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Journal Articles

Inhibition of Immune Cell Subsets Is Differentially Affected By Dasatinib Dosage in Patients with Chronic Phase CML

Patrick Harrington, MRCP, FRCPath, Richard Dillon, MA, PhD MRCP, FRCPath, Deepti H. Radia, MRCPI, FRCPath, Donal P. McLornan, MRCP, PhD FRCPath, Philippe Rousselot, MDPhD, Katayoun Rezvani, MD PhD, Shahram Kordasti, MD PhD, Claire Harrison, DM, FRCP, FRCPath, Hugues de Lavallade, MD PhD

Blood (2020) 136 (Supplement 1): 51–53.

https://doi.org/10.1182/blood-2020-139501

Published: 2020

Journal Articles

Immunocluster: A Computational Tool to Explore the Immune Profile and Cellular Heterogeneity of Hematological Diseases Using Liquid and Imaging Mass, and Flow Cytometry Data

Jessica A. Timms, James W Opzoomer, Kevin Blighe, PhD, Benedetta Apollonio, PhD, Thanos Mourikis, Nicolas Chapuis, PharmD, PhD, Richard Bekoe, Alan G. Ramsay, BSc,MSc,PhD, Donal P. McLornan, MRCP, PhD FRCPath, Claire Harrison, DM, FRCP, FRCPath, Paul R. Barber, Peter Parker, Michaela Fontenay, MD PhD, James N. Arnold, Shahram Kordasti, MD PhD

Blood (2020) 136 (Supplement 1): 9–10.

https://doi.org/10.1182/blood-2020-140258

Published: 2020

Journal Articles

Novel Simultaneous Single Cell mRNA and Protein Expression Profiling Identifies Distinct Treg and T Effector Signatures in the Bone Marrow of MDS Patients

Jessica Ann Timms, Susann Winter, Steven Hargreaves, Donal P. McLornan, MB, BCh (Hons), MRCP, PhD FRCPath, Uwe Platzbecker, MD, Shahram Kordasti, MD PhD

Blood (2019) 134 (Supplement_1): 2980.

https://doi.org/10.1182/blood-2019-130355

Published: 2019

Journal Articles

Mechanistic Insights into the Inhibition of T Regulatory Cells By Dasatinib May Predict Immunostimulatory Effects in CML Patients

Patrick Harrington, MRCP, FRCPath, Richard Dillon, MA, PhD MRCP, FRCPath, Philippe Rousselot, MD PhD, Deepti Radia, Yvonne Francis, Claire N Harrison, Professor, Shahram Kordasti, MD PhD, Hugues De Lavallade

Blood (2019) 134 (Supplement_1): 1635.

https://doi.org/10.1182/blood-2019-129135

Published: 2019

Journal Articles

Attenuated Immune Responses to the Annual Influenza A Vaccine in Patients with Myeloproliferative Neoplasms

Samah Alimam, FRCPath, Jessica Ann Timms, Richard Dillon, MA, PhD MRCP, FRCPath, Tracey Mare, Deepti Radia, Hugues De Lavallade, Claire N Harrison, Professor, Shahram Kordasti, MD PhD, Donal P. McLornan, MB, BCh (Hons), MRCP, PhD FRCPath

Blood (2019) 134 (Supplement_1): 1673.

https://doi.org/10.1182/blood-2019-129091

Published: 2019

Journal Articles

Machine Learning Approach Identifies Independent Prognostic Value of Flow Cytometry (FCM) in Myelodysplastic Syndromes (MDS)

Uta Oelschlaegel, PhD, Kevin Blighe, PhD, Susann Winter, PhD, Katja Sockel, MD, Martin Bornhäuser, MD, Shahram Kordasti, MD PhD, Uwe Platzbecker

Blood (2019) 134 (Supplement_1): 4251.

https://doi.org/10.1182/blood-2019-128042

Published: 2019

Journal Articles

Functional Characteristics of FAS-L Resistant and IL-2 Deprived Regulatory T Cells (Treg A) in Idiopathic Aplastic Anaemia

Benedetta Costantini, MD, Syed A Mian, PhD, Shok Ping Lim, PhD, Frederic Toulza, PhD, Stephen Orr, PhD, Pilar Perez-Abellan, MSc, Ander Abarrategi, PhD, Farzin Farzaneh, PhD, Dominique Bonnet, PhD, Judith Marsh, MD, Shahram Kordasti, MD PhD, Ghulam Mufti, DM, FRCP, FRCPath

Blood (2017) 130 (Supplement 1): 2450.

https://doi.org/10.1182/blood.V130.Suppl_1.2450.2450

Published: 2017

Journal Articles

Neoantigens in MDS Are Associated with Two Novel CD4+ T Cell Subsets and Improved Overall Survival

