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Journal Articles

IL-7 and IL-15 allow the generation of suicide gene–modified alloreactive self-renewing central memory human T lymphocytes

Shin Kaneko, Sara Mastaglio, Attilio Bondanza, Maurilio Ponzoni, Francesca Sanvito, Luca Aldrighetti, Marina Radrizzani, Simona La Seta-Catamancio, Elena Provasi, Anna Mondino, Toshiro Nagasawa, Katharina Fleischhauer, Vincenzo Russo, Catia Traversari, Fabio Ciceri, Claudio Bordignon, Chiara Bonini

Blood (2009) 113 (5): 1006–1015.

https://doi.org/10.1182/blood-2008-05-156059

Published: 2009

Journal Articles

Repression via the GATA box is essential for tissue-specific erythropoietin gene expression

Naoshi Obara, Norio Suzuki, Kibom Kim, Toshiro Nagasawa, Shigehiko Imagawa, Masayuki Yamamoto

Blood (2008) 111 (10): 5223–5232.

https://doi.org/10.1182/blood-2007-10-115857

Published: 2008

Includes: Multimedia, Supplemental data

Journal Articles

Successful Engraftment of Cord Blood Transplantation Following Reduced-Intensity Conditioning Regimen Using Fludarabine and Busulfan for Advanced Hematologic Malignancies.

Yuji Satou, MD, PhD, Toshiro Nagasawa, MD, PhD, Takayuki Azuma, MD, Yuji Miura, MD, Tsunehiko Komatsu, MD, PhD

Blood (2007) 110 (11): 5066.

https://doi.org/10.1182/blood.V110.11.5066.5066

Published: 2007

Journal Articles

A Phase 2 Open-Label, Sequential-Cohort, Dose-Escalation Study of AMG 531 in Japanese Patients with Chronic Immune Thrombocytopenic Purpura (ITP).

Yukari Shirasugi, Kiyoshi Ando, Satoshi Hashino, Toshiro Nagasawa, Yoshiyuki Kurata, Yuji Kishimoto, Koji Iwato, Yusuke Sonehara, Masayuki Ohkura, Tomoko Ohtsu, Janet L. Nichol

Blood (2007) 110 (11): 1308.

https://doi.org/10.1182/blood.V110.11.1308.1308

Published: 2007

Journal Articles

PNH-Affected RBC’s Mean Life Span Estimated by Reticulocyte-Gated Flow Cytometry Reflects In Vivo Hemolysis in PNH.

Haruhiko Ninomiya, MD, Shoko Sato, Yuichi Hasegawa, MD, Hiroshi Kojima, MD, Toshiro Nagasawa, MD

Blood (2007) 110 (11): 3679.

https://doi.org/10.1182/blood.V110.11.3679.3679

Published: 2007

Journal Articles

Transgene Insertion into the Proximity of the c-myb Gene Disrupts Erythroid-Megakaryocytic Lineage Bifurcation.

Harumi Yamamoto Mukai, MD, PhD, Hozumi Motohashi, MD, PhD, Toshiro Nagasawa, MD, PhD, Masayuki Yamamoto, MD, PhD

Blood (2006) 108 (11): 1172.

https://doi.org/10.1182/blood.V108.11.1172.1172

Published: 2006

Journal Articles

GATA-1, Transcriptionally, and Thrombopoietin-Mediated Akt Activation, Post-Translationally, Regulate Continuous Expression of Bcl-xL Protein during Megakaryopoiesis.

Yukinori Kozuma, Hiroshi Kojima, MD, PhD, Satoshi Yuki, Hidenori Suzuki, PhD, Toshiro Nagasawa, MD, PhD

Blood (2006) 108 (11): 1140.

https://doi.org/10.1182/blood.V108.11.1140.1140

Published: 2006

Journal Articles

High Alloreactive Potential of Central Memory T-Lymphocytes Expressing a Suicide Gene for the Cure of Hematologic Malignancies.

