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Journal Articles

Inflammation Mediated By TNFα Disrupts the Autophagic Flux and Oxidative Phosphorylation of Megakaryocytes and Platelets through the Downregulation of STX17

Guadalupe Rojas-Sanchez, Jorge Calzada-Martinez, Brandon McMahon, Orlando Esparza, Giovanny Hernandez, Dennis L Le, Eric Wartchow, Tzu Phang, Travis Nemkov, Angelo D'Alessandro, Paola Maycotte, Andrew Thorburn, Jose A. Lopez, Pavel Davizon-Castillo

Blood (2023) 142 (Supplement 1): 2567.

https://doi.org/10.1182/blood-2023-185498

Published: 2023

Journal Articles

Steady-State Von Willebrand Factor Antigen Levels Predict Low Platelet Counts and Risk for Complications in Hospitalizations for Painful Sickle Cell Vaso-Occlusive Episodes

Xu Zhang, Binal Shah, Jin Han, Jose A. Lopez, Dominic W. Chung, Junmei Chen, Victor R. Gordeuk, Santosh L. Saraf

Blood (2023) 142 (Supplement 1): 2483.

https://doi.org/10.1182/blood-2023-190297

Published: 2023

Journal Articles

TRPM8 Contributes to Early Temperature-Induced Platelet Activation

Anastasiia Stratiievska, Olga Filippova, Hasan Tahsin Ozpolat, Daire Byrne, S. Lawrence Bailey, Molly Mollica, Jeffrey Harris, Kali Esancy, Ajay Daka, Nathan Sniadecki, Jose A. Lopez, Moritz Stolla

Blood (2023) 142 (Supplement 1): 5566.

https://doi.org/10.1182/blood-2023-174122

Published: 2023

Journal Articles

High-Density Lipoprotein Inhibits Microvascular and Arterial Thrombosis in Mice By Attenuating VWF Self-Association

Raymond Adili, Nicole Rhoads, Jeffrey Harris, Minhua Ling, Junmei Chen, Jose A. Lopez, Dominic W. Chung

Blood (2023) 142 (Supplement 1): 3936.

https://doi.org/10.1182/blood-2023-178884

Published: 2023

Journal Articles

Self-Association of Von Willebrand Factor (VWF) into Prothrombotic Fibers Is Most Potently Enhanced By the Highly Atherogenic Small, Dense Fraction of Low-Density Lipoprotein (sd-LDL)

Junmei Chen, Forrest Nussdorfer, Raymond Adili, Kimsey Platten, Nicole Rhoads, Richard Maldonado, Franklin Reed, Yi Wang, Minhua Ling, Sergio Fazio, Xiaoyun Fu, Nathalie Pamir, Jose A. Lopez, Dominic W. Chung

Blood (2023) 142 (Supplement 1): 504.

https://doi.org/10.1182/blood-2023-188325

Published: 2023

Journal Articles

The Actin Bundling Protein L-Plastin Mediates Platelet Force Generation and Thrombosis

Seema Bhatlekar, Shancy Jacob, Marina Tistao, Molly Y Mollica, Nicole Rhoads, Lili Chen, Bhanu Kanth Manne, Darian Murray, Siqi Guo, Sharon Celeste Morley, Jesse W Rowley, Matthew T. Rondina, Raymond Adili, Jose A. Lopez, Li Guo

Blood (2023) 142 (Supplement 1): 2560.

https://doi.org/10.1182/blood-2023-178052

Published: 2023

Journal Articles

Low-density lipoprotein promotes microvascular thrombosis by enhancing von Willebrand factor self-association

Dominic W. Chung, Kimsey Platten, Koya Ozawa, Reheman Adili, Nathalie Pamir, Forrest Nussdorfer, Alexander St. John, Minhua Ling, Jennie Le, Jeff Harris, Nicole Rhoads, Yi Wang, Xiaoyun Fu, Junmei Chen, Sergio Fazio, Jonathan R. Lindner, José A. López

Blood (2023) 142 (13): 1156–1166.

https://doi.org/10.1182/blood.2023019749

Published: 2023

Includes: Multimedia, Supplemental data

Journal Articles

Unfolded Von Willebrand Factor Interacts with Protein S and Limits Its Anticoagulant Activity

Martha MS Sim, Hammodah Alfar, Melissa Hollifield, Dominic W. Chung, Xiaoyun Fu, Meenakshi Banerjee, Chi Peng, Xian Li, Alice Thornton, James Z Porterfield, Jamie Sturgill, Gail A Sievert, Marietta Barton-Baxter, Kenneth S Campbell, Jerold G Woodward, José A. López, Sidney W Whiteheart, Beth A Garvy, Jeremy P Wood

