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Journal Articles

Endothelial Protein C Receptor CD201 Enables Identification of Transplantable Mouse Hematopoietic Stem Cells in Inflammatory Conditions Unlike SCA1

Kavita Bisht, Svetlana Shatunova, Valerie Barbier, Ingrid G Winkler, Jean-Pierre Levesque

Blood (2024) 144 (Supplement 1): 1286.

https://doi.org/10.1182/blood-2024-199946

Published: 2024

Journal Articles

Endotoxemia As Possible Cause of Inflammatory Bowel Diseases-Associated Anemia

Kavita Bisht, Yoon-Kyo An, Svetlana Shatunova, Ran Wang, Valerie Barbier, Rabina Giri, Anna Amiss, Yifu Tang, Kylie Alexander, Susan Millard, Ingrid G Winkler, Allison Pettit, Jakob Begun, Jean-Pierre Levesque

Blood (2024) 144 (Supplement 1): 166.

https://doi.org/10.1182/blood-2024-193349

Published: 2024

Journal Articles

Oncostatin M Is a Novel Niche Factor That Restrains Hematopoietic Stem Cell Mobilization in Response to G-CSF and CXCR4 Antagonist Plerixafor

Kavita Bisht, PhD, Crystal McGirr, Kylie A Alexander, Whitney Fleming, Natalie Sims, Gerhard Müller- Newen, Ingrid G Winkler, PhD, Jean-Pierre Levesque, PhD

Blood (2019) 134 (Supplement_1): 4469.

https://doi.org/10.1182/blood-2019-127431

Published: 2019

Journal Articles

Blocking Vascular Niche E-Selectin Dampens AML Stem Cell Regeneration/Survival Potential In Vivo By Inhibiting MAPK/ERK and PI3K/AKT Signalling Pathways

Ingrid G Winkler, PhD, Valerie Barbier, Masters, Joshua Tay, PhD, Jean-Pierre Levesque, PhD, John L. Magnani, PhD, Corrine E Fiveash, BSc(Hons), Johanna D Erbani

Blood (2019) 134 (Supplement_1): 2657.

https://doi.org/10.1182/blood-2019-132212

Published: 2019

Journal Articles

CD162 Is a Key E-Selectin Receptor Promoting Acute Myeloid Leukemia Chemo-Resistance in the Bone Marrow Niche

Johanna D Erbani, Joshua Tay, PhD, Valerie Barbier, Masters, Jean-Pierre Levesque, PhD, John L. Magnani, PhD, Ingrid G Winkler, PhD

Blood (2019) 134 (Supplement_1): 907.

https://doi.org/10.1182/blood-2019-132233

Published: 2019

Journal Articles

Prostaglandin I 2 in the Endosteal Bone Marrow Niche As a Novel Regulator of Hematopoietic Stem Cells

Joshua Tay, PhD, Jean-Pierre Levesque, PhD, Falak Helwani, PhD, Gareth Price, PhD, Bianca Nowlan, Masters, Valerie Barbier, Masters, Ingrid G Winkler, PhD

Blood (2018) 132 (Supplement 1): 2575.

https://doi.org/10.1182/blood-2018-99-115869

Published: 2018

Journal Articles

Vascular E-Selectin Acts As a Gatekeeper Inducing Commitment and Loss of Self-Renewal in HSC Transmigrating through the Marrow Vasculature

Ingrid G Winkler, PhD, Valerie Barbier, Masters, Jessica Lowe, BSc(Hons), Joshua Tay, PhD, John L Magnani, PhD, Paula Marlton, Anthony K Mills, FRACP, FRCPA, MBBS, Andrew Perkins, MBBS, PhD FRCPA, FRACP, Corrine E Fiveash, BSc(Hons), Johanna M Erbani, PhDstudent, Jean-Pierre Levesque, PhD

Blood (2018) 132 (Supplement 1): 4552.

https://doi.org/10.1182/blood-2018-99-120376

Published: 2018

Journal Articles

Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment

Simranpreet Kaur, Liza J. Raggatt, Susan M. Millard, Andy C. Wu, Lena Batoon, Rebecca N. Jacobsen, Ingrid G. Winkler, Kelli P. MacDonald, Andrew C. Perkins, David A. Hume, Jean-Pierre Levesque, Allison R. Pettit

Blood (2018) 132 (7): 735–749.

https://doi.org/10.1182/blood-2018-01-829663

Published: 2018

Includes: Supplemental data

Journal Articles

Vascular E-Selectin Mediates Chemo-Resistance in Acute Myeloid Leukemia Initiating Cells Via Canonical Receptors PSGL-1 (CD162) and Hcell (CD44) and AKT Signaling

