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Journal Articles

Cbl Controls the Expression of Axl and Lyn Tyrosine Kinases Mediating Resistance to Nilotinib in Chronic Myeloid Leukemia Cells

Claire Tregoat, Romain Gioia, Ph.D, Valérie Lagarde, Valerie Prouzet-Mauleon, Éric Lippert, MD, PhD, Audrey Sirvent, Serge Roche, Ph, D, Francois-Xavier Mahon, MD, PhD, Jean-Max Pasquet

Blood (2012) 120 (21): 3734.

https://doi.org/10.1182/blood.V120.21.3734.3734

Published: 2012

Journal Articles

Induced Pluripotent Stem Cells (iPSC) From Chronic Myeloid Leukemia: Study of BCR-ABL Addiction and Effect of Tyrosine Kinase Inhibitors,

Aurélie Bedel, Sr., Pharm D, PhD, Francois Moreau-Gaudry, MD, PhD, Jean- Max Pasquet, Sr., PhD, Miguel Taillepierre, Éric Lippert, MD, PhD, Valérie Lagarde, Hubert de Verneuil, MD, PhD, Emmanuel Richard, PhD, Francois-Xavier Mahon, MD, PhD

Blood (2011) 118 (21): 3754.

https://doi.org/10.1182/blood.V118.21.3754.3754

Published: 2011

Journal Articles

Quantitative phosphoproteomics revealed interplay between Syk and Lyn in the resistance to nilotinib in chronic myeloid leukemia cells

Romain Gioia, Cédric Leroy, Claire Drullion, Valérie Lagarde, Gabriel Etienne, Stéphanie Dulucq, Eric Lippert, Serge Roche, François-Xavier Mahon, Jean-Max Pasquet

Blood (2011) 118 (8): 2211–2221.

https://doi.org/10.1182/blood-2010-10-313692

Published: 2011

Includes: Supplemental data

Journal Articles

Quantitative Phosphoproteomics Identified a New Syk-Lyn-Axl Signalling Pathway Involved In Resistance to Nilotinib In Chronic Myeloid Leukemia Cells.

Romain Gioia, Ph, D, Cedric Leroy, Ph, D, Claire Drullion, Valérie Lagarde, Serge Roche, Ph, D, Francois-Xavier Mahon, MD, PhD, jean-Max Pasquet, Ph, D

Blood (2010) 116 (21): 3376.

https://doi.org/10.1182/blood.V116.21.3376.3376

Published: 2010

Journal Articles

Tyrosine Kinase Proteins profiling of Nilotinib Resistant Chronic Myelogenous Leukemia Cells Unravels a Tyrosine Kinase-Mediated Bypass.

Jean-Max Pasquet, Romain Gioia, Claire Drullion, Valerie Lagarde, Cedric Leroy, Serge Roche, Bruno Cardinaud, Francois-Xavier Mahon

Blood (2009) 114 (22): 2175.

https://doi.org/10.1182/blood.V114.22.2175.2175

Published: 2009

Journal Articles

Morphological Changes of Platelets from Patients with Von Willebrand Disease Types 2B and 3 Suggest That Von Willebrand Factor Intervenes in Platelet Formation from Megakaryocytes.

Paquita Nurden, Alan T Nurden, Jean-Max Pasquet, Jocelyne Enouf, Cécile Faurie-Bonnafous, Sylvia La Marca, Margherita Punzo, Luciano Baronciani, Augusto B. Federici

Blood (2008) 112 (11): 1238.

https://doi.org/10.1182/blood.V112.11.1238.1238

Published: 2008

Journal Articles

Defensine Alpha1 as a New Marker of Imatinib Resistance in Chronic Myelogenous Leukemia

Gabriel Etienne, Maryse Dupouy, Claudine Chollet, Jean-Max Pasquet, Eric Lippert, Josy Reiffers, François- Xavier Mahon, Beatrice Turcq

Blood (2008) 112 (11): 3180.

https://doi.org/10.1182/blood.V112.11.3180.3180

Published: 2008

Journal Articles

Lyn Kinase Overexpression Is One of the Mechanisms of Resistance to Nilotinib In Chronic Myeloid Leukemia

Francois-Xavi er Mahon, Sandrine Hayette, Valerie Lagarde, Franck E Nicolini, MD, PhD, Francis Belloc, Cedric Leroy, Serge Roche, Paul Manley, PhD, Coralie Belanger, Gabriel Etienne, Jean-Max Pasquet

Blood (2008) 112 (11): 3181.

