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Journal Articles

CAR-T Cell Subsets and Immune Repertoire Are Associated with Immune-Related Adverse Events and Efficacy after CD19 CAR T-Cell Therapy in B Cell Lymphoma

David M Foureau, Fei Guo, Erik Broemsen, Tahj Jones, Anna Ivanina-Foureau, Ryan Jacobs, Bei Hu, Tamara K Moyo, Yifan Pang, Steven I. Park, Lawrence J. Druhan, Ariel Bell, Nilanjan Ghosh

Blood (2024) 144 (Supplement 1): 2053.

https://doi.org/10.1182/blood-2024-205720

Published: 2024

Journal Articles

Myeloid Derived Suppressor Cell Kinetics in Peripheral Blood Correlate with Efficacy and Toxicity of CAR T Cell Therapy in Relapsed or Refractory B Cell Lymphoma

David M Foureau, Hamid Ehsan, Fei Guo, Tahj Jones, Ryan W Jacobs, Bei Hu, Tamara K. Moyo, Yifan Pang, Steven I. Park, Lawrence J. Druhan, Ariel Bell, Nilanjan Ghosh

Blood (2023) 142 (Supplement 1): 1640.

https://doi.org/10.1182/blood-2023-187085

Published: 2023

Journal Articles

Central Memory T-Cell Differentiation Correlates with Depth of Response in Relapsed/Refractory Multiple Myeloma Patients Receiving Elotuzumab in Combination with Carfilzomib, Lenalidomide and Dexamethasone (Elo-KRd)

David M Foureau, Manisha Bhutani, Fei Guo, Kateryna Fesenkova, Shebli Atrash, Reed Friend, Barry Paul, Myra M Robinson, James T Symanowski, Lawrence J Druhan, Mauricio Pineda-Roman, Peter M. Voorhees, Saad Z. Usmani

Blood (2021) 138 (Supplement 1): 1585.

https://doi.org/10.1182/blood-2021-152505

Published: 2021

Journal Articles

Molecular Characterization By Immune Profiling of Paired Blood and Bone Marrow in Multiple Myeloma and Its Precursor States

Manisha Bhutani, MD, David M. Foureau, PhD, Nury M Steuerwald, PhD, Sally Trufan, Fei Guo, PhD, Katherine Rigby, Elise Tjaden, Alicia Hamilton, Marina Leonidas, Aarin Berlin, Laura Johnson, Jordan Williams, Shebli Atrash, Ami P Ndiaye, NP, James Symanowski, PhD, Peter M. Voorhees, MD, Saad Z. Usmani, MD

Blood (2018) 132 (Supplement 1): 4461.

https://doi.org/10.1182/blood-2018-99-118281

Published: 2018

Journal Articles

Ex Vivo Assessment of Tnb-383B, a Bcma-Bispecific Antibody, Against Primary Tumor and Endogenous T Cells from Relapsing Multiple Myeloma Patients

David M. Foureau, PhD, Manisha Bhutani, MD, Myra Robinson, MS, Fei Guo, PhD, Duy Pham, Shelley Force Aldred, Ben Buelow, MD PhD, Katherine Rigby, Elise Tjaden, Marina Leonidas, Shebli Atrash, Ami P Ndiaye, NP, James Symanowski, PhD, Peter M. Voorhees, MD, Saad Z. Usmani, MD

Blood (2018) 132 (Supplement 1): 1940.

https://doi.org/10.1182/blood-2018-99-118881

Published: 2018

Journal Articles

Effect of Immunomodulatory Drugs (IMiDs) on Immune Effectors after Autologous Stem Cell Transplantation (ASCT) in Multiple Myeloma

David M Foureau, PhD, Manisha Bhutani, MD, Qing Zhang, PhD, Myra M Robinson, MSPH, Adina Wynn, Nury M Steuerwald, PhD, Lawrence J Druhan, PhD, Fei Guo, PhD, Katherine Rigby, Mitchell Turner, Reed Friend, MD, Shebli Atrash, Chelsea Sprouse, Ami Ndiaye, James T Symanowski, PhD, Belinda Rene Avalos, MD, Edward A Copelan, MD, Peter M. Voorhees, MD, Saad Z Usmani, MD

Blood (2017) 130 (Supplement 1): 1817.

https://doi.org/10.1182/blood.V130.Suppl_1.1817.1817

Published: 2017

Journal Articles

Correlation of Myeloid Derived Suppressor Cells and Response to Standard Chemoimmunotherapy in Diffuse Large B Cell Lymphoma

David M. Foureau, PhD, Qing Zhang, PhD, Lawrence J Druhan, PhD, Ryan Jacobs, MD, Fei Guo, PhD, Steven I Park, MD, Danyu Sun, MD PhD, Edward A Copelan, MD, Belinda Rene Avalos, MD, Nilanjan Ghosh, MD PhD

Blood (2017) 130 (Supplement 1): 4023.

https://doi.org/10.1182/blood.V130.Suppl_1.4023.4023

Published: 2017

Journal Articles

Aberrant Trafficking and Signal Propagation By the T618I CSF3R Mutant in Patients with Chronic Neutrophilic Leukemia