Blood (2022) 140 (Supplement 1): 2710–2711.

https://doi.org/10.1182/blood-2022-162612

Published: 2022

Journal Articles

Elevated Levels of Low Density Lipoprotein (LDL) Trigger VWF Self-Association into Fibers and Bundles and Potentiate Microvascular Thrombosis

Dominic W. Chung, Kimsey Platten, Koya Ozawa, Raymond Adili, Nathalie Pamir, Forrest D Nussdorfer, Alexander E St. John, Minhua Ling, Jennie Le, Jeff Harris, Junmei Chen, Sergio Fazio, Jonathan Lindner, José A. López

Blood (2022) 140 (Supplement 1): 1660–1661.

https://doi.org/10.1182/blood-2022-170092

Published: 2022

Journal Articles

Dysregulated Autophagy in Platelets from JAK2 V617F -Positive Polycythemia Vera and Essential Thrombocythemia Underlies Bioenergetic Failure As a Possible Mechanism for Thrombohemorrhagic Complications

Guadalupe Rojas Sanchez, Orlando Esparza, Brandon McMahon, Giovanny Hernandez, Dennis Le, Travis Nemkov, Angelo D'Alessandro, Andrew Thorburn, José A. López, Pavel Davizon-Castillo

Blood (2022) 140 (Supplement 1): 9590–9591.

https://doi.org/10.1182/blood-2022-170014

Published: 2022

Journal Articles

Deletion of platelet CLEC-2 decreases GPIbα-mediated integrin αIIbβ3 activation and decreases thrombosis in TTP

Bojing Shao, Christopher Hoover, Huiping Shi, Yuji Kondo, Robert H. Lee, Junmei Chen, Xindi Shan, Jianhua Song, J. Michael McDaniel, Meixiang Zhou, Samuel McGee, Karen Vanhoorelbeke, Wolfgang Bergmeier, José A. López, James N. George, Lijun Xia

Blood (2022) 139 (16): 2523–2533.

https://doi.org/10.1182/blood.2021012896

Published: 2022

Includes: Supplemental data

Journal Articles

Introduction to a review series on platelets and cancer

José A. López

Blood (2021) 137 (23): 3151–3152.

https://doi.org/10.1182/blood.2020010237

Published: 2021

Journal Articles

Plasma Proteomic Profile Associated with Platelet Dysfunction after Trauma

Alexander E St. John, MD, Yi Wang, PhD, Junmei Chen, PhD, Warren Osborn, Xu Wang, MD, Esther Lim, BS, Dominic W. Chung, PhD, Susan Stern, MD, Nathan White, MD, Xiaoyun Fu, PhD, Jose A. Lopez, MDBS

Blood (2020) 136 (Supplement 1): 9–10.

https://doi.org/10.1182/blood-2020-141361

Published: 2020

Journal Articles

Targeted Proteomics Reveals That the Dominant Mechanism of Gpibα Loss during Platelet Storage Depends on Temperature of Storage

Moritz Stolla, MD, Yi Wang, PhD, Jeffrey Miles, Barbara Osborne, RN, Yu Shen, Lydia Fang, M.S., Shawn Lawrence Bailey, BS, Warren Osborn, Junmei Chen, PhD, Jose A. Lopez, MDBS, Xiaoyun Fu, PhD

Blood (2020) 136 (Supplement 1): 31–32.

https://doi.org/10.1182/blood-2020-143077

Published: 2020

Journal Articles

Human Platelets Stored at Room Temperature Demonstrate Diminished Resistance to Oxidative Stress Compared to Those Stored at 4°C

Xiaoyun Fu, PhD, Warren Osborn, Yu Shen, Yi Wang, PhD, Jeffrey Miles, Lydia Fang, M.S., Barbara Osborne, RN, Junmei Chen, PhD, José A. López, MDBS, Moritz Stolla, MD

Blood (2020) 136 (Supplement 1): 24.

https://doi.org/10.1182/blood-2020-143190

Published: 2020

Journal Articles

Recognition of PF4-VWF complexes by heparin-induced thrombocytopenia antibodies contributes to thrombus propagation

Ian Johnston, Amrita Sarkar, Vincent Hayes, Gavin T. Koma, Gowthami M. Arepally, Junmei Chen, Dominic W. Chung, José A. López, Douglas B. Cines, Lubica Rauova, Mortimer Poncz

Blood (2020) 135 (15): 1270–1280.

