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Marek Borský
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Journal Articles

Half: A Prospective Multi-Centre Phase II Clinical Trial Evaluating the Efficacy and Safety of Tyrosine Kinase Inhibitors' Discontinuation after Two-Step Dose Reduction in Patients with Chronic Myeloid Leukemia in Deep Molecular Remission

Daniela Žácková, Edgar Faber, Lukáš Stejskal, Michal Karas, Petra Bělohlávková, Hana Klamová, Olga Černá, Eduard Cmunt, Petra Čičátková, Lukáš Semerád, Tomáš Horňák, Anežka Kvetková, Jiřina Procházková, Jitka Rychlíčková, Radka Štěpánová, Adam Svobodník, Kateřina Machová Poláková, Ivana Ježíšková, Tomáš Jurček, Marek Borský, Ondřej Wiewiorka, Regina Demlová, Jiří Mayer
Journal: Blood
Blood (2021) 138 (Supplement 1): 3606.
https://doi.org/10.1182/blood-2021-146221
Published: 2021
Journal Articles

FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia

Vaclav Seda, Eva Vojackova, Laura Ondrisova, Lenka Kostalova, Sonali Sharma, Tomas Loja, Gabriela Mladonicka Pavlasova, Daniel Zicha, Marie Kudlickova Peskova, Jan Krivanek, Kvetoslava Liskova, Leos Kren, Vladimir Benes, Katerina Musilova Litzmanova, Marek Borsky, Jan Oppelt, Jan Verner, Sarka Pospisilova, Yvona Brychtova, Anna Panovska, Zhi Tan, Shuxing Zhang, Michael Doubek, Katerina Amruz Cerna, Jiri Mayer, Marek Mraz
Journal: Blood
Blood (2021) 138 (9): 758–772.
https://doi.org/10.1182/blood.2020008101
Published: 2021
Includes: Supplemental data
Journal Articles

miR-29 modulates CD40 signaling in chronic lymphocytic leukemia by targeting TRAF4: an axis affected by BCR inhibitors

Sonali Sharma, Gabriela Mladonicka Pavlasova, Vaclav Seda, Katerina Amruz Cerna, Eva Vojackova, Daniel Filip, Laura Ondrisova, Veronika Sandova, Lenka Kostalova, Pedro F. Zeni, Marek Borsky, Jan Oppelt, Kvetoslava Liskova, Leos Kren, Andrea Janikova, Sarka Pospisilova, Stacey M. Fernandes, Medhat Shehata, Laura Z. Rassenti, Ulrich Jaeger, Michael Doubek, Matthew S. Davids, Jennifer R. Brown, Jiri Mayer, Thomas J. Kipps, Marek Mraz
Journal: Blood
Blood (2021) 137 (18): 2481–2494.
https://doi.org/10.1182/blood.2020005627
Published: 2021
Includes: Supplemental data
Journal Articles

Rituximab Preferentially Eliminates BCR Signaling Proficient Chronic Lymphocytic Leukemia B Cells In Vivo

Gabriela Pavlasova, Marek Borsky, Katerina Musilova, Vaclav Seda, Katerina Cerna, Jitka Osickova, Eva Vojackova, Yvona Brychtova, Michael Doubek, Sarka Pospisilova, Jiri Mayer, Marek Mraz
Journal: Blood
Blood (2016) 128 (22): 2030.
https://doi.org/10.1182/blood.V128.22.2030.2030
Published: 2016
Journal Articles

Ibrutinib inhibits CD20 upregulation on CLL B cells mediated by the CXCR4/SDF-1 axis

Brief Report
Gabriela Pavlasova, Marek Borsky, Vaclav Seda, Katerina Cerna, Jitka Osickova, Michael Doubek, Jiri Mayer, Raffaele Calogero, Martin Trbusek, Sarka Pospisilova, Matthew S. Davids, Thomas J. Kipps, Jennifer R. Brown, Marek Mraz
Journal: Blood
Blood (2016) 128 (12): 1609–1613.
https://doi.org/10.1182/blood-2016-04-709519
Published: 2016
Includes: Supplemental data
Journal Articles

Microenvironmental Interactions up-Regulate CD20 Expression in CLL B Cells through the CXCR4/SDF-1 Axis: Implications for CD20-Targeting Antibodies and the Use of BCR-Inhibitors in Combination

Gabriela Pavlasova, MSc, Vaclav Seda, MSc, Marek Borsky, MSc., Katerina Cerna, MSc, Jitka Osickova, PhD, Jiri Mayer, Prof., MD, Sarka Pospisilova, Matthew S. Davids, MD, Jennifer R. Brown, MD PhD, Marek Mraz, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4124.
https://doi.org/10.1182/blood.V126.23.4124.4124
Published: 2015
Journal Articles

Single Cell Analysis of IG Genes in CLL: Cases with Multiple IGH Rearrangements Are Constituted of Several Independent Clones Even When Indistinguishable By Flow Cytometry

