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Leon Tshilolo
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Journal Articles

Hydroxyurea Treatment Reduces Infection Rates in African Children with Sickle Cell Anemia

Thomas N. Williams, Teresa S. Latham, George A. Tomlinson, Peter Olupot-Olupot, Brigida Santos, Leon Tshilolo, Adam C. Lane, Banu Aygun, Susan E. Stuber, Luke R. Smart, Russell E. Ware
Journal: Blood
Blood (2024) 144 (Supplement 1): 545.
https://doi.org/10.1182/blood-2024-210347
Published: 2024
Journal Articles

Growth and Puberty in African Children with Sickle Cell Anemia Treated with Hydroxyurea

Philippe Backeljauw, George A. Tomlinson, Luke R. Smart, Leon Tshilolo, Thomas N. Williams, Brigida Santos, Peter Olupot-Olupot, Susan E. Stuber, Adam C. Lane, Teresa S. Latham, Russell E. Ware
Journal: Blood
Blood (2024) 144 (Supplement 1): 544.
https://doi.org/10.1182/blood-2024-205848
Published: 2024
Journal Articles

Analysis of the Pilot Study of the International Hemoglobinopathy Research Network (INHERENT)

Natasha Archer, Coralea Stephanou, Maria Xenophontos, Leon Tshilolo, Franck Nzengu Lukusa, Sylvain Fazili, Obiageli E Nnodu, Maxwell Nwegbu, Ali Dahiru Waziri, Sani Awwalu, Soteroula Christou, Irene Savvidou, Ann Rekleiti, Anna Minaidou, Michail D Diamantidis, Norafiza Mohd Yasin, Norasmidar Abdul Aziz, Veena Selvaratnam, Ezalia Esa, Andreas Glenthoej, Sophia Delicou, Livingstone Gayus Dogara, Maria Dimopoulou, Raja Sabudin, Norunaluwar Jalil, C-Khai Loh, Sie-Chong Doris Lau, Bin Alwi Zilfalil, Norsarwany Mohamad, Syahiran Mohammad, Ahmad-Zafrullahafham Ahmad-Fakri, Halim-Fikri Hashim, Morohuntodun O. Oni, Antonieta Lukangu, Ligia Alves, Miguel Brito, Viviana Giannuzzi, Fedele Bonifazi, Kyriaki Michailidou, Sotiroula Chatzimatthaiou, Carsten Lederer, Petros Kountouris
Journal: Blood
Blood (2024) 144 (Supplement 1): 1132.
https://doi.org/10.1182/blood-2024-200469
Published: 2024
Journal Articles

Availability and Cost of Basic Drugs for Sickle Cell Disease in 13 African Countries

Gladys Kelly Keza, Dapa Aly Diallo, Ibrahima Diagne, Mariane de Montalembert, Anne Corbasson, Françoise Bernaudin, Brigitte Ranque, Binta Coulibaly, Galacteros Frederic, Saliou Diop, Constant Vodouhé, Olivier Hermine, Agnès Lainé, Eléonor Kafando, Ahoefa Vovor, Sébastien Jan, Leon Tshilolo, Robert Hue, Jean-Benoit Arlet
Journal: Blood
Blood (2023) 142 (Supplement 1): 1152.
https://doi.org/10.1182/blood-2023-188652
Published: 2023
Journal Articles

Hydroxyurea Dose Optimization Is Safe and Improves Outcomes for Children with Sickle Cell Anemia Living in Sub-Saharan Africa: The Reach Experience

Banu Aygun, Adam C. Lane, Luke R. Smart, Leon Tshilolo, Thomas N. Williams, Peter Olupot-Olupot, Brigida Santos, Susan E. Stuber, George A. Tomlinson, Teresa S. Latham, Russell E. Ware
Journal: Blood
Blood (2023) 142 (Supplement 1): 6.
https://doi.org/10.1182/blood-2023-172919
Published: 2023
Journal Articles

Hydroxyurea treatment is associated with lower malaria incidence in children with sickle cell anemia in sub-Saharan Africa

Clinical Trials & Observations
Peter Olupot-Olupot, George Tomlinson, Thomas N. Williams, Léon Tshilolo, Brígida Santos, Luke R. Smart, Kathryn McElhinney, Thad A. Howard, Banu Aygun, Susan E. Stuber, Adam Lane, Teresa S. Latham, Russell E. Ware
Journal: Blood
Blood (2023) 141 (12): 1402–1410.
https://doi.org/10.1182/blood.2022017051
Published: 2023
Includes: Supplemental data
Journal Articles

The International Hemoglobinopathy Research Network (INHERENT): An International Initiative to Study the Role of Genetic Modifiers in Hemoglobinopathies

Petros Kountouris, Coralea Stephanou, Natasha M. Archer, Fedele Bonifazi, Viviana Giannuzzi, Kevin H.M. Kuo, Aurelio Maggio, Julie Makani, Maria Del Mar Mañú Pereira, Kyriaki Michailidou, Siana Watoky Nkya, Obiageli E Nnodu, Sara Trompeter, Leon Tshilolo, Ambroise Wonkam, Bin Alwi Zilfalil, Baba PD Inusa, Marina Kleanthous
Journal: Blood
Blood (2021) 138 (Supplement 1): 948.
https://doi.org/10.1182/blood-2021-146078
Published: 2021
Journal Articles

