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Journal Articles

A Phase II Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial to Evaluate the Efficacy of Cmvpepvax for Preventing CMV Reactivation/Disease after Matched Related/Unrelated Donor Hematopoietic Cell Transplant

Blood (2021) 138 (Supplement 1): 2887.

https://doi.org/10.1182/blood-2021-153312

Published: 2021

Journal Articles

Vaccination of Hematopoietic Stem Cell (HCT) Donors with Triplex, a Novel Cytomegalovirus Vaccine: Safety, Feasibility and Adoptive Transfer of Protective CMV-Specific T Cells in HCT Recipients

Ryotaro Nakamura, MD, Corinna La Rosa, PhD, Ibrahim Aldoss, MD, Qiao Zhou, B.S., Chetan Raj Lingaraju, M.S., Joy Martinez, M.S., Teodora Kaltcheva, PhD, Don J. Diamond, PhD

Blood (2020) 136 (Supplement 1): 33.

https://doi.org/10.1182/blood-2020-141811

Published: 2020

Journal Articles

Large-Scale Manufacturing of CMV-CD19CAR T Cells and Characterization of Their Biologic and Immunologic Properties

Xiuli Wang, PhD, Miriam Walter, Ryan Urak, Laura Lim, Vibhuti Vyas, MS, Sally Mokhtari, PhD, Don J. Diamond, PhD, Angelo Cardoso, PhD, John Zaia, MD, Stephen J. Forman, MD, Ryotaro Nakamura, MD

Blood (2019) 134 (Supplement_1): 3247.

https://doi.org/10.1182/blood-2019-131843

Published: 2019

Journal Articles

MVA vaccine encoding CMV antigens safely induces durable expansion of CMV-specific T cells in healthy adults

Corinna La Rosa, Jeff Longmate, Joy Martinez, Qiao Zhou, Teodora I. Kaltcheva, Weimin Tsai, Jennifer Drake, Mary Carroll, Felix Wussow, Flavia Chiuppesi, Nicola Hardwick, Sanjeet Dadwal, Ibrahim Aldoss, Ryotaro Nakamura, John A. Zaia, Don J. Diamond

Blood (2017) 129 (1): 114–125.

https://doi.org/10.1182/blood-2016-07-729756

Published: 2017

Includes: Supplemental data

Journal Articles

Safety, Maximum Tolerated Dose and Immunogenicity of CMV-MVA-Triplex in Healthy Volunteers with or without Prior Immunity to CMV and Vaccinia

Don J. Diamond, PhD, Corinna La Rosa, PhD, Jeffrey Longmate, PhD, Joy Martinez, Qiao Zhou, Theodora Kaltcheva, PhD, Jennifer Drake, Mary Carroll, Sanjeet Dadwal, MD, Ibrahim Aldoss, MD, Ryotaro Nakamura, MD, John A. Zaia, MD

Blood (2015) 126 (23): 3108.

https://doi.org/10.1182/blood.V126.23.3108.3108

Published: 2015

Journal Articles

CMV Reactivation is Associated with Reduced Relapse Risk, Better Disease-Free Survival and Expansion of Adaptive NK Cells after Reduced Intensity Hematopoietic Cell Transplantation

Frank Cichocki, PhD, Zachary B. Davis, PhD, Todd E. DeFor, MS, Sarah A. Cooley, MD MS, Yenan T. Bryceson, PhD, Don J. Diamond, PhD, Bruce R. Blazar, MD, Claudio Brunstein, MD, John E. Wagner, MD, Michael R. Verneris, MD, Daniel J. Weisdorf, MD, Jeffrey S. Miller, MD

Blood (2014) 124 (21): 668.

https://doi.org/10.1182/blood.V124.21.668.668

Published: 2014

Journal Articles

Clonal Expansion of Adaptive NK Cells and NKG2C + CD57 + KIR-Expressing T Cells from Sibling, but Not Umbilical Cord Blood, Grafts Is Induced By Recipient Latent CMV and Is Associated with Protection Against CMV Reactivation

