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Marcel R. M. van den Brink, MD PhD
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Journal Articles

The Disease Risk Index Predicts Outcomes Including Relapse and Survival in CD34-Selected Allogeneic HCT for Acute Leukemia and Myelodysplastic Syndrome

Christina Cho, MD, Patrick Hilden, MS, Jonathan U. Peled, MD PhD, Scott T. Avecilla, MD PhD, Pere Barba, MD, Juliet N. Barker, MBBS (Hons), Hugo R. Castro-Malaspina, MD, Sergio A. Giralt, MD, Ann A. Jakubowski, MD PhD, Guenther Koehne, MD PhD, Richard C. Meagher, PhD, Molly A. Maloy, MS, Richard J. O'Reilly, MD, Esperanza B. Papadopoulos, MD, Doris M. Ponce, MD, Marcel R. M. van den Brink, MD PhD, James W. Young, MD, Miguel-Angel Perales, MD
Journal: Blood
Blood (2016) 128 (22): 3498.
https://doi.org/10.1182/blood.V128.22.3498.3498
Published: 2016
Journal Articles

Genomic Profiling Combining DNA and RNA Analysis of 112 Formalin-Fixed Paraffin-Embedded Diffuse Large B Cell Lymphoma Specimens Identifies a High Frequency of Clinically Relevant Genomic Alterations

Andrew M. Intlekofer, MD PhD, Patrick Hilden, MS, Venkatraman E. Seshan, PhD, Amanda R. Copeland, MSN, Ross L. Levine, MD, Andrew D. Zelenetz, MD PhD, Julie Teruya-Feldstein, MD, Ahmet Dogan, MD PhD, Maria Lia Palomba, MD, Craig H. Moskowitz, MD, Marcel R. M. van den Brink, MD PhD, Kristina M. Knapp, BS, Janine D. Pichardo, BS, Kristina W. Brennan, BS, Geneva Young, BS, Jie He, PhD, Michelle K. Nahas, PhD, Roman Yelensky, PhD, Geoff A. Otto, PhD, Doron Lipson, PhD, Philip J. Stephens, PhD, Vincent A. Miller, MD, Anas Younes, MD
Journal: Blood
Blood (2014) 124 (21): 704.
https://doi.org/10.1182/blood.V124.21.704.704
Published: 2014
Journal Articles

Genomic Analysis of Serial Samples from CLL Patients Identifies Clonal Events Associated with Disease Progression

Jeffrey R Gardner, BS, MBA, Michelle Nahas, PhD, Jie He, PhD, Shlomzion Aumann, Mithat Gonen, Minal Patel, Kristina M. Knapp, BS, Maria Lia Palomba, MD, Roman Yelensky, PhD, Amy L Donahue, MS, Geoff Otto, PhD, Maria Arcila, MD, Nicole Lamanna, Mark G. Frattini, MD PhD, Ahmet Dogan, MD PhD, Jae H Park, MD, Doron Lipson, PhD, Martin S. Tallman, MD, Ross L. Levine, MD, Philip J. Stephens, PhD, Marcel R. M. van den Brink, MD PhD, Mark L Heaney, MD PhD, Vincent A. Miller, MD, Andrew D. Zelenetz, MD PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2014) 124 (21): 1954.
https://doi.org/10.1182/blood.V124.21.1954.1954
Published: 2014
Journal Articles

Clinical Utility of Comprehensive Profiling of Genomic Alterations in Hematologic Malignancies

Jie He, PhD, Jose A. Bufill, MD, Michelle K. Nahas, PhD, Kai Wang, MDPhD, Lauren E Young, MS, Kristina M. Knapp, Kristina W. Brennan, BS, Amy L Donahue, MS, Geneva Young, BS, Jeffrey S Ross, MD, Deborah Morosini, MD, Marcel R. M. van den Brink, MD PhD, Omar Abdel-Wahab, MD, Raajit K. Rampal, MD PhD, Andrew M. Intlekofer, MD PhD, Ahmet Dogan, MD PhD, Scott Armstrong, MD PhD, Roman Yelensky, PhD, Geoff Otto, PhD, Doron Lipson, PhD, Philip J. Stephens, PhD, Vincent A. Miller, MD, Ross L. Levine, MD
Journal: Blood
Blood (2014) 124 (21): 1072.
https://doi.org/10.1182/blood.V124.21.1072.1072
Published: 2014
Journal Articles

IL-22 Administration Decreases Intestinal Gvhd Pathology, Increases Intestinal Stem Cell Recovery, and Enhances Immune Reconstitution Following Allogeneic Hematopoietic Transplantation

Anna M Mertelsmann, Jarrod A Dudakov, PhD, Enrico Velardi, PhD, Guoqiang Hua, PhD, Fabiana M Kreines, BS, Emily R Levy, BS, Margaret O'Connor, Odette M Smith, BA, Richard Kolesnick, MD, Marcel R. M. van den Brink, MD, PhD, Alan M Hanash, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 290.
https://doi.org/10.1182/blood.V122.21.290.290
Published: 2013
Journal Articles

