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Rico Hagelaar
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Journal Articles

Single-Cell Whole Genome Sequencing Reveals the Evolution and Migration of Lymphoma

Alexander S. Steemers, Vera M Poort, Ruben Van Boxtel, Friederike Meyer-Wentrup, Rico Hagelaar, Niels M Groenen
Journal: Blood
Blood (2024) 144 (Supplement 1): 2735.
https://doi.org/10.1182/blood-2024-193031
Published: 2024
Journal Articles

Transient Differentiation-State Plasticity during Initiation of Pediatric Acute Lymphoblastic Leukemia

Vera M Poort, Rico Hagelaar, Mark van Roosmalen, Laurianne Trabut, Jessica G.C.A.M. Buijs-Gladdines, Diego Montiel González, Bram van Wijk, Jules P.P. Meijerink, Ruben Van Boxtel
Journal: Blood
Blood (2023) 142 (Supplement 1): 42.
https://doi.org/10.1182/blood-2023-188891
Published: 2023
Journal Articles

Establishment and Characterization of a Model of Acquired Resistance to DOT1L Inhibition in KMT2A -Rearranged Acute Lymphoblastic Leukemia Cells

Pauline Schneider, Susan T.C.J.M. Arentsen-Peters, Nicholas T. Crump, Alastair Smith, Rico Hagelaar, Fabienne R.S. Adriaanse, Romy S. Bos, Kirsten S. Vrenken, Dedeke rockx-Brouwer, Ziqin Tang, Wilbert P. Vermeij, Anja De Jong, Bianca Koopmans, M.Emmy M. Dolman, Thomas A. Milne, Rob Pieters, Ronald W. Stam
Journal: Blood
Blood (2022) 140 (Supplement 1): 8760–8761.
https://doi.org/10.1182/blood-2022-166310
Published: 2022
Journal Articles

Single-Cell Multi-Omics to Infer Hierarchical Ancestry and Organization of Subclones in Acute Lymphoblastic Leukemia

Vera M Poort, Rico Hagelaar, Diego Montiel González, Jessica G.C.A.M. Buijs-Gladdines, Laurianne Trabut, Bram van Wijk, Jules PP Meijerink, Ruben Van Boxtel
Journal: Blood
Blood (2022) 140 (Supplement 1): 5909–5910.
https://doi.org/10.1182/blood-2022-166205
Published: 2022
Journal Articles

BTK inhibition sensitizes acute lymphoblastic leukemia to asparaginase by suppressing the amino acid response pathway

Miriam Butler, Dorette S. van Ingen Schenau, Jiangyan Yu, Silvia Jenni, Maria P. Dobay, Rico Hagelaar, Britt M. T. Vervoort, Trisha M. Tee, Fieke W. Hoff, Jules P. Meijerink, Steven M. Kornblau, Beat Bornhauser, Jean-Pierre Bourquin, Roland P. Kuiper, Laurens T. van der Meer, Frank N. van Leeuwen
Journal: Blood
Blood (2021) 138 (23): 2383–2395.
https://doi.org/10.1182/blood.2021011787
Published: 2021
Includes: Supplemental data
Journal Articles

Methionine Restriction As a Novel Therapeutic Strategy for MLL ( KMT2A) -Rearranged Acute Lymphoblastic Leukemia

Trisha Tee, Titine Ruiter, Ahmed Dahaoui, Dorette van Ingen Schenau, Rico Hagelaar, Laurens van der Meer, Frank van Leeuwen
Journal: Blood
Blood (2021) 138 (Supplement 1): 2269.
https://doi.org/10.1182/blood-2021-145308
Published: 2021
Journal Articles

Elevated Enhancer-Oncogene Contacts and Higher Oncogene Expression Levels By Recurrent CTCF inactivating Mutations in T Cell Acute Lymphoblastic Leukemia

Willem K. Smits, Carlo Vermeulen, Rico Hagelaar, Shunsuke Kimura, Eric Vroegindeweij, Jessica G.C.A.M. Buijs-Gladdines, Ellen Van De Geer, Marjon J.A.M. Verstegen, Erik Splinter, Simon V. van Reijmersdal, Arjan Buijs, Niels Galjart, Winfried Van Eyndhoven, Max Jan Van Min, Roland P Kuiper, Patrick Kemmeren, Charles G. Mullighan, Wouter De Laat, Jules P.P. Meijerink
Journal: Blood
Blood (2021) 138 (Supplement 1): 501.
https://doi.org/10.1182/blood-2021-152221
Published: 2021
Journal Articles

Manipulating MEF2C: Discovering Novel Drugs to Target ETP-ALL

Mariska T. Meijer, Valentina Cordo', Rico Hagelaar, Willem K. Smits, Jules PP Meijerink
Journal: Blood
Blood (2021) 138 (Supplement 1): 3325.
https://doi.org/10.1182/blood-2021-150176
Published: 2021
Journal Articles

Phospho-Proteomic Profiling of T-Cell Acute Lymphoblastic Leukemia Identifies Targetable Kinase Activities and Novel Treatment Combination Strategies

Valentina Cordo', MSc, Rico Hagelaar, Sander Piersma, Richard Goeij-de Haas, Thang V Pham, Jelle Dylus, Guido Zaman, PhD, Connie Jimenez, PhD, Jules P.P. Meijerink, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 14–15.
https://doi.org/10.1182/blood-2020-139259
Published: 2020
Journal Articles

Phospho-Proteomic Profiling of T-Cell Acute Lymphoblastic Leukemia Identifies Specific Kinase Activation Signatures That Can Predict Response to Targeted Therapy

Valentina Cordo', MSc, Rico Hagelaar, Sander Piersma, Thang V Pham, Connie Jimenez, PhD, Jules P.P. Meijerink, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4649.
https://doi.org/10.1182/blood-2019-122898
Published: 2019
Journal Articles

A Test to Quantify NOTCH Pathway Activity in T Cell Acute Lymphoblastic Leukemia Patients

Kirsten Canté-Barrett, PhD, Laurent Holtzer, PhD, Henk van Ooijen, PhD, Rico Hagelaar, Valentina Cordo', MSc, Wim Verhaegh, PhD, Anja van de Stolpe, MD PhD, Jules P.P. Meijerink, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4661.
https://doi.org/10.1182/blood-2019-122856
Published: 2019