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Journal Articles

IDH1/2-mutant clonal hematopoiesis: A novel driver of autoinflammatory disease

Free
Griffen Mustion, Flore Castellan, John Cole, Mei-Kay Wong, Kimberly Johansson, Scott Goldberg, Yazan Madanat, Namrata Chandhok, Abhay Singh, David Sallman, Jane Churpek, Curtis Lachowiez, Jennifer Yannucci, Luke Fletcher, Matthew Schwede, Amber Afzal, Yael Kusne, Alejandro Marinos Velarde, Alexander Coltoff, Rickey Myhand, Akriti Jain, Kiran Vij, Rosalyn Marar, Hannah Mitchell, Maria Stoentcheva, Giulia Petrone, Kyra Ddungu, Hannah Hartman, Ryan Monahan, Karen Vandervort, Tibor Kovacsovics, Hetty Carraway, Tian Zhang, Stephen Chung, Geoffrey Uy, Eytan Stein, Devendra Hiwase, Matthew Walter, Mrinal Patnaik, David Beck, Kelly Bolton
Journal: Blood
Blood (2025) 146 (Supplement 1): 3169.
https://doi.org/10.1182/blood-2025-3169
Published: 2025
Journal Articles

Ivosidenib leads to durable responses in IDH1 mutated clonal cytopenias of undetermined significance: A phase II decentralized clinical trial

Free
Kelly Bolton, Yazan Madanat, Namrata Chandhok, David Sallman, Abhay Singh, Kiran Vij, Jane Churpek, Luke Fletcher, Matthew Schwede, Curtis Lachowiez, Amber Afzal, Rickey Myhand, Alejandro Marinos Velarde, Rosalyn Marar, Tibor Kovacsovics, Hannah Mitchell, Maria Stoentcheva, Kimberly Johansson, Giulia Petrone, Kyra Ddungu, John Cole, Hannah Hartman, Ryan Monahan, Karen Vandervort, Mrinal Patnaik, Akriti Jain, Matthew Walter, Yael Kusne, Alexander Coltoff, Hetty Carraway, Jennifer Yannucci, Tian Zhang, Stephen Chung, Geoffrey Uy, Eytan Stein
Journal: Blood
Blood (2025) 146 (Supplement 1): 635.
https://doi.org/10.1182/blood-2025-635
Published: 2025
Journal Articles

Best Practices to Overcoming Challenges in Initiating Venetoclax for Patients with Chronic Lymphocytic Leukemia: Results from a United States Community-Based Healthcare Practitioner Survey

Free
Ryan Jacobs, Luke Fletcher, Andrew Rettew, Sophia S Li, Katherine Eakle, Mina Shahkarami, Rongrong Wang, Tu My To, Susan D Mathias, Isabella Manigault, John M. Burke
Journal: Blood
Blood (2024) 144 (Supplement 1): 2268.
https://doi.org/10.1182/blood-2024-198466
Published: 2024
Journal Articles

Real-World Baseline Characteristics and Preliminary Outcomes in Patients with Myelofibrosis Treated with Momelotinib in the US Community Oncology Practice Setting

Free
Luke Fletcher, Nicole Niehoff, Sneha Sura, Tom Liu, Karen Todoroff, William Zhang, Ira Zackon
Journal: Blood
Blood (2024) 144 (Supplement 1): 2430.
https://doi.org/10.1182/blood-2024-199834
Published: 2024
Journal Articles

Consolidation of High-Risk Acute Promyelocytic Leukemia (APL) in Community Infusion Centers: A Single Center Experience

Free
Selina (Qiuying) Liu, Luke Fletcher, Elie Traer
Journal: Blood
Blood (2022) 140 (Supplement 1): 11708–11709.
https://doi.org/10.1182/blood-2022-159810
Published: 2022
Journal Articles

Comparative Outcomes and Molecular Response Predictors of IDH1/2-Mutated Adult Acute Myeloid Leukemia (AML) Patients (Pts) after Frontline Treatment with Intensive Induction Chemotherapy (IC), Targeted Inhibitors, or Hypomethylating Agents (HMA) (Alliance)

Free
Uma Borate, Prapti A. Patel, Chetasi Talati, Jessica Kohlschmidt, Michael P. Ozga, Yazan F. Madanat, Luke Fletcher, Ravi Patel, Krzysztof Mrózek, Deedra Nicolet, Akriti G Jain, Virginia Olivia Volpe, Fei Yang, Richard D. Press, Daniel Jones, James S. Blachly, Christopher J. Walker, Andrew J Carroll, Guido Marcucci, Maria R. Baer, William Blum, Bayard L. Powell, Jonathan E Kolitz, Richard A. Larson, Richard M. Stone, John C. Byrd, Alice S. Mims, Kendra Sweet, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2021) 138 (Supplement 1): 226.
https://doi.org/10.1182/blood-2021-152838
Published: 2021
Journal Articles

Dynamic Regulation of Histone Acetylation By Nuclear Proteolysis Controls Cell Cycle Gene Expression and Chromosome Integrity in Multiple Myeloma

Free
Laure Maneix, PhD, Polina Iakova, M.S., Shannon Moree, B.A., Luke Fletcher, MD, Premal Lulla, MBBS, Sarvari Venkata Yellapragada, M.B.B.S., MD, Andre Catic, MD, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1753.
https://doi.org/10.1182/blood.V130.Suppl_1.1753.1753
Published: 2017
Journal Articles

Development of a Small-Molecule Inhibitor Screen to Rapidly Identify Key Signaling Pathways in Leukemogenesis.

Free
Jeffrey W Tyner, PhD, Luke Fletcher, Wayne Yang, Stephen T Oh, MD, PhD, Jason R. Gotlib, MD, Michael WN Deininger, MD, Brian J. Druker, MD, Marc Loriaux, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 708.
https://doi.org/10.1182/blood.V114.22.708.708
Published: 2009