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Journal Articles

Glucocorticoids enhance the antileukemic activity of FLT3 inhibitors in FLT3-mutant acute myeloid leukemia

Melat T. Gebru, Jennifer M. Atkinson, Megan M. Young, Lijun Zhang, Zhenyuan Tang, Zhenqiu Liu, Pinyi Lu, Christopher M. Dower, Longgui Chen, Charyguly Annageldiyev, Arati Sharma, Yuka Imamura Kawasawa, Zhongming Zhao, Barbara A. Miller, David F. Claxton, Hong-Gang Wang
Journal: Blood
Blood (2020) 136 (9): 1067–1079.
https://doi.org/10.1182/blood.2019003124
Published: 2020
Includes: Supplemental data
Journal Articles

Therapeutic Efficacy of Mcl-1 Antagonism in Large Granular Lymphocyte Leukemia

Francis R LeBlanc, PhD, Jun Yang, MD, John H Heller, B.S., Shubha Dighe, M.S., Alejandro A. Gru, MD, Marya Dunlap-Brown, M.S., Hong-Gang Wang, PhD, David J Feith, PhD, Thomas P Loughran, Jr., MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1217.
https://doi.org/10.1182/blood.V130.Suppl_1.1217.1217
Published: 2017
Journal Articles

FTY720 (Fingolimod) Targets the Sphingolipid Pathway and Induces Autophagy-Related Apoptosis in Human Natural Killer Large Granular Lymphocyte Leukemia

Francis Roland LeBlanc, B.S., Hong-Gang Wang, MD PhD, David J. Feith, PhD, Thomas P. Loughran, Jr., MD
Journal: Blood
Blood (2015) 126 (23): 1288.
https://doi.org/10.1182/blood.V126.23.1288.1288
Published: 2015
Journal Articles

Selective Deletion of ATG5 in Bone Marrow Leptin-Receptor-Expressing Perivascular Stromal Cells Causes Leukopenia

Shabnam Arsiwala, MD, Wei Ding, MDPhD, Hong-Gang Wang, PhD
Journal: Blood
Blood (2015) 126 (23): 2395.
https://doi.org/10.1182/blood.V126.23.2395.2395
Published: 2015
Journal Articles

Combinatorial Anti-Leukemic Activity Of Liposomal Ceramide and Inhibitors Of Autophagy

Brian Barth, Ph.D., Nicole Keasey, PhD, Lindsey Fisher, Bsc, Megan Young, Bsc, Stephan Stern, PhD, Thomas P. Loughran, Jr., MD, Mark Kester, PhD, Hong-Gang Wang, PhD, David F. Claxton, MD
Journal: Blood
Blood (2013) 122 (21): 2694.
https://doi.org/10.1182/blood.V122.21.2694.2694
Published: 2013
Journal Articles

Bif-1 haploinsufficiency promotes chromosomal instability and accelerates Myc -driven lymphomagenesis via suppression of mitophagy

Yoshinori Takahashi, Tsukasa Hori, Timothy K. Cooper, Jason Liao, Neelam Desai, Jacob M. Serfass, Megan M. Young, Sungman Park, Yayoi Izu, Hong-Gang Wang
Journal: Blood
Blood (2013) 121 (9): 1622–1632.
https://doi.org/10.1182/blood-2012-10-459826
Published: 2013
Includes: Supplemental data
Journal Articles

Therapeutic efficacy of FTY720 in a rat model of NK-cell leukemia

Aijun Liao, Kathleen Broeg, Todd Fox, Su-Fern Tan, Rebecca Watters, Mithun Vinod Shah, Lucy Q. Zhang, Yongping Li, Lindsay Ryland, Jun Yang, Cesar Aliaga, Alden Dewey, Andrew Rogers, Kelly Loughran, Leah Hirsch, Nancy Ruth Jarbadan, Kendall Thomas Baab, Jason Liao, Hong-Gang Wang, Mark Kester, Dhimant Desai, Shantu Amin, Thomas P. Loughran, Jr, Xin Liu
Journal: Blood
Blood (2011) 118 (10): 2793–2800.
https://doi.org/10.1182/blood-2011-01-331447
Published: 2011
Includes: Supplemental data
Journal Articles

Therapeutic Efficacy of FTY720 In a Rat Model of LGL Leukemia

Xin Liu, Aijun Liao, Hong-Gang Wang, Dhimant Desai, Shantu Amin, Thomas P. Loughran, Jr., MD
Journal: Blood
Blood (2010) 116 (21): 776.
https://doi.org/10.1182/blood.V116.21.776.776
Published: 2010
Journal Articles

Regulation of 17-AAG—induced apoptosis: role of Bcl-2, Bcl-x L , and Bax downstream of 17-AAG—mediated down-regulation of Akt, Raf-1, and Src kinases

Ramadevi Nimmanapalli, Erica O'Bryan, Deborah Kuhn, Hirohito Yamaguchi, Hong-Gang Wang, Kapil N. Bhalla
Journal: Blood
Blood (2003) 102 (1): 269–275.
https://doi.org/10.1182/blood-2002-12-3718
Published: 2003
Journal Articles

Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative–(BMS 247550) and Apo-2L/TRAIL–induced apoptosis

Fei Guo, Ramadevi Nimmanapalli, Shanthi Paranawithana, Sylvie Wittman, David Griffin, Purva Bali, Erica O'Bryan, Carlos Fumero, Hong Gang Wang, Kapil Bhalla
Journal: Blood
Blood (2002) 99 (9): 3419–3426.
https://doi.org/10.1182/blood.V99.9.3419
Published: 2002
Journal Articles

Expression of Apoptosis-Regulating Proteins in Chronic Lymphocytic Leukemia: Correlations With In Vitro and In Vivo Chemoresponses

Shinichi Kitada, Janet Andersen, Sophie Akar, Juan M. Zapata, Shinichi Takayama, Stanislaw Krajewski, Hong-Gang Wang, Xin Zhang, Florencia Bullrich, Carlo M. Croce, Kanti Rai, John Hines, John C. Reed
Journal: Blood
Blood (1998) 91 (9): 3379–3389.
https://doi.org/10.1182/blood.V91.9.3379
Published: 1998
Journal Articles

Immunohistochemical Analysis of Interleukin-1β–Converting Enzyme/Ced-3 Family Protease, CPP32/Yama/Caspase-3, in Hodgkin's Disease

Mukesh Chhanabhai, Stanislaw Krajewski, Maryla Krajewska, Hong-Gang Wang, John C. Reed, Randy D. Gascoyne
Journal: Blood
Blood (1997) 90 (6): 2451–2455.
https://doi.org/10.1182/blood.V90.6.2451
Published: 1997
Journal Articles

Immunolocalization of the ICE/Ced-3–Family Protease, CPP32 (Caspase-3), in Non-Hodgkin's Lymphomas, Chronic Lymphocytic Leukemias, and Reactive Lymph Nodes

Stanislaw Krajewski, Randy D. Gascoyne, Juan M. Zapata, Maryla Krajewska, Shinichi Kitada, Mukesh Chhanabhai, Douglas Horsman, Ken Berean, Lawrence D. Piro, Isabelle Fugier-Vivier, Yong-Jun Liu, Hong-Gang Wang, John C. Reed
Journal: Blood
Blood (1997) 89 (10): 3817–3825.
https://doi.org/10.1182/blood.V89.10.3817
Published: 1997