Ingrid G Winkler, PhD, Johanna M Erbani, PhDstudent, Valerie Barbier, Masters, Julie M Davies, PhD, Joshua Tay, PhDstudent, Corrine E Fiveash, BSc(Hons), Jessica Lowe, BSc(Hons), Michael Tallack, MDPhD, John L Magnani, PhD, Jean-Pierre Levesque, PhD

Blood (2017) 130 (Supplement 1): 793.

https://doi.org/10.1182/blood.V130.Suppl_1.793.793

Published: 2017

Journal Articles

Macrophage Involvement in the Response of Acute Myeloid Leukaemia to Chemotherapy

Thomas Keech, BSc, Crystal McGirr, Ingrid G Winkler, PhD, Jean-Pierre Levesque, PhD

Blood (2017) 130 (Supplement 1): 5069.

https://doi.org/10.1182/blood.V130.Suppl_1.5069.5069

Published: 2017

Journal Articles

Suppression of Medullar Erythropoiesis in Response to Bacterial Lipopolysaccharides (LPS) Involves Two Distinct TLR4-Dependent Mechanisms with Contrasted Requirements for G-CSF Receptors

Kavita Bisht, PhD, Rebecca Jacobsen, BSc, Bianca Nowlan, Crystal McGirr, Marion Brunck, Thomas Keech, Ingrid G Winkler, PhD, Jean-Pierre Levesque, PhD

Blood (2016) 128 (22): 546.

https://doi.org/10.1182/blood.V128.22.546.546

Published: 2016

Journal Articles

Vascular E-Selectin Protects Leukemia Cells from Chemotherapy By Directly Activating Pro-Survival NF-Kb Signalling - Therapeutic Blockade of E-Selectin Dampens NF-Kb Activation

Ingrid G Winkler, PhD, Valerie Barbier, Micheal Ward, PhD, Michael Tallack, PhD MD, Jessica Lowe, Julie Davies, Johanna Erbani, John L Magnani, PhD, Jean-Pierre Levesque, PhD

Blood (2016) 128 (22): 2823.

https://doi.org/10.1182/blood.V128.22.2823.2823

Published: 2016

Journal Articles

Therapeutic Blockade of Macrophage Colony Stimulating Factor (CSF-1) Delays AML Progression in Mice In Vivo

Sal Lee Goh, PhDstudent, Jean-Pierre Levesque, PhD, Allison R Petitt, PhD, Valarie Barbier, Degree, Ingrid G Winkler, PhD

Blood (2016) 128 (22): 2835.

https://doi.org/10.1182/blood.V128.22.2835.2835

Published: 2016

Journal Articles

Mobilization of CD8 + Central Memory T-Cells with Enhanced Reconstitution Potential in Mice By a Combination of G-CSF and GMI-1271-Mediated E-Selectin Blockade

Ingrid G Winkler, PhD, Valerie Barbier, Kristen J Radford, PhD, Julie M Davies, PhD, Jean-Pierre Levesque, PhD, Theodore A.G. Smith, PhD, William E. Fogler, PhD, John L Magnani, PhD

Blood (2015) 126 (23): 512.

https://doi.org/10.1182/blood.V126.23.512.512

Published: 2015

Journal Articles

Mobilisation of Reconstituting HSC Is Boosted By Synergy Between G-CSF and E-Selectin Antagonist GMI-1271.

Ingrid G Winkler, PhD, Valerie Barbier, Andrew C Perkins, MDPhD, John L. Magnani, PhD, Jean-Pierre Levesque, PhD

Blood (2014) 124 (21): 317.

https://doi.org/10.1182/blood.V124.21.317.317

Published: 2014

Journal Articles

Vascular Niche E-Selectin Protects Acute Myeloid Leukaemia Stem Cells from Chemotherapy

Ingrid G Winkler, PhD, Valerie Barbier, Diwakar R Pattabiraman, PhD, Thomas J Gonda, PhD, John L. Magnani, PhD, Jean-Pierre Levesque, PhD

Blood (2014) 124 (21): 620.

https://doi.org/10.1182/blood.V124.21.620.620

Published: 2014

Journal Articles

Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes

Diwakar R. Pattabiraman, Crystal McGirr, Konstantin Shakhbazov, Valerie Barbier, Keerthana Krishnan, Pamela Mukhopadhyay, Paula Hawthorne, Ann Trezise, Jianmin Ding, Sean M. Grimmond, Peter Papathanasiou, Warren S. Alexander, Andrew C. Perkins, Jean-Pierre Levesque, Ingrid G. Winkler, Thomas J. Gonda

Blood (2014) 123 (17): 2682–2690.

