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Kunhua Qin
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Journal Articles

A Novel Genome-Scale CRISPR-Cas12a Screen Identifies Ptpa As a Fetal Hemoglobin Regulator Via BCL11A

Elizabeth A. Traxler, Chad Komar, Megan Saari, Quynn Hotan, A Josephine Thrasher, Eugene Khandros, Kunhua Qin, Osheiza Abdulmalik, Claire Shao, Qingzhou Chen, Andy J. Minn, Cheryl A. Keller, Junwei Shi, Gerd A. Blobel
Journal: Blood
Blood (2024) 144 (Supplement 1): 412.
https://doi.org/10.1182/blood-2024-210117
Published: 2024
Journal Articles

Genome-Scale CRISPR-Cas12a Screen Identifies Novel Fetal Hemoglobin Regulators

Elizabeth A. Traxler, Chad Komar, Megan Saari, A Josephine Thrasher, Kunhua Qin, Eugene Khandros, Quynn Hotan, Osheiza Abdulmalik, Claire Shao, Qingzhou Chen, Andy J. Minn, Cheryl A. Keller, Junwei Shi, Gerd A. Blobel
Journal: Blood
Blood (2023) 142 (Supplement 1): 1101.
https://doi.org/10.1182/blood-2023-189547
Published: 2023
Journal Articles

Molecular basis of polycomb group protein–mediated fetal hemoglobin repression

Kunhua Qin, Xianjiang Lan, Peng Huang, Megan S. Saari, Eugene Khandros, Cheryl A. Keller, Belinda Giardine, Osheiza Abdulmalik, Junwei Shi, Ross C. Hardison, Gerd A. Blobel
Journal: Blood
Blood (2023) 141 (22): 2756–2770.
https://doi.org/10.1182/blood.2022019578
Published: 2023
Includes: Supplemental data
Journal Articles

Mechanisms of Polycomb Group Protein-Mediated Fetal Hemoglobin Silencing

Kunhua Qin, Peng Huang, Xianjiang Lan, Megan S. Saari, Eugene Khandros, Osheiza Y. Abdulmalik, Cheryl A. Keller, Belinda M. Giardine, Ross C. Hardison, Junwei Shi, Gerd A. Blobel
Journal: Blood
Blood (2022) 140 (Supplement 1): 5382–5383.
https://doi.org/10.1182/blood-2022-165560
Published: 2022
Journal Articles

HIC2 Controls Developmental Hemoglobin Switching By Repressing BCL11A Transcription

Peng Huang, Scott A. Peslak, Eugene Khandros, Xianjiang Lan, Kunhua Qin, Malini Sharma, Cheryl A. Keller, Belinda Giardine, Osheiza Abdulmalik, Stella T. Chou, Junwei Shi, Ross C. Hardison, Gerd A. Blobel
Journal: Blood
Blood (2021) 138 (Supplement 1): 571.
https://doi.org/10.1182/blood-2021-146637
Published: 2021
Journal Articles

Control of Fetal Hemoglobin Levels By NFI Transcription Factors

Kunhua Qin, Peng Huang, PhD, Anran Huang, BS, Ruopeng Feng, PhD, Thiyagaraj Mayuranathan, Cheryl A. Keller, PhD, Belinda Giardine, Ross C. Hardison, PhD, Mitchell J. Weiss, MD PhD, Junwei Shi, PhD, Gerd A. Blobel, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 54.
https://doi.org/10.1182/blood-2020-136167
Published: 2020
Journal Articles

ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression

Xianjiang Lan, PhD, Ren Ren, PhD, Ruopeng Feng, PhD, Lana C Ly, Yemin Lan, PhD, Zhe Zhang, PhD, Nicholas Aboreden, Kunhua Qin, John R Horton, Jeremy D. Grevet, PhD, Thiyagaraj Mayuranathan, Osheiza Abdulmalik, DVM, Cheryl A. Keller, PhD, Belinda Giardine, Ross C. Hardison, PhD, Merlin Crossley, PhD, Mitchell J. Weiss, MD PhD, Xiaodong Cheng, PhD, Junwei Shi, PhD, Gerd A. Blobel, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 54.
https://doi.org/10.1182/blood-2020-137564
Published: 2020
Journal Articles

The HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expression

Peng Huang, Scott A. Peslak, Xianjiang Lan, Eugene Khandros, Jennifer A. Yano, Malini Sharma, Cheryl A. Keller, Belinda Giardine, Kunhua Qin, Osheiza Abdulmalik, Ross C. Hardison, Junwei Shi, Gerd A. Blobel
Journal: Blood
Blood (2020) 135 (24): 2121–2132.
https://doi.org/10.1182/blood.2020005301
Published: 2020
Includes: Supplemental data
Journal Articles

Heme-Regulated Inhibitor (HRI) Activates Transcription Factor ATF4 to Promote BCL11A Transcription and Fetal Hemoglobin Silencing

Peng Huang, PhD, Scott A. Peslak, MD PhD, Xianjiang Lan, PhD, Eugene Khandros, MD PhD, Malini Sharma, BS, Kunhua Qin, PhD, Cheryl A Keller, PhD, Belinda Giardine, Junwei Shi, PhD, Ross C. Hardison, PhD, Gerd A. Blobel, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 814.
https://doi.org/10.1182/blood-2019-123837
Published: 2019