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Journal Articles

Immune Exhaustion and 2B4 Expression in Human T-Cell Lymphotropic Virus Type 1(HTLV-1) Infection

Ezinne Chioma Chibueze, MD, Yohann White, MD, PhD, Makoto Yoshimitsu, MD PhD, Tomohiro Kozako, PhD, Shinsuke Suzuki, MD, PhD, Kakushi Matsushita, MD, Kimiharu Uozumi, MD, PhD, Naomichi Arima, MD, PhD

Blood (2012) 120 (21): 4807.

https://doi.org/10.1182/blood.V120.21.4807.4807

Published: 2012

Journal Articles

Characterization of Long-Term Survivors and a Predictive Model for Aggressive Adult T-Cell Leukemia-Lymphoma (ATL): An Ancillary Study by the Japan Clinical Oncology Group, JCOG0902A

Blood (2011) 118 (21): 881.

https://doi.org/10.1182/blood.V118.21.881.881

Published: 2011

Journal Articles

CD70 Expression on HTLV-1 Infected T Cells of Carriers and ATL Patients and Its Clinical Significance

Izumi Masamoto, BSc, MSc, Sawako Horai, PhD, Tomohiro Kozako, PhD, Makoto Yoshimitsu, MD, Junko Niimoto, BSc, Yohann White, BMedSc, MBBS, Kimiharu Uozumi, MD, PhD, Shinsuke Suzuki, MD, PhD, Naomichi Arima, MD, PhD

Blood (2010) 116 (21): 1730.

https://doi.org/10.1182/blood.V116.21.1730.1730

Published: 2010

Journal Articles

Human T-cell leukemia virus type I (HTLV-1) proviral load and disease progression in asymptomatic HTLV-1 carriers: a nationwide prospective study in Japan

Blood (2010) 116 (8): 1211–1219.

https://doi.org/10.1182/blood-2009-12-257410

Published: 2010

Includes: Supplemental data

Journal Articles

Target Epitopes of Human T Lymphotropic Virus 1 Recognized by Class I MHC-Restricted Cytotoxic T Lymphocytes in HAM/TSP Patients and Infected Patients with Autoimmune Disorders.

Tomohiro Kozako, PhD, Masaki Akimoto, MD, PhD, Yohann White, MD, Shingo Toji, Kakushi Matsushita, MD, PhD, Ryuji Kubota, MD, PhD, Shuji Izumo, MD, PhD, Shinsuke Suzuki, MD, PhD, Kimiharu Uozumi, MD, Hiroshi Shimeno, PhD, Shinji Soeda, PhD, Naomichi Arima, MD, PhD

Blood (2009) 114 (22): 2660.

https://doi.org/10.1182/blood.V114.22.2660.2660

Published: 2009

Journal Articles

Increased Frequency of HTLV-1 Tax Specific CD8+ Regulatory T-Cells in HTLV-1 Infected Individuals.

Yohann White, MBBS, BMedSc, Makoto Yoshimitsu, MD, Tomohiro Kozako, PhD, Kakushi Matsushita, MD, PhD, Kimiharu Uozumi, MD, Shinsuke Suzuki, MD, PhD, Hiroki Kofune, BSc, Naomichi Arima, MD, PhD

Blood (2009) 114 (22): 3676.

https://doi.org/10.1182/blood.V114.22.3676.3676

Published: 2009

Journal Articles

Phase I Study of KW-0761, a Defucosylated Anti-CCR4 Antibody, in Relapsed Patients (Pts) with Adult T-Cell Leukemia-Lymphoma (ATL) or Peripheral T-Cell Lymphoma (PTCL): Updated Results.

