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Robert Wynn, MD
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Journal Articles

Intention to Treat Analysis of Real-World Outcomes Following Tisgenlecleucel Therapy for Pediatric and Young Adult ALL through a National Access Programme

Sara Ghorashian, FRCPath, PhD, Caroline Furness, Michelle Cummins, John A Snowden, BSc (Hons), MBChB, MD FRCP, FRCPath, Maeve A O'Reilly, MBBCHBAO, Claire Roddie, PhD MD, Lorna Neill, Emma Nicholson, Caroline Besley, MBBChir, MRCPath, MRCP, Sridhar Chaganti, MDPhDMRCP,FRCPath, John Gillson, MD, Antonio Pagliuca, MBBS, MA, FRCP, FRCPath, Anna Castleton, FRCPath, Amit Patel, MBBS,PhDFRCPath,MRCP, Peter Clark, MA MDFRCP, Robert Fernley, Robert Wynn, MD, Ajay Vora, MD, David I. Marks, MB, MS, FRACP, PhD FRCPath, Geoff Shenton, Persis J Amrolia, FRCP, FRCPath, PhD, Denise Bonney, Rachael E Hough, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 18–19.
https://doi.org/10.1182/blood-2020-138438
Published: 2020
Journal Articles

Clonal Dynamics of Early Responder and Long-Term Surviving CAR-T Cells in Humans

Christine Rivat, Natalia Izotova, Rachel Richardson, MSc, Danilo Pellin, Rachael Hough, Robert Wynn, MD, Kim Champion, Andre Lopes, Sara Ghorashian, FRCPath, PhD, Martin Pule, Adrian J. Thrasher, MBBS, PhD FMedSci, Luca Biasco, PhD, Persis J Amrolia, FRCP, FRCPath, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 52.
https://doi.org/10.1182/blood-2019-125916
Published: 2019
Journal Articles

Phase I Study of AUTO3, a Bicistronic Chimeric Antigen Receptor (CAR) T-Cell Therapy Targeting CD19 and CD22, in Pediatric Patients with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia (r/r B-ALL): Amelia Study

Persis J Amrolia, FRCP, FRCPath, PhD, Robert Wynn, MD, Rachael E Hough, MD, Ajay Vora, Denise Bonney, Paul Veys, MD PhD, Robert Chiesa, Kanchan Rao, Liz Clark, Muhammad Al-Hajj, Shaun P Cordoba, PhD, Shimobi Onuoha, PhD, Ekaterini Kotsopoulou, Nushmia Z Khokhar, Martin Pule, MD, Vijay G R Peddareddigari
Journal: Blood
Blood (2019) 134 (Supplement_1): 2620.
https://doi.org/10.1182/blood-2019-123424
Published: 2019
Journal Articles

Simultaneous Targeting of CD19 and CD22: Phase I Study of AUTO3, a Bicistronic Chimeric Antigen Receptor (CAR) T-Cell Therapy, in Pediatric Patients with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia (r/r B-ALL): Amelia Study

Persis J Amrolia, FRCP, FRCPath, PhD, Robert Wynn, MD, Rachael Hough, MD BMBS, FRCP, FRCPath, Ajay Vora, MD, Denise Bonney, Paul Veys, MD PhD, Kanchan Rao, Robert Chiesa, Muhammad Al-Hajj, Shaun P Cordoba, PhD, Shimobi Onuoha, PhD, Ekaterini Kotsopoulou, Nushmia Z Khokhar, Martin Pule, PhD, Vijay G R Peddareddigari
Journal: Blood
Blood (2018) 132 (Supplement 1): 279.
https://doi.org/10.1182/blood-2018-99-118616
Published: 2018
Journal Articles

Immune Mediated Cytopenia's Following Cord Blood Transplantation for Hurler's Syndrome: A Failure of Pre-Transplant Immune Suppression

David Deambrosis, MBBS, FRACP, Ryan Hum, Prashant Hiwarkar, Kay Poulton, Denise Bonney, Helen Jane Campbell, FRCP, MD FRCPath, Robert Wynn, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3374.
https://doi.org/10.1182/blood-2018-99-112995
Published: 2018
Journal Articles

Allogeneic Hematopoietic Stem Cell Transplantation in Children and Adults with Chronic Granulomatous Disease (CGD): A Study of the Inborn Errors Working Party (IEWP) of the EBMT

