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Journal Articles

DDX41 Is a Tumor Suppressor Gene Associated with Inherited and Acquired Mutations

Blood (2014) 124 (21): 125.

https://doi.org/10.1182/blood.V124.21.125.125

Published: 2014

Journal Articles

Identification Of Leukemia Suppressive Genes By Inducible Overexpression Of The DNA Methyltransferase DNMT3B During Leukemogenesis In Mice

Isabell Schulze, Petra Tschanter, Christian Rohde, PhD, Annika Krause, Heinz Linhart, Katja Hebestreit, Martin Dugas, MD, Frank Rosenbauer, Wolfgang E. Berdel, MD, Carsten Müller-Tidow, MD

Blood (2013) 122 (21): 2493.

https://doi.org/10.1182/blood.V122.21.2493.2493

Published: 2013

Journal Articles

The Clinical and Prognostic Influence Of Mutations In The Cohesin Complex In Acute Myeloid Leukemia

Blood (2013) 122 (21): 1314.

https://doi.org/10.1182/blood.V122.21.1314.1314

Published: 2013

Journal Articles

Landscape Of Genetic Lesions In 944 Patients With Myelodysplastic Syndromes

Blood (2013) 122 (21): 521.

https://doi.org/10.1182/blood.V122.21.521.521

Published: 2013

Journal Articles

The Interlaboratory Robustness of Next-Generation Sequencing (IRON) Study Phase II: Deep-Sequencing Analyses of Hematological Malignancies Performed by an International Network Involving 26 Laboratories

Blood (2012) 120 (21): 1399.

https://doi.org/10.1182/blood.V120.21.1399.1399

Published: 2012

Journal Articles

A Specific DNA Methylation Pattern Is Associated with Delayed Leukemogenesis and Altered Response to Chemotherapeutic Treatment in an Inducible DNMT3b Expressing Mouse Model

Isabell Schulze, Petra Tschanter, MD, Christian Rohde, PhD, Nicole Baeumer, Heinz Linhart, Katja Hebestreit, Wolfgang E. Berdel, MD, Martin Dugas, MD, Carsten Müller-Tidow

Blood (2012) 120 (21): 398.

https://doi.org/10.1182/blood.V120.21.398.398

Published: 2012

Journal Articles

Identification of the PML-RARα Associated DNA Methylome Using Reduced Representation Bisulfite Sequencing in Primary Patient Samples

Christian Rohde, PhD, Till Schoofs, Katja Hebestreit, Hans-Ulrich Klein, PhD, Anika Witten, PhD, Monika Stoll, PhD, Eva Lengfelder, MD, Wolf-Karsten Hofmann, MD, Peter Schlenke, PhD, Stefanie Göllner, PhD, Thomas Büchner, MD, Maria Cristina Sauerland, Steffen Koschmieder, MD, Wolfgang E. Berdel, Martin Dugas, MD, Carsten Müller-Tidow, MD

Blood (2011) 118 (21): 2436.

https://doi.org/10.1182/blood.V118.21.2436.2436

Published: 2011

Journal Articles

Somatic Structural Variations in Pediatric High Hyperdiploid Acute Lymphoblastic Leukemia Revealed by Paired-End Parallel Sequencing

Cai Chen, MD, Christoph Bartenhagen, Michael Gombert, PhD, Vera Okpanyi, PhD, Vera Binder, MD, Silja Roettgers, PhD, Jutta Bradtke, Andrea Teigler-Schlegel, Ute Fischer, PhD, Jochen Harbott, Jianda Hu, MD, Martin Dugas, MD, Arndt Borkhardt, MD

Blood (2011) 118 (21): 401.

https://doi.org/10.1182/blood.V118.21.401.401

Published: 2011

Journal Articles

Whole Genome Amplification with Subsequent High Throughput Sequencing Allows Comprehensive Genome-Wide Analysis of Single Leukemic Cells

Vera Binder, MD, Christoph Bartenhagen, Vera Okpanyi, PhD, Bianca Behrens, Birte Moehlendick, PhD, Hans-Ulrich Klein, PhD, Harald Rieder, MD, Michael Gombert, PhD, Martin Dugas, MD, Nikolas Hendrik Stoecklein, MD, Arndt Borkhardt, MD

Blood (2011) 118 (21): 1437.

https://doi.org/10.1182/blood.V118.21.1437.1437

Published: 2011

Journal Articles

Histone H3 Methylation Mediates All- Trans -Retinoic Acid Responsiveness in Acute Myeloid Leukemia

Tino Schenk, PhD, Stefanie Göllner, PhD, Weihsu Claire Chen, PhD, Louise Howell, BSc, Liqing Jin, MD, Katja Hebestreit, Hans-Ulrich Klein, PhD, Alan K Burnett, MD, Ken I. Mills, PhD, FRCPath, Laurence Marton, MD, Robert Casero, Jr., PhD, Patrick Woster, PhD, Martin Dugas, MD, Jean C.Y. Wang, MD, PhD, John E. Dick, PhD, Carsten Müller-Tidow, MD, Kevin Petrie, PhD, Arthur Zelent, PhD

Blood (2011) 118 (21): 224.

https://doi.org/10.1182/blood.V118.21.224.224

Published: 2011

Journal Articles

Targeted Next-Generation Sequencing and Genome-Wide High-Resolution Copy Number DNA Arrays Allow the Identification of Five Novel RUNX1 Fusions In Hematological Malignancies.