Kazuhito Yamamoto, MD, PhD, Kensei Tobinai, MD, PhD, Atae Utsunomiya, MD, Kunihiro Tsukasaki, MD, PhD, Naokuni Uike, MD, PhD, Kimiharu Uozumi, MD, Masao Tomonaga, MD, Koji Matsushima, MD, PhD, Kenya Shitara, PhD, Shiro Akinaga, PhD, Ryuzo Ueda, MD, PhD

Blood (2008) 112 (11): 1007.

https://doi.org/10.1182/blood.V112.11.1007.1007

Published: 2008

Journal Articles

CTL Exhaustion in Persistent HTLV-1 Infection and ATLL Is Restored through PD-1/PD-L1 Pathway.

Tomohiro Kozako, PhD, Makoto Yoshimitsu, MD, Hiroshi Fujiwara, MD, PhD, Izumi Masamoto, MS, Sawako Horai, PhD, Masaki Akimoto, MD, PhD, Yukio Suruga, MD, PhD, Hideaki Kawada, MD, Heiichiro Hamada, MD, Noriko Aoki, MD, Shinsuke Suzuki, MD, PhD, Kakushi Matsushita, MD, PhD, Kimiharu Uozumi, MD, PhD, Chuwa Tei, MD, PhD, Naomichi Arima, MD, PhD

Blood (2007) 110 (11): 511.

https://doi.org/10.1182/blood.V110.11.511.511

Published: 2007

Journal Articles

Phase I Study of KW-0761, a Humanized Anti-CCR4 Antibody, in Patients (Pts) with Relapsed or Refractory Adult T-Cell Leukemia-Lymphoma (ATLL) and Peripheral T-Cell Lymphoma (PTCL): Preliminary Results.

Naokuni Uike, MD, Kunihiro Tsukasaki, MD, Atae Utsunomiya, MD, Kensei Tobinai, MD, Yasuo Morishima, MD, Kimiharu Uozumi, MD, Masao Tomonaga, MD, Koji Matsushima, MD, Knya Shitara, Ph.D., Shiro Akinaga, Ph.D., Ryuzo Ueda, MD

Blood (2007) 110 (11): 4492.

https://doi.org/10.1182/blood.V110.11.4492.4492

Published: 2007

Journal Articles

The Frequency, Diversity, and Function of Human T-Cell Leukemia Virus Type 1-Specific CD8+ T-Cell Is Reduced in Adult T-Cell Leukemia Patients.

Tomohiro Kozako, PhD, Masaki Akimoto, MD, Izumi Masamoto, Makoto Yoshimitsu, MD, Kakushi Matsushita, MD, PhD, Shinsuke Suzuki, MD, PhD, Kimiharu Uozumi, MD, PhD, Naomichi Arima, MD, PhD

Blood (2006) 108 (11): 1264.

https://doi.org/10.1182/blood.V108.11.1264.1264

Published: 2006

Journal Articles

Characterization of T-Cell Lymphoma Cell Lines with a Novel t(9;14)(q34;q11.2) Rearrangement: Does gamma-Secretase Inhibitor Sensitivity Depend on Intragenic NOTCH1 Breakpoint?.

Shinsuke Suzuki, MD, PhD, Stefan Nagel, PhD, Bjoern Schneider, Maren Kaufmann, Dorothea Anders, Hirohito Tsubouchi, MD, Kimiharu Uozumi, MD, Naomichi Arima, MD, Hans G. Drexler, MD, Roderick A.F. MacLeod, PhD

Blood (2006) 108 (11): 2332.

https://doi.org/10.1182/blood.V108.11.2332.2332

Published: 2006

Journal Articles

Efficient intervention of growth and infiltration of primary adult T-cell leukemia cells by an HIV protease inhibitor, ritonavir

M. Zahidunnabi Dewan, Jun-nosuke Uchihara, Kazuo Terashima, Mitsuo Honda, Tetsutaro Sata, Mamoru Ito, Nobutaka Fujii, Kimiharu Uozumi, Kunihiro Tsukasaki, Masao Tomonaga, Yoko Kubuki, Akihiko Okayama, Masakazu Toi, Naoki Mori, Naoki Yamamoto

Blood (2006) 107 (2): 716–724.