Zachary B. Davis, PhD, Frank Cichocki, PhD, Martin Felices, PhD, Rose Wangen, Todd E. DeFor, MS, Sarah A. Cooley, MD MS, Yenan T. Bryceson, PhD, Don J. Diamond, PhD, Claudio Brunstein, MD, Bruce R. Blazar, MD, John E. Wagner, MD, Daniel J. Weisdorf, MD, Amir Horowitz, Lisbeth A Guethlein, Peter Parham, PhD, Michael R. Verneris, MD, Jeffrey S. Miller, MD

Blood (2014) 124 (21): 181.

https://doi.org/10.1182/blood.V124.21.181.181

Published: 2014

Journal Articles

Randomized Trial of a Novel CMV Vaccine (CMVPepVax) after Allogeneic HCT: Elevated CMV-Specific Immune Response, Reduction in Chronic GvHD and CMV Reactivation Only in Vaccine Arm Patients

Ryotaro Nakamura, MD, Corinna La Rosa, PhD, Jeff Longmate, PhD, Margaret O'Donnell, MD FRCPC, Ji-Lian Cai, MD, Len Farol, MD, Amandeep Salhotra, MD, David S Snyder, MD, Jennifer Drake, Cynthia Slape, James Merson, PhD, John A Zaia, MD, Stephen J. Forman, Don J. Diamond, PhD

Blood (2014) 124 (21): 183.

https://doi.org/10.1182/blood.V124.21.183.183

Published: 2014

Journal Articles

Suppressing Immunosuppressive Pathways by RNA Interference Synergizes with Tumor Antigen Vaccines Causing Long-Term Regression of Established Subcutaneous Lymphomas

Edwin R Manuel, Ph.D., Celine Blache, Ph.D., Teodora Kaltcheva, PhD, Fernanda Castro, Ph.D., Don J. Diamond, PhD

Blood (2011) 118 (21): 106.

https://doi.org/10.1182/blood.V118.21.106.106

Published: 2011

Journal Articles

Detection and Characterization of Antigen-Driven CD8 + T Lymphocytes Specific for Wilms' Tumor Antigen in Patients with Non-Hodgkin Lymphoma

Ryotaro Nakamura, MD, Anna Israyelyan, MD, PhD, Corinna La Rosa, PhD, Weimin Tsai, BS, Teodora Kaltcheva, PhD, Tumul Srivastava, PhD, Jessica Lo, BS, Lia Aquino, Jianqiang Li, PhD, Young Kim, MD, Joycelynne Palmer, PhD, David Senitzer, PhD, John Zaia, MD, Stephen J. Forman, MD, Don J. Diamond, PhD

Blood (2011) 118 (21): 953.

https://doi.org/10.1182/blood.V118.21.953.953

Published: 2011

Journal Articles

Characterization of immunologic properties of a second HLA-A2 epitope from a granule protease in CML patients and HLA-A2 transgenic mice

Simon F. Lacey, Corinna La Rosa, Teodora Kaltcheva, Tumul Srivastava, Aprille Seidel, Wendi Zhou, Ravindra Rawal, Katharine Hagen, Aparna Krishnan, Jeff Longmate, Helen A. Andersson, Lisa St. John, Ravi Bhatia, Vinod Pullarkat, Stephen J. Forman, Laurence J. N. Cooper, Jeffrey Molldrem, Don J. Diamond

Blood (2011) 118 (8): 2159–2169.

https://doi.org/10.1182/blood-2011-04-349951

Published: 2011

Journal Articles

Breaking Immune Tolerance to Granule Proteases with Full-Length Antigen Vaccine in Humanized Transgenic Mice Reveals Alternative Antigen Processing and Immunodominance Heirarchy Applicable to Clinical Immunotherapy.

J. Diamond Don, Ph.D, Wendi Zhou, Ph.D, Tumul Srivastava, Ph.D, Ravindra Rawal, Ph.D, Katharine Hagan, Helen A Andersson, Ph.D, J. N. Cooper Laurence, M.D., Jeffrey J. Molldrem, M.D., Simon F. Lacey, PhD, BSc

Blood (2009) 114 (22): 2054.

https://doi.org/10.1182/blood.V114.22.2054.2054

Published: 2009

Journal Articles

Impact of donor CMV status on viral infection and reconstitution of multifunction CMV-specific T cells in CMV-positive transplant recipients