https://doi.org/10.1182/blood-2012-02-413187

Published: 2014

Includes: Supplemental data

Journal Articles

Hypoxia Inducible Factor (HIF)-2α Enhances Proliferation Of Malignant Hematopoietic Cells In The Hypoxic Malignant Bone Marrow

Catherine E Forristal, PhD, Falak Helwani, PhD, Sally Martin, Bianca Nowlan, Ingrid G Winkler, PhD, Andrew Zannettino, Jean-Pierre Levesque, PhD

Blood (2013) 122 (21): 2895.

https://doi.org/10.1182/blood.V122.21.2895.2895

Published: 2013

Journal Articles

Administration Of E-Selectin Antagonist GMI-1271 Improves Survival After High-Dose Chemotherapy By Alleviating Mucositis and Accelerating Neutrophil Recovery

Ingrid G Winkler, PhD, Valerie Barbier, Heather L Nutt, Sumaira Z Hasnain, PhD, Jean-Pierre Levesque, PhD, John L. Magnani, PhD, Michael A McGuckin, PhD

Blood (2013) 122 (21): 2266.

https://doi.org/10.1182/blood.V122.21.2266.2266

Published: 2013

Journal Articles

Mobilizing Doses Of G-CSF Stop Medullary Erythropoiesis By Depleting F4/80+ VCAM1+ ER-HR3+ CD169+ Erythroid-Island Macrophages

Rebecca Jacobsen, BSc, Allison R Pettit, PhD, Liza J Raggatt, PhD, Bianca Nowlan, Valerie Barbier, Catherine E Forristal, PhD, Ingrid G Winkler, PhD, Jean-Pierre Levesque, PhD

Blood (2013) 122 (21): 309.

https://doi.org/10.1182/blood.V122.21.309.309

Published: 2013

NARROW

Endothelial Protein C Receptor CD201 Enables Identification of Transplantable Mouse Hematopoietic Stem Cells in Inflammatory Conditions Unlike SCA1

Endotoxemia As Possible Cause of Inflammatory Bowel Diseases-Associated Anemia

Oncostatin M Is a Novel Niche Factor That Restrains Hematopoietic Stem Cell Mobilization in Response to G-CSF and CXCR4 Antagonist Plerixafor

Blocking Vascular Niche E-Selectin Dampens AML Stem Cell Regeneration/Survival Potential In Vivo By Inhibiting MAPK/ERK and PI3K/AKT Signalling Pathways

CD162 Is a Key E-Selectin Receptor Promoting Acute Myeloid Leukemia Chemo-Resistance in the Bone Marrow Niche

Prostaglandin I 2 in the Endosteal Bone Marrow Niche As a Novel Regulator of Hematopoietic Stem Cells

Vascular E-Selectin Acts As a Gatekeeper Inducing Commitment and Loss of Self-Renewal in HSC Transmigrating through the Marrow Vasculature

Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment

Vascular E-Selectin Mediates Chemo-Resistance in Acute Myeloid Leukemia Initiating Cells Via Canonical Receptors PSGL-1 (CD162) and Hcell (CD44) and AKT Signaling

Macrophage Involvement in the Response of Acute Myeloid Leukaemia to Chemotherapy

Suppression of Medullar Erythropoiesis in Response to Bacterial Lipopolysaccharides (LPS) Involves Two Distinct TLR4-Dependent Mechanisms with Contrasted Requirements for G-CSF Receptors

Vascular E-Selectin Protects Leukemia Cells from Chemotherapy By Directly Activating Pro-Survival NF-Kb Signalling - Therapeutic Blockade of E-Selectin Dampens NF-Kb Activation

Therapeutic Blockade of Macrophage Colony Stimulating Factor (CSF-1) Delays AML Progression in Mice In Vivo

Mobilization of CD8 + Central Memory T-Cells with Enhanced Reconstitution Potential in Mice By a Combination of G-CSF and GMI-1271-Mediated E-Selectin Blockade

Mobilisation of Reconstituting HSC Is Boosted By Synergy Between G-CSF and E-Selectin Antagonist GMI-1271.

Vascular Niche E-Selectin Protects Acute Myeloid Leukaemia Stem Cells from Chemotherapy

Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes

Hypoxia Inducible Factor (HIF)-2α Enhances Proliferation Of Malignant Hematopoietic Cells In The Hypoxic Malignant Bone Marrow

Administration Of E-Selectin Antagonist GMI-1271 Improves Survival After High-Dose Chemotherapy By Alleviating Mucositis and Accelerating Neutrophil Recovery

Mobilizing Doses Of G-CSF Stop Medullary Erythropoiesis By Depleting F4/80+ VCAM1+ ER-HR3+ CD169+ Erythroid-Island Macrophages

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American Society of Hematology

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ASH Publications

American Society of Hematology

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