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Journal Articles

Clonal Hematopoiesis Driven By Mutations in DNMT3A Promotes Metabolic Disease

Bowen Yan, Qingchen Yuan, Prabhjot Kaur, Annalisse Mckee, Daniil Shabashvili, Olga A. Guryanova

Blood (2024) 144 (Supplement 1): 4057.

https://doi.org/10.1182/blood-2024-208797

Published: 2024

Journal Articles

Compound Loss of Dnmt3a and Kmt2c in Myeloid Malignancies

Prabhjot Kaur, Cassandra Berntsen, James Leonard, Daniil Shabashvili, Qingchen Yuan, Bowen Yan, Richard Lynn Bennett, Alberto Riva, Jonathan D. Licht, Olga A. Guryanova

Blood (2023) 142 (Supplement 1): 4584.

https://doi.org/10.1182/blood-2023-189411

Published: 2023

Journal Articles

Myeloid Master Regulators PU.1 and CEBPA Suppress Leukemogenesis through Downregulating Cell Cycle Related Genes in NPM1 Mutated Leukemia

Karina Hamamoto, Julia Lesperance, Huacheng Luo, Zachary Zaroogian, Olga A. Guryanova, Yi Qiu, Suming Huang

Blood (2023) 142 (Supplement 1): 5690.

https://doi.org/10.1182/blood-2023-189988

Published: 2023

Journal Articles

NPM1 Mutation Reprograms Leukemic Transcription Network Via Reshaping CTCF-Defined TAD Topology

Karina Hamamoto, Qian Lai, Huacheng Luo, Julia Lesperance, Zachary Zaroogian, Jie Zha, Yi Qiu, Olga A Guryanova, Bing Xu, Suming Huang

Blood (2022) 140 (Supplement 1): 722–723.

https://doi.org/10.1182/blood-2022-160367

Published: 2022

Journal Articles

Study of the Dynamics and Diversity of Hematopoietic Stem Cells during Aging and Senolytic Drug Treatment Using Single Cell Transcriptomics

Bowen Yan, Guangrong Zheng, Daohong Zhou, Olga A Guryanova

Blood (2022) 140 (Supplement 1): 5760–5761.

https://doi.org/10.1182/blood-2022-170033

Published: 2022

Journal Articles

Dnmt3a Mutations in the Hematopoietic System Promote Colitis-Associated Colon Cancer: A Model of Clonal Hematopoiesis in Solid Tumors

Yang Feng, Rachel Newsome, Troy Robinson, Robert L. Bowman, Ashley Zuniga, Kendra Hall, Cassandra Bernsten, Daniil Shabashvili, Kathryn Krajcik, Chamara Gunaratne, Zachary Zaroogian, Kartika Venugopal, Heidi Casellas Roman, Ross L. Levine, Alberto Riva, Daniel Kopinke, Christian Jobin, Dorina Avram, Olga A Guryanova

Blood (2021) 138 (Supplement 1): 2161.

https://doi.org/10.1182/blood-2021-149740

Published: 2021

Journal Articles

DNMT3A with Leukemia-Associated R882 Mutations Promotes Fitness Advantage through Functional Heterogeneity within HSCs

Zachary Zaroogian, Chamara Gunaratne, Daniil Shabashvili, Cassandra Berntsen, Yang Feng, Kartika Venugopal, Santhi Pondugula, Olga A Guryanova

Blood (2021) 138 (Supplement 1): 2151.

https://doi.org/10.1182/blood-2021-151007

Published: 2021

Journal Articles

DNMT3A with Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks

Kartika Venugopal, MS, Daniil E Shabashvili, PhD, Jianping Li, MD, Luisa M Posada, Richard Lynn Bennett, PhD, Yang Feng, MS, Daphne Dupere Richer, PhD, Alberto Riva, PhD, Santhi Pondugula, PhD, Jonathan E. Bird, PhD, Jonathan D. Licht, MD, Olga A Guryanova, MD PhD

Blood (2019) 134 (Supplement_1): 535.

https://doi.org/10.1182/blood-2019-128213

Published: 2019

Journal Articles

Hoxblinc Is Aberrantly Expressed in Acute Myeloid Leukemia and Functions As a Potent Oncogenic Long Non-Coding RNA in Leukemogenesis

Ganqian Zhu, PhD, Huacheng Luo, Shi Chen, Qian Lai, Ying Guo, Olga A Guryanova, MDPhD, Yi Qiu, Feng-Chun Yang, MD PhD, Wei Li, Stephen D. Nimer, MD, Suming Huang, Mingjiang Xu, MD PhD

Blood (2018) 132 (Supplement 1): 886.

https://doi.org/10.1182/blood-2018-99-112232

Published: 2018

Journal Articles

Cells with DNMT3A Mutations Are More Sensitive to Cytarabine-Induced DNA Damage

Kartika Venugopal, MS, Jianping Li, MD, Daniil E Shabashvili, PhD, Luisa M Posada, Yang Feng, MS, Daphne Dupere-Richer, PhD, Aditya Bele, PhD, Jonathan D. Licht, MD, Olga A Guryanova, MD PhD

