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Luca Biasco
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Journal Articles

Efficient and Specific In Vivo Genetic Engineering of Human Hematopoietic Stem Progenitor Cells without Selective Conditioning

Vladimir V Botchkarev, Jr., Sean Harrington, Alexander Justen, Casey Kimber, Anjali Kapuria, Yuanxin Xu, Kelsey Haugh, Ramya Ankala, Nathan Kipniss, Rowena de Jesus, Funmi Adewale, Kathy Daniels, Samantha Crocker, Anna Liang, Shannon Joyce, Derek Smith, Athena Wong, Valeria Berlfein, Shirisha Amatya, Patricia Cruite, Shariq Usmani, Albert Ruzo, Benjamin Ferland, Sundeep Chandra, Matteo Stoppato, Kyle Trudeau, Edward Rebar, Jagesh Shah, Luca Biasco
Journal: Blood
Blood (2023) 142 (Supplement 1): 2252.
https://doi.org/10.1182/blood-2023-181923
Published: 2023
Journal Articles

A Comprehensive High Resolution Scrna-Seq Analytical Platform for Characterizing Human Hematopoietic Stem/Progenitor Cells States in Ex Vivo Drug Products

Cristina Baricordi, PhD, Mariana Loperfido, PhD, Aimin Yan, PhD, Luigi Barbarossa, Mercedes Segura, PhD, Azadeh Golipour, PhD, Chris Mason, PhD MD, Luca Biasco, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 28–29.
https://doi.org/10.1182/blood-2020-141057
Published: 2020
Journal Articles

Bipotent Lymphoid Progenitors Independently Maintain Long-Term Genetically Engineered T and NK Cell Production in Humans

Natalia Izotova, Christine Rivat, Cristina Baricordi, PhD, Elena Blanco-Alvarez, Danilo Pellin, Eleanor Watt, Soragia Athina Gkazi, PhD, Stuart Adams, PhD, Kimberly Gilmour, Jinhua Xu Bayford, Claire Booth, MBBS, PhD MSc, Bobby H Gaspar, MBBS, PhD BS, Adrian J. Thrasher, MBBS, PhD FMedSci, Luca Biasco, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 50.
https://doi.org/10.1182/blood-2020-137001
Published: 2020
Journal Articles

Clonal Dynamics of Early Responder and Long-Term Surviving CAR-T Cells in Humans

Christine Rivat, Natalia Izotova, Rachel Richardson, MSc, Danilo Pellin, Rachael Hough, Robert Wynn, MD, Kim Champion, Andre Lopes, Sara Ghorashian, FRCPath, PhD, Martin Pule, Adrian J. Thrasher, MBBS, PhD FMedSci, Luca Biasco, PhD, Persis J Amrolia, FRCP, FRCPath, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 52.
https://doi.org/10.1182/blood-2019-125916
Published: 2019
Journal Articles

Highly Efficient Therapeutic Gene Editing of BCL11A enhancer in Human Hematopoietic Stem Cells from ß-Hemoglobinopathy Patients for Fetal Hemoglobin Induction

Jing Zeng, MD, Daniel E. Bauer, MD PhD, Yuxuan Wu, PhD, Benjamin P Roscoe, Pengpeng Liu, Qiuming Yao, PhD, Cicera Lazzarrotto, M. Kendell Clement, Mitchel A. Cole, BS, Kevin Luk, Cristina Baricordi, Erica B. Esrick, MD, John P Manis, MD, David Dorfma, David A. Williams, MD, Alessandra Biffi, MD PhD, Carlo Brugnara, MD, Luca Biasco, Christian Brendel, PhD, Luca Pinello, PhD, Shengdar Tsai, PhD, Scot A. Wolfe
Journal: Blood
Blood (2018) 132 (Supplement 1): 3482.
https://doi.org/10.1182/blood-2018-99-119365
Published: 2018
Journal Articles

The Single-Cell Transcriptional Landscape of Human Hematopoietic Progenitors

Mariana Loperfido, PhD, Danilo Pellin, Cristina Baricordi, Samuel Louis Wolock, Allon Moshe Klein, Luca Biasco
Journal: Blood
Blood (2018) 132 (Supplement 1): 1266.
https://doi.org/10.1182/blood-2018-99-116327
Published: 2018
Journal Articles

Safety and Clinical Benefit of Lentiviral Hematopoietic Stem Cell Gene Therapy for Wiskott-Aldrich Syndrome

Francesca Ferrua, MD, Maria Pia Cicalese, MD PhD, Stefania Galimberti, PhD, Samantha Scaramuzza, PhD, Stefania Giannelli, PhD, Roberta Pajno, MD, Francesca Dionisio, PhD, Luca Biasco, PhD, Maria Carmina Castiello, PhD, Miriam Casiraghi, RN, Marcella Facchini, PhD, Andrea Finocchi, MD, Ayse Metin, MD PhD, Jordan S. Orange, MD PhD, Michael H. Albert, MD, Carmen Petrescu, MD, Marita Bosticardo, PhD, Anna Villa, MD, Chris Dott, PhD, Koen van Rossem, MD MSc, PhD, Maria Grazia Valsecchi, PhD, Fabio Ciceri, MD, Maria Grazia Roncarolo, MD, Luigi Naldini, MD PhD, Alessandro Aiuti, MD PhD
Journal: Blood
Blood (2015) 126 (23): 259.
https://doi.org/10.1182/blood.V126.23.259.259
Published: 2015
Journal Articles

