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Cotreatment with panobinostat and JAK2 inhibitor TG101209 attenuates JAK2V617F levels and signaling and exerts synergistic cytotoxic effects against human myeloproliferative neoplastic cells

Yongchao Wang, Warren Fiskus, Daniel G. Chong, Kathleen M. Buckley, Kavita Natarajan, Rekha Rao, Atul Joshi, Ramesh Balusu, Sanjay Koul, Jianguang Chen, Andrew Savoie, Celalettin Ustun, Anand P. Jillella, Peter Atadja, Ross L. Levine, Kapil N. Bhalla
Journal: Blood
Blood (2009) 114 (24): 5024–5033.
https://doi.org/10.1182/blood-2009-05-222133
Published: 2009
Includes: Supplemental data
Journal Articles

Down-Regulation of Microrna 223 and 148a Mediates Resistance of Human Acute Myeloid Leukemia Cells to Pan-Histone Deacetylase (HDAC) Inhibitors.

Jianguang Chen, Veena Kandaswamy, Warren Fiskus, Yongchao Wang, Rekha Rao, Ramesh Balusu, Kathleen M. Buckley, Peter Atajada, Kapil N. Bhalla
Journal: Blood
Blood (2009) 114 (22): 2401.
https://doi.org/10.1182/blood.V114.22.2401.2401
Published: 2009
Journal Articles

Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells

Warren Fiskus, Yongchao Wang, Arun Sreekumar, Kathleen M. Buckley, Huidong Shi, Anand Jillella, Celalettin Ustun, Rekha Rao, Pravina Fernandez, Jianguang Chen, Ramesh Balusu, Sanjay Koul, Peter Atadja, Victor E. Marquez, Kapil N. Bhalla
Journal: Blood
Blood (2009) 114 (13): 2733–2743.
https://doi.org/10.1182/blood-2009-03-213496
Published: 2009
Includes: Supplemental data
Journal Articles

Cotreatment with BCL-2 antagonist sensitizes cutaneous T-cell lymphoma to lethal action of HDAC7-Nur77–based mechanism

Jianguang Chen, Warren Fiskus, Kelly Eaton, Pravina Fernandez, Yongchao Wang, Rekha Rao, Pearl Lee, Rajeshree Joshi, Yonghua Yang, Ravindra Kolhe, Ramesh Balusu, Prasanthi Chappa, Kavita Natarajan, Anand Jillella, Peter Atadja, Kapil N. Bhalla
Journal: Blood
Blood (2009) 113 (17): 4038–4048.
https://doi.org/10.1182/blood-2008-08-176024
Published: 2009
Includes: Supplemental data
Journal Articles

Molecular and biologic characterization and drug sensitivity of pan-histone deacetylase inhibitor–resistant acute myeloid leukemia cells

Warren Fiskus, Rekha Rao, Pravina Fernandez, Bryan Herger, Yonghua Yang, Jianguang Chen, Ravindra Kolhe, Aditya Mandawat, Yongchao Wang, Rajeshree Joshi, Kelly Eaton, Pearl Lee, Peter Atadja, Stephen Peiper, Kapil Bhalla
Journal: Blood
Blood (2008) 112 (7): 2896–2905.
https://doi.org/10.1182/blood-2007-10-116319
Published: 2008
Journal Articles

Targeting Histone Deacetylases and Unfolded Protein Mediated Endoplasmic Reticulum (ER) Stress as a Strategy Against Human Mantle Cell Lymphoma.

Rekha Rao, PhD, Warren Fiskus, PhD, Rajeshree Joshi, BS, Jianguang Chen, PhD, Pravina Fernandez, MS, Yongchao Wang, MS, Pearl Lee, BS, Anand Jillella, MD, Jianguo Tao, MD, Peter Atadja, PhD, Eduardo Sotomayor, MD, Kapil Bhalla, MD
Journal: Blood
Blood (2007) 110 (11): 1378.
https://doi.org/10.1182/blood.V110.11.1378.1378
Published: 2007
Journal Articles

Molecular Characterization and Drug-Sensitivity of Pan Histone Deacetylase Inhibitor Resistant Human Acute Myeloid Leukemia Cells.

Warren Fiskus, PhD, Rekha Rao, PhD, Pravina Fernandez, MS, Bryan Herger, PhD, Yonghua Yang, PhD, Jianguang Chen, PhD, Yongchao Wang, MS, Aditya Mandawat, BS, Pearl Lee, BS, Peter Atadja, PhD, Kapil Bhalla, MD
Journal: Blood
Blood (2007) 110 (11): 807.
https://doi.org/10.1182/blood.V110.11.807.807
Published: 2007