Thomas Coats, MD, Alexander E Smith, PhD, Athanasios Mourikis, Tala Shahin, Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath, Steve Best, PhD, Sneha Chitre, Richard Ellis, Nedyalko Petrov, Susanne Heck, Jonathan Michael Irish, PhD, Shahram Kordasti, MD PhD, Ghulam Mufti, DM, FRCP, FRCPath

Blood (2017) 130 (Supplement 1): 2958.

https://doi.org/10.1182/blood.V130.Suppl_1.2958.2958

Published: 2017

Journal Articles

Mass Cytometry Reveals PD1 Upregulation Is an Early Step in MDS Disease Progression

Thomas Coats, MD, Alexander e Smith, PhD, Thanos P Mourikis, Jonathan Michael Irish, PhD, Shahram Kordasti, MD PhD, Ghulam J Mufti, MD

Blood (2016) 128 (22): 4296.

https://doi.org/10.1182/blood.V128.22.4296.4296

Published: 2016

Journal Articles

CD141 Expressing Monocytes Show an Inflammatory Profile and Are Associated with Low-Risk Features in Myelodysplastic Syndromes

Nathalie van Leeuwen-Kerkhoff, MD, Theresia M. Westers, PhD, Shahram Kordasti, MD PhD, Tanja D. de Gruijl, PhD, Arjan A. van de Loosdrecht, MD PhD

Blood (2016) 128 (22): 4298.

https://doi.org/10.1182/blood.V128.22.4298.4298

Published: 2016

Journal Articles

Towards the Potential Use of In Vitro Expanded Regulatory T-Cells (Tregs) in Aplastic Anemia (AA): Opportunities for Therapy

Benedetta Costantini, MD MPhil, Shahram Kordasti, MD PhD, Marc Martinez-Llordella, PhD, Giovanni Povoleri, MPhil, Judith C. W. Marsh, MD FRCP, FRCPath, Frederic Toulza, PhD, Ghulam J. Mufti, DM, FRCP, FRCPath

Blood (2016) 128 (22): 2673.

https://doi.org/10.1182/blood.V128.22.2673.2673

Published: 2016

Journal Articles

Autologous Ex-Vivo Regulatory T Cells(Tregs) Expansion in Aplastic Anemia for Potential Clinical Use

Benedetta Costantini, MD, Shahram Kordasti, MD PhD, Seidl Thomas, Smith Alexander, PhD, Mian Syed, PhD, Aytug Kizilors, PhD, Martinez-Llordella Marc, PhD, Judith C Marsh, MD, Ghulam J. Mufti, MD PhD

Blood (2015) 126 (23): 3617.

https://doi.org/10.1182/blood.V126.23.3617.3617

Published: 2015

Journal Articles

Dendritic Cell Subsets in Bone Marrow and Peripheral Blood of Patients with Myelodysplastic Syndromes Display Numeric and Functional Defects

Nathalie van Leeuwen-Kerkhoff, MD, Theresia M. Westers, PhD, Hetty J Bontkes, PhD, Shahram Kordasti, MD PhD, Ghulam J. Mufti, MD PhD, Tanja D de Gruijl, PhD, Arjan A van de Loosdrecht, MD PhD

Blood (2015) 126 (23): 4109.

https://doi.org/10.1182/blood.V126.23.4109.4109

Published: 2015

Journal Articles

NLRP3 Inflammosome Polymorphisms Are Enriched in Myelodysplastic Syndrome Patients with Autoimmune Disorders

Syed A Mian, BSc, M.Phil, Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath, Aytug Kizilors, PhD, Kathy L McGraw, PhD, Shahram Kordasti, MD PhD, Stephan Menzel, PhD, Alexander e Smith, PhD, Pilar Perezabellan, BSc, David Sallman, MD, Alan F. List, MD, Ghulam J Mufti, FRCP, FRCPath

Blood (2015) 126 (23): 1659.

https://doi.org/10.1182/blood.V126.23.1659.1659

Published: 2015

Journal Articles

High Resolution Mass Cytometry (CyTOF) in Aplastic Anaemia (AA) Can Identify an Aberrant Treg Subset with Pro-Inflammatory Properties, Predicting Poor Response to Immunosuppressive Therapy

Shahram Kordasti, MD PhD, Thomas Seidl, Richard J Ellis, PhD, Austin Kulasekararaj, Xingmin Feng, PhD, Danielle M. Townsley, MD MSc, Susanne Heck, PhD, Neal S. Young, MD, Judith C Marsh, MD, Ghulam J. Mufti, DM, FRCP, FRCPath

Blood (2014) 124 (21): 1600.

https://doi.org/10.1182/blood.V124.21.1600.1600

Published: 2014

Journal Articles

Myeloid Derived Suppressor Cell Expansion Correlates With Increased regulatory T Cells In Myelodysplastic Syndrome

Astrid Olsnes Kittang, MD, PhD, Shahram Kordasti, MD, PhD, Kristoffer Evebø Sand, MD, Pilar Perezabellan, Thomas Seidl, Kristin Paulsen Rye, Karen Marie Hagen, Geir Hallan, MD, PhD, Austin G Kulasekararaj, MD, PhD, Øystein Bruserud, MD, PhD, Ghulam J. Mufti, MD, PhD

