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Journal Articles

Engineering Resistance to Antigen-Specific Immunotherapy in Normal Hematopoietic Stem Cells By Gene Editing to Enable Targeting of Acute Myeloid Leukemia

Miriam Y Kim, MD, Saad S Kenderian, MD, Daniel Schreeder, MD PhD, Michael Klichinsky, PharmD, Miroslaw Kozlowski, PhD, Olga Shestova, PhD, Marco Ruella, MD, Saar I Gill, MBBS, PhD

Blood (2016) 128 (22): 1000.

https://doi.org/10.1182/blood.V128.22.1000.1000

Published: 2016

Journal Articles

Allogeneic Stem Cell Transplantation in Patients ≥70 Years Old

Christopher C Walling, BS, Pamela A Shaw, PhD, Noelle V Frey, MD, Saar I Gill, MBBS, PhD, Elizabeth O. Hexner, MD, Alison W Loren, MD MS, Selina Luger, MD, James K Mangan, MD PhD, Mary Ellen Martin, MD, Jacqueline Smith, CRNP, Edward A. Stadtmauer, MD, David L. Porter, MD

Blood (2016) 128 (22): 2309.

https://doi.org/10.1182/blood.V128.22.2309.2309

Published: 2016

Journal Articles

Oral Vancomycin Is Highly Effective in Preventing Clostridium Difficile infection in Allogeneic Hematopoietic Stem Cell Transplant Recipients

Alex Ganetsky, PharmD, BCOP, Jennifer H Han, MD MSCE, Mitchell E Hughes, PharmD, Daria V. Babushok, MD PhD, Noelle V Frey, MD, Saar I Gill, MBBS, PhD, Elizabeth Hexner, MD, Alison Wakoff Loren, MD MS, Selina Luger, MD, James K Mangan, MD PhD, Jacqueline Smith, CRNP, Edward A. Stadtmauer, MD, Craig W. Freyer, PharmD, BCOP, Cheryl Gilmar, MT, David L Porter, MD

Blood (2016) 128 (22): 2225.

https://doi.org/10.1182/blood.V128.22.2225.2225

Published: 2016

Journal Articles

Kinase Inhibitor Ibrutinib Prevents Cytokine-Release Syndrome after Anti-CD19 Chimeric Antigen Receptor T Cells (CART) for B Cell Neoplasms

Marco Ruella, MD, Saad S Kenderian, MD, Olga Shestova, PhD, Michael Klichinsky, PharmD, J. Joseph Melenhorst, PhD, Mariusz A Wasik, MD, Simon F. Lacey, PhD, Carl H June, MD, Saar I Gill, MBBS, PhD

Blood (2016) 128 (22): 2159.

https://doi.org/10.1182/blood.V128.22.2159.2159

Published: 2016

Journal Articles

Tocilizumab Is Highly Active for Severe Steroid-Refractory Acute Graft-Versus-Host Disease of the Gastrointestinal Tract

Alex Ganetsky, PharmD, BCOP, Noelle V Frey, MD, Alison W Loren, MD MS, Elizabeth O. Hexner, MD, James K Mangan, MD PhD, Saar I Gill, MBBS, PhD, Selina Luger, MD, Adam D. Cohen, MD, Daria V Babushok, MDPhD, Edward A Stadtmauer, MD, Jacqueline Smith, CRNP, William R. Drobyski, MD, Sarah K Kraus, PharmD, Colleen Timlin, PharmD, BCOP, David L. Porter, MD

Blood (2016) 128 (22): 2245.

https://doi.org/10.1182/blood.V128.22.2245.2245

Published: 2016

Journal Articles

Overcoming the Immunosuppressive Tumor Microenvironment of Hodgkin Lymphoma Using Chimeric Antigen Receptor T Cells

Marco Ruella, MD, Michael Klichinsky, PharmD, Saad S Kenderian, MD, Olga Shestova, PhD, Amy Ziober, Michael D Feldman, MD, Mariusz A Wasik, MD, Carl H June, MD, Saar I Gill, MBBS, PhD

Blood (2016) 128 (22): 43.

https://doi.org/10.1182/blood.V128.22.43.43

Published: 2016

Journal Articles

Identification of PD1 and TIM3 As Checkpoints That Limit Chimeric Antigen Receptor T Cell Efficacy in Leukemia

Saad S Kenderian, MD, Marco Ruella, MD, Olga Shestova, PhD, Michael Klichinsky, PharmD, Miriam Y Kim, MD, David L Porter, MD, Carl H. June, MD, Saar I Gill, MBBS, PhD

Blood (2015) 126 (23): 852.

https://doi.org/10.1182/blood.V126.23.852.852

Published: 2015

Journal Articles

The Addition of the BTK Inhibitor Ibrutinib to Anti-CD19 Chimeric Antigen Receptor T Cells (CART19) Improves Engraftment and Antitumor Responses Against Mantle Cell Lymphoma

Marco Ruella, MD, Saad S Kenderian, MD, Olga Shestova, PhD, Joseph A. Fraietta, PhD, Sohail Qayyum, MD, Qian Zhang, MD PhD, Marcela V. Maus, MDPhD, Xiaobin Liu, PhD, Selene Nunez-Cruz, PhD, Michael Klichinsky, PharmD, Omkar Uday Kawalekar, MS, BS, Michael C. Milone, MD PhD, Simon F. Lacey, PhD BSc, Anthony Mato, MD, Stephen J. Schuster, MD, Michael Kalos, PhD, Carl H. June, MD, Saar I Gill, MBBS, PhD, Mariusz A. Wasik, MD

