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Bianca Nowlan
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Journal Articles

Prostaglandin I 2 in the Endosteal Bone Marrow Niche As a Novel Regulator of Hematopoietic Stem Cells

Joshua Tay, PhD, Jean-Pierre Levesque, PhD, Falak Helwani, PhD, Gareth Price, PhD, Bianca Nowlan, Masters, Valerie Barbier, Masters, Ingrid G Winkler, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2575.
https://doi.org/10.1182/blood-2018-99-115869
Published: 2018
Journal Articles

Suppression of Medullar Erythropoiesis in Response to Bacterial Lipopolysaccharides (LPS) Involves Two Distinct TLR4-Dependent Mechanisms with Contrasted Requirements for G-CSF Receptors

Kavita Bisht, PhD, Rebecca Jacobsen, BSc, Bianca Nowlan, Crystal McGirr, Marion Brunck, Thomas Keech, Ingrid G Winkler, PhD, Jean-Pierre Levesque, PhD
Journal: Blood
Blood (2016) 128 (22): 546.
https://doi.org/10.1182/blood.V128.22.546.546
Published: 2016
Journal Articles

Hypoxia Inducible Factor (HIF)-2α Enhances Proliferation Of Malignant Hematopoietic Cells In The Hypoxic Malignant Bone Marrow

Catherine E Forristal, PhD, Falak Helwani, PhD, Sally Martin, Bianca Nowlan, Ingrid G Winkler, PhD, Andrew Zannettino, Jean-Pierre Levesque, PhD
Journal: Blood
Blood (2013) 122 (21): 2895.
https://doi.org/10.1182/blood.V122.21.2895.2895
Published: 2013
Journal Articles

Mobilizing Doses Of G-CSF Stop Medullary Erythropoiesis By Depleting F4/80+ VCAM1+ ER-HR3+ CD169+ Erythroid-Island Macrophages

Rebecca Jacobsen, BSc, Allison R Pettit, PhD, Liza J Raggatt, PhD, Bianca Nowlan, Valerie Barbier, Catherine E Forristal, PhD, Ingrid G Winkler, PhD, Jean-Pierre Levesque, PhD
Journal: Blood
Blood (2013) 122 (21): 309.
https://doi.org/10.1182/blood.V122.21.309.309
Published: 2013
Journal Articles

Pharmacologic stabilization of HIF-1α increases hematopoietic stem cell quiescence in vivo and accelerates blood recovery after severe irradiation

Catherine E. Forristal, Ingrid G. Winkler, Bianca Nowlan, Valerie Barbier, Gail Walkinshaw, Jean-Pierre Levesque
Journal: Blood
Blood (2013) 121 (5): 759–769.
https://doi.org/10.1182/blood-2012-02-408419
Published: 2013
Includes: Supplemental data
Journal Articles

FG-4497, a Pharmacological Stabilizer of HIF-1α Protein, Synergistically Enhances Hematopoietic Stem Cells (HSC) Mobilization in Response to G-CSF and Plerixafor

Catherine E Forristal, PhD, Bianca Nowlan, Valerie Barbier, Ingrid G Winkler, PhD, Gail Walkinshaw, PhD, Jean-Pierre Levesque, PhD
Journal: Blood
Blood (2012) 120 (21): 216.
https://doi.org/10.1182/blood.V120.21.216.216
Published: 2012
Journal Articles

Oxygen-Independent Stabilization of the Oxygen-Labile Transcription Factor HIF-1α with Dimethyloxalyl Glycine or FG-4497 Increases Hematopoietic Stem Cell Quiescence In Vivo and Mobilization in Response to G-CSF

Catherine Forristal, PhD, Bianca Nowlan, Valerie Barbier, Domenica McCarthy, Gail Walkinshaw, PhD, Ingrid G Winkler, PhD, Jean-Pierre Levesque, PhD
Journal: Blood
Blood (2011) 118 (21): 2334.
https://doi.org/10.1182/blood.V118.21.2334.2334
Published: 2011
Journal Articles

Mobilizing Agents G-CSF, Cyclophosphamide or AMD3100 (Plerixafor) Have Distinct Effects on Osteoblasts, Hematopoietic Stem Cell Niches, and B-Lymphopoiesis,

Jean-Pierre Levesque, PhD, Linda J. Bendall, BSc, PhD, Allison R Pettit, PhD, Liza Raggatt, PhD, Rebecca Jacobsen, BSc, Valerie Barbier, Bianca Nowlan, Yi Shen, PhD, Natalie A Sims, PhD, Ingrid G Winkler, PhD
Journal: Blood
Blood (2011) 118 (21): 4005.
https://doi.org/10.1182/blood.V118.21.4005.4005
Published: 2011
Journal Articles

Impairment of Hematopoietic Stem Cell (HSC) Niche by G-CSF Is Associated with Rapid Mobilization of Serially Reconstituting HSC and Reduced Competitive Repopulation of Mobilized Bone Marrow

Jean-Pierre Levesque, PhD, Valerie Barbier, Bianca Nowlan, Domenica McCarhty, Ingrid G Winkler, PhD
Journal: Blood
Blood (2011) 118 (21): 1889.
https://doi.org/10.1182/blood.V118.21.1889.1889
Published: 2011
Journal Articles

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs

Ingrid G. Winkler, Natalie A. Sims, Allison R. Pettit, Valérie Barbier, Bianca Nowlan, Falak Helwani, Ingrid J. Poulton, Nico van Rooijen, Kylie A. Alexander, Liza J. Raggatt, Jean-Pierre Lévesque
Journal: Blood
Blood (2010) 116 (23): 4815–4828.
https://doi.org/10.1182/blood-2009-11-253534
Published: 2010
Includes: Supplemental data
Journal Articles

Absence or Blockage of E-Selectin-Mediated Cell Adhesion Delays Hematopoietic Stem Cell (HSC) Turn-Over and Enhances Chemoresistance.

Ingrid G Winkler, PhD, Valerie Barbier, Bianca Nowlan, Theodore Smith, John T Patton, John L. Magnani, Jean-Pierre Levesque, PhD
Journal: Blood
Blood (2009) 114 (22): 564.
https://doi.org/10.1182/blood.V114.22.564.564
Published: 2009
Journal Articles

Absence of E-Selectin at the Vascular Niche Delays Hematopoietic Stem Cell Turn-Over.

Ingrid G. Winkler, PhD, Bianca Nowlan, Valerie Barbier, Jean-Pierre Levesque, PhD
Journal: Blood
Blood (2007) 110 (11): 609.
https://doi.org/10.1182/blood.V110.11.609.609
Published: 2007