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Filippo Carlucci
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Journal Articles

Update on the safety and efficacy of retroviral gene therapy for immunodeficiency due to adenosine deaminase deficiency

Maria Pia Cicalese, Francesca Ferrua, Laura Castagnaro, Roberta Pajno, Federica Barzaghi, Stefania Giannelli, Francesca Dionisio, Immacolata Brigida, Marco Bonopane, Miriam Casiraghi, Antonella Tabucchi, Filippo Carlucci, Eyal Grunebaum, Mehdi Adeli, Robbert G. Bredius, Jennifer M. Puck, Polina Stepensky, Ilhan Tezcan, Katie Rolfe, Erika De Boever, Rickey R. Reinhardt, Jonathan Appleby, Fabio Ciceri, Maria Grazia Roncarolo, Alessandro Aiuti
Journal: Blood
Blood (2016) 128 (1): 45–54.
https://doi.org/10.1182/blood-2016-01-688226
Published: 2016
Includes: Supplemental data
Journal Articles

Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID

Aisha V. Sauer, Immacolata Brigida, Nicola Carriglio, Raisa Jofra Hernandez, Samantha Scaramuzza, Daniela Clavenna, Francesca Sanvito, Pietro L. Poliani, Nicola Gagliani, Filippo Carlucci, Antonella Tabucchi, Maria Grazia Roncarolo, Elisabetta Traggiai, Anna Villa, Alessandro Aiuti
Journal: Blood
Blood (2012) 119 (6): 1428–1439.
https://doi.org/10.1182/blood-2011-07-366781
Published: 2012
Includes: Supplemental data
Journal Articles

ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency

Aisha V. Sauer, Emanuela Mrak, Raisa Jofra Hernandez, Elena Zacchi, Francesco Cavani, Miriam Casiraghi, Eyal Grunebaum, Chaim M. Roifman, Maria C. Cervi, Alessandro Ambrosi, Filippo Carlucci, Maria Grazia Roncarolo, Anna Villa, Alessandro Rubinacci, Alessandro Aiuti
Journal: Blood
Blood (2009) 114 (15): 3216–3226.
https://doi.org/10.1182/blood-2009-03-209221
Published: 2009
Includes: Supplemental data
Journal Articles

Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients

Barbara Cassani, Massimiliano Mirolo, Federica Cattaneo, Ulrike Benninghoff, Michael Hershfield, Filippo Carlucci, Antonella Tabucchi, Claudio Bordignon, Maria Grazia Roncarolo, Alessandro Aiuti
Journal: Blood
Blood (2008) 111 (8): 4209–4219.
https://doi.org/10.1182/blood-2007-05-092429
Published: 2008
Includes: Supplemental data
Journal Articles

Long-Term Safety and Efficacy of Stem Cell Gene Therapy for ADA-SCID.

Alessandro Aiuti, Ulrike Benninghoff, Barbara Cassani, Federica Cattaneo, Luciano Callegaro, Grazia Andolfi, Massimiliano Mirolo, Samantha Scaramuzza, Sarah Marktel, Antonella Tabucchi, Filippo Carlucci, Martha Eibl, Memet Aker, Shimon Slavin, Fabio Ciceri, Roberto Miniero, Claudio Bordignon, Maria Grazia Roncarolo
Journal: Blood
Blood (2006) 108 (11): 200.
https://doi.org/10.1182/blood.V108.11.200.200
Published: 2006
Journal Articles

Deoxyadenosine Inhibits T-Cell Activation in ADA-SCID Patients through a cAMP/PKA-Dependent Pathway.

Barbara Cassani, Massimiliano Mirolo, Federica Cattaneo, Ulrike Benninghoff, Filippo Carlucci, Antonella Tabucchi, Claudio Bordignon, Maria Grazia Roncarolo, Alessandro Aiuti
Journal: Blood
Blood (2006) 108 (11): 1250.
https://doi.org/10.1182/blood.V108.11.1250.1250
Published: 2006
Journal Articles

Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)–deficient mice and corrects their immune and metabolic defects

Alessandra Mortellaro, Raisa Jofra Hernandez, Matteo M. Guerrini, Filippo Carlucci, Antonella Tabucchi, Maurilio Ponzoni, Francesca Sanvito, Claudio Doglioni, Clelia Di Serio, Luca Biasco, Antonia Follenzi, Luigi Naldini, Claudio Bordignon, Maria Grazia Roncarolo, Alessandro Aiuti
Journal: Blood
Blood (2006) 108 (9): 2979–2988.
https://doi.org/10.1182/blood-2006-05-023507
Published: 2006
Includes: Supplemental data