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Jozef Madzo
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Journal Articles

Reprogramming T Cell EZH2 to Counteract CAR T Cell Dysfunction during Tumor Control

Mimi Chen, Wenbin Mo, Gennaro Clando, Yuanyuan Tian, Ciril Abraham, Qingrong Huang, Ying WANG, Morgan Chaunzwa, Yan Zhou, Andrew Ip, Andre Goy, Jaroslav Jelinek, Jozef Madzo, Jean-Pierre Issa, Yi Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 2039.
https://doi.org/10.1182/blood-2024-207438
Published: 2024
Journal Articles

Inhibiting Tumor Cell CDK9 Reprograms Cell Death Pathways to Enhance Efficacy of CAR T Cell Therapy

Ciril Abraham, Wenbin Mo, Tien Bui, Mimi Chen, Yuanyuan Tian, Gennaro Clando, Morgan Chaunzwa, Ying WANG, Jozef Madzo, Jean-Pierre Issa, Yi Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 3430.
https://doi.org/10.1182/blood-2024-211530
Published: 2024
Journal Articles

Tissue-infiltrating alloreactive T cells require Id3 to deflect PD-1–mediated immune suppression during GVHD

Ying Wang, Shan He, Gennaro Calendo, Tien Bui, Yuanyuan Tian, Che Young Lee, Yan Zhou, Xin Zhao, Ciril Abraham, Wenbin Mo, Mimi Chen, Ruqayyah Sanders-Braggs, Jozef Madzo, Jean-Pierre Issa, Elizabeth O. Hexner, David L. Wiest, Ran Reshef, Hai-Hui Xue, Yi Zhang
Journal: Blood
Blood (2024) 143 (2): 166–177.
https://doi.org/10.1182/blood.2023021126
Published: 2024
Includes: Supplemental data
Journal Articles

The Phosphorylation State of Ezh2 Determines Its Capacity to Maintain CD8 + Memory T Cells for Antitumor Immunity

Shan He, PhD, Yongnian Liu, Lijun Meng, Hongxing SUN, Ying Wang, Yun Ji, Janaki Purushe, BS, Pan Chen, Changhong Li, Jozef Madzo, Jean-Pierre Issa, MD, Jonathan Soboloff, Ran Reshef, MD, Bethany Moore, Luca Gattinoni, Yi Zhang, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4455.
https://doi.org/10.1182/blood.V130.Suppl_1.4455.4455
Published: 2017
Journal Articles

DNA Hydroxymethylation Profiling Reveals That WT1 Mutations Result in Loss of TET2 Function in Acute Myeloid Leukemia

Raajit K. Rampal, MD PhD, Altuna Alkalin, Jozef Madzo, PhD, Aparna Vasanthakumar, BSc, MSc, PhD, Elodie Pronier, PhD, Jay P. Patel, Yushan Li, Jihae Ahn, BS, Omar Abdel-Wahab, MD, Alan H. Shih, MDPhD, Chao Lu, Patrick Ward, Jennifer J Tsai, MD, Todd Hricik, Jacob Tallman, Valeria Tosello, PhD, Xinyang Zhao, PhD, Danette Daniels, Qing Dai, Luisa Ciminio, Iannis Aifantis, PhD, Chuan He, PhD, François Fuks, Martin S. Tallman, MD, Adolfo A. Ferrando, MD PhD, Stephen Nimer, MD, Elisabeth Paietta, PhD, Craig B. Thompson, MD, Jonathan D. Licht, MD, Christopher E Mason, PhD, Lucy A Godley, MD PhD, Ari M Melnick, MD, Maria E Figueroa, MD, Ross L Levine, MD
Journal: Blood
Blood (2014) 124 (21): 365.
https://doi.org/10.1182/blood.V124.21.365.365
Published: 2014
Journal Articles

Identifying familial myelodysplastic/acute leukemia predisposition syndromes through hematopoietic stem cell transplantation donors with thrombocytopenia

