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Journal Articles

Efficient and Specific In Vivo Genetic Engineering of Human Hematopoietic Stem Progenitor Cells without Selective Conditioning

Vladimir V Botchkarev, Jr., Sean Harrington, Alexander Justen, Casey Kimber, Anjali Kapuria, Yuanxin Xu, Kelsey Haugh, Ramya Ankala, Nathan Kipniss, Rowena de Jesus, Funmi Adewale, Kathy Daniels, Samantha Crocker, Anna Liang, Shannon Joyce, Derek Smith, Athena Wong, Valeria Berlfein, Shirisha Amatya, Patricia Cruite, Shariq Usmani, Albert Ruzo, Benjamin Ferland, Sundeep Chandra, Matteo Stoppato, Kyle Trudeau, Edward Rebar, Jagesh Shah, Luca Biasco
Journal: Blood
Blood (2023) 142 (Supplement 1): 2252.
https://doi.org/10.1182/blood-2023-181923
Published: 2023
Journal Articles

Efficient and Specific Multi-Locus Editing of Allogeneic CAR T Cells for Hypoimmunity during Large Scale Manufacture Using Cas12b

Christina Chaivorapol, Pascal Beauchesne, Rowena De Jesus, William E Dowdle, Xiaoyu Chen, Alison Bayley, Yunjiang Qiu, Andrew Birnberg, Yu Zheng, Antonino Montalbano, Angela Liu, Misbah Zafar, Karl Manner, Ramya Ankala, Eleonore Tham, Heer Shah, Ben Lam, Jaclyn Lock, Lindong Weng, Kate Watts, Amanda Valdiosera, Kimberly Davis, Lei Wang, Divy Kangeyan, PhD, Nicolas Devos, Athena Wong, Jason Lih, Edward J Rebar
Journal: Blood
Blood (2022) 140 (Supplement 1): 1606–1607.
https://doi.org/10.1182/blood-2022-167627
Published: 2022
Journal Articles

Engineered Hypoimmune CAR T Cells Provide Lasting Tumor Control in Fully Immunocompetent Allogeneic Humanized Mice

Xiaomeng Hu, Pascal Beauchesne, Karl Manner, Corie Gattis, Priscilla Ngo, Rowena De Jesus, Chi Young, Frank Wells, Lindong Weng, Kathy White, William E Dowdle, Aaron Foster, Terry Fry, Sonja Schrepfer
Journal: Blood
Blood (2022) 140 (Supplement 1): 1173–1175.
https://doi.org/10.1182/blood-2022-167943
Published: 2022