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Journal Articles

Janus Kinase (JAK)-2 Does Not Play a Role in Bcr-Abl Signaling in Philadelphia Chromosome (Ph)-Positive (p190) Acute Lymphoblastic Leukemia (ALL) Cells.

Stefan H. Faderl, MD, Quin Van, BS, Patricia E. Koch, MS, David M. Harris, BS, Inbal Hallevi, PhD, Zhiming Liu, BS, Yongtao Wang, MD, Alessandra Ferrajoli, MD, Zeev Estrov, MD

Blood (2007) 110 (11): 4241.

https://doi.org/10.1182/blood.V110.11.4241.4241

Published: 2007

Journal Articles

The Synthetic Hest Shock Protein (Hsp) 90 Inhibitor EC141 Induces Degradation of the Bcr-Abl p190 Protein and Apoptosis of Philadelphia Chromosome (Ph)-Positive Acute Lymphoblastic Leukemia (ALL) Cells.

Alessandra Ferrajoli, MD, Yongtao Wang, MD, Susan M. O’Brien, MD, Stefan H. Faderl, MD, David M. Harris, BS, Quin Van, BS, Inbal Hallevi, PhD, Zhiming Liu, BS, Patricia E. Koch, MS, John Sensintaffar, MS, Francis Burrows, PhD, Hagop M. Kantarjian, MD, Michael J. Keating, MB, BS, Zeev Estrov, MD

Blood (2007) 110 (11): 2784.

https://doi.org/10.1182/blood.V110.11.2784.2784

Published: 2007

Journal Articles

Structure-Based Drug Design of c-Kit Inhibitors for Use in the Treatment of Acute Myeloid Leukemia.

David S. Maxwell, PhD, Ashutosh Pal, Zhenghong Peng, Alexandr Shavrin, Stefan Faderl, MD, David Harris, Quin Van, Zhiming Liu, Srdan Verstovsek, MD PhD, Taghi Manshouri, MB BS, Alessandra Ferrajoli, MD, Hagop M. Kantarjian, MD, Zeev Estrov, MD, William G. Bornmann, PhD

Blood (2006) 108 (11): 1906.

https://doi.org/10.1182/blood.V108.11.1906.1906

Published: 2006

Journal Articles

APCK110, a Novel and Potent Inhibitor of c-Kit, Blocks Phosphorylation of AKT and STAT3, Induces Apoptosis, and Inhibits Proliferation of Acute Myeloid Leukemia (AML) Cells.

Stefan Faderl, MD, William Bornmann, PhD, David Maxwell, PhD, Ashutosh Pal, Zheng-Hong Peng, Aleksandr Shavrin, David Harris, Quin Van, Liu Zhiming, Srdan Verstovsek, MD, PhD, Taghi Manshouri, MS, BS, Alessandra Ferrajoli, MD, Hagop M. Kantarjian, MD, Zeev Estrov, MD

Blood (2006) 108 (11): 153.

https://doi.org/10.1182/blood.V108.11.153.153

Published: 2006

Journal Articles

Atiprimod Blocks STAT3 and STAT5 Phosphorylation, Inhibits Proliferation, and Induces Apoptosis in Acute Myeloid Leukemia (AML) but Not Normal Cells.

Stefan Faderl, MD, Alessandra Ferrajoli, MD, David Harris, Quin Van, Hagop M. Kantarjian, MD, Zeev Estrov, MD

Blood (2005) 106 (11): 2462.

https://doi.org/10.1182/blood.V106.11.2462.2462

Published: 2005

Journal Articles

WP-1034, a Novel Jak-Stat Inhibitor, Has Proapoptotic and Antileukemic Activity in Acute Myeloid Leukemia (AML) Cell Lines and AML Patient Samples.

Stefan Faderl, MD, Alessandra Ferrajoli, MD, David Harris, Quin Van, Waldemar Priebe, PhD, Zeev Estrov, MD

Blood (2004) 104 (11): 2528.

https://doi.org/10.1182/blood.V104.11.2528.2528

Published: 2004

Journal Articles

WP-1066, a Next-Generation Member of JAK-Stat Inhibitors, Induces Cell Cycle Arrest, Abrogates Proliferation, and Induces Apoptosis of Acute Myeloid Leukemia (AML) Cells.