Blood (2015) 126 (23): 704.

https://doi.org/10.1182/blood.V126.23.704.704

Published: 2015

Journal Articles

Efficient Termination of CD123-Redirected Chimeric Antigen Receptor T Cells for Acute Myeloid Leukemia to Mitigate Toxicity

Sarah K Tasian, MD, Saad S Kenderian, MD, Feng Shen, MDPhD, Yong Li, MDMS, Marco Ruella, MD, William C Fix, BA, Miroslaw Kozlowski, PhD, Martin Carroll, MD, Richard Aplenc, MD PhD, Carl H June, MD, Stephan A Grupp, MD PhD, Saar I Gill, MBBS, PhD

Blood (2015) 126 (23): 565.

https://doi.org/10.1182/blood.V126.23.565.565

Published: 2015

Journal Articles

Combination of Anti-CD123 and Anti-CD19 Chimeric Antigen Receptor T Cells for the Treatment and Prevention of Antigen-Loss Relapses Occurring after CD19-Targeted Immunotherapies

Marco Ruella, MD, David M. Barrett, MD PhD, Saad S Kenderian, MD, Olga Shestova, PhD, Ted J. Hofmann, PhD, John Scholler, Simon F. Lacey, PhD BSc, J. Joseph Melenhorst, PhD, Farzana Nazimuddin, Jessica Perazzelli, PhD, David A Christian, PhD, Christopher A Hunter, PhD, David L Porter, MD, Carl H. June, MD, Stephan A. Grupp, MD PhD, Saar I Gill, MBBS, PhD

Blood (2015) 126 (23): 2523.

https://doi.org/10.1182/blood.V126.23.2523.2523

Published: 2015

Journal Articles

Sustained Functional T Cell Persistence and B Cell Aplasia Following CD19-Targeting Adoptive T Cell Immunotherapy for Relapsed, Refractory CD19+ Malignacy

Michael Kalos, PhD, Bruce L. Levine, PhD, Timothy L Macatee, Irina Kulikovskaya, Erica Suppa, Bipulendu Jena, Saar I. Gill, MBBS, Laurence J N Cooper, MD, PhD, Stephan A. Grupp, MD, PhD, David L Porter, MD, Carl H. June, MD

Blood (2012) 120 (21): 756.

https://doi.org/10.1182/blood.V120.21.756.756

Published: 2012

Journal Articles

Natural Killer Cell Adoptive Immunotherapy Is Hampered by A Rapid Development of NK Cell Dysfunction Characterized by Loss of Effector Mechanisms and Downregulation of the Transcription Factors T-Bet and Eomesodermin; Definition and Possible Mechanism of NK Cell Exhaustion

Saar I. Gill, MBBS, FRACP, Adrianne E Vasey, BS, Jeanette B Baker, PhD, Aaron Smith, BS, Holbrook E Kohrt, MD, Mareike Florek, MD, David Ritchie, MBBS, FRACP, FRCPA, PhD, Robert S Negrin, MD

Blood (2011) 118 (21): 1000.

https://doi.org/10.1182/blood.V118.21.1000.1000

Published: 2011

NARROW

Engineering Resistance to Antigen-Specific Immunotherapy in Normal Hematopoietic Stem Cells By Gene Editing to Enable Targeting of Acute Myeloid Leukemia

Allogeneic Stem Cell Transplantation in Patients ≥70 Years Old

Oral Vancomycin Is Highly Effective in Preventing Clostridium Difficile infection in Allogeneic Hematopoietic Stem Cell Transplant Recipients

Kinase Inhibitor Ibrutinib Prevents Cytokine-Release Syndrome after Anti-CD19 Chimeric Antigen Receptor T Cells (CART) for B Cell Neoplasms

Tocilizumab Is Highly Active for Severe Steroid-Refractory Acute Graft-Versus-Host Disease of the Gastrointestinal Tract

Overcoming the Immunosuppressive Tumor Microenvironment of Hodgkin Lymphoma Using Chimeric Antigen Receptor T Cells

Identification of PD1 and TIM3 As Checkpoints That Limit Chimeric Antigen Receptor T Cell Efficacy in Leukemia

The Addition of the BTK Inhibitor Ibrutinib to Anti-CD19 Chimeric Antigen Receptor T Cells (CART19) Improves Engraftment and Antitumor Responses Against Mantle Cell Lymphoma

Efficient Termination of CD123-Redirected Chimeric Antigen Receptor T Cells for Acute Myeloid Leukemia to Mitigate Toxicity

Combination of Anti-CD123 and Anti-CD19 Chimeric Antigen Receptor T Cells for the Treatment and Prevention of Antigen-Loss Relapses Occurring after CD19-Targeted Immunotherapies

Sustained Functional T Cell Persistence and B Cell Aplasia Following CD19-Targeting Adoptive T Cell Immunotherapy for Relapsed, Refractory CD19+ Malignacy

Natural Killer Cell Adoptive Immunotherapy Is Hampered by A Rapid Development of NK Cell Dysfunction Characterized by Loss of Effector Mechanisms and Downregulation of the Transcription Factors T-Bet and Eomesodermin; Definition and Possible Mechanism of NK Cell Exhaustion

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American Society of Hematology

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ASH Publications

American Society of Hematology

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