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Jiri Kovarik
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Journal Articles

Neutralization of IL-1β and P-Selectin Inhibition Attenuate Organ Injury in Mice with Sickle Cell Disease

Erica M.F. Gotardo, Lucas F.S. Gushiken, Pamela L Brito, Flavia C. Leonardo, Lidiane S. Torres, Sergei Agoulnik, Jiri Kovarik, Andreas Bruederle, John Millholland, Fernando Ferreira Costa, Nicola Conran
Journal: Blood
Blood (2023) 142 (Supplement 1): 2487.
https://doi.org/10.1182/blood-2023-181895
Published: 2023
Journal Articles

P-Selectin Blockage Potentiates the Inhibiting Effects of Inflammasome Cytokine Neutralization on Leukocyte Recruitment in an In Vivo Model of Acute Sickle Cell Vaso-Occlusion

Erica M.F. Gotardo, Lidiane S. Torres, Lucas F.S. Gushiken, Pamela L. Brito, Flavia C. Leonardo, Sergei Agoulnik, Jiri Kovarik, Andreas Bruederle, John Millholland, Alessandra Vitaliti, Irmgard Förster, Fernando Ferreira Costa, Nicola Conran
Journal: Blood
Blood (2022) 140 (Supplement 1): 8230–8232.
https://doi.org/10.1182/blood-2022-159020
Published: 2022
Journal Articles

Neutralization of Inflammasome-Processed Cytokines Reduces Inflammatory Mechanisms and Leukocyte Recruitment in the Vasculature of TNF-α-Stimulated Sickle Cell Disease Mice

Lidiane S. Torres, Erica M.F. Gotardo, Flávia Costa Leonardo, Pamela L. Brito, Irmgard Förster, Jiri Kovarik, Fernando Ferreira Costa, Nicola Conran
Journal: Blood
Blood (2021) 138 (Supplement 1): 856.
https://doi.org/10.1182/blood-2021-147436
Published: 2021
Journal Articles

Therapeutic activity of multiple common γ-chain cytokine inhibition in acute and chronic GVHD

Anne-Kathrin Hechinger, Benjamin A. H. Smith, Ryan Flynn, Kathrin Hanke, Cameron McDonald-Hyman, Patricia A. Taylor, Dietmar Pfeifer, Björn Hackanson, Franziska Leonhardt, Gabriele Prinz, Heide Dierbach, Annette Schmitt-Graeff, Jiri Kovarik, Bruce R. Blazar, Robert Zeiser
Journal: Blood
Blood (2015) 125 (3): 570–580.
https://doi.org/10.1182/blood-2014-06-581793
Published: 2015
Includes: Supplemental data
Journal Articles

Common Gamma Chain Cytokines Contribute To Acute GvHD Via Perforin/Granzyme B-Mediated Cytotoxicity Of CD8 T Cells

Vincent Schwarze, Anne-Kathrin Hechinger, Ph.D., Franziska Leonhardt, Ph.D., Gabriele Prinz, Annette Schmitt-Gräff, M.D., Jiri Kovarik, Ph.D., Robert Zeiser
Journal: Blood
Blood (2013) 122 (21): 2015.
https://doi.org/10.1182/blood.V122.21.2015.2015
Published: 2013