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Journal Articles

Preclinical Data In Cynomolgus (cyn) Monkeys Of ASTX727, a Novel Oral Hypomethylating Agent (HMA) Composed Of Low-Dose Oral Decitabine Combined With a Novel Cytidine Deaminase Inhibitor (CDAi) E7727

Aram Oganesian, PhD, Sanjeev Redkar, PhD, Pietro Taverna, PhD, Rajashree Joshi-Hangal, PhD, Mohammad Azab, MD
Journal: Blood
Blood (2013) 122 (21): 2526.
https://doi.org/10.1182/blood.V122.21.2526.2526
Published: 2013
Journal Articles

Mechanisms of cytotoxicity to Pim kinase inhibitor, SGI-1776, in acute myeloid leukemia

Lisa S. Chen, Sanjeev Redkar, Pietro Taverna, Jorge E. Cortes, Varsha Gandhi
Journal: Blood
Blood (2011) 118 (3): 693–702.
https://doi.org/10.1182/blood-2010-12-323022
Published: 2011
Includes: Supplemental data
Journal Articles

SGI-110, a Novel Second Generation Potent DNA Methylation Inhibitor, In Development for the Treatment of MDS and AML. Preclinical Safety, Pharmacokinetics, and DNA Methylation Results of a Low Volume Subcutaneous (SC) Formulation

Jason Scholl, PhD, Rajashree Joshi-Hangal, PhD, Roger Inloes, PhD, Chongtie Shi, PhD, Pietro Taverna, PhD, Gavin S. Choy, PharmD, MBA, Sanjeev Redkar, PhD, Mohammad Azab, MD, MSC, MBA
Journal: Blood
Blood (2010) 116 (21): 1872.
https://doi.org/10.1182/blood.V116.21.1872.1872
Published: 2010
Journal Articles

Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia cells

Lisa S. Chen, Sanjeev Redkar, David Bearss, William G. Wierda, Varsha Gandhi
Journal: Blood
Blood (2009) 114 (19): 4150–4157.
https://doi.org/10.1182/blood-2009-03-212852
Published: 2009
Includes: Supplemental data
Journal Articles

Pim Kinase Inhibitor, SGI-1776, Induces Apoptosis in CLL Lymphocytes

Lisa S Chen, Ph.D, William G Wierda, M.D., Ph.D, Sanjeev Redkar, Ph.D, David J. Bearss, PhD, Varsha Gandhi, Ph.D
Journal: Blood
Blood (2008) 112 (11): 4199.
https://doi.org/10.1182/blood.V112.11.4199.4199
Published: 2008
Journal Articles

Anti-AML Activity of Combined Epigenetic Therapy with Novel DNMT1 Inhibitors SGI-110 or SGI-1036 and Histone Deacetylase Inhibitor Panobinostat.

Warren Fiskus, Pace Johnston, Rajeshree Joshi, Rekha Rao, Celalettin Ustun, Anand Jillella, Peter Atadja, Stuart Hwang, Sanjeev Redkar, Kapil N. Bhalla
Journal: Blood
Blood (2008) 112 (11): 3355.
https://doi.org/10.1182/blood.V112.11.3355.3355
Published: 2008
Journal Articles

Fetal Hemoglobin Induction in Baboons (P. Anubis) Following Admistration of a Novel Decitabine Dinucleotide (S110) Compound.

Donald Lavelle, PhD, Kestis Vaitkus, B.S., Virryan Banzon, M.S., Maria Hankewych, B.S., Pasit Phiasivongsva, Ph.D., Sanjeev Redkar, Ph.D., Sarath Kanekal, Ph.D., David Bearss, Ph.D., Chongtie Shi, Ph.D., Roger Inloes, Ph.D., Joseph DeSimone, Ph.D.
Journal: Blood
Blood (2007) 110 (11): 571.
https://doi.org/10.1182/blood.V110.11.571.571
Published: 2007
Journal Articles

Oral Administration of Dacogen Mesylate Increases HbF and Decreases DNA Methylation of the ε- and γ-Globin Genes in Anemic Baboons ( Papio anubis ).

Donald Lavelle, PhD, Kestis Vaitkus, DVM, Janet Chin, MD, Sanjeev Redkar, PhD, Pasit Phiasivongsa, PhD, Maria Hankewych, BS, Joseph DeSimone, PhD
Journal: Blood
Blood (2005) 106 (11): 3645.
https://doi.org/10.1182/blood.V106.11.3645.3645
Published: 2005