Wendi Zhou, Jeff Longmate, Simon F. Lacey, Joycelynne M. Palmer, Ghislaine Gallez-Hawkins, Lia Thao, Ricardo Spielberger, Ryotaro Nakamura, Stephen J. Forman, John A. Zaia, Don J. Diamond

Blood (2009) 113 (25): 6465–6476.

https://doi.org/10.1182/blood-2009-02-203307

Published: 2009

Includes: Supplemental data

Journal Articles

Impact of Donor Serostatus on CMV Reactivation and Reconstitution of Multi-Function CMV-Specific T Cells in CMV-Positive Transplant Recipients

Wendi Zhou, PHD, Jeff Longmate, PHD, Simon F Lacey, PHD, Joycelynne Palmer, PHD, Ghislaine Gallez-Hawkins, MSc, Lia Thao, BSc, Ryotaro Nakamura, MD, Ricardo Spielberger, MD, Stephen J. Forman, MD, John A. Zaia, MD, Don J. Diamond, PHD

Blood (2008) 112 (11): 4339.

https://doi.org/10.1182/blood.V112.11.4339.4339

Published: 2008

Journal Articles

Pre-Clinical Development of a Subunit Vaccine Expressing an IE1-IE2 Fusion Protein of HCMV.

Zhongde Wang, PHD, Wendy Zhou, PHD, MD, Tumul Srivastava, PHD, Corinna La Rosa, PHD, Stephen J. Forman, MD, John A. Zaia, MD, Don J. Diamond, PhD

Blood (2007) 110 (11): 165.

https://doi.org/10.1182/blood.V110.11.165.165

Published: 2007

Journal Articles

Multicytokine and Polyfunctional CMV-Specific T Cells Are Associated with Stem Cell Transplant Donor CMV Serostatus.

Wendi Zhou, PhD, Jeffrey Longmate, PhD, Joycelynne Palmer, PhD, Simon F. Lacey, PhD, Ghislaine A. Hawkins, MS, Ricardo Spielberger, MD, Stephen J. Forman, MD, John A. Zaia, MD, Don J. Diamond, PhD

Blood (2007) 110 (11): 4992.

https://doi.org/10.1182/blood.V110.11.4992.4992

Published: 2007

Journal Articles

Functional Comparison and Longitudinal Assessment of Tri-Functional T-Cells Recognizing CMV pp65 and IE-1 Polypeptides in Hematopoietic Stem Cell and Solid Organ Transplant Recipients.

Don J. Diamond, PhD, Simon F. Lacey, PhD, Corinna La Rosa, PhD, Wendy Zhou, PHD,MD, Ghislaine Gallez-Hawkins, MS, Lia Thao, MS, Jeff Longmate, PhD, Ajit Limaye, MD, Ricardo Spielberger, MD, Stephen J. Forman, MD, John A. Zaia, MD

Blood (2006) 108 (11): 2936.

https://doi.org/10.1182/blood.V108.11.2936.2936

Published: 2006

Journal Articles

Vaccine Properties of a Novel Marker Gene-Free Recombinant Modified Vaccinia Ankara (MVA) Expressing Immunodominant CMV Antigens.

Don J. Diamond, PhD, Zhongde Wang, PhD, Corinna La Rosa, PhD, Tumul Srivastava, PHD, Wendy Zhou, MD, PHD, Zhongqi Li, PhD, Heang Ly, Tamineh Akbarnejad, MS, Aparna Krishnan, MS, William J. Britt, MD

Blood (2006) 108 (11): 2858.

https://doi.org/10.1182/blood.V108.11.2858.2858

Published: 2006

Journal Articles

CMV Immunity Status in Older (>50 Years Old) Subjects after Non-Myeloablative or Reduced Intensity Regimen for Hematopoietic Cell Transplantation (HCT): A Comparison with a Younger Cohort after Ablative HCT.

Ghislaine Gallez-Hawkins, MSc, Lia Thao, Simon F. Lacey2, PhD, Joybelle Martinez, Anne E. Franck, Xiuli Li, Norma A. Lomeli, Ricardo Spielberger, MD, Ryotaro Nakamura, MD, Stephen J. Forman, MD, Don J. Diamond, PhD, John A. Zaia, MD

Blood (2005) 106 (11): 3246.

https://doi.org/10.1182/blood.V106.11.3246.3246

Published: 2005

Journal Articles

Development and Immunologic Characterization of Multi-Antigen Expressing Attenuated Poxviruses for Immunotherapy of CMV Infection in HSCT Recipients.