https://doi.org/10.1182/blood.2018881607

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

Avadomide monotherapy in relapsed/refractory DLBCL: safety, efficacy, and a predictive gene classifier

Blood (2020) 135 (13): 996–1007.

https://doi.org/10.1182/blood.2019002395

Published: 2020

Includes: Supplemental data

Journal Articles

Thrombotic microangiopathy as a cause of cardiovascular toxicity from the BCR-ABL1 tyrosine kinase inhibitor ponatinib

Yllka Latifi, Federico Moccetti, Melinda Wu, Aris Xie, William Packwood, Yue Qi, Koya Ozawa, Weihui Shentu, Eran Brown, Toshiaki Shirai, Owen J. McCarty, Zaverio Ruggeri, Javid Moslehi, Junmei Chen, Brian J. Druker, Jose A. López, Jonathan R. Lindner

Blood (2019) 133 (14): 1597–1606.

https://doi.org/10.1182/blood-2018-10-881557

Published: 2019

Includes: Multimedia, Supplemental data

Journal Articles

Effect of Intravenous and Oral N-Acetylcysteine Treatment in a Patient with Sickle Cell Disease at Disease Baseline

Hasan Tahsin Ozpolat, MD, Junmei Chen, PhD, Xiaoyun Fu, PhD, Warren Osborn, Jennie Le, BS, Minhua Ling, PhD, Sophie Schmitter, BS, Sarah Ruuska, MPH, Dominic W. Chung, PhD, Barbara A Konkle, José A. López, MD

Blood (2018) 132 (Supplement 1): 4911.

https://doi.org/10.1182/blood-2018-99-117087

Published: 2018

Journal Articles

Introduction to a review series on nontraditional roles for the hemostatic system in the vessel wall

José A. López

Blood (2018) 132 (2): 113–114.

https://doi.org/10.1182/blood-2018-06-846097

Published: 2018

NARROW

Inflammation Mediated By TNFα Disrupts the Autophagic Flux and Oxidative Phosphorylation of Megakaryocytes and Platelets through the Downregulation of STX17

Steady-State Von Willebrand Factor Antigen Levels Predict Low Platelet Counts and Risk for Complications in Hospitalizations for Painful Sickle Cell Vaso-Occlusive Episodes

TRPM8 Contributes to Early Temperature-Induced Platelet Activation

High-Density Lipoprotein Inhibits Microvascular and Arterial Thrombosis in Mice By Attenuating VWF Self-Association

Self-Association of Von Willebrand Factor (VWF) into Prothrombotic Fibers Is Most Potently Enhanced By the Highly Atherogenic Small, Dense Fraction of Low-Density Lipoprotein (sd-LDL)

The Actin Bundling Protein L-Plastin Mediates Platelet Force Generation and Thrombosis

Low-density lipoprotein promotes microvascular thrombosis by enhancing von Willebrand factor self-association

Unfolded Von Willebrand Factor Interacts with Protein S and Limits Its Anticoagulant Activity

Elevated Levels of Low Density Lipoprotein (LDL) Trigger VWF Self-Association into Fibers and Bundles and Potentiate Microvascular Thrombosis

Dysregulated Autophagy in Platelets from JAK2 V617F -Positive Polycythemia Vera and Essential Thrombocythemia Underlies Bioenergetic Failure As a Possible Mechanism for Thrombohemorrhagic Complications

Deletion of platelet CLEC-2 decreases GPIbα-mediated integrin αIIbβ3 activation and decreases thrombosis in TTP

Introduction to a review series on platelets and cancer

Plasma Proteomic Profile Associated with Platelet Dysfunction after Trauma

Targeted Proteomics Reveals That the Dominant Mechanism of Gpibα Loss during Platelet Storage Depends on Temperature of Storage

Human Platelets Stored at Room Temperature Demonstrate Diminished Resistance to Oxidative Stress Compared to Those Stored at 4°C

Recognition of PF4-VWF complexes by heparin-induced thrombocytopenia antibodies contributes to thrombus propagation

Avadomide monotherapy in relapsed/refractory DLBCL: safety, efficacy, and a predictive gene classifier

Thrombotic microangiopathy as a cause of cardiovascular toxicity from the BCR-ABL1 tyrosine kinase inhibitor ponatinib

Effect of Intravenous and Oral N-Acetylcysteine Treatment in a Patient with Sickle Cell Disease at Disease Baseline

Introduction to a review series on nontraditional roles for the hemostatic system in the vessel wall

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American Society of Hematology

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ASH Publications

American Society of Hematology

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