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Journal Articles

A Rare Cell State Underpins Diverse Mechanisms of Adaptive Resistance to CAR T-Cell Therapy in B-Cell Acute Lymphoblastic Leukemia

James A Kuzich, Laure Talarmain, Dane Vassiliadis, Andrew A Guirguis, Jack D Chan, Paul A Beavis, Phillip K Darcy, Ashley P Ng, Mark A Dawson
Journal: Blood
Blood (2023) 142 (Supplement 1): 887.
https://doi.org/10.1182/blood-2023-191111
Published: 2023
Journal Articles

Improved MRD Negativity Rates in Adverse Genomic Risk B-ALL Patients with Chemotherapy / Blinatumomab Induction: Experience from the Australasian Leukaemia Lymphoma Group (ALLG) ALL06/09 Studies

Deborah L White, Jacqueline A Rehn, Caitlin E Schutz, Susan L Heatley, Laura N Eadie, Ashlee Thomson, Elyse C Page, Michael Osborn, Shane Gangatharan, Ashley P Ng, Shaun Fleming, Pasquale Fedele, Toby Trahair, John Casey, Sally Mapp, Carol CY Cheung, Tasman Armytage, Michelle Henderson, Rosemary Sutton, Stephen Robert Larsen, Peter Presgrave, John Kwan, Samuel Bennett, Chun Yew Fong, Luciano Dalla-Pozza, David T Yeung, Matthew Greenwood
Journal: Blood
Blood (2023) 142 (Supplement 1): 1609.
https://doi.org/10.1182/blood-2023-178473
Published: 2023
Journal Articles

All wired up: heptads in hematopoiesis

Ashley P. Ng
Journal: Blood
Blood (2023) 142 (17): 1407–1409.
https://doi.org/10.1182/blood.2023022014
Published: 2023
Journal Articles

Iron homeostasis governs erythroid phenotype in polycythemia vera

Cavan Bennett, Victoria E. Jackson, Anne Pettikiriarachchi, Thomas Hayman, Ute Schaeper, Gemma Moir-Meyer, Katherine Fielding, Ricardo Ataide, Danielle Clucas, Andrew Baldi, Alexandra L. Garnham, Connie S. N. Li-Wai-Suen, Stephen J. Loughran, E. Joanna Baxter, Anthony R. Green, Warren S. Alexander, Melanie Bahlo, Kate Burbury, Ashley P. Ng, Sant-Rayn Pasricha
Journal: Blood
Blood (2023) 141 (26): 3199–3214.
https://doi.org/10.1182/blood.2022016779
Published: 2023
Includes: Supplemental data
Journal Articles

Blinatumomab in Combination with an Intensive Pediatric Protocol Results in High Rates of Day 79 MRD Negativity in Adolescent and Young Adult Acute Lymphoblastic Leukemia - Preliminary Results of the Australasian Leukaemia and Lymphoma Group (ALLG) ALL09 "Sublime” Study

Matthew Greenwood, Shane Gangatharan, Michael Philip Osborn, Ashley P Ng, Shaun Fleming, Pasquale Fedele, Toby Trahair, John Casey, Sally Mapp, Carol Cheung, Tasman Armytage, Michelle Henderson, Rosemary Sutton, Philip McCloud, Stephen R Larsen, Peter Presgrave, John Kwan, Samuel Bennett, Chun Yew Fong, Luciano Dalla Pozza
Journal: Blood
Blood (2022) 140 (Supplement 1): 8971–8972.
https://doi.org/10.1182/blood-2022-168568
Published: 2022
Journal Articles

Updated Interim Results from a Phase 1 Study of HPN217, a Half-Life Extended Tri-Specific T Cell Activating Construct (TriTAC®) Targeting B Cell Maturation Antigen (BCMA) for Relapsed/Refractory Multiple Myeloma (RRMM)