Blood (2013) 122 (21): 2766.

https://doi.org/10.1182/blood.V122.21.2766.2766

Published: 2013

Journal Articles

Reduction of Tregs with Expansion of Th1 Cells and Lack of IFN-γ Secretion by GPI Negative T-Cells In PNH

Shahram Kordasti, MD, PhD, Modupe Elebute, MBBS, MD, MRCP, FRCPath, Pilar Perez Abellan, Austin G Kulasekararaj, Janet Hayden, Azim Mohamedali, PHD, Ghulam J. Mufti, DM, FRCP, FRCPath

Blood (2010) 116 (21): 2240.

https://doi.org/10.1182/blood.V116.21.2240.2240

Published: 2010

Journal Articles

Dysfunctional Tregs with Absence of Cytokine-Secreting CD4 + T-Cell Subsets and Marked Expansion of Th1 Cells Is a Hallmark of Idiopathic Aplastic Anaemia (AA)

Shahram Kordasti, MD, PhD, Judith C. W. Marsh, MD, Pilar Perez Abellan, Sufyan Alkhan, Janet Hayden, Caroline Veen, Jie Jiang, Farzin Farzaneh, DPhil, Ghulam J. Mufti, DM, FRCP, FRCPath

Blood (2010) 116 (21): 2233.

https://doi.org/10.1182/blood.V116.21.2233.2233

Published: 2010

Journal Articles

Cytokine Profile of Patients with Invasive Apsergillosis- Preliminary Results.

M. Mansour Ceesay, MRCP, FRCPath, Shahram Kordasti, MD, PhD, Lisa Berry, Melvyn Smith, PhD, Jim Wade, FRCPath, Ghulam J. Mufti, DM, FRCP, FRCPath, Antonio Pagliuca, MBBS, FRCP, FRCPath, MA

Blood (2010) 116 (21): 1500.

https://doi.org/10.1182/blood.V116.21.1500.1500

Published: 2010

NARROW

Inhibition of Immune Cell Subsets Is Differentially Affected By Dasatinib Dosage in Patients with Chronic Phase CML

Immunocluster: A Computational Tool to Explore the Immune Profile and Cellular Heterogeneity of Hematological Diseases Using Liquid and Imaging Mass, and Flow Cytometry Data

Novel Simultaneous Single Cell mRNA and Protein Expression Profiling Identifies Distinct Treg and T Effector Signatures in the Bone Marrow of MDS Patients

Mechanistic Insights into the Inhibition of T Regulatory Cells By Dasatinib May Predict Immunostimulatory Effects in CML Patients

Attenuated Immune Responses to the Annual Influenza A Vaccine in Patients with Myeloproliferative Neoplasms

Machine Learning Approach Identifies Independent Prognostic Value of Flow Cytometry (FCM) in Myelodysplastic Syndromes (MDS)

Functional Characteristics of FAS-L Resistant and IL-2 Deprived Regulatory T Cells (Treg A) in Idiopathic Aplastic Anaemia

Neoantigens in MDS Are Associated with Two Novel CD4+ T Cell Subsets and Improved Overall Survival

Mass Cytometry Reveals PD1 Upregulation Is an Early Step in MDS Disease Progression

CD141 Expressing Monocytes Show an Inflammatory Profile and Are Associated with Low-Risk Features in Myelodysplastic Syndromes

Towards the Potential Use of In Vitro Expanded Regulatory T-Cells (Tregs) in Aplastic Anemia (AA): Opportunities for Therapy

Autologous Ex-Vivo Regulatory T Cells(Tregs) Expansion in Aplastic Anemia for Potential Clinical Use

Dendritic Cell Subsets in Bone Marrow and Peripheral Blood of Patients with Myelodysplastic Syndromes Display Numeric and Functional Defects

NLRP3 Inflammosome Polymorphisms Are Enriched in Myelodysplastic Syndrome Patients with Autoimmune Disorders

High Resolution Mass Cytometry (CyTOF) in Aplastic Anaemia (AA) Can Identify an Aberrant Treg Subset with Pro-Inflammatory Properties, Predicting Poor Response to Immunosuppressive Therapy

Myeloid Derived Suppressor Cell Expansion Correlates With Increased regulatory T Cells In Myelodysplastic Syndrome

Reduction of Tregs with Expansion of Th1 Cells and Lack of IFN-γ Secretion by GPI Negative T-Cells In PNH

Dysfunctional Tregs with Absence of Cytokine-Secreting CD4 + T-Cell Subsets and Marked Expansion of Th1 Cells Is a Hallmark of Idiopathic Aplastic Anaemia (AA)

Cytokine Profile of Patients with Invasive Apsergillosis- Preliminary Results.

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American Society of Hematology

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American Society of Hematology

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