https://doi.org/10.1182/blood.V112.11.3181.3181

Published: 2008

Journal Articles

The hematopoietic stem cell compartment of JAK2V617F-positive myeloproliferative disorders is a reflection of disease heterogeneity

Chloe James, Frederic Mazurier, Sabrina Dupont, Ronan Chaligne, Isabelle Lamrissi-Garcia, Micheline Tulliez, Eric Lippert, François-Xavier Mahon, Jean-Max Pasquet, Gabriel Etienne, François Delhommeau, Stephane Giraudier, William Vainchenker, Hubert de Verneuil

Blood (2008) 112 (6): 2429–2438.

https://doi.org/10.1182/blood-2008-02-137877

Published: 2008

Journal Articles

Normal Presence of Tissue Inhibitors of Matrix Metalloproteinases in Platelets of Patients with the Gray Platelet Syndrome Suggests a Novel Organization for These Secreted Proteins.

Julien Villeneuve, Anna Block, PhD, Caroline Le Bousse, PhD, Sebastien Lepreux, MD, Jean-Max Pasquet, PhD, Paquita Nurden, MD, PhD, Jean Ripoche, MD, Alan T. Nurden, PhD

Blood (2007) 110 (11): 2104.

https://doi.org/10.1182/blood.V110.11.2104.2104

Published: 2007

Journal Articles

Heat Shock Protein 70 over Expression Is Associated to Imatinib Resistance in Chronic Myelogenous Leukemia.

Marion Pocaly, Valérie Lagarde, Gabriel Etienne, Jean-Antoine Ribeil, Marc Bonneu, Stéphane Claverol, François Moreau-Gaudry, Olivier Hermine, Béatrice Turcq, François-Xavier Mahon, Jean-Max Pasquet

Blood (2005) 106 (11): 2005.

https://doi.org/10.1182/blood.V106.11.2005.2005

Published: 2005

Journal Articles

Severe Thrombocytopenia with Impaired Megakaryocytopoiesis in a Family with von Willebrand Disease Type 2B.

Paquita Nurden, MD, PhD, Najet Debili, PhD, William Vainchenker, MD, PhD, Jean-Max Pasquet, PhD, Regis Bobe, PhD, Raymonde Bredoux, PhD, Alan T. Nurden, PhD, Jocelyne Enouf, PhD

Blood (2005) 106 (11): 733.

https://doi.org/10.1182/blood.V106.11.733.733

Published: 2005

Journal Articles

Platelet-associated CD154 in immune thrombocytopenic purpura

Anne Solanilla, Jean-Max Pasquet, Jean-François Viallard, Cécile Contin, Christophe Grosset, Julie Déchanet-Merville, Maryse Dupouy, Marc Landry, Francis Belloc, Paquita Nurden, Patrick Blanco, Jean-François Moreau, Jean-Luc Pellegrin, Alan T. Nurden, Jean Ripoche

Blood (2005) 105 (1): 215–218.

https://doi.org/10.1182/blood-2003-07-2367

Published: 2005

Journal Articles

Functions of Thrombin Receptors in the Reversible Distribution of Platelet Glycoprotein Ib within Activated Platelets.

Han Yue, M.D.Ph.D., Jean-Max Pasquet, M.D.Ph.D., Alan Nurden, M.D.Ph.D., Ruan Changgeng, M.D.Ph.D.

Blood (2004) 104 (11): 3891.

https://doi.org/10.1182/blood.V104.11.3891.3891

Published: 2004

Journal Articles

Generation of Resistance Cell Lines to AMN107, a New Inhibitor of BCR-ABL and Its Effects on Cell Lines Sensitive and Resistant to Imatinib.

Francois-xavier Mahon, MD, PhD, Valerie Lagarde, Paul W. Manley, PhD, Jean-Max Pasquet, PhD, Beatrice Turcq, PhD, Josy Reiffers, MD

Blood (2004) 104 (11): 4670.

https://doi.org/10.1182/blood.V104.11.4670.4670

Published: 2004

Journal Articles

The Proteome Analysis of an Imatinib-Resistant Cell Line Identifies Changes in Molecular Chaperones Such as Heat Shock Proteins (Hsp): A Possible New Mechanism of Imatinib Resistance.