Shin Kaneko, MD, PhD, Sara Mastaglio, MD, Attilio Bondanza, MD, Maurilio Ponzoni, MD, Luca Aldrighetti, MD, Salvatore Toma, PhD, Marina Radrizzani, PhD, Simona La Seta Catamancio, PhD, Fabio Ciceri, MD, Toshiro Nagasawa, MD,PhD, Claudio Bordignon, MD,PhD, Chiara Bonini, MD

Blood (2006) 108 (11): 3265.

https://doi.org/10.1182/blood.V108.11.3265.3265

Published: 2006

Journal Articles

Regulation of the Anti-Apoptotic Protein, Bcl-xL, during Differentiation of Megakaryocytes from Stem Cells.

Hiroshi Kojima, MD, PhD, Yukinori Kozuma, Toshiro Nagasawa, MD, PhD

Blood (2005) 106 (11): 3146.

https://doi.org/10.1182/blood.V106.11.3146.3146

Published: 2005

Journal Articles

GATA Motif on the Erythropoietin Gene Promoter Is Essential for Repression of Ectopic Constitutive Erythropoietin Production.

Naoshi Obara, Norio Suzuki, Kim Ki-Bom, Shigehiko Imagawa, Toshiro Nagasawa, Masayuki Yamamoto

Blood (2005) 106 (11): 3139.

https://doi.org/10.1182/blood.V106.11.3139.3139

Published: 2005

Journal Articles

2-Oxoglutarate Down-Regulates Expression of Vascular Endothelial Growth Factor and Erythropoietin through Decreasing Hypoxia Inducible Factor-1 α and Inhibits Angiogenesis.

Shigehiko Imagawa, MD, PhD, Ken Matsumoto, PhD, Naoshi Obara, M.D, Norio Suzuki, PhD, Toshiro Nagasawa, MD, PhD, Masayuki Yamamoto, MD, PhD

Blood (2005) 106 (11): 3957.

https://doi.org/10.1182/blood.V106.11.3957.3957

Published: 2005

Journal Articles

Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease

Yoko Nakano, Shigehiko Imagawa, Ken Matsumoto, Christian Stockmann, Naoshi Obara, Norio Suzuki, Takeshi Doi, Tatsuhiko Kodama, Satoru Takahashi, Toshiro Nagasawa, Masayuki Yamamoto

Blood (2004) 104 (13): 4300–4307.

https://doi.org/10.1182/blood-2004-04-1631

Published: 2004

Journal Articles

Potential Value of N-Desulfated Heparin without Anticoagulant Activity in Treatment of Complement-Mediated Lysis of Paroxysmal Nocturnal Hemoglobinuria Erythrocytes.

Haruhiko Ninomiya, MD, Toshiro Nagasawa, MD

Blood (2004) 104 (11): 2826.

https://doi.org/10.1182/blood.V104.11.2826.2826

Published: 2004

Journal Articles

Initial Laboratory Findings Useful for Predicting the Diagnosis of Chronic ITP: Results of a Multicenter Prospective Study.

Masataka Kuwana, MD, Yoshiyuki Kurata, MD, Kingo Fujimura, MD, Koji Fujisawa, MD, Hideo Wada, MD, Toshiro Nagasawa, MD, Shosaku Nomura, MD, Tetsuhito Kojima, MD, Hideo Yagi, MD, Yasuo Ikeda, MD

Blood (2004) 104 (11): 2061.

https://doi.org/10.1182/blood.V104.11.2061.2061

Published: 2004

Journal Articles

Effect of a single injection of humanized anti-CD154 monoclonal antibody on the platelet-specific autoimmune response in patients with immune thrombocytopenic purpura

Masataka Kuwana, Shosaku Nomura, Kingo Fujimura, Toshiro Nagasawa, Yoshitomo Muto, Yoshiyuki Kurata, Shigeru Tanaka, Yasuo Ikeda

Blood (2004) 103 (4): 1229–1236.

https://doi.org/10.1182/blood-2003-06-2167

Published: 2004

Journal Articles

Levels of vascular endothelial growth factor are elevated in patients with obstructive sleep apnea–hypopnea syndrome

Shigehiko Imagawa, Yuji Yamaguchi, Masato Higuchi, Tomohiro Neichi, Yuichi Hasegawa, Harumi Y. Mukai, Norio Suzuki, Masayuki Yamamoto, Toshiro Nagasawa

Blood (2001) 98 (4): 1255–1257.

