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Timothy P White
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Journal Articles

Pacritinib Blocks Key Pro-Survival Signaling Related to Mutated MYD88, Produces High Levels of Apoptosis and Overcomes Mutated BTK Cys481 Related BTK-Inhibitor Resistance

Shirong Liu, Amanda Kofides, Xia Liu, Alexa G Canning, Nickolas Tsakmaklis, Maria Luisa Guerrera, Christopher J Patterson, Zachary R Hunter, Kris Richardson, Catherine A. Flynn, Kirsten Meid, Megan Little, Katherine Stockman, Timothy P. White, Shayna R Sarosiek, Jorge J. Castillo, Steven P Treon
Journal: Blood
Blood (2023) 142 (Supplement 1): 3300.
https://doi.org/10.1182/blood-2023-190463
Published: 2023
Journal Articles

Quantitative MYD88 L265P Analysis Represents a Powerful Tool for Assessing Disease Response and Evaluating Clinical Trial Performance in Waldenstrom's Macroglobulinemia

Nickolas Tsakmaklis, Zachary R Hunter, Xia Liu, Amanda Kofides, Shirong Liu, Alexa G Canning, Kris Richardson, Maria Luisa Guerrera, Christopher J Patterson, Kirsten Meid, Timothy P. White, Megan Little, Katherine Stockman, Joshua Gustine, Catherine A. Flynn, Andrew R. Branagan, Shayna R Sarosiek, Jorge J. Castillo, Steven P Treon
Journal: Blood
Blood (2023) 142 (Supplement 1): 211.
https://doi.org/10.1182/blood-2023-190520
Published: 2023
Journal Articles

Ibrutinib and Venetoclax in Symptomatic, Treatment-Naive Patients with Waldenström Macroglobulinemia

Jorge J. Castillo, Shayna R Sarosiek, Andrew R. Branagan, Catherine A. Flynn, Megan Little, Katherine Stockman, Timothy P. White, Alexandra N. Eurell, Maria Luisa Guerrera, Amanda Kofides, Shirong Liu, Xia Liu, Kris Richardson, Nickolas Tsakmaklis, Kirsten Meid, Christopher J Patterson, Zachary R Hunter, Steven P Treon
Journal: Blood
Blood (2023) 142 (Supplement 1): 1661.
https://doi.org/10.1182/blood-2023-174375
Published: 2023
Journal Articles

Prospective Study of Acalabrutinib with Rituximab in Patients with Symptomatic Anti-MAG Mediated IgM Peripheral Neuropathy

Shayna R Sarosiek, Andrew R. Branagan, Christopher Doughty, Catherine A. Flynn, Megan Little, Katherine Stockman, Timothy P. White, Kirsten Meid, Steven P Treon, Jorge J. Castillo
Journal: Blood
Blood (2023) 142 (Supplement 1): 213.
https://doi.org/10.1182/blood-2023-185113
Published: 2023
Journal Articles

Identification of Robust Predictors for Ibrutinib Response By Multi-Omic Genomics in MYD88 Mutated Waldenstrom's Macroglobulinemia

Kris Richardson, Jorge J. Castillo, Shayna Sarosiek, Andrew R. Branagan, Catherine A. Flynn, Kirsten Meid, Carly Leventoff, Timothy P White, Megan Little, Joshua Gustine, Xia Liu, Amanda Kofides, Shirong Liu, Alexa Canning, Julie Wolf, Katherine Kacena, Christopher J Patterson, Maria Luisa Guerrera, Nickolas Tsakmaklis, Steven P Treon, Zachary R Hunter
Journal: Blood
Blood (2022) 140 (Supplement 1): 3541–3542.
https://doi.org/10.1182/blood-2022-170254
Published: 2022
Journal Articles

Ibrutinib and Venetoclax in Previously Untreated Waldenström Macroglobulinemia

Jorge J. Castillo, Shayna Sarosiek, Andrew R. Branagan, David J. Sermer, Catherine A. Flynn, Carly Leventoff, Megan Little, Timothy P White, Kirsten Meid, Alexa Canning, Maria Luisa Guerrera, Amanda Kofides, Xia Liu, Manit Munshi, Nicholas Tsakmaklis, Christopher J Patterson, Zachary R Hunter, Steven P Treon
Journal: Blood
Blood (2022) 140 (Supplement 1): 564–565.
https://doi.org/10.1182/blood-2022-155610
Published: 2022
Journal Articles

Dose Reductions Related to Adverse Effects in Patients with Waldenström Macroglobulinemia Treated with the BTK-Inhibitor Ibrutinib

Shayna Sarosiek, Joshua Gustine, Catherine A Flynn, Carly Leventoff, Timothy P White, Kirsten Meid, Steven P Treon, Jorge J. Castillo
Journal: Blood
Blood (2021) 138 (Supplement 1): 3529.
https://doi.org/10.1182/blood-2021-154284
Published: 2021
Journal Articles

Pirtobrutinib (LOXO-305) Is Active and Overcomes ERK Related Pro-Survival Signaling in Ibrutinib Resistant, BTK Cys481 Mutant Expressing WM and ABC DLBCL Lymphoma Cells Driven By Activating MYD88 Mutations

Manit Munshi, Xia Liu, Amanda Kofides, Nickolas Tsakmaklis, Joshua Gustine, Shayna Sarosiek, Catherine A Flynn, Kirsten Meid, Timothy P White, Carly Leventoff, Christopher J Patterson, Andrew R. Branagan, Prafulla Gokhale, Michael J Poitras, Zachary R Hunter, Maria Luisa Guerrera, Jorge J. Castillo, Guang Yang, Steven P Treon
Journal: Blood
Blood (2021) 138 (Supplement 1): 2261.
https://doi.org/10.1182/blood-2021-153856
Published: 2021
Journal Articles

Phase 1 study of ibrutinib and the CXCR4 antagonist ulocuplumab in CXCR4-mutated Waldenström macroglobulinemia

Clinical Trials & Observations Brief Report
Steven P. Treon, Kirsten Meid, Zachary R. Hunter, Catherine A. Flynn, Shayna R. Sarosiek, Carly R. Leventoff, Timothy P. White, Yang Cao, Aldo M. Roccaro, Antonio Sacco, Maria G. Demos, Maria Luisa Guerrera, Amanda Kofides, Xia Liu, Lian Xu, Christopher J. Patterson, Manit Munshi, Nicholas Tsakmaklis, Guang Yang, Irene M. Ghobrial, Andrew R. Branagan, Jorge J. Castillo
Journal: Blood
Blood (2021) 138 (17): 1535–1539.
https://doi.org/10.1182/blood.2021012953
Published: 2021
Includes: Supplemental data