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Journal Articles

Anti Tumor Effect of 2-Oxoglutarate through Inhibition of Angiogenesis in a Murine Tumor Model.

Ken Matsumoto, Naoshi Obara, Masaki Horie, Ayano Naka, Katsunori Utsugi, Shigehiko Imagawa

Blood (2008) 112 (11): 1599.

https://doi.org/10.1182/blood.V112.11.1599.1599

Published: 2008

Journal Articles

Repression via the GATA box is essential for tissue-specific erythropoietin gene expression

Naoshi Obara, Norio Suzuki, Kibom Kim, Toshiro Nagasawa, Shigehiko Imagawa, Masayuki Yamamoto

Blood (2008) 111 (10): 5223–5232.

https://doi.org/10.1182/blood-2007-10-115857

Published: 2008

Includes: Multimedia, Supplemental data

Journal Articles

Detection of Hypoxia-Inducible Gene Manipulation.

Shigehiko Imagawa, MD, PhD, Masaki Horie, Ken Matsumoto, Ikuo Hirano, Norio Suzuki, PhD, Masayuki Yamamoto, MD

Blood (2007) 110 (11): 3662.

https://doi.org/10.1182/blood.V110.11.3662.3662

Published: 2007

Journal Articles

Essential Role and Regulatory Mechanism of the Erythropoietin Gene in the Liver.

Norio Suzuki, PhD, Naoshi Obara, MD, PhD, Ki-bom Kim, Xiaoqing Pan, PhD, Ko-ichi Jishage, PhD, Shigehiko Imagawa, MD, PhD, Masayuki Yamamoto, MD, PhD

Blood (2005) 106 (11): 3138.

https://doi.org/10.1182/blood.V106.11.3138.3138

Published: 2005

Journal Articles

GATA Motif on the Erythropoietin Gene Promoter Is Essential for Repression of Ectopic Constitutive Erythropoietin Production.

Naoshi Obara, Norio Suzuki, Kim Ki-Bom, Shigehiko Imagawa, Toshiro Nagasawa, Masayuki Yamamoto

Blood (2005) 106 (11): 3139.

https://doi.org/10.1182/blood.V106.11.3139.3139

Published: 2005

Journal Articles

2-Oxoglutarate Down-Regulates Expression of Vascular Endothelial Growth Factor and Erythropoietin through Decreasing Hypoxia Inducible Factor-1 α and Inhibits Angiogenesis.

Shigehiko Imagawa, MD, PhD, Ken Matsumoto, PhD, Naoshi Obara, M.D, Norio Suzuki, PhD, Toshiro Nagasawa, MD, PhD, Masayuki Yamamoto, MD, PhD

Blood (2005) 106 (11): 3957.

https://doi.org/10.1182/blood.V106.11.3957.3957

Published: 2005

Journal Articles

Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease

Yoko Nakano, Shigehiko Imagawa, Ken Matsumoto, Christian Stockmann, Naoshi Obara, Norio Suzuki, Takeshi Doi, Tatsuhiko Kodama, Satoru Takahashi, Toshiro Nagasawa, Masayuki Yamamoto

Blood (2004) 104 (13): 4300–4307.

https://doi.org/10.1182/blood-2004-04-1631

Published: 2004

Journal Articles

L-arginine Administration Reverses Anemia of Renal Disease.

Shigehiko Imagawa, M.D., Takahisa Tarumoto, M.D., Makoto Kobayashi, M.D., Keiya Ozawa, M.D.

Blood (2004) 104 (11): 1631.

https://doi.org/10.1182/blood.V104.11.1631.1631

Published: 2004

Journal Articles

Do β -globin , GATA-1 ,or EpoR regulatory domains specifically mark erythroid progenitors in transgenic reporter mice?

Norio Suzuki, Shigehiko Imagawa, Constance T. Noguchi, Masayuki Yamamoto

Blood (2004) 104 (9): 2988–2989.

https://doi.org/10.1182/blood-2004-06-2081

Published: 2004

Journal Articles

Identification and characterization of 2 types of erythroid progenitors that express GATA-1 at distinct levels

Norio Suzuki, Naruyoshi Suwabe, Osamu Ohneda, Naoshi Obara, Shigehiko Imagawa, Xiaoqing Pan, Hozumi Motohashi, Masayuki Yamamoto

Blood (2003) 102 (10): 3575–3583.

https://doi.org/10.1182/blood-2003-04-1154

Published: 2003

Journal Articles

Erythroid-specific expression of the erythropoietin receptor rescued its null mutant mice from lethality

Norio Suzuki, Osamu Ohneda, Satoru Takahashi, Masato Higuchi, Harumi Y. Mukai, Tatsutoshi Nakahata, Shigehiko Imagawa, Masayuki Yamamoto

Blood (2002) 100 (7): 2279–2288.

https://doi.org/10.1182/blood-2002-01-0124

Published: 2002

Journal Articles

Levels of vascular endothelial growth factor are elevated in patients with obstructive sleep apnea–hypopnea syndrome

Shigehiko Imagawa, Yuji Yamaguchi, Masato Higuchi, Tomohiro Neichi, Yuichi Hasegawa, Harumi Y. Mukai, Norio Suzuki, Masayuki Yamamoto, Toshiro Nagasawa

Blood (2001) 98 (4): 1255–1257.

https://doi.org/10.1182/blood.V98.4.1255

Published: 2001

Journal Articles

NG-monomethyl-l-arginine inhibits erythropoietin gene expression by stimulating GATA-2

Takahisa Tarumoto, Shigehiko Imagawa, Ken Ohmine, Tadashi Nagai, Masato Higuchi, Nobuo Imai, Norio Suzuki, Masayuki Yamamoto, Keiya Ozawa

Blood (2000) 96 (5): 1716–1722.

https://doi.org/10.1182/blood.V96.5.1716

Published: 2000

Journal Articles

Negative Regulation of the Erythropoietin Gene Expression by the GATA Transcription Factors

Shigehiko Imagawa, Masayuki Yamamoto, Yasusada Miura

Blood (1997) 89 (4): 1430–1439.

https://doi.org/10.1182/blood.V89.4.1430

Published: 1997

NARROW

Anti Tumor Effect of 2-Oxoglutarate through Inhibition of Angiogenesis in a Murine Tumor Model.

Repression via the GATA box is essential for tissue-specific erythropoietin gene expression

Detection of Hypoxia-Inducible Gene Manipulation.

Essential Role and Regulatory Mechanism of the Erythropoietin Gene in the Liver.

GATA Motif on the Erythropoietin Gene Promoter Is Essential for Repression of Ectopic Constitutive Erythropoietin Production.

2-Oxoglutarate Down-Regulates Expression of Vascular Endothelial Growth Factor and Erythropoietin through Decreasing Hypoxia Inducible Factor-1 α and Inhibits Angiogenesis.

Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease

L-arginine Administration Reverses Anemia of Renal Disease.

Do β -globin , GATA-1 ,or EpoR regulatory domains specifically mark erythroid progenitors in transgenic reporter mice?

Identification and characterization of 2 types of erythroid progenitors that express GATA-1 at distinct levels

Erythroid-specific expression of the erythropoietin receptor rescued its null mutant mice from lethality

Levels of vascular endothelial growth factor are elevated in patients with obstructive sleep apnea–hypopnea syndrome

NG-monomethyl-l-arginine inhibits erythropoietin gene expression by stimulating GATA-2

Negative Regulation of the Erythropoietin Gene Expression by the GATA Transcription Factors

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American Society of Hematology

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American Society of Hematology

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