Tracking Genetically Engineered Lymphocytes Long-Term Reveals the Dynamics of T-Cell Immunological Memory

Giacomo Oliveira, PhD, Eliana Ruggiero, PhD, Maria Teresa Lupo Stanghellini, MD, Nicoletta Cieri, MD PhD, Mattia D'Agostino, MD, Raffaele Fronza, PhD, Christina Lulay, Francesca Dionisio, PhD, Sara Mastaglio, MD, Raffaella Greco, MD, Jacopo Peccatori, MD, Alessandro Aiuti, MD, Luca Biasco, PhD, Attilio Bondanza, MD PhD, Antonio Lambiase, MD, Catia Traversari, PhD, Luca Vago, MD PhD, Christof von Kalle, MD, Manfred Schmidt, PhD, Claudio Bordignon, MD, Fabio Ciceri, MD, Chiara Bonini, MD
Journal: Blood
Blood (2015) 126 (23): 263.
https://doi.org/10.1182/blood.V126.23.263.263
Published: 2015
Journal Articles

Long-Term Immunological Profile of Patients Treated with Haploidentical HSCT and TK-Cells to Study the Requirements of Memory T Cell Persistence

Giacomo Oliveira, MSc, Maria Teresa Lupo Stanghellini, MD, Eliana Ruggiero, PhD, Nicoletta Cieri, MD PhD, Mattia D'Agostino, MD, Raffaella Greco, MD, Sara Mastaglio, MD, Maddalena Noviello, PhD, Luca Vago, MD PhD, Luca Biasco, PhD, Attilio Bondanza, MD PhD, Alessandro Aiuti, MD, Antonio Lambiase, MD, Manfred Schmidt, PhD, Catia Traversari, PhD, Christof von Kalle, MD, Fabio Ciceri, MD, Claudio Bordignon, MD, Chiara Bonini, MD
Journal: Blood
Blood (2014) 124 (21): 4793.
https://doi.org/10.1182/blood.V124.21.4793.4793
Published: 2014
Journal Articles

Comprehensive Clonal Mapping of Hematopoiesis in Vivo in Humans By Retroviral Vector Insertional Barcoding

Luca Biasco, PhD, Serena Scala, Francesca Dionisio, Andrea Calabria, Luca Basso Ricci, Samantha Scaramuzza, Cristina Baricordi, Stefania Giannelli, Victor X Neduva, David J Dow, Danilo Pellin, Paola Vicard, Clelia Di Serio, Eugenio Montini, Luigi Naldini, Alessandro Aiuti
Journal: Blood
Blood (2014) 124 (21): 5.
https://doi.org/10.1182/blood.V124.21.5.5
Published: 2014
Journal Articles

In Vivo Tracking of T Cells in Humans Unveils Decade-Long Survival and Activity of Genetically Modified T Memory Stem Cells

Serena Scala, Luca Biasco, PhD, Luca Basso Ricci, Francesca Dionisio, Cristina Baricordi, Andrea Calabria, Stefania Giannelli, Nicoletta Cieri, MD PhD, Federica Barzaghi, Roberta Pajno, Hamoud Al-Mousa, Alessia Scarselli, Caterina Cancrini, Claudio Bordignon, MD, Maria Grazia Roncarolo, MD Prof., Eugenio Montini, Chiara Bonini, MD, Alessandro Aiuti, MD
Journal: Blood
Blood (2014) 124 (21): 547.
https://doi.org/10.1182/blood.V124.21.547.547
Published: 2014
Journal Articles

Uncovering Haematopoietic System Dynamics and Single Multipotent Progenitors Activity In Vivo In Humans by Retroviral Tagging.

Luca Biasco, Cristina Baricordi, Stefania Merella, Cynthia Bartholomae, Alessandro Ambrosi, Danilo Pellin, Clelia Di Serio, Christof Von Kalle, Manfred Schmidt, Alessandro Aiuti
Journal: Blood
Blood (2010) 116 (21): 2611.
https://doi.org/10.1182/blood.V116.21.2611.2611
Published: 2010
Journal Articles

Clonal Analyses of Retroviral Vector Integrations in ADA-SCID Patients Treated with Stem Cell Gene Therapy.

Barbara Cassani, Grazia Andolfi, Massimiliano Mirolo, Luca Biasco, Alessandra Recchia, Fabrizia Urbinati, Cristina Valacca, Samantha Scaramuzza, Matteo Cazzola, Daniela Sartori, Alessandro Ambrosi, Clelia Di Serio, Maria Grazia Roncarolo, Fulvio Mavilio, Claudio Bordignon, Alessandro Aiuti
Journal: Blood
Blood (2006) 108 (11): 3249.
https://doi.org/10.1182/blood.V108.11.3249.3249
Published: 2006
Journal Articles

Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)–deficient mice and corrects their immune and metabolic defects

Alessandra Mortellaro, Raisa Jofra Hernandez, Matteo M. Guerrini, Filippo Carlucci, Antonella Tabucchi, Maurilio Ponzoni, Francesca Sanvito, Claudio Doglioni, Clelia Di Serio, Luca Biasco, Antonia Follenzi, Luigi Naldini, Claudio Bordignon, Maria Grazia Roncarolo, Alessandro Aiuti
Journal: Blood
Blood (2006) 108 (9): 2979–2988.
https://doi.org/10.1182/blood-2006-05-023507
Published: 2006
Includes: Supplemental data