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Ryan Urak
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Journal Articles

Generation of Bi-Specific Chimeric Antigen Receptor (CAR) T Cell Therapy for the Treatment of AIDS-Related B Cell Malignancies from Healthy Donors and HIV Patients

Saghar Pahlavanneshan, Ryan Urak, Ryotaro Nakamura, John Zaia, John H. Baird, Mary C Clark, Stephen J. Forman, Xiuli Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 6822.
https://doi.org/10.1182/blood-2023-173757
Published: 2023
Journal Articles

Antimetabolite Resistant CAR T Cells through the Suppression of Hypoxanthine Phosphoribosyltransferase 1

Ryan Urak, Stephen J Forman, Xiuli Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 10648–10649.
https://doi.org/10.1182/blood-2022-169583
Published: 2022
Journal Articles

Development of Humanized CD19-Chimeric Antigen Receptor for B Cell Malignancy

Vibhuti Vyas, Lawrence Stern, Laura Lim, Christian Huynh, Ryan Urak, John C Williams, Stephen J Forman, Christine E Brown, Xiuli Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 12704–12705.
https://doi.org/10.1182/blood-2022-169803
Published: 2022
Journal Articles

Dexamethasone Enhanced CAR T Cell Persistence and Function through Upregulation of Interleukin 7 Receptor

Ryan Urak, Ashlie Munoz, Hui-Ju Hsieh, Ellie Taus, Stephen J Forman, Xiuli Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 1715.
https://doi.org/10.1182/blood-2021-153507
Published: 2021
Journal Articles

Developing a Safer Anti-CD44v6 Chimeric Antigen Receptor T Cell Against Hematological Cancers By Mitigating on-Target Off-Tumor Toxicity

Dennis Awuah, Lawrence Stern, Ian Schrack, Tae Yoon Kim, Joseph Cohen, Ryan Urak, Christian Huynh, Wen-Chung Chang, Stephen J Forman, Xiuli Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 2796.
https://doi.org/10.1182/blood-2021-153927
Published: 2021
Journal Articles

Single-Cell Analysis By Mass Cytometry Reveals CD19 CAR T Cell Spatiotemporal Plasticity in Patients

Lior Goldberg, Eric R Haas, Vibhuti Vyas, Ryan Urak, Stephen J Forman, Xiuli Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 2794.
https://doi.org/10.1182/blood-2021-153444
Published: 2021
Journal Articles

Large-Scale Manufacturing of CMV-CD19CAR T Cells and Characterization of Their Biologic and Immunologic Properties

Xiuli Wang, PhD, Miriam Walter, Ryan Urak, Laura Lim, Vibhuti Vyas, MS, Sally Mokhtari, PhD, Don J. Diamond, PhD, Angelo Cardoso, PhD, John Zaia, MD, Stephen J. Forman, MD, Ryotaro Nakamura, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3247.
https://doi.org/10.1182/blood-2019-131843
Published: 2019
Journal Articles

The Cerebroventricular Environment Reprograms Locally Infused CAR T Cells for Superior Activity Against Both CNS and Systemic B Cell Lymphoma

Xiuli Wang, PhD, Christian Huynh, Ryan Urak, Miriam Walter, Lihong Weng, MD, Laura Lim, Vibhuti Vyas, Brenda Aguilar, Alfonso Brito, Aniee Sarkissian, Achini Bandara, PhD, Elizabeth E Budde, MD PhD, Leslie Popplewell, MD, Tanya Siddiqi, MD, Christine Brown, PhD, Stephen J Forman
Journal: Blood
Blood (2018) 132 (Supplement 1): 965.
https://doi.org/10.1182/blood-2018-99-119335
Published: 2018
Journal Articles

Lenalidomide Enhances the Function of CS1 Chimeric Antigen Receptor Redirected-T Cells Against Multiple Myeloma

Xiuli Wang, MD PhD, Ryan Urak, MS, Miriam Walter, MS, Lihong Weng, MD, Laura Lim, BS, Ching Wong, BS, Wen-Chung Chang, MS, Sandra H. Thomas, PhD, Myo Htut, MD, Amrita Krishnan, MD, Stephen J. Forman, MD
Journal: Blood
Blood (2016) 128 (22): 812.
https://doi.org/10.1182/blood.V128.22.812.812
Published: 2016
Journal Articles

New Therapeutic Approach for Central Nervous System Lymphoma By Intracerebroventricular Delivery of CD19CAR T Cells

Xiuli Wang, MD PhD, Ryan Urak, MS, Walter Miriam, MS, Laura Lim, BS, Brenda Aguilar, BS, Alfonso Brito, BS, Aniee Sarkissian, BS, Christine Brown, PhD, Sandra H. Thomas, PhD, Leslie Popplewell, MD, Lihua E. Budde, MD PhD, Stephen J. Forman, MD
Journal: Blood
Blood (2016) 128 (22): 2161.
https://doi.org/10.1182/blood.V128.22.2161.2161
Published: 2016
Journal Articles

Ex Vivo AKT Inhibition Promotes the Generation of Potent CD19CAR T Cells for Adoptive Immunotherapy

Ryan Urak, MS, ChingLam Wong, BS, Wen-Chung Chang, MS, Elizabeth E. Budde, MD PhD, Christine Brown, PhD, Sandra H. Thomas, PhD, Stephen J. Forman, MD, Xiuli Wang, PhD
Journal: Blood
Blood (2015) 126 (23): 3086.
https://doi.org/10.1182/blood.V126.23.3086.3086
Published: 2015
Journal Articles

Phase I Studies of Cellular Immunotherapy Using Central Memory Derived-CD19-Specific T Cells Following Autologous Stem Cell Transplantation for Patients with High-Risk Intermediate Grade B-Lineage Non-Hodgkin Lymphoma

Leslie Popplewell, MD, Xiuli Wang, PhD, Araceli Naranjo, BS, Suzette Blanchard, PhD, Jamie Wagner, BS, ChingLam Wong, BS, Ryan Urak, MS, Wen-Chung Chang, MS, Samer K Khaled, MD, Tanya Siddiqi, MD, Elizabeth E. Budde, MD PhD, Jingying Xu, PhD, Brenda Chang, BS, Sandra H. Thomas, PhD, Stanley R. Riddell, MD, Christine Brown, PhD, Michael C Jensen, MD, Stephen J. Forman, MD
Journal: Blood
Blood (2015) 126 (23): 930.
https://doi.org/10.1182/blood.V126.23.930.930
Published: 2015
Journal Articles

CS-1 Re-Directed Central Memory T Cell Therapy for Multiple Myeloma

Xiuli Wang, PhD, ChingLam W Wong, BS, Ryan Urak, MS, Wen-Chung Chang, MS, Elizabeth E. Budde, MD PhD, Christine Brown, PhD, Stephen J. Forman, MD
Journal: Blood
Blood (2014) 124 (21): 1114.
https://doi.org/10.1182/blood.V124.21.1114.1114
Published: 2014
Journal Articles

Targeting Of Leukemia Stem Cells By Interfering With Niches Using CD44 Variant 6 Chimeric Antigen Receptor Redirected Central Memory T Cells

Xiuli Wang, PhD, ChingLam W Wong, BS, Ryan Urak, MS, Armen Mardiros, MS, Wen-Chung Chang, MS, Ellie Taus, BS, Lihua E Budde, MD, PhD, Julie R Ostberg, Ph.D, Christine Brown, PhD, Stephen J. Forman, MD
Journal: Blood
Blood (2013) 122 (21): 4497.
https://doi.org/10.1182/blood.V122.21.4497.4497
Published: 2013