Vera Grossmann, Alexander Kohlmann, PhD, Hans-Ulrich Klein, MA, Sonja Schindela, Susanne Schnittger, PhD, Martin Dugas, MD, Wolfgang Kern, MD, Torsten Haferlach, MD, Claudia Haferlach, MD

Blood (2010) 116 (21): 1193.

https://doi.org/10.1182/blood.V116.21.1193.1193

Published: 2010

Journal Articles

Dominant-Negative Impact of PAX5/TEL on Downstream Targets of PAX5 and Essential Pre-B Cell Receptor Genes

Gabriela B. Iwanski, MD, Nils H. Thoennissen, MD, Joy Nakitandwe, BSc, MSc, PhD, Patricia Lin, Norihiko Kawamata, Rahul Nahar, Parham Ramezani-Rad, Shann-Ching Chen, Sheila Shurtleff, PhD, Daniel Nowak, MD, Christian Ruckert, Martin Dugas, MD, Carsten Bokemeyer, MD, Grazia Fazio, Andrea Biondi, Professor, MD, Giovanni Cazzaniga, PhD, James R. Downing, MD, Markus Müschen, H. Phillip Koeffler, MD

Blood (2010) 116 (21): 3231.

https://doi.org/10.1182/blood.V116.21.3231.3231

Published: 2010

Journal Articles

Global Identification of Genomic Structural Variants In Childhood ETV6/RUNX1 ( TEL/AML1 ) Acute Lymphoblastic Leukemias by Mate-Pair Massively Parallel Sequencing.

Vera Okpanyi, Christoph Bartenhagen, Michael Gombert, PhD, Vera Binder, MD, Hans-Ulrich Klein, MA, Silja Roettgers, PhD, Jochen Harbott, PhD, Martin Dugas, MD, Arndt Borkhardt, MD

Blood (2010) 116 (21): 3364.

https://doi.org/10.1182/blood.V116.21.3364.3364

Published: 2010

Journal Articles

Robust and Sensitive Detection of Insertions, Deletions and Point Mutations In CEBPA , a GC-Rich Content Gene, Using 454 Next-Generation Deep-Sequencing (NGS).

Vera Grossmann, MA, Susanne Schnittger, PhD, Sonja Schindela, Hans-Ulrich Klein, MA, Christiane Eder, PhD, Martin Dugas, MD, Wolfgang Kern, MD, Claudia Haferlach, MD, Torsten Haferlach, MD, Alexander Kohlmann, PhD

Blood (2010) 116 (21): 1657.

https://doi.org/10.1182/blood.V116.21.1657.1657

Published: 2010

Journal Articles

Targeted Next-Generation Sequencing (NGS) Enables a Broad Screening of 95 Molecular Mutations In a One-Step Approach and Detects Recurrent Mutations In AML with a Normal Karyotype In MYH11 and NOTCH1

Alexander Kohlmann, PhD, Vera Grossmann, MA, Hans-Ulrich Klein, MA, Susanne Schnittger, PhD, Martin Dugas, MD, Wolfgang Kern, MD, Claudia Haferlach, MD, Torsten Haferlach, MD

Blood (2010) 116 (21): 175.

https://doi.org/10.1182/blood.V116.21.175.175

Published: 2010

Journal Articles

The Interlaboratory RObustness of Next-Generation Sequencing (IRON) Study: Deep-Sequencing Investigating TET2 , CBL , and KRAS Mutations In 4464 Amplicons by An International Group Involving 8 Laboratories.

Blood (2010) 116 (21): 1665.

https://doi.org/10.1182/blood.V116.21.1665.1665

Published: 2010

Journal Articles

ChIP-on-Chip Analysis Identified HLXB9 as a Transcription Factor In Hematopoietic Cells and Alters the Expression of Genes Involved In Cell-Adhesion

Sarah Wildenhain, Christian Ruckert, Svenja Daschkey, Martin Dugas, MD, Julia Hauer, MD, Arndt Borkhardt, MD

Blood (2010) 116 (21): 2486.

https://doi.org/10.1182/blood.V116.21.2486.2486

Published: 2010

Journal Articles

The Pax5 Fusion Product Pax5-C20orf112 Causes Downregulation of Pre-B Cell Receptor Genes and Induces Differential Proliferation Patterns in B-Lymphoblastic Cell Lines.