Al-Ola Abdallah, Andrew J Cowan, Xavier Leleu, Cyrille Touzeau, Brea Lipe, Eva Medvedova, Caitlin Costello, Jens Hillengass, P. Leif Bergsagel, Raya Mawad, Henning Schade, Daniel Morillo Giles, Albert Oriol, Yifah Yaron, Patrick P Ng, Sumit Madan
Journal: Blood
Blood (2022) 140 (Supplement 1): 7284–7285.
https://doi.org/10.1182/blood-2022-159665
Published: 2022
Journal Articles

Diagnostic Utility of Multimodal Genomic Profiling for Molecular Classification and MRD Assessment in Adult B-Cell Acute Lymphoblastic Leukemia

Georgina L Ryland, Ashish Bajel, Michael Dickinson, Paul G Ekert, Oliver Hofmann, Maarten IJzerman, Ashley P Ng, Alicia Oshlack, Breon Schmidt, Ing S Tiong, Martin Vu, David Alan Westerman, Sean Grimmond, Piers Blombery
Journal: Blood
Blood (2021) 138 (Supplement 1): 274.
https://doi.org/10.1182/blood-2021-146396
Published: 2021
Journal Articles

The Effects of BCMA Expression, Soluble BCMA, and Combination Therapeutics on the Anti-Tumor Activity of HPN217, a BCMA-Targeting Tri-Specific T Cell Engager Against Multiple Myeloma

Patrick P Ng, Wade Aaron, Evan Callihan, Golzar Hemmati, Che-Leung Law, Abdel Kareem Azab, Laura Sun
Journal: Blood
Blood (2021) 138 (Supplement 1): 1185.
https://doi.org/10.1182/blood-2021-151880
Published: 2021
Journal Articles

Unraveling a T-ALL Tapestri

Ashley P. Ng
Journal: Blood
Blood (2021) 137 (6): 726–727.
https://doi.org/10.1182/blood.2020008467
Published: 2021
Journal Articles

The ITK Inhibitor Cpi-818 Blocks Activation of T Cells from Autoimmune Lymphoproliferative Syndrome (ALPS) Patients and Is Active in a Murine Model of ALPS

V. Koneti Koneti Rao, MD FRCPA, Patrick P. Ng, PhD, Craig M. Hill, PhD, Richard A. Miller, MD, Joseph J. Buggy, PhD, James W. Janc, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 36–37.
https://doi.org/10.1182/blood-2020-137631
Published: 2020
Journal Articles

Development and survival of MYC-driven lymphomas require the MYC antagonist MNT to curb MYC-induced apoptosis

Hai Vu Nguyen, Cassandra J. Vandenberg, Ashley P. Ng, Mikara R. Robati, Natasha S. Anstee, Joel Rimes, Edwin D. Hawkins, Suzanne Cory
Journal: Blood
Blood (2020) 135 (13): 1019–1031.
https://doi.org/10.1182/blood.2019003014
Published: 2020
Includes: Supplemental data
Journal Articles

Preliminary Clinical Data from a Phase 1 Trial with CPI-818, a Selective ITK Inhibitor That Preferentially Blocks the Growth of T Lymphoma Cells

Patrick P. Ng, PhD, Mehrdad Mobasher, MD MPH, Kitman S. Yeung, MS, Andrew N. Hotson, PhD, Craig M. Hill, PhD, Antonett Madriaga, MS, Trang P. Dao-Pick, MA, Erik Verner, PhD, Dejan Radeski, MBBS, FRACP, FRCPA, Michael S. Khodadoust, MD PhD, Youn H. Kim, MD, Richard A. Miller, MD, Joseph J. Buggy, PhD, James W. Janc, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1571.
https://doi.org/10.1182/blood-2019-127338
Published: 2019
Journal Articles

I myelofibrosis! Veni VitD! Et tu, macrophage?