Blood (2018) 132 (Supplement 1): 2643.

https://doi.org/10.1182/blood-2018-99-118708

Published: 2018

Journal Articles

Prmt5 Negatively Regulates Erythropoiesis By Multiple Mechanisms, Including Controlling DNA Methyltransferase 3A Protein Levels

Pierre-Jacques Hamard, PhD, Luisa Luciani, PhD, Fan Liu, PhD, Guoyan Cheng, PhD, Megan A. Hatlen, PhD, Olga A Guryanova, MD, PhD, Xinyang Zhao, PhD, Ross L. Levine, MD, Stephen D. Nimer, MD

Blood (2015) 126 (23): 1181.

https://doi.org/10.1182/blood.V126.23.1181.1181

Published: 2015

Journal Articles

Conditional Loss of Dnmt3a Results in Myeloproliferation and Liver-Specific Myeloid Expansion

Olga A Guryanova, MD PhD, Yen Lieu, PhD, Kaitlyn R Shank, B.S., Sharon Rivera, PhD, Francine E Garrett-Bakelman, MD PhD, Jacob Glass, MD PhD, Matthew D Keller, B.S., Suveg Pandey, B.S., Daniel Tovbin, Abby R Weinstein, Julie Teruya-Feldstein, MD, Omar Abdel-Wahab, MD, Christopher E Mason, PhD, Ari M Melnick, MD, Siddhartha Mukherjee, MD PhD, Ross L. Levine, MD

Blood (2014) 124 (21): 364.

https://doi.org/10.1182/blood.V124.21.364.364

Published: 2014

Journal Articles

Characterizing Transcriptional and Epigenetic Signatures Induced By FLT3-ITD Activation

Barbara Spitzer, MD, Olga A Guryanova, MD PhD, Omar Abdel-Wahab, MD, Nicole Kucine, MD, Mazhar Adli, PhD, Jason N. Berman, MD, Soheil Meshinchi, MD PhD, Bradley Bernstein, MD PhD, Raphael Pelossof, PhD, Christina Leslie, PhD, Ross L. Levine, MD

Blood (2014) 124 (21): 2186.

https://doi.org/10.1182/blood.V124.21.2186.2186

Published: 2014

Journal Articles

Type II Inhibition of JAK2 with NVP-CHZ868 Reverses Type I JAK Inhibitor Persistence and Demonstrates Increased Efficacy in MPN Models

Sara C Meyer, MD PhD, Matthew D Keller, BS, Priya Koppikar, PhD, Olga A Guryanova, MD PhD, Maria Kleppe, PhD, Anna Sophia McKenney, MPH, William R Sellers, MD, Francesco Hofmann, PhD, Fabienne Baffert, Christoph Gaul, PhD, Thomas Radimerski, PhD, Ross L Levine, MD

Blood (2014) 124 (21): 160.

https://doi.org/10.1182/blood.V124.21.160.160

Published: 2014

NARROW

Clonal Hematopoiesis Driven By Mutations in DNMT3A Promotes Metabolic Disease

Compound Loss of Dnmt3a and Kmt2c in Myeloid Malignancies

Myeloid Master Regulators PU.1 and CEBPA Suppress Leukemogenesis through Downregulating Cell Cycle Related Genes in NPM1 Mutated Leukemia

NPM1 Mutation Reprograms Leukemic Transcription Network Via Reshaping CTCF-Defined TAD Topology

Study of the Dynamics and Diversity of Hematopoietic Stem Cells during Aging and Senolytic Drug Treatment Using Single Cell Transcriptomics

Dnmt3a Mutations in the Hematopoietic System Promote Colitis-Associated Colon Cancer: A Model of Clonal Hematopoiesis in Solid Tumors

DNMT3A with Leukemia-Associated R882 Mutations Promotes Fitness Advantage through Functional Heterogeneity within HSCs

DNMT3A with Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks

Hoxblinc Is Aberrantly Expressed in Acute Myeloid Leukemia and Functions As a Potent Oncogenic Long Non-Coding RNA in Leukemogenesis

Cells with DNMT3A Mutations Are More Sensitive to Cytarabine-Induced DNA Damage

Prmt5 Negatively Regulates Erythropoiesis By Multiple Mechanisms, Including Controlling DNA Methyltransferase 3A Protein Levels

Conditional Loss of Dnmt3a Results in Myeloproliferation and Liver-Specific Myeloid Expansion

Characterizing Transcriptional and Epigenetic Signatures Induced By FLT3-ITD Activation

Type II Inhibition of JAK2 with NVP-CHZ868 Reverses Type I JAK Inhibitor Persistence and Demonstrates Increased Efficacy in MPN Models

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American Society of Hematology

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ASH Publications

American Society of Hematology

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