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Journal Articles

Human Gene Therapy Optimized for the Platelet Bleeding Disorder Glanzmann Thrombasthenia

Juan Fang, Matthew Hogenauer, Aoife M. Roche, Sevasti B. Koukouritaki, Lily M. Du, Huiqing Xu, John Everett, Frederic D. Bushman, Myriam Armant, Peiman Hematti, David A. Wilcox

Blood (2024) 144 (Supplement 1): 5409.

https://doi.org/10.1182/blood-2024-199243

Published: 2024

Journal Articles

Gene Therapy Expressing Platelet-Derived Factor VIII for Correction of Hemophilia Α with a History of Inhibitors

David A. Wilcox, Myriam Armant, Lynn Malec, Qizhen Shi, Bryon D. Johnson, Huiqing Xu, Lily M. Du, Lisa J. Duffy, Frederic D. Bushman, James H. Jerkins, Peiman Hematti, Ruta Brazauskas, Shawn M. Jobe, Parameswaran N. Hari, Mary Eapen

Blood (2023) 142 (Supplement 1): 2249.

https://doi.org/10.1182/blood-2023-172845

Published: 2023

Journal Articles

De Novo Synthesis & Storage of Human Factor VIII In Platelets Reduces Bleeding In Canine Hemophilia A

Lily M. Du, MD, Helen W.G. Franck, BS, Elizabeth P. Merricks, PhD, Paquita Nurden, MD, Eric S. Jensen, DVM, Sandra L. Haberichter, PhD, Troy B. Hawkins, PhD, Paula M. Jacobi, BS, Juan Fang, MD, Timothy C. Nichols, MD, Sevasti B. Koukouritaki, PhD, Qizhen Shi, MD, PhD, Robert R. Montgomery, MD, Kenneth Cornetta, MD, Alan T. Nurden, PhD, David A. Wilcox, PhD

Blood (2010) 116 (21): 2198.

https://doi.org/10.1182/blood.V116.21.2198.2198

Published: 2010

Journal Articles

Platelet-Targeted Expression of Human BDD-FVIII Reduces Bleeding in Canine Hemophilia A.

Lily M. Du, MS, MD, Timothy C. Nichols, MD, Sandra L. Haberichter, PhD, Paula M. Jacobi, Eric S. Jensen, DVM, Juan Fang, MD, Qizhen Shi, MD, PhD, Robert R. Montgomery, MD, David A. Wilcox, PhD

Blood (2009) 114 (22): 691.

https://doi.org/10.1182/blood.V114.22.691.691

Published: 2009

Journal Articles

Platelet-Targeted Expression of Coagulation Factor VIII (FVIII) Shows Efficacy for Using the Dog as a Large Animal Model for Gene Therapy of Hemophilia a

David A. Wilcox, PhD, Lily M. Du, MS, MD, Sandra L. Haberichter, PhD, Paula M. Jacobi, Juan Fang, MD, Eric S. Jensen, DVM, Qizhen Shi, MD, PhD, Robert R. Montgomery, MD

Blood (2008) 112 (11): 3525.

https://doi.org/10.1182/blood.V112.11.3525.3525

Published: 2008

Journal Articles

Intravenous Immunoglobulin (IVIG) Diminishes Immune-Mediated Clearance of Platelets Expressing an Integrin αIIbβ3 Transgene Product That Restores Hemostasis in a Canine Model for Glanzmann Thrombasthenia.

Juan Fang, MD, Eric S. Jensen, DVM, Lily M. Du, MD,Ms, Mary K. Boudreaux, DVM,PhD, David A. Wilcox, PhD

Blood (2006) 108 (11): 3263.

https://doi.org/10.1182/blood.V108.11.3263.3263

Published: 2006

Journal Articles

Phenotypic Correction of a Canine Model for Glanzmann Thrombasthenia Demonstrates Efficacy for Using Platelets To Deliver Therapeutics at the Site of Vascular Injury.

David A. Wilcox, PhD, Juan Fang, Lily M. Du, Mary K. Boudreaux, PhD, DVM

Blood (2005) 106 (11): 3045.

https://doi.org/10.1182/blood.V106.11.3045.3045

Published: 2005

Journal Articles

Therapeutic expression of the platelet-specific integrin, αIIbβ3, in a murine model for Glanzmann thrombasthenia

Juan Fang, Kairbaan Hodivala-Dilke, Bryon D. Johnson, Lily M. Du, Richard O. Hynes, Gilbert C. White, II, David A. Wilcox

Blood (2005) 106 (8): 2671–2679.

https://doi.org/10.1182/blood-2004-12-4619

Published: 2005

Journal Articles

Single-chain antibody fragments derived from a human synthetic phage-display library bind thrombospondin and inhibit sickle cell adhesion

Nicholas A. Watkins, Lily M. Du, J. Paul Scott, Willem H. Ouwehand, Cheryl A. Hillery

Blood (2003) 102 (2): 718–724.

https://doi.org/10.1182/blood-2002-11-3497

Published: 2003

Journal Articles

The accumulation of p53 abnormalities is associated with progression of mucosa-associated lymphoid tissue lymphoma

M Du, H Peng, N Singh, PG Isaacson, L Pan

Blood (1995) 86 (12): 4587–4593.

https://doi.org/10.1182/blood.V86.12.4587.bloodjournal86124587

Published: 1995

NARROW

Human Gene Therapy Optimized for the Platelet Bleeding Disorder Glanzmann Thrombasthenia

Gene Therapy Expressing Platelet-Derived Factor VIII for Correction of Hemophilia Α with a History of Inhibitors

De Novo Synthesis & Storage of Human Factor VIII In Platelets Reduces Bleeding In Canine Hemophilia A

Platelet-Targeted Expression of Human BDD-FVIII Reduces Bleeding in Canine Hemophilia A.

Platelet-Targeted Expression of Coagulation Factor VIII (FVIII) Shows Efficacy for Using the Dog as a Large Animal Model for Gene Therapy of Hemophilia a

Intravenous Immunoglobulin (IVIG) Diminishes Immune-Mediated Clearance of Platelets Expressing an Integrin αIIbβ3 Transgene Product That Restores Hemostasis in a Canine Model for Glanzmann Thrombasthenia.

Phenotypic Correction of a Canine Model for Glanzmann Thrombasthenia Demonstrates Efficacy for Using Platelets To Deliver Therapeutics at the Site of Vascular Injury.

Therapeutic expression of the platelet-specific integrin, αIIbβ3, in a murine model for Glanzmann thrombasthenia

Single-chain antibody fragments derived from a human synthetic phage-display library bind thrombospondin and inhibit sickle cell adhesion

The accumulation of p53 abnormalities is associated with progression of mucosa-associated lymphoid tissue lymphoma

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American Society of Hematology

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American Society of Hematology

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