Daniel Nowak, MD, Norihiko Kawamata, MD, PhD, Birte Niebuhr, PhD, Verena Nowak, Maximilian Mossner, Rahul R Nahar, Nils Heinrich Thoennissen, MD, Gabriela B. Iwanski, MD, Carol Stocking, PhD, Martin Dugas, MD, PhD, Wolf Karsten Hofmann, MD, PhD, Markus Müschen, MD, PhD, Phillip H Koeffler, MD, PhD

Blood (2009) 114 (22): 1284.

https://doi.org/10.1182/blood.V114.22.1284.1284

Published: 2009

Journal Articles

Next-Generation Sequencing (NGS) in CMML, MDS and AML Detects Molecular Mutations in Oncogenes and Allows the Identification of Balanced Chromosomal Abnormalities with Extraordinary Sensitivity and Specificity.

Vera Grossmann, MA, Alexander Kohlmann, PhD, Claudia Haferlach, MD, Hans-Ulrich Klein, MA, Martin Dugas, MD, Frank Dicker, PhD, Beray Kazak, Sonja Schindela, Susanne Schnittger, PhD, Wolfgang Kern, MD, Torsten Haferlach, MD

Blood (2009) 114 (22): 144.

https://doi.org/10.1182/blood.V114.22.144.144

Published: 2009

NARROW

DDX41 Is a Tumor Suppressor Gene Associated with Inherited and Acquired Mutations

Genetic Characterization Of Aplastic Anemia Patients By Targeted Sequencing

Identification Of Leukemia Suppressive Genes By Inducible Overexpression Of The DNA Methyltransferase DNMT3B During Leukemogenesis In Mice

The Clinical and Prognostic Influence Of Mutations In The Cohesin Complex In Acute Myeloid Leukemia

Landscape Of Genetic Lesions In 944 Patients With Myelodysplastic Syndromes

The Interlaboratory Robustness of Next-Generation Sequencing (IRON) Study Phase II: Deep-Sequencing Analyses of Hematological Malignancies Performed by an International Network Involving 26 Laboratories

A Specific DNA Methylation Pattern Is Associated with Delayed Leukemogenesis and Altered Response to Chemotherapeutic Treatment in an Inducible DNMT3b Expressing Mouse Model

Identification of the PML-RARα Associated DNA Methylome Using Reduced Representation Bisulfite Sequencing in Primary Patient Samples

Somatic Structural Variations in Pediatric High Hyperdiploid Acute Lymphoblastic Leukemia Revealed by Paired-End Parallel Sequencing

Whole Genome Amplification with Subsequent High Throughput Sequencing Allows Comprehensive Genome-Wide Analysis of Single Leukemic Cells

Histone H3 Methylation Mediates All- Trans -Retinoic Acid Responsiveness in Acute Myeloid Leukemia

Targeted Next-Generation Sequencing and Genome-Wide High-Resolution Copy Number DNA Arrays Allow the Identification of Five Novel RUNX1 Fusions In Hematological Malignancies.

Dominant-Negative Impact of PAX5/TEL on Downstream Targets of PAX5 and Essential Pre-B Cell Receptor Genes

Global Identification of Genomic Structural Variants In Childhood ETV6/RUNX1 ( TEL/AML1 ) Acute Lymphoblastic Leukemias by Mate-Pair Massively Parallel Sequencing.

Robust and Sensitive Detection of Insertions, Deletions and Point Mutations In CEBPA , a GC-Rich Content Gene, Using 454 Next-Generation Deep-Sequencing (NGS).

Targeted Next-Generation Sequencing (NGS) Enables a Broad Screening of 95 Molecular Mutations In a One-Step Approach and Detects Recurrent Mutations In AML with a Normal Karyotype In MYH11 and NOTCH1

The Interlaboratory RObustness of Next-Generation Sequencing (IRON) Study: Deep-Sequencing Investigating TET2 , CBL , and KRAS Mutations In 4464 Amplicons by An International Group Involving 8 Laboratories.

ChIP-on-Chip Analysis Identified HLXB9 as a Transcription Factor In Hematopoietic Cells and Alters the Expression of Genes Involved In Cell-Adhesion

The Pax5 Fusion Product Pax5-C20orf112 Causes Downregulation of Pre-B Cell Receptor Genes and Induces Differential Proliferation Patterns in B-Lymphoblastic Cell Lines.

Next-Generation Sequencing (NGS) in CMML, MDS and AML Detects Molecular Mutations in Oncogenes and Allows the Identification of Balanced Chromosomal Abnormalities with Extraordinary Sensitivity and Specificity.

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American Society of Hematology

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American Society of Hematology

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