Kamila Brazdilova, MSc., Karla Plevova, PhD, Hana Skuhrova Francova, MSc, Helena Kockova, MSc, Magdalena Chmelikova, MSc, Marek Borsky, MSc., Katerina Burckova, MSc, Barbara Kantorova, MSc, Boris Tichy, PhD, Hana Skabrahova, Yvona Brychtova, PhD, MD, Jiri Mayer, Prof, MD PhD, Michael Doubek, MD PhD, Sarka Pospisilova, Prof.
Journal: Blood
Blood (2015) 126 (23): 4139.
https://doi.org/10.1182/blood.V126.23.4139.4139
Published: 2015
Journal Articles

Single Cell Analysis Proves the Coexistence of NOTCH1 and TP53 Mutations within the Same Cancer Cells in Patients with Chronic Lymphocytic Leukemia

Barbara Kantorova, MSc., Jitka Malcikova, PhD, Kamila Brazdilova, MSc., Marek Borsky, MSc., Karla Plevova, PhD, Jana Smardova, Prof., Martin Trbusek, PhD, Yvona Brychtova, PhD, MD, Michael Doubek, Prof., MD, Jiri Mayer, Prof., MD, Sarka Pospisilova, Prof.
Journal: Blood
Blood (2015) 126 (23): 2913.
https://doi.org/10.1182/blood.V126.23.2913.2913
Published: 2015
Journal Articles

Prognostic Impact of NOTCH1 Hotspot Mutation in TP53 -Mutated Patients with Chronic Lymphocytic Leukemia

Barbara Kantorova, M.S., Jitka Malcikova, PhD, Veronika Navrkalova, M.S., PhD, Jana Smardova, Prof., MD PhD, Kamila Brazdilova, M.S., Karla Plevova, M.S., PhD, Eva Diviskova, M.S., Marek Borsky, M.S., Sarka Pavlova, M.S., PhD, Nikola Tom, M.S., Karol Pal, M.S., Martin Trbusek, Dr., PhD, Alexandra Oltova, Dr., Yvona Brychtova, MD PhD, Michael Doubek, Prof., MD PhD, Jiri Mayer, Prof., MD PhD, Sarka Pospisilova, Prof., Dr., PhD
Journal: Blood
Blood (2014) 124 (21): 3283.
https://doi.org/10.1182/blood.V124.21.3283.3283
Published: 2014
Journal Articles

MicroRNA-650 expression is influenced by immunoglobulin gene rearrangement and affects the biology of chronic lymphocytic leukemia

Brief Report
Marek Mraz, Dasa Dolezalova, Karla Plevova, Katerina Stano Kozubik, Veronika Mayerova, Katerina Cerna, Katerina Musilova, Boris Tichy, Sarka Pavlova, Marek Borsky, Jan Verner, Michael Doubek, Yvona Brychtova, Martin Trbusek, Ales Hampl, Jiri Mayer, Sarka Pospisilova
Journal: Blood
Blood (2012) 119 (9): 2110–2113.
https://doi.org/10.1182/blood-2011-11-394874
Published: 2012
Includes: Supplemental data
Journal Articles

Detail Characterization of 22q11 Deletion and Mir-650 Role in CLL Patients.

Marek Mraz, MD, MSC., Karla Malinova, Sarka Pavlova, Boris Tichy, Katerina Stano Kozubik, Jitka Malcikova, Marek Borsky, Jan Verner, Michael Doubek, Yvona Brychtova, Martin Trbusek, Jiri Mayer, MD, Sarka Pospisilova
Journal: Blood
Blood (2009) 114 (22): 1231.
https://doi.org/10.1182/blood.V114.22.1231.1231
Published: 2009
Journal Articles

Detection and Treatment of Molecular Relapse in Acute Myeloid Leukemia with RUNX1, CBFB or MLL Gene Translocations. Frequent Quantitative Monitoring of Molecular Markers in Different Compartments and Correlation with WT1 Gene Expression.

Michael Doubek, MD, PhD, Ivo Palasek, MD, Zdenek Pospisil, PhD, Sona Struncova, PhD, Dana Dvorakova, PhD, Marek Borsky, PhD, Martin Klabusay, PhD, Yvona Brychtova, MD, Marta Krejci, MD, PhD, Jiri Mayer, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 4356.
https://doi.org/10.1182/blood.V110.11.4356.4356
Published: 2007
Journal Articles

Detection of Molecular Relapse of AML by Very Frequent Quantitative Monitoring of Different Molecular Markers (Fusion Transcripts and WT1) in Different Compartments (Peripheral Blood-PB, Bone Marrow-BM, and Selected CD34+ Bone Marrow Cells) and Its Treatment with Chemotherapy or Gemtuzumab Ozogamicin.

Jiri Mayer, Ivo Palasek, Zdenek Pospisil, Sona Struncova, Dana Dvorakova, Marek Borsky, Martin Klabusay, Michael Doubek, Yvona Brychtova, Zdenek Racil
Journal: Blood
Blood (2006) 108 (11): 4481.
https://doi.org/10.1182/blood.V108.11.4481.4481
Published: 2006