Alessandra Ferrajoli, M.D., Stefan Faderl, M.D., Quin Van, B.S., David M. Harris, B.S., Waldemar Priebe, Ph.D., Hagop M. Kantarjian, M.D., Moshe Talpaz, M.D., Zeev Estrov, M.D.

Blood (2004) 104 (11): 1169.

https://doi.org/10.1182/blood.V104.11.1169.1169

Published: 2004

Journal Articles

Resveratrol blocks interleukin-1β–induced activation of the nuclear transcription factor NF-κB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells

Zeev Estrov, Shishir Shishodia, Stefan Faderl, David Harris, Quin Van, Hagop M. Kantarjian, Moshe Talpaz, Bharat B. Aggarwal

Blood (2003) 102 (3): 987–995.

https://doi.org/10.1182/blood-2002-11-3550

Published: 2003

Journal Articles

Granulocyte-macrophage colony-stimulating factor (GM-CSF) induces antiapoptotic and proapoptotic signals in acute myeloid leukemia

Stefan Faderl, David Harris, Quin Van, Hagop M. Kantarjian, Moshe Talpaz, Zeev Estrov

Blood (2003) 102 (2): 630–637.

https://doi.org/10.1182/blood-2002-06-1890

Published: 2003

Journal Articles

Phenylarsine Oxide Blocks Interleukin-1β–Induced Activation of the Nuclear Transcription Factor NF-κB, Inhibits Proliferation, and Induces Apoptosis of Acute Myelogenous Leukemia Cells

Zeev Estrov, Sunil K. Manna, David Harris, Quin Van, Elihu H. Estey, Hagop M. Kantarjian, Moshe Talpaz, Bharat B. Aggarwal

Blood (1999) 94 (8): 2844–2853.

https://doi.org/10.1182/blood.V94.8.2844.420k43_2844_2853

Published: 1999

Journal Articles

Caspase 2 and Caspase 3 Protein Levels as Predictors of Survival in Acute Myelogenous Leukemia

Zeev Estrov, Peter F. Thall, Moshe Talpaz, Elihu H. Estey, Hagop M. Kantarjian, Michael Andreeff, David Harris, Quin Van, Monika Walterscheid, Steven M. Kornblau

Blood (1998) 92 (9): 3090–3097.

https://doi.org/10.1182/blood.V92.9.3090

Published: 1998

NARROW

Janus Kinase (JAK)-2 Does Not Play a Role in Bcr-Abl Signaling in Philadelphia Chromosome (Ph)-Positive (p190) Acute Lymphoblastic Leukemia (ALL) Cells.

The Synthetic Hest Shock Protein (Hsp) 90 Inhibitor EC141 Induces Degradation of the Bcr-Abl p190 Protein and Apoptosis of Philadelphia Chromosome (Ph)-Positive Acute Lymphoblastic Leukemia (ALL) Cells.

Structure-Based Drug Design of c-Kit Inhibitors for Use in the Treatment of Acute Myeloid Leukemia.

APCK110, a Novel and Potent Inhibitor of c-Kit, Blocks Phosphorylation of AKT and STAT3, Induces Apoptosis, and Inhibits Proliferation of Acute Myeloid Leukemia (AML) Cells.

Atiprimod Blocks STAT3 and STAT5 Phosphorylation, Inhibits Proliferation, and Induces Apoptosis in Acute Myeloid Leukemia (AML) but Not Normal Cells.

WP-1034, a Novel Jak-Stat Inhibitor, Has Proapoptotic and Antileukemic Activity in Acute Myeloid Leukemia (AML) Cell Lines and AML Patient Samples.

WP-1066, a Next-Generation Member of JAK-Stat Inhibitors, Induces Cell Cycle Arrest, Abrogates Proliferation, and Induces Apoptosis of Acute Myeloid Leukemia (AML) Cells.

Resveratrol blocks interleukin-1β–induced activation of the nuclear transcription factor NF-κB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells

Granulocyte-macrophage colony-stimulating factor (GM-CSF) induces antiapoptotic and proapoptotic signals in acute myeloid leukemia

Phenylarsine Oxide Blocks Interleukin-1β–Induced Activation of the Nuclear Transcription Factor NF-κB, Inhibits Proliferation, and Induces Apoptosis of Acute Myelogenous Leukemia Cells

Caspase 2 and Caspase 3 Protein Levels as Predictors of Survival in Acute Myelogenous Leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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