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Klara E. Noble
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Journal Articles

SCA-AD, a Novel Method to Uniformly Identify Cells across Single-Cell RNA Sequencing Datasets, Applied to Adult and Pediatric Self-Renewing AML Cells

Yoonkyu Lee, Wen Wang, Timothy K Starr, Klara E Noble-Orcutt, Chad L Myers, Zohar Sachs
Journal: Blood
Blood (2024) 144 (Supplement 1): 2218.
https://doi.org/10.1182/blood-2024-208337
Published: 2024
Journal Articles

Single Cell Correlation Analysis: A Novel Method to Analyze Single Cell RNA Sequencing Data Identifies a Self-Renewing Subpopulation of Human Acute Myeloid Leukemia Stem Cells

Yoonkyu Lee, Wen Wang, Timothy K Starr, Klara E Noble-Orcutt, Chad L Myers, Zohar Sachs
Journal: Blood
Blood (2023) 142 (Supplement 1): 241.
https://doi.org/10.1182/blood-2023-186606
Published: 2023
Journal Articles

Forward Genetic Screen Implicates Drivers of Leukemic Progression in a Novel Model of Trp53 R270H myelodysplastic Syndrome

Daniel Chang, Klara E Noble-Orcutt, Wendy Hudson, Aishwarya Iyer, Emily Pomeroy, Craig E. Eckfeldt, Aaron Sarver, Nuri Alpay Temiz, Michael Linden, Chad L Myers, David A. Largaespada, Zohar Sachs
Journal: Blood
Blood (2023) 142 (Supplement 1): 315.
https://doi.org/10.1182/blood-2023-189336
Published: 2023
Journal Articles

TP53 Altered Acute Myeloid Leukemia Stem Cells Hyperactivate Nuclear Factor-Kappa B

Marie Lue Antony, Klara E Noble-Orcutt, Jeffrey Lee Jensen, Fiona He, Zohar Sachs
Journal: Blood
Blood (2022) 140 (Supplement 1): 3399–3400.
https://doi.org/10.1182/blood-2022-170479
Published: 2022
Journal Articles

Single-Cell Analysis Reveals Molecular Mechanisms of NRAS-Mediated Leukemia Stem Cell Self-Renewal in a Murine Model of AML

Rebecca S. Larue, PhD, Klara E Noble, B.S., Conner Hansen, B.S., Ngoc Ha, B.S., David A Largaespada, PhD, Zohar Sachs, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3060.
https://doi.org/10.1182/blood.V126.23.3060.3060
Published: 2015
Journal Articles

NRAS G12V oncogene facilitates self-renewal in a murine model of acute myelogenous leukemia

Zohar Sachs, Rebecca S. LaRue, Hanh T. Nguyen, Karen Sachs, Klara E. Noble, Nurul Azyan Mohd Hassan, Ernesto Diaz-Flores, Susan K. Rathe, Aaron L. Sarver, Sean C. Bendall, Ngoc A. Ha, Miechaleen D. Diers, Garry P. Nolan, Kevin M. Shannon, David A. Largaespada
Journal: Blood
Blood (2014) 124 (22): 3274–3283.
https://doi.org/10.1182/blood-2013-08-521708
Published: 2014
Includes: Supplemental data