Robert Chiesa, Junfeng Wang, Henric-Jan Blok, Benedicte Neven, MD, Despina Moshous, MD, Ansgar Schulz, MD, Manfred Hoenig, MD, Michael H. Albert, MD, Fabian Hauck, MD, Amal Al-Seraihy, MD, Jolanta Gozdzik, MD PhD, Per Ljungman, MD PhD, Caroline A. Lindemans, MD, Krzysztof Kalwak, MD, Brigitte Strahm, PD Dr., Urs Schanz, MD, Petr Sedlacek, MD, Karl-Walter Sykora, MD, Serap Aksoylar, MD, Franco Locatelli, Polina Stepensky, MD, Robert Wynn, MD, Su Han Lum, MD, Marco Zecca, MD, Paul Veys, MD PhD, Andrew Gennery, MD, Matthias Felber, MD, Arjan Lankester, MD PhD, Tayfun Guengoer, MD, Mary Slatter, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 970.
https://doi.org/10.1182/blood-2018-99-114841
Published: 2018
Journal Articles

A Novel Low Affinity CD19CAR Results in Durable Disease Remissions and Prolonged CAR T Cell Persistence without Severe CRS or Neurotoxicity in Patients with Paediatric ALL

Sara Ghorashian, FRCPath, PhD, Anne Marijn Kramer, MD, Sarah Jayne Albon, BSc, MSc, Gary Wright, Fernanda Castro, Bilyana Popova, Joan Casanovas Company, Catherine Irving, Winston Vetharoy, Rachel Richardson, Danielle Pinner, Jan Chu, Giovanna Lucchini, MD, Juliana Silva, MD, Oana Ciocarlie, Sarah Inglott, Kim Champion, Allan Hackshaw, Farzin Farzaneh, PhD, Robert Chiesa, Kanchan Rao, Anupama Gopala Rao, MB, MRCP, MRCPath, Philip Ancliffe, MD, Sujith Samarasinghe, Ajay Vora, MD, Paul Veys, MD PhD, Rachael Hough, MD BMBS, FRCP, FRCPath, Robert Wynn, MD, Martin Pule, PhD, Persis J Amrolia
Journal: Blood
Blood (2017) 130 (Supplement 1): 806.
https://doi.org/10.1182/blood.V130.Suppl_1.806.806
Published: 2017
Journal Articles

G-CSF Vs Haematopoietic Stem Cell Transplantation in Severe Congenital Neutropenia with ELANE Mutation: Role of G-CSF Dose. a Retrospective Controlled Study on Behalf of Saawp (Severe Aplastic Anemia Working Party) of the EBMT, of the Stem Cell Transplant for Immunodeficiency Group in Europe (SCETIDE), of the Severe Chronic Neutropenia French Registry (SCNFR) and Italian Neutropenia Registry (INR)

Francesca Fioredda, MD, Filomena Pierri, Sabrina Zanardi, Bobby Gaspar, Phil Ancliff, Marc Bierings, MD PhD, Gulyuz Ozturk, Owen Smith, MD, Paul Veys, MD PhD, Per Ljungman, Regis Peffault De Latour, MD PhD, Reuven Or, MD, Robert Wynn, MD, Krzysztof Kalwak, MD, Giovanna Russo, MD, Fabio Tucci, MD, Christine M. Knoll, MD, Baldo Martire, Claudio Favre, MD, Christine bellanne Chantelot, MDPhD, Blandine Beaupain, MsC, Jean Donadieu, MD, Carlo Dufour, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2267.
https://doi.org/10.1182/blood.V130.Suppl_1.2267.2267
Published: 2017
Journal Articles

Allogeneic Stem Cell Transplantation for the Treatment of Lymphoproliferative Disorders in Patients Affected By Primary Immunodeficiencies: The UK Experience

Giulia Prunotto, Giovanna Lucchini, MD, Sujith Samarasinghe, Robert Wynn, MD, Ajay Vora, MD, Ben Carpenter, Claire Gowdy, Kieran Mchugh, Andrew Gennery, MD, Paul Veys, MD PhD, Christopher Bacon, Simon Bomken
Journal: Blood
Blood (2017) 130 (Supplement 1): 4573.
https://doi.org/10.1182/blood.V130.Suppl_1.4573.4573
Published: 2017
Journal Articles

Poor Outcome of Domino Hematopoietic Stem Cell Transplantation in Humans - an International Case Series

Mirjam Belderbos, MD PhD, Andrew Gennery, MD, Christopher C. Dvorak, MD, Henric-Jan Blok, Juliana Silva, MD, Paul Veys, MD PhD, Benedicte Neven, MD, Rebecca Buckley, MD, Theresa Cole, MD, Morton Jerome Cowan, MD, W. Scott Goebel, MD PhD, Manfred Hoenig, MD, Caroline Kuo, MD, Richard Stiehm, MD PhD, Robert Wynn, MD, Marc Bierings, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2032.
https://doi.org/10.1182/blood.V130.Suppl_1.2032.2032
Published: 2017
Journal Articles