Don J. Diamond, PhD, Zhongde Wang, PhD, Corinna La Rosa, PhD, Goetz U. Grigoleit, MD, Angelo Mandarino, PhD, Simon F. Lacey, PhD, Holger Ludwig, PhD, William J. Britt, MD, Gerd Sutter, PhD, Hermann Einsele, MD

Blood (2005) 106 (11): 480.

https://doi.org/10.1182/blood.V106.11.480.480

Published: 2005

NARROW

A Phase II Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial to Evaluate the Efficacy of Cmvpepvax for Preventing CMV Reactivation/Disease after Matched Related/Unrelated Donor Hematopoietic Cell Transplant

Vaccination of Hematopoietic Stem Cell (HCT) Donors with Triplex, a Novel Cytomegalovirus Vaccine: Safety, Feasibility and Adoptive Transfer of Protective CMV-Specific T Cells in HCT Recipients

Large-Scale Manufacturing of CMV-CD19CAR T Cells and Characterization of Their Biologic and Immunologic Properties

MVA vaccine encoding CMV antigens safely induces durable expansion of CMV-specific T cells in healthy adults

Safety, Maximum Tolerated Dose and Immunogenicity of CMV-MVA-Triplex in Healthy Volunteers with or without Prior Immunity to CMV and Vaccinia

CMV Reactivation is Associated with Reduced Relapse Risk, Better Disease-Free Survival and Expansion of Adaptive NK Cells after Reduced Intensity Hematopoietic Cell Transplantation

Clonal Expansion of Adaptive NK Cells and NKG2C + CD57 + KIR-Expressing T Cells from Sibling, but Not Umbilical Cord Blood, Grafts Is Induced By Recipient Latent CMV and Is Associated with Protection Against CMV Reactivation

Randomized Trial of a Novel CMV Vaccine (CMVPepVax) after Allogeneic HCT: Elevated CMV-Specific Immune Response, Reduction in Chronic GvHD and CMV Reactivation Only in Vaccine Arm Patients

Suppressing Immunosuppressive Pathways by RNA Interference Synergizes with Tumor Antigen Vaccines Causing Long-Term Regression of Established Subcutaneous Lymphomas

Detection and Characterization of Antigen-Driven CD8 + T Lymphocytes Specific for Wilms' Tumor Antigen in Patients with Non-Hodgkin Lymphoma

Characterization of immunologic properties of a second HLA-A2 epitope from a granule protease in CML patients and HLA-A2 transgenic mice

Breaking Immune Tolerance to Granule Proteases with Full-Length Antigen Vaccine in Humanized Transgenic Mice Reveals Alternative Antigen Processing and Immunodominance Heirarchy Applicable to Clinical Immunotherapy.

Impact of donor CMV status on viral infection and reconstitution of multifunction CMV-specific T cells in CMV-positive transplant recipients

Impact of Donor Serostatus on CMV Reactivation and Reconstitution of Multi-Function CMV-Specific T Cells in CMV-Positive Transplant Recipients

Pre-Clinical Development of a Subunit Vaccine Expressing an IE1-IE2 Fusion Protein of HCMV.

Multicytokine and Polyfunctional CMV-Specific T Cells Are Associated with Stem Cell Transplant Donor CMV Serostatus.

Functional Comparison and Longitudinal Assessment of Tri-Functional T-Cells Recognizing CMV pp65 and IE-1 Polypeptides in Hematopoietic Stem Cell and Solid Organ Transplant Recipients.

Vaccine Properties of a Novel Marker Gene-Free Recombinant Modified Vaccinia Ankara (MVA) Expressing Immunodominant CMV Antigens.

CMV Immunity Status in Older (>50 Years Old) Subjects after Non-Myeloablative or Reduced Intensity Regimen for Hematopoietic Cell Transplantation (HCT): A Comparison with a Younger Cohort after Ablative HCT.

Development and Immunologic Characterization of Multi-Antigen Expressing Attenuated Poxviruses for Immunotherapy of CMV Infection in HSCT Recipients.

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