Extensive High-Depth Sequencing Of Longitudinal CLL Samples Identifies Frequent Mutations In MAP Kinase Signaling and Novel Mutations Activating Notch and Beta-Catenin

Jeffrey R Gardner, MBA, Michelle K. Nahas, PhD, Jie He, PhD, Minal Patel, Kristina M. Knapp, BS, M. Lia Palomba, MD, Roman Yelensky, PhD, Amy L Donahue, MS, Geoff A. Otto, PhD, Maria Arcila, MD, Ahmet Dogan, MD, PhD, Jae H Park, MD, Andrew D. Zelenetz, MD, PhD, Doron Lipson, PhD, Martin S. Tallman, MD, Ross L. Levine, MD, Philip J. Stephens, PhD, Marcel R. M. van den Brink, MD, PhD, Vincent A. Miller, MD, Mark L Heaney, MD, PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2013) 122 (21): 2858.
https://doi.org/10.1182/blood.V122.21.2858.2858
Published: 2013
Journal Articles

Profiling Genomic Alterations Of Diffuse Large B-Cell Lymphoma (DLBCL) At Diagnosis, Relapse, and Transformation, Using a Novel Clinical Diagnostic Targeted Sequencing Platform

Andrew M. Intlekofer, MD, PhD, Venkatraman E. Sheshan, PhD, Ross L. Levine, MD, Andrew D. Zelenetz, MD, PhD, Julie Teruya-Feldstein, MD, Ahmet Dogan, MD, PhD, Maria Lia Palomba, MD, Craig H. Moskowitz, MD, Marcel R. M. van den Brink, MD, PhD, Kristina M. Knapp, BS, Amanda R. M. Copeland, MSN, Janine D. Pichardo, BS, Kristina W. Brennan, BS, Geneva Young, BS, Jie He, PhD, Michelle K. Nahas, PhD, Roman Yelensky, PhD, Geoff A. Otto, PhD, Doron Lipson, PhD, Philip J. Stephens, PhD, Vincent A. Miller, MD, Anas Younes, MD
Journal: Blood
Blood (2013) 122 (21): 1761.
https://doi.org/10.1182/blood.V122.21.1761.1761
Published: 2013
Journal Articles

Sex Steroid Blockade Enhances Thymopoiesis By Modulating Notch Signaling

Enrico Velardi, PhD, Jennifer J Tsai, M.D., Amanda M. Holland, PhD, Natalie V Singer, BS, Mallory L West, BS, Odette M Smith, BA, Lauren F. Young, BS, Fabiana M Kreines, BS, Emily R Levy, BS, Richard Boyd, PhD, Marcel R. M. van den Brink, MD, PhD, Jarrod A Dudakov, PhD
Journal: Blood
Blood (2013) 122 (21): 291.
https://doi.org/10.1182/blood.V122.21.291.291
Published: 2013
Journal Articles

Identification Of Actionable Genomic Alterations In Hematologic Malignancies By a Clinical Next Generation Sequencing-Based Assay

Doron Lipson, PhD, Michelle K Nahas, PhD, Geoff A. Otto, PhD, Roman Yelensky, PhD, Omar Abdel-Wahab, MD, Kai Wang, MD PhD, Jie He, PhD, Andrew M. Intlekofer, MD, PhD, Raajit K. Rampal, M.D., Ph.D., Timothy A Brennan, MS, Kristina M. Knapp, BS, Kristina W Brennan, BS, Geneva Young, BS, Amy L Donahue, MS, Eric M Sanford, BS, Joel R Greenbowe, BS, Garrett M Frampton, PhD, Alex Fichtenholtz, PhD, Lauren E Young, MS, Rachel L Erlich, PhD, Alex Parker, PhD, David Klimstra, Ahmet Dogan, MD, PhD, Jeffrey S Ross, MD, Scott A. Armstrong, MD, PhD, Philip J. Stephens, PhD, Marcel R. M. van den Brink, MD, PhD, Vincent A. Miller, MD, Ross L. Levine, MD
Journal: Blood
Blood (2013) 122 (21): 230.
https://doi.org/10.1182/blood.V122.21.230.230
Published: 2013
Journal Articles

The T Cell Cytolytic Molecules Fas Ligand and TRAIL, the Trafficking Molecules CCR9, β7 Integrin and PSGL-1, and the Immune Modulating Molecules OX40, CEACAM1, and CTLA4 Are Required for Thymic Graft-Versus-Host Disease

Il-Kang Na, MD, Sydney X. Lu, Gabrielle L. Goldberg, PhD, Daniel Daniel Hirschhorn-Cymerman, PhD, Christopher G. King, Odette M. Smith, David Suh, Uttam Rao, Nury Yim, Amanda M. Holland, Olaf Penack, MD, Robert R. Jenq, MD, Arnab Ghosh, MD, PhD, Laura Teisch, Simon Meykler, Janine Lin, Alejandro Sepulveda, PhD, Taha Merghoub, PhD, Alan Houghton, MD, Marcel R. M. van den Brink, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 65.
https://doi.org/10.1182/blood.V112.11.65.65
Published: 2008