Hematopoietic Stem Cell Transplantation in 65 Patients with Leukocyte Adhesion Deficiency Type I and Type III — A Retrospective Multi-Center Study

Shahrzad Bakhtiar, MD, Dirk-Jan Eikema, Henric-Jan Blok, Mouhab Ayas, MD, Franco Locatelli, MD PhD, Pietro Merli, MD, Amos Toren, MD PhD, Gal Goldstein, MD, Gerard Michel, MD, Gülyüz Öztürk, MD, Ansgar Schulz, MD, Carsten Heilmann, MDc, Robert Wynn, MD, Olga Aleinikova, MD PhD, Yves Bertrand, MD, Abdelghani Tbakhi, MD, Ardeshir Ghavamzadeh, MD, Paul Veys, MD PhD, Arjan Lankester, MD PhD, Peter Bader, MD PhD, Andrew Gennery, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3330.
https://doi.org/10.1182/blood.V130.Suppl_1.3330.3330
Published: 2017
Journal Articles

Treatment Dilemmas in Asymptomatic Children with Primary Haemophagocytic Lymphohistiocytosis

Giovanna Lucchini, MD, Rebecca A Marsh, Kimberly Gilmour, Austen Worth, Anupama Rao, Claire Booth, Persis J Amrolia, Juliana Silva, MD, Robert Chiesa, Robert Wynn, MD, Kai Lehmberg, Itziar Astigarraga, Tayfun Guengoer, Jan Stary, Despina Moshous, Marianne Ifversen, Stephan Ehl, Daniel Zinn, MD, Paul Veys, MD PhD, Kanchan Rao
Journal: Blood
Blood (2017) 130 (Supplement 1): 3564.
https://doi.org/10.1182/blood.V130.Suppl_1.3564.3564
Published: 2017
Journal Articles

Impact Of Prophylaxis With Defibrotide On The Occurrence Of Acute GvHD In Allogeneic HSCT

Selim Corbacioglu, MD, Simone Cesaro, MD, Maura Faraci, MD, Bernd Gruhn, Jaap J Boelens, MD, PhD, Ansgar Schulz, MD, Ingo Mueller, Jerry Stein, MD, Robert Wynn, MD, Johann Greil, MD, Karl-Walter Sykora, MD, Jacek Toporski, MD, PhD, Petr Sedlacek, Paul G. Schlegel, MD, Karoline Ehlert, MD, Christine Mauz-Koerholz, MD, Peter Bader, Elena Tudone, Maria Ballabio, MD, Carin Heringa, MD, Christina Peters
Journal: Blood
Blood (2013) 122 (21): 4591.
https://doi.org/10.1182/blood.V122.21.4591.4591
Published: 2013
Journal Articles

Excess Heparan Sulphate Inhibits CXCL12-Mediated Hematopoietic Cell Migration and Engraftment After Bone Marrow Transplant in Mice with Mucopolysaccharidosis Type I,

H. Angharad Watson, PhD, Rebecca J Holley, PhD, Kia J Langford-Smith, Fiona L Wilkinson, PhD, Toin H van Kuppevelt, Robert Wynn, MD, J. Ed Wraith, Catherine L R Merry, Brian W Bigger, PhD
Journal: Blood
Blood (2011) 118 (21): 4010.
https://doi.org/10.1182/blood.V118.21.4010.4010
Published: 2011
Journal Articles

Correction of Immune and Enzyme Deficiency by Bone Marrow Transplant in PNP Deficient SCID

Vikramajit Singh, MRCP, Robert Wynn, MD, Denise Bonney, PhD, Stephen Hughes, MD, Kay Poulton, PhD, Helena Lee, PhD
Journal: Blood
Blood (2011) 118 (21): 4556.
https://doi.org/10.1182/blood.V118.21.4556.4556
Published: 2011
Journal Articles

Risk Factor Analysis of Outcomes after Unrelated Cord Blood Transplantation for Children with Hurler’s Syndrome. An Eurocord-Duke University Collaborative Study.

Jaap Jan Boelens, MD, PhD, Vanderson Rocha, MD, Mieke Aldenhoven, MD, Robert Wynn, MD, Anne O’Meara, MD, Marina Cavazzana-Calvo, MD PhD, Irina Ionescu, MD, Suhag Parikh, MD, Vinod Prasad, MD, Maria Escolar, MD, Eliane Gluckman, MD PhD, Joanne Kurtzberg, MD
Journal: Blood
Blood (2007) 110 (11): 5076.
https://doi.org/10.1182/blood.V110.11.5076.5076
Published: 2007