V99.5.1860

Published: 2002

Journal Articles

Mutations in the gene encoding the transcription factor CCAAT/enhancer binding protein α in myelodysplastic syndromes and acute myeloid leukemias

Adrian F. Gombart, Wolf-K. Hofmann, Seiji Kawano, Seisho Takeuchi, Utz Krug, Scott H. Kwok, Renee J. Larsen, Hiroya Asou, Carl W. Miller, Dieter Hoelzer, H. Phillip Koeffler

Blood (2002) 99 (4): 1332–1340.

https://doi.org/10.1182/blood.V99.4.1332

Published: 2002

Journal Articles

Altered apoptosis pathways in mantle cell lymphoma detected by oligonucleotide microarray

Wolf-K. Hofmann, Sven de Vos, Kunihiro Tsukasaki, William Wachsman, Geraldine S. Pinkus, Jonathan W. Said, H. Phillip Koeffler

Blood (2001) 98 (3): 787–794.

https://doi.org/10.1182/blood.V98.3.787

Published: 2001

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Wilms Tumor 1 Gene Mutations in Adult Acute T-Lymphoblastic Leukemia

Identification of ERG Specific Target Genes by Genome-Wide Screening in T-Lymphoblastic Leukemia

Differential Expression of ERG Isoforms in Acute Myeloid and T-Lymphoblastic Leukemia Is Regulated by DNA-Methylation.

Mutations in Specific NOTCH1 Domains Convey a Distinct Phenotype in Adult Acute T-Lymphoblastic Leukemia.

Immunosuppression for Patients with Low and Intermediate Risk Myelodysplastic Syndrome: A Prospective Randomized Multicenter Trial Comparing Antithymocyte Globulin + Cyclosporine with Best Supportive Care: SAKK 33/99.

Low Expression of IL-15 in Adult B-Lineage Acute Lymphoblastic Leukemia Is Associated with Central Nervous System Involvement at Initial Presentation.

Analysis of Immunological and Clinical Response Kinetics to WT1 Peptide Vaccine in Patients with AML and MDS: Need for Supplementation of IWG Response Criteria?.

Detailed Genome-Wide DNA-Mapping of CD34+ Cells Purified from Patients with MDS Using High-Resolution SNP Arrays Identifies Significant Regions of Genomic Alterations.

The Identification of ERG Related Pathways Pinpoints to Mechanisms Implicated in the Inferior Outcome of Acute T-Lymphoblastic Leukemia (T-ALL) with High ERG Expression.

Clinical and Immunological Activity of WT1 Peptide Vaccination in Patients with Acute Myeloid Leukemia and Myelodysplasia: Results of a Phase II Trial.

Transcription profiling of C/EBP targets identifies Per2 as a gene implicated in myeloid leukemia

Antioxidative stress–associated genes in circulating progenitor cells: evidence for enhanced resistance against oxidative stress

C/EBPδ Modulates Cell Growth, Differentiation and Apoptosis of Myeloid Leukemia, Prostate and Breast Cancer Cells.

Rare Mutations of the PIK3CA Gene in Hematologic Malignancies.

Characterization of gene expression of CD34 + cells from normal and myelodysplastic bone marrow

Mutation analysis of transferrin-receptor 2 in patients with atypical hemochromatosis

Expression of C/EBPβ from the C/ebp α gene locus is sufficient for normal hematopoiesis in vivo

Ph + acute lymphoblastic leukemia resistant to the tyrosine kinase inhibitor STI571 has a unique BCR-ABL gene mutation

Mutations in the gene encoding the transcription factor CCAAT/enhancer binding protein α in myelodysplastic syndromes and acute myeloid leukemias

Altered apoptosis pathways in mantle cell lymphoma detected by oligonucleotide microarray

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