Jean-Max Pasquet, PhD, Marion Pocaly, Valérie Lagarde, Béatrice Turcq, PhD, Josy Reiffers, MD, Junia V. Melo, MD PhD, Francois-Xavier Mahon, MD PhD

Blood (2004) 104 (11): 1981.

https://doi.org/10.1182/blood.V104.11.1981.1981

Published: 2004

Journal Articles

Severe deficiency of glycoprotein VI in a patient with gray platelet syndrome

Paquita Nurden, Martine Jandrot-Perrus, Robert Combrié, Joelle Winckler, Veronique Arocas, Christelle Lecut, Jean-Max Pasquet, Thomas J. Kunicki, Alan T. Nurden

Blood (2004) 104 (1): 107–114.

https://doi.org/10.1182/blood-2003-11-3842

Published: 2004

Journal Articles

Fyn and Lyn phosphorylate the Fc receptor γ chain downstream of glycoprotein VI in murine platelets, and Lyn regulates a novel feedback pathway

Lynn S. Quek, Jean-Max Pasquet, Ingeborg Hers, Richard Cornall, Graham Knight, Michael Barnes, Margaret L. Hibbs, Ashley R. Dunn, Clifford A. Lowell, Steve P. Watson

Blood (2000) 96 (13): 4246–4253.

https://doi.org/10.1182/blood.V96.13.4246

Published: 2000

Journal Articles

Thrombopoietin potentiates collagen receptor signaling in platelets through a phosphatidylinositol 3-kinase–dependent pathway

Jean-max Pasquet, Barbara S. Gross, Marie-Pierre Gratacap, Lynn Quek, Sophie Pasquet, Bernard Payrastre, Gijsbert van Willigen, Joanne C. Mountford, Steve P. Watson

Blood (2000) 95 (11): 3429–3434.

https://doi.org/10.1182/blood.V95.11.3429

Published: 2000

NARROW

Cbl Controls the Expression of Axl and Lyn Tyrosine Kinases Mediating Resistance to Nilotinib in Chronic Myeloid Leukemia Cells

Induced Pluripotent Stem Cells (iPSC) From Chronic Myeloid Leukemia: Study of BCR-ABL Addiction and Effect of Tyrosine Kinase Inhibitors,

Quantitative phosphoproteomics revealed interplay between Syk and Lyn in the resistance to nilotinib in chronic myeloid leukemia cells

Quantitative Phosphoproteomics Identified a New Syk-Lyn-Axl Signalling Pathway Involved In Resistance to Nilotinib In Chronic Myeloid Leukemia Cells.

Tyrosine Kinase Proteins profiling of Nilotinib Resistant Chronic Myelogenous Leukemia Cells Unravels a Tyrosine Kinase-Mediated Bypass.

Morphological Changes of Platelets from Patients with Von Willebrand Disease Types 2B and 3 Suggest That Von Willebrand Factor Intervenes in Platelet Formation from Megakaryocytes.

Defensine Alpha1 as a New Marker of Imatinib Resistance in Chronic Myelogenous Leukemia

Lyn Kinase Overexpression Is One of the Mechanisms of Resistance to Nilotinib In Chronic Myeloid Leukemia

The hematopoietic stem cell compartment of JAK2V617F-positive myeloproliferative disorders is a reflection of disease heterogeneity

Normal Presence of Tissue Inhibitors of Matrix Metalloproteinases in Platelets of Patients with the Gray Platelet Syndrome Suggests a Novel Organization for These Secreted Proteins.

Heat Shock Protein 70 over Expression Is Associated to Imatinib Resistance in Chronic Myelogenous Leukemia.

Severe Thrombocytopenia with Impaired Megakaryocytopoiesis in a Family with von Willebrand Disease Type 2B.

Platelet-associated CD154 in immune thrombocytopenic purpura

Functions of Thrombin Receptors in the Reversible Distribution of Platelet Glycoprotein Ib within Activated Platelets.

Generation of Resistance Cell Lines to AMN107, a New Inhibitor of BCR-ABL and Its Effects on Cell Lines Sensitive and Resistant to Imatinib.

The Proteome Analysis of an Imatinib-Resistant Cell Line Identifies Changes in Molecular Chaperones Such as Heat Shock Proteins (Hsp): A Possible New Mechanism of Imatinib Resistance.

Severe deficiency of glycoprotein VI in a patient with gray platelet syndrome

Fyn and Lyn phosphorylate the Fc receptor γ chain downstream of glycoprotein VI in murine platelets, and Lyn regulates a novel feedback pathway

Thrombopoietin potentiates collagen receptor signaling in platelets through a phosphatidylinositol 3-kinase–dependent pathway

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American Society of Hematology

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American Society of Hematology

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