https://doi.org/10.1182/blood.V98.4.1255

Published: 2001

Journal Articles

A novel gene, MEL1 , mapped to 1p36.3 is highly homologous to the MDS1/EVI1 gene and is transcriptionally activated in t(1;3)(p36;q21)-positive leukemia cells

Naomi Mochizuki, Seiichi Shimizu, Toshiro Nagasawa, Hideo Tanaka, Masafumi Taniwaki, Jun Yokota, Kazuhiro Morishita

Blood (2000) 96 (9): 3209–3214.

https://doi.org/10.1182/blood.V96.9.3209

Published: 2000

Journal Articles

Contribution of ecto-5′-nucleotidase to the inhibition of platelet aggregation by human endothelial cells

Yasuko Kawashima, Toshiro Nagasawa, Haruhiko Ninomiya

Blood (2000) 96 (6): 2157–2162.

https://doi.org/10.1182/blood.V96.6.2157

Published: 2000

Journal Articles

Role of GATA-1 in Proliferation and Differentiation of Definitive Erythroid and Megakaryocytic Cells In Vivo

Satoru Takahashi, Takuya Komeno, Naruyoshi Suwabe, Keigyo Yoh, Osamu Nakajima, Sigeko Nishimura, Takashi Kuroha, Toshiro Nagasawa, Masayuki Yamamoto

Blood (1998) 92 (2): 434–442.

https://doi.org/10.1182/blood.V92.2.434

Published: 1998

NARROW

IL-7 and IL-15 allow the generation of suicide gene–modified alloreactive self-renewing central memory human T lymphocytes

Repression via the GATA box is essential for tissue-specific erythropoietin gene expression

Successful Engraftment of Cord Blood Transplantation Following Reduced-Intensity Conditioning Regimen Using Fludarabine and Busulfan for Advanced Hematologic Malignancies.

A Phase 2 Open-Label, Sequential-Cohort, Dose-Escalation Study of AMG 531 in Japanese Patients with Chronic Immune Thrombocytopenic Purpura (ITP).

PNH-Affected RBC’s Mean Life Span Estimated by Reticulocyte-Gated Flow Cytometry Reflects In Vivo Hemolysis in PNH.

Transgene Insertion into the Proximity of the c-myb Gene Disrupts Erythroid-Megakaryocytic Lineage Bifurcation.

GATA-1, Transcriptionally, and Thrombopoietin-Mediated Akt Activation, Post-Translationally, Regulate Continuous Expression of Bcl-xL Protein during Megakaryopoiesis.

High Alloreactive Potential of Central Memory T-Lymphocytes Expressing a Suicide Gene for the Cure of Hematologic Malignancies.

Regulation of the Anti-Apoptotic Protein, Bcl-xL, during Differentiation of Megakaryocytes from Stem Cells.

GATA Motif on the Erythropoietin Gene Promoter Is Essential for Repression of Ectopic Constitutive Erythropoietin Production.

2-Oxoglutarate Down-Regulates Expression of Vascular Endothelial Growth Factor and Erythropoietin through Decreasing Hypoxia Inducible Factor-1 α and Inhibits Angiogenesis.

Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease

Potential Value of N-Desulfated Heparin without Anticoagulant Activity in Treatment of Complement-Mediated Lysis of Paroxysmal Nocturnal Hemoglobinuria Erythrocytes.

Initial Laboratory Findings Useful for Predicting the Diagnosis of Chronic ITP: Results of a Multicenter Prospective Study.

Effect of a single injection of humanized anti-CD154 monoclonal antibody on the platelet-specific autoimmune response in patients with immune thrombocytopenic purpura

Levels of vascular endothelial growth factor are elevated in patients with obstructive sleep apnea–hypopnea syndrome

A novel gene, MEL1 , mapped to 1p36.3 is highly homologous to the MDS1/EVI1 gene and is transcriptionally activated in t(1;3)(p36;q21)-positive leukemia cells

Contribution of ecto-5′-nucleotidase to the inhibition of platelet aggregation by human endothelial cells

Role of GATA-1 in Proliferation and Differentiation of Definitive Erythroid and Megakaryocytic Cells In Vivo

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American Society of Hematology

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American Society of Hematology

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