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Saurabh Kumar
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Journal Articles

A genome-wide CRISPR screen identifies conventional and novel ferroptosis regulators in Acute Myeloid Leukemia

Free
Liang Zhang, Ran Zhao, Kazuharu Kamachi, Saurabh Kumar Gupta, Hiroki Akiyama, Michael Andreeff, Jo Ishizawa
Journal: Blood
Blood (2025) 146 (Supplement 1): 5057.
https://doi.org/10.1182/blood-2025-5057
Published: 2025
Journal Articles

Inhibition of Drp1, a mitochondrial fission GTPase disrupts mitochondrial quality control and impairs stem-like properties in Acute Myeloid Leukemia

Free
Priyanka Sharma, Saurabh Kumar Gupta, Anudishi Tyagi, Abdullah Khasawneh, Hiroki Akiyama, M. Anna Zal, Bing Carter, Michael Andreeff, Yoko Tabe, Gautam Borthakur
Journal: Blood
Blood (2025) 146 (Supplement 1): 5055.
https://doi.org/10.1182/blood-2025-5055
Published: 2025
Journal Articles

Unidirectional synergy between ferroptosis and apoptosis reveals a novel therapeutic strategy for refractory AML

Free
Kazuharu Kamachi, Hiroki Akiyama, Ran Zhao, Liang Zhang, Saurabh Kumar Gupta, Lauren Ostermann, Po Yee Mak, Yuji Otsuki, Osamu Nagano, Hideyuki Saya, Ayumu Taguchi, Natthakan Thongon, Simona Colla, Guillermo Garcia-Manero, Dong Shuxin, Alessia Lodi, Bing Carter, Steven Kornblau, Michael Andreeff, Jo Ishizawa
Journal: Blood
Blood (2025) 146 (Supplement 1): 5050.
https://doi.org/10.1182/blood-2025-5050
Published: 2025
Journal Articles

Engineered platelets as immune modulators: A novel strategy to prevent FVIII inhibitor formation in hemophilia A

Free
Yingyu Chen, Feng Xue, Saurabh Kumar, Jocelyn Schroeder, Qizhen Shi
Journal: Blood
Blood (2025) 146 (Supplement 1): 3054.
https://doi.org/10.1182/blood-2025-3054
Published: 2025
Journal Articles

Ferroptosis activates NK and CAR T cell-mediated anti-tumor immunity in Acute Myeloid Leukemia

Free
Saurabh Kumar Gupta, Kazuharu Kamachi, Liang Zhang, Ran Zhao, Babita Kaundal, Jiangxing LV, Li Li, Venkata Lokesh Battula, Xufeng Chen, Hussein Abbas, Michael Andreeff, Jo Ishizawa
Journal: Blood
Blood (2025) 146 (Supplement 1): 1496.
https://doi.org/10.1182/blood-2025-1496
Published: 2025
Journal Articles

The T follicular helper/T follicular helper regulatory pathway in FVIII immune responses in mice

Available to Purchase
Weiqing Jing, Jocelyn A. Schroeder, Saurabh Kumar, Juan Chen, Yuanhua Cai, Lynn M. Malec, Alexander L. Dent, Weiguo Cui, Qizhen Shi
Journal: Blood
Blood (2025) 146 (8): 998–1010.
https://doi.org/10.1182/blood.2025029470
Published: 2025
Includes: Supplemental data
Journal Articles

Isolation of Lipid Droplets from Acute Myeloid Leukemia Cells for Lipidomic Analysis

Free
Ran Zhao, Liang Zhang, Kazuharu Kamachi, Saurabh Kumar Gupta, Hiroki Akiyama, Jalen Nguyen, Michael Andreeff, Jo Ishizawa, Alessia Lodi
Journal: Blood
Blood (2024) 144 (Supplement 1): 7502.
https://doi.org/10.1182/blood-2024-201676
Published: 2024
Journal Articles

Molecular Interactions between Mitochondrial Ferroptosis and Apoptosis Pathways in Acute Myeloid Leukemia

Free
Kazuharu Kamachi, Hiroki Akiyama, Ran Zhao, Liang Zhang, Saurabh Kumar Gupta, Lauren B. Ostermann, Yuji Otsuki, Osamu Nagano, Hideyuki Saya, Ayumu Taguchi, Michael Andreeff, Jo Ishizawa
Journal: Blood
Blood (2024) 144 (Supplement 1): 2765.
https://doi.org/10.1182/blood-2024-201661
Published: 2024
Journal Articles

Targeting Lipid Droplet Biogenesis to Enhance Ferroptosis in Acute Myeloid Leukemia

Free
Liang Zhang, Ran Zhao, Hiroki Akiyama, Jalen Nguyen, Kazuharu Kamachi, Saurabh Kumar Gupta, Valeria Impedovo, G. Lavender Hackman, Michael Andreeff, Alessia Lodi, Jo Ishizawa
Journal: Blood
Blood (2024) 144 (Supplement 1): 1400.
https://doi.org/10.1182/blood-2024-208616
Published: 2024
Journal Articles

The Tfh/Tfr Pathway Is Pivotal in FVIII Inhibitor Development in Mice

Free
Weiqing Jing, Jocelyn Schroeder, Juan Chen, Yuanhua Cai, Saurabh Kumar, Alexander Dent, Qizhen Shi
Journal: Blood
Blood (2023) 142 (Supplement 1): 3971.
https://doi.org/10.1182/blood-2023-180998
Published: 2023
Journal Articles

Withaferin-a Alleviates Acute Graft Versus Host Disease By Regulating Immune Cell Proliferation, Differentiation and Cytokine Storm Via Inhibition of JAK2-STAT3 Signalling

Free
Vikram Gota, Saurabh Kumar Gupta, Deepshikha Dutta, Kajal Dalvi, Twinkle Khanka, Akanksha Chichra, Sachin Punatar, Anant Gokarn, Sumeet Prakash Mirgh, Nishant Jindal, Prashant R. Tembhare, Syed K Khizer Hasan, Lal Hingorani, Navin Khattry
Journal: Blood
Blood (2022) 140 (Supplement 1): 12669–12670.
https://doi.org/10.1182/blood-2022-164545
Published: 2022
Journal Articles

Receptor-binding residues lie in central regions of Duffy-binding–like domains involved in red cell invasion and cytoadherence by malaria parasites

Free
Alfredo Mayor, Nivedita Bir, Ritica Sawhney, Shailja Singh, Priyabrata Pattnaik, Saurabh Kumar Singh, Amit Sharma, Chetan E. Chitnis
Journal: Blood
Blood (2005) 105 (6): 2557–2563.
https://doi.org/10.1182/blood-2004-05-1722
Published: 2005