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Journal Articles

Bridging Pediatric B-Cell Acute Lymphoblastic Leukemia (ALL) Patients to CAR-T Cell Therapy: A National Perspective

Gustavo De Oliveira Canedo, Macarena Oporto Espuelas, Saskia Burridge, Priti Mehta, Orpheas Iosifidis, Denise Bonney, Kelly Watts, Geoff Shenton, Katarzyna Jalowiec, Maeve O'Reilly, Claire Roddie, Katherine Clesham, Jack Bartram, Robert Chiesa, Giovanna Lucchini, Vesna Pavasovic, Anupama Rao, Kanchan Rao, Juliana Silva, Sujith Samarasinghe, Ajay Vora, David Marks, Persis Jal Amrolia, Rachael Hough, Sara Ghorashian
Journal: Blood
Blood (2024) 144 (Supplement 1): 4206.
https://doi.org/10.1182/blood-2024-200239
Published: 2024
Journal Articles

Single Cell Multimodal Framework Identifies CD84 As a Leukaemic Stem Cell Target in Paediatric AML

Macarena Oporto Espuelas, Sina Kanannejad, Ilaria Marina Michelozzi, Eduardo Gomez Castaneda, Theodoros Xenakis, Efstratios Kirtsios, Hannah Macpherson, Jack Bartram, Rebecca Thomas, Edoardo Giacopuzzi, Soumick Chatterjee, Filippo Martignano, Sergi Castellano, Persis Jal Amrolia, Alice Giustacchini
Journal: Blood
Blood (2024) 144 (Supplement 1): 4317.
https://doi.org/10.1182/blood-2024-204084
Published: 2024
Journal Articles

CD19/CD22 targeting with cotransduced CAR T cells to prevent antigen-negative relapse after CAR T-cell therapy for B-cell ALL

Clinical Trials & Observations Brief Report
Sara Ghorashian, Giovanna Lucchini, Rachel Richardson, Kyvi Nguyen, Craig Terris, Aleks Guvenel, Macarena Oporto-Espuelas, Jenny Yeung, Danielle Pinner, Jan Chu, Lindsey Williams, Ka-Yuk Ko, Chloe Walding, Kelly Watts, Sarah Inglott, Rebecca Thomas, Christopher Connor, Stuart Adams, Emma Gravett, Kimberly Gilmour, Alka Lal, Sangeetha Kunaseelan, Bilyana Popova, Andre Lopes, Yenting Ngai, Allan Hackshaw, Evangelia Kokalaki, Milena Balasch Carulla, Khushnuma Mullanfiroze, Arina Lazareva, Vesna Pavasovic, Anupama Rao, Jack Bartram, Ajay Vora, Robert Chiesa, Juliana Silva, Kanchan Rao, Denise Bonney, Robert Wynn, Martin Pule, Rachael Hough, Persis J. Amrolia
Journal: Blood
Blood (2024) 143 (2): 118–123.
https://doi.org/10.1182/blood.2023020621
Published: 2024
Includes: Supplemental data
Journal Articles

Systematic Intention to Treat Analysis of Real-World Outcomes in Children and Young Adults Receiving Tisagenlecleucel: From Elegibility through Treatment Failure

Macarena Oporto Espuelas, Saskia Burridge, Denise Bonney, Kelly Watts, Claire Roddie, Maeve A O'Reilly, Geoff Shenton, John A Snowden, Caroline Furness, Katarzyna Aleksandra Aleksandra Jalowiec, Lorna Neill, Katherine Clesham, Emma Nicholson, Anna Castleton, Amit Patel, Caroline Besley, Robert F Wynn, Ajay Vora, David I. Marks, Lindsay George, Ben Uttenthal, Sridhar Chaganti, Michelle Cummins, Persis J Amrolia, Rachael E Hough, Sara Ghorashian
Journal: Blood
Blood (2022) 140 (Supplement 1): 2408–2410.
https://doi.org/10.1182/blood-2022-162863
Published: 2022
Journal Articles

Dual Antigen Targeting with Co-Transduced CD19/22 CAR T Cells May Prevent Antigen-Negative Relapse after CAR T Cell Therapy for Relapsed/Refractory ALL

Sara Ghorashian, Giovanna Lucchini, Rachel Richardson, Kyvi Nguyen, Craig Terris, Macarena Oporto-Espuelas, Jenny Yeung, Danielle Pinner, Jan Chu, Lindsey Williams, Ka-yuk Ko, Chloe Walding, Kelly Watts, Sarah Inglott, Stuart Adams, Emma Gravett, Kimberly Gilmour, Alka Lal, Sangeetha Kunaseelan, Bilyana Popova, Andre Lopes, Yenting Ngai, Evangelia K Kokalaki, Milena Balasch Carulla, Khushnuma Mullanfiroze, Arina Lazareva, Vesna Pavasovic, Anupama Rao, Jack Bartram, Ajay Vora, Robert Chiesa, Juliana Silva, Kanchan Rao, Katherine Clesham, Denise Bonney, Robert F Wynn, Martin Pule, Rachael E Hough, Persis J Amrolia
Journal: Blood
Blood (2022) 140 (Supplement 1): 10352–10354.
https://doi.org/10.1182/blood-2022-164879
Published: 2022
Journal Articles

ALL Maintenance Treatment for Early Loss of B-Cell Aplasia after Tisagenlecleucel Therapy

Maria Gabelli, Macarena Oporto Espuelas, Denise Bonney, Saskia Burridge, Susan Farish, Khushnuma Mullanfiroze, Arina Lazareva, Sujith Samarasinghe, Philip Ancliffe, Ajay Vora, Jack Bartram, Emma Hedges, Kirsty Ware, Lindsey Young, Chiara Cugno, Lenka Chenchara, Juliana Silva, Oana Mirci-Danicar, Lynne Riley, Vesna Pavasovic, Anupama Rao, Paul Veys, Giovanna Lucchini, Robert Chiesa, Kanchan Rao, Persis J Amrolia, Sara Ghorashian
Journal: Blood
Blood (2021) 138 (Supplement 1): 3859.
https://doi.org/10.1182/blood-2021-152344
Published: 2021