Jane E. Churpek, Eric Nickels, Rafael Marquez, Katarzyna Rojek, Bohao Liu, Rachelle Lorenz, Janet Lepore, Jozef Madzo, Amittha Wickrema, Andrew S. Artz, Koen van Besien, Lucy A. Godley
Journal: Blood
Blood (2012) 120 (26): 5247–5249.
https://doi.org/10.1182/blood-2012-09-457945
Published: 2012
Includes: Supplemental data
Journal Articles

ETV6/RUNX1 ( TEL/AML1 ) is a frequent prenatal first hit in childhood leukemia

Jan Zuna, Jozef Madzo, Ondrej Krejci, Zuzana Zemanova, Marketa Kalinova, Katerina Muzikova, Michal Zapotocky, Julia Starkova, Ondrej Hrusak, Jiri Horak, Jan Trka
Journal: Blood
Blood (2011) 117 (1): 368–369.
https://doi.org/10.1182/blood-2010-09-309070
Published: 2011
Journal Articles

Silencing of TEL/AML1 In Definitive Leukemic Cells Does Not Impair Cell Survival

Marketa Zaliova, MD, Jozef Madzo, PhD, Gunnar Cario, MD, Jan Trka, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3229.
https://doi.org/10.1182/blood.V116.21.3229.3229
Published: 2010
Journal Articles

Pre-Donor Evaluation of an HLA Matched Sibling Identifies a Novel Inherited RUNX1 Mutation Encoding a Missense Mutation Found Outside of the RUNT Domain in Familial Platelet Disorder

Jacqueline S Garcia, MD, Jozef Madzo, PhD, Devin Cooper, Sarah A Jackson, MS, Kenan Onel, MD, PhD, Richard A. Larson, MD, Andrew Artz, MD, MS, Lucy A Godley, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2709.
https://doi.org/10.1182/blood.V116.21.2709.2709
Published: 2010
Journal Articles

Molecular Characterization of a Novel 3' Mutation in RUNX1 in a New Pedigree with Familial Platelet Disorder.

Jane E Churpek, Jacqueline S Garcia, Jozef Madzo, Sarah Jackson, Kenan Onel, Lucy A Godley
Journal: Blood
Blood (2009) 114 (22): 1626.
https://doi.org/10.1182/blood.V114.22.1626.1626
Published: 2009
Journal Articles

ETV6/RUNX1 Dysregulates Genes with RUNX1 Binding Site Via Mechanism Reversible by Histone Deacetylase Inhibitors.

Julia Starkova, Jozef Madzo, Gunnar Cario, Marketa Zaliova, Anthony Ford, Jan Trka
Journal: Blood
Blood (2006) 108 (11): 2226.
https://doi.org/10.1182/blood.V108.11.2226.2226
Published: 2006
Journal Articles

Identification of Genes Differentially Expressed after HDACi Treatment in TEL/AML1-Positive Leukaemic Cells.

Julia Starkova, Jozef Madzo, Gunnar Cario, Katerina Krejcikova, Ondrej Hrusak, Jan Trka
Journal: Blood
Blood (2005) 106 (11): 4364.
https://doi.org/10.1182/blood.V106.11.4364.4364
Published: 2005
Journal Articles

In-Utero Origin of Childhood Acute Leukaemias.

Tatiana Burjanivova, Jozef Madzo, Katerina Muzikova, Claus Meyer, Björn Schneider, Jan Stary, Rolf Marschalek, Jan Trka, Jan Zuna
Journal: Blood
Blood (2005) 106 (11): 1445.
https://doi.org/10.1182/blood.V106.11.1445.1445
Published: 2005
Journal Articles

Histone Deacetylase Inhibitors Are Capable to Modify Leukaemia-Specific Phenotype of TEL/AML1-Positive Leukaemic Cells.

Julia Starkova, MSc, Jozef Madzo, PhD, Tomas Kalina, MD, Martina Vaskova, MSc, Jan Trka, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 1891.
https://doi.org/10.1182/blood.V104.11.1891.1891
Published: 2004