Hydroxyurea Reduces the Transfusion Burden in Children with Sickle Cell Anemia: The Reach Experience

Alexandra Power-Hays, George A. Tomlinson, Leon Tshilolo, Brigida Santos, Thomas N. Williams, Peter Olupot-Olupot, Patrick T. McGann, Banu Aygun, Adam Lane, Susan E. Stuber, Teresa Latham, Russell E. Ware
Journal: Blood
Blood (2021) 138 (Supplement 1): 11.
https://doi.org/10.1182/blood-2021-146632
Published: 2021
Journal Articles

Novel Genetic Loci That Influence Fetal Hemoglobin Expression in Children with Sickle Cell Anemia

Anu Marahatta, PhD, Thad A. Howard, MS, Susan E. Stuber, MA, Kathryn L McElhinney, BS, Leon Tshilolo, MDPhD, Thomas N. Williams, MDPhD, Peter Olupot-Olupot, MDPhD, Brigida Santos, MD, Chandy C. John, MD MS, Robert Opoka, MMED, Rosa M. Nieves, MD, Rafael Mena, MD, Jasmine Baker, PhD, Teresa Latham, MA, Jonathan M. Flanagan, PhD, Russell E. Ware, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-143025
Published: 2020
Journal Articles

Building Capacity and Assessing Stroke Risk with Transcranial Doppler Ultrasonography in Sub-Saharan Africa: The Reach Experience

Brigida Santos, MD, Maria Nakafeero, Adam Lane, PhD, Leon Tshilolo, MDPhD, Thomas N. Williams, MDPhD, Peter Olupot-Olupot, MDPhD, Janet Adams, Banu Aygun, MD, Susan E. Stuber, MA, George A. Tomlinson, PhD BSc, MSc, Teresa Latham, MA, Patrick T. McGann, MD MS, Russell E. Ware, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17–18.
https://doi.org/10.1182/blood-2020-142318
Published: 2020
Journal Articles

Optimizing Hydroxyurea Therapy with Reduced Laboratory Monitoring for Children with Sickle Cell Anemia in Sub-Saharan Africa: The Reach Experience

Banu Aygun, MD, George A. Tomlinson, PhD BSc, MSc, Patrick T. McGann, MD MS, Leon Tshilolo, MDPhD, Thomas N. Williams, MDPhD, Peter Olupot-Olupot, MDPhD, Brigida Santos, MD, Susan E. Stuber, MA, Adam Lane, PhD, Teresa Latham, MA, Russell E. Ware, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17.
https://doi.org/10.1182/blood-2020-134180
Published: 2020
Journal Articles

Genetic Variants That Influence Fetal Hemoglobin Expression from Hydroxyurea Treatment

Anu Marahatta, PhD, Jonathan M. Flanagan, PhD, Thad A. Howard, MS, Nicole Mortier, MHS, PA-C, William Schultz, MHS, PA, Kathryn L McElhinney, BS, Leon Tshilolo, MDPhD, Thomas N. Williams, MDPhD, Peter Olupot-Olupot, MDPhD, Brigida Santos, MD, Chandy C. John, MD MS, Robert Opoka, MMED, Rosa M. Nieves, MD, Rafael Mena, MD, Marvin E Reid, MB, BS, PhD, Angela Rankine-Mullings, MBBS, Jasmine Baker, PhD, Patrick T. McGann, MD MS, Banu Aygun, MD, Adam Lane, PhD, George A. Tomlinson, PhD BSc, MSc, Teresa Latham, MA, Susan E. Stuber, MA, Russell E. Ware, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
https://doi.org/10.1182/blood-2020-143139
Published: 2020
Journal Articles

Effects of Hydroxyurea Treatment on Malaria Infections in Sub-Saharan Africa

Peter Olupot-Olupot, George A. Tomlinson, PhD BSc, MSc, Teresa S. Latham, MA, Patrick T. McGann, MD, Brigida Santos, Banu Aygun, MD, Susan Stuber, MA, Leon Tshilolo, MD PhD, Adam Lane, PhD, Thomas N. Williams, Russell E. Ware, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 522.
https://doi.org/10.1182/blood-2019-129251
Published: 2019
Journal Articles

Splenomegaly in Children with Sickle Cell Anemia Receiving Hydroxyurea in Sub-Saharan Africa

Leon Tshilolo, MD PhD, George A. Tomlinson, PhD BSc, MSc, Patrick T. McGann, MD, Teresa S. Latham, MA, Peter Olupot-Olupot, Brigida Santos, Banu Aygun, MD, Susan Stuber, MA, Adam Lane, PhD, Thomas N. Williams, Russell E. Ware, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 993.
https://doi.org/10.1182/blood-2019-129937
Published: 2019
Journal Articles

Realizing Effectiveness across Continents with Hydroxyurea (REACH): A Prospective Multi-National Trial of Hydroxyurea for Sickle Cell Anemia in Sub-Saharan Africa

Leon Tshilolo, MDPhD, George Tomlinson, Thomas N. Williams, Brigida Santos, Peter Olupot-Olupot, Adam Lane, PhD, Banu Aygun, MD, Susan Stuber, MA, Teresa Latham, MA, Patrick T. McGann, MD, Russell E. Ware, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3.
https://doi.org/10.1182/blood-2018-99-113818
Published: 2018