Ashley P. Ng
Journal: Blood
Blood (2019) 133 (15): 1613–1615.
https://doi.org/10.1182/blood-2019-02-900779
Published: 2019
Journal Articles

Identification of Potent BH3-Mimetic Combinations Targeting Pro-Survival Pathways in Human B-Cell Acute Lymphoblastic Leukemia

Donia M Moujalled, PhD, Diane T Hanna, Giovanna Pomilio, Veronique Litalien, Shaun Fleming, Marie Chanrion, Ana-Leticia Maragno, Laurence Kraus-Berthier, Seong Lin Khaw, Guillaume Lessene, David Huang, Andrew W. Roberts, MBBS, PhD, Olivier Geneste, Paul G Ekert, Ashley P Ng, Andrew H Wei, MBBS,PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 567.
https://doi.org/10.1182/blood-2018-99-114051
Published: 2018
Journal Articles

Ibrutinib Enhances the Activity of Anti-CD20 Antibodies in an MCL Mouse Model: Effect of Drug at Clinically Relevant Concentrations on ADCC and ADCP

Patrick P. Ng, Daniel K. Lu, Juthamas Sukbuntherng, Jutta K. Neuenburg, Danelle F. James, Betty Y. Chang, PhD
Journal: Blood
Blood (2015) 126 (23): 3998.
https://doi.org/10.1182/blood.V126.23.3998.3998
Published: 2015
Journal Articles

Unsupervised Discovery of Early Markers of Erythroid Maturation in Human Donor Marrow

David P Ng, MD, Brent Wood, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4304.
https://doi.org/10.1182/blood.V124.21.4304.4304
Published: 2014
Journal Articles

B-cell receptors expressed by lymphomas of hepatitis C virus (HCV)–infected patients rarely react with the viral proteins

Brief Report
Patrick P. Ng, Chiung-Chi Kuo, Stanley Wang, Shirit Einav, Luca Arcaini, Marco Paulli, Carol S. Portlock, Joseph Marcotrigiano, Alexander Tarr, Jonathan Ball, Ronald Levy, Shoshana Levy
Journal: Blood
Blood (2014) 123 (10): 1512–1515.
https://doi.org/10.1182/blood-2013-10-532895
Published: 2014
Journal Articles

Screening With Spirometry Is A Useful Predictor Of Later Development Of Non-Infectious Pulmonary Syndromes In Patients Undergoing Allogeneic Stem Cell Transplantation

Thompson A Philip, MBBS, FRACP, FRCPA, Andrew B M Lim, MBBS, FRACP, FRCPA, Mark Tacey, Ramzi Hijazi, MBBS, Ashley P. Ng, MBBS, BMedSc, PhD, FRACP, FRCPA, Jeffrey Szer, BMedSc, MBBS, FRACP, David Ritchie, MBBS, PhD, FRACP, FRCPA, Ashish R. Bajel, MBBS, FRACP, FRCPA
Journal: Blood
Blood (2013) 122 (21): 4603.
https://doi.org/10.1182/blood.V122.21.4603.4603
Published: 2013
Journal Articles

GFI1B Mutation Causes a Platelet Function Defect With Reduced Alpha-Granule Content and Abnormal Aggregation Response

Christopher M Ward, MB, CHB, PhD, Marie-Christine Morel-Kopp, PhD, Qiang Chen, BMed MSc, Hai Po Liang, PhD, Ashley P. Ng, MBBS, BMedSc, PhD, FRACP, FRCPA, Andrew W. Roberts, MBBS, PhD, Melanie Bahlo, PhD, William s Stevenson, MBBS, PhD
Journal: Blood
Blood (2013) 122 (21): 566.
https://doi.org/10.1182/blood.V122.21.566.566
Published: 2013
Journal Articles

Targeting B-Cell Lymphoma with Idiotype-Specific Peptibodies: Toward a Personalized and Tumor-Specific Therapy

James A Torchia, Patrick P Ng, PhD, Homer Chen, Holbrook E Kohrt, MD, PhD, Aurelien Marabelle, MD, MSc, Ash A. Alizadeh, MD, PhD, Ronald Levy, MD
Journal: Blood
Blood (2012) 120 (21): 3713.
https://doi.org/10.1182/blood.V120.21.3713.3713
Published: 2012