https://doi.org/10.1182/blood-2005-02-0735

Published: 2006

Journal Articles

Dual targeting of transformed and untransformed HTLV-1–infected T cells by DHMEQ, a potent and selective inhibitor of NF-κB, as a strategy for chemoprevention and therapy of adult T-cell leukemia

Mariko Watanabe, Takeo Ohsugi, Momoko Shoda, Takaomi Ishida, Shigemi Aizawa, Masae Maruyama-Nagai, Atae Utsunomiya, Shin Koga, Yasuaki Yamada, Shimeru Kamihira, Akihiko Okayama, Hiroshi Kikuchi, Kimiharu Uozumi, Kazunari Yamaguchi, Masaaki Higashihara, Kazuo Umezawa, Toshiki Watanabe, Ryouichi Horie

Blood (2005) 106 (7): 2462–2471.

https://doi.org/10.1182/blood-2004-09-3646

Published: 2005

Includes: Supplemental data

Journal Articles

Expression of functional lung resistance–related protein predicts poor outcome in adult T-cell leukemia

Nobuhito Ohno, Ayako Tani, Kimiharu Uozumi, Shuichi Hanada, Tatsuhiko Furukawa, Suminori Akiba, Tomoyuki Sumizawa, Atae Utsunomiya, Terukatsu Arima, Shin-ichi Akiyama

Blood (2001) 98 (4): 1160–1165.

https://doi.org/10.1182/blood.V98.4.1160

Published: 2001

NARROW

Immune Exhaustion and 2B4 Expression in Human T-Cell Lymphotropic Virus Type 1(HTLV-1) Infection

Characterization of Long-Term Survivors and a Predictive Model for Aggressive Adult T-Cell Leukemia-Lymphoma (ATL): An Ancillary Study by the Japan Clinical Oncology Group, JCOG0902A

CD70 Expression on HTLV-1 Infected T Cells of Carriers and ATL Patients and Its Clinical Significance

Human T-cell leukemia virus type I (HTLV-1) proviral load and disease progression in asymptomatic HTLV-1 carriers: a nationwide prospective study in Japan

Target Epitopes of Human T Lymphotropic Virus 1 Recognized by Class I MHC-Restricted Cytotoxic T Lymphocytes in HAM/TSP Patients and Infected Patients with Autoimmune Disorders.

Increased Frequency of HTLV-1 Tax Specific CD8+ Regulatory T-Cells in HTLV-1 Infected Individuals.

Phase I Study of KW-0761, a Defucosylated Anti-CCR4 Antibody, in Relapsed Patients (Pts) with Adult T-Cell Leukemia-Lymphoma (ATL) or Peripheral T-Cell Lymphoma (PTCL): Updated Results.

CTL Exhaustion in Persistent HTLV-1 Infection and ATLL Is Restored through PD-1/PD-L1 Pathway.

Phase I Study of KW-0761, a Humanized Anti-CCR4 Antibody, in Patients (Pts) with Relapsed or Refractory Adult T-Cell Leukemia-Lymphoma (ATLL) and Peripheral T-Cell Lymphoma (PTCL): Preliminary Results.

The Frequency, Diversity, and Function of Human T-Cell Leukemia Virus Type 1-Specific CD8+ T-Cell Is Reduced in Adult T-Cell Leukemia Patients.

Characterization of T-Cell Lymphoma Cell Lines with a Novel t(9;14)(q34;q11.2) Rearrangement: Does gamma-Secretase Inhibitor Sensitivity Depend on Intragenic NOTCH1 Breakpoint?.

Efficient intervention of growth and infiltration of primary adult T-cell leukemia cells by an HIV protease inhibitor, ritonavir

Dual targeting of transformed and untransformed HTLV-1–infected T cells by DHMEQ, a potent and selective inhibitor of NF-κB, as a strategy for chemoprevention and therapy of adult T-cell leukemia

Expression of functional lung resistance–related protein predicts poor outcome in adult T-cell leukemia

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American Society of Hematology

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American Society of Hematology

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