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William R. Wilson
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Journal Articles

AKR1C3 is a biomarker of sensitivity to PR-104 in preclinical models of T-cell acute lymphoblastic leukemia

Donya Moradi Manesh, Jad El-Hoss, Kathryn Evans, Jennifer Richmond, Cara E. Toscan, Lauryn S. Bracken, Ashlee Hedrick, Rosemary Sutton, Glenn M. Marshall, William R. Wilson, Raushan T. Kurmasheva, Catherine Billups, Peter J. Houghton, Malcolm A. Smith, Hernan Carol, Richard B. Lock
Journal: Blood
Blood (2015) 126 (10): 1193–1202.
https://doi.org/10.1182/blood-2014-12-618900
Published: 2015
Includes: Supplemental data
Journal Articles

Targeting Hypoxia and AKR1C3 with PR104 in Patients with Acute Leukemia

Juliana M Benito, PhD, Hongbo Lu, William R Wilson, PhD, Teresa J Melink, NP, MSN, Jennie Bretz, Sergej Konoplev, MD, PhD, Elihu H. Estey, MD, Hagop M. Kantarjian, MD, John C Gutheil, MD, Michael Andreeff, MD, PhD, Marina Konopleva, M.D., Ph.D.
Journal: Blood
Blood (2012) 120 (21): 3615.
https://doi.org/10.1182/blood.V120.21.3615.3615
Published: 2012
Journal Articles

Phase I/II Study of PR104, a Bioreductive Prodrug, in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML) Using Patient-Specific Adaptive Dose Selection

Marina Konopleva, M.D., Ph.D., Gautam Borthakur, Peter F Thall, PhD, Andrew Coveler, MD, Farhad Ravandi, MD, Elias Jabbour, Hoang Q Nguyen, PhD, Juliana M Benito, PhD, Yongchuan Gu, PhD, William R Wilson, PhD, Teresa J Melink, NP, MSN, Hagop M. Kantarjian, John C Gutheil, MD, Elihu H Estey, MD
Journal: Blood
Blood (2011) 118 (21): 1523.
https://doi.org/10.1182/blood.V118.21.1523.1523
Published: 2011
Journal Articles

Therapeutic Targeting of the Hypoxic Microenvironment in Acute Lymphocytic Leukemia.

Marina Konopleva, MD, PhD, Juliana Benito, PhD, Yue-Xi Shi, Sergej Konoplev, MD, PhD, Steven M. Kornblau, MD, Olga Frolova, MD, PhD, Patrick A. Zweidler-McKay, MD, PhD, YiHua Qiu, MD, MS, William R. Wilson, PhD, Dario Campana, MD, PhD, Rodrigo Jacamo, PhD, Hongbo Lu, MMSC, Wendy Fang, MD, Gautam Borthakur, MD, Carlos E. Bueso-Ramos, MD, Hagop M. Kantarjian, MD, Deborah A. Thomas, MD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 2040.
https://doi.org/10.1182/blood.V114.22.2040.2040
Published: 2009