Lawrence J Druhan, PhD, Andrea Price, Amanda Lance, Alicia Hamilton, Judy Parsons, MT, Fei Guo, PhD, David M Foureau, PhD, Nury M Steuerwald, PhD, Belinda Rene Avalos, MD

Blood (2017) 130 (Supplement 1): 2941.

https://doi.org/10.1182/blood.V130.Suppl_1.2941.2941

Published: 2017

Journal Articles

Peripheral Cellular Immunome Reveals Heterogeneity Spanning Myeloma Spectrum Diseases

Manisha Bhutani, MD, David M Foureau, PhD, Qing Zhang, PhD, Myra M Robinson, MSPH, Adina Wynn, Nury M Steuerwald, PhD, Lawrence J Druhan, PhD, Fei Guo, PhD, Katherine Rigby, Mitchell Turner, Reed Friend, MD, Shebli Atrash, Ami Ndiaye, Chelsea Sprouse, James T Symanowski, PhD, Belinda Rene Avalos, MD, Edward A Copelan, MD, Peter M. Voorhees, MD, Saad Z Usmani, MD

Blood (2017) 130 (Supplement 1): 3054.

https://doi.org/10.1182/blood.V130.Suppl_1.3054.3054

Published: 2017

Journal Articles

NF-κb / STAT3 Signaling Pathway Collaboration in Diffuse Large B-Cell Lymphoma (DLBCL) Cell-of-Origin (COO) Subtypes: Resolution of Myeloid Subversion By Standard Induction Chemotherapy

David Foureau, PhD, Qing Zhang, PhD, Lawrence J. Druhan, PhD, Nury M. Steuerwald, PhD, Fei Guo, Elizabeth Jandrisevits, Belinda R. Avalos, MD, Danyu Sun, MD PhD, Ryan Jacobs, MD, Nilanjan Ghosh, MD PhD

Blood (2016) 128 (22): 4133.

https://doi.org/10.1182/blood.V128.22.4133.4133

Published: 2016

Journal Articles

Peripheral Immune Profile and Minimal Residual Disease (MRD) Burden Following Autologous Stem Cell Transplantation (ASCT) in Multiple Myeloma (MM)

David Foureau, PhD, Qing Zhang, PhD, Tammy D Cogdill, NP, Adina S Wynn, Nury M. Steuerwald, PhD, Lawrence J. Druhan, PhD, Fei Guo, Katherine Rigby, Kyle L Madden, BS, James T Symanowski, PhD, Belinda R. Avalos, MD, Edward A. Copelan, MD FACP, Saad Z Usmani, MD FACP, Manisha Bhutani, MD

Blood (2016) 128 (22): 378.

https://doi.org/10.1182/blood.V128.22.378.378

Published: 2016

Journal Articles

Increased Levels of the Heat Shock Protein (hsp) 70 Contribute as a Pro-Survival and Pro-Growth Mechanism in the Transformation of Bone Marrow Progenitor Cells.

Sandhya Boyapalle, PhD, Kathy Rocha, BS, Fei Guo, PhD, Purva Bali, MS, Maria Balasis, BS, Warren Fiskus, PhD, Sandhya Kumaraswamy, PhD, Michael Pranpat, MS, Kapil Bhalla, MD

Blood (2005) 106 (11): 1374.

https://doi.org/10.1182/blood.V106.11.1374.1374

Published: 2005

Journal Articles

Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3

Prince George, Purva Bali, Srinivas Annavarapu, Anna Scuto, Warren Fiskus, Fei Guo, Celia Sigua, Gautam Sondarva, Lynn Moscinski, Peter Atadja, Kapil Bhalla

Blood (2005) 105 (4): 1768–1776.

https://doi.org/10.1182/blood-2004-09-3413

Published: 2005

Journal Articles

Mechanistic role of heat shock protein 70 in Bcr-Abl–mediated resistance to apoptosis in human acute leukemia cells

Fei Guo, Celia Sigua, Purva Bali, Prince George, Warren Fiskus, Anna Scuto, Srinivas Annavarapu, Abdelmoughite Mouttaki, Gautam Sondarva, Sheng Wei, Jie Wu, Julie Djeu, Kapil Bhalla

Blood (2005) 105 (3): 1246–1255.

https://doi.org/10.1182/blood-2004-05-2041

Published: 2005

Journal Articles

Molecular Characterization of Human AML Cells with Resistance to Growth-Inhibitory and Apoptotic Effects of Hydroxamic Acid Analogue Histone Deacetylase Inhibitors.

Fei Guo, Ph.D., Celia Sigua, M.S., Purva Bali, M.S., Warren Fiskus, Ph.D., Gautam Sondarva, Ph.D., Srinivas Annavarapu, M.S., Abdelmoughite Mouttaki, B.S., Peter Atadja, Ph.D., Kapil N. Bhalla, M.D.

Blood (2004) 104 (11): 1171.

https://doi.org/10.1182/blood.V104.11.1171.1171

Published: 2004

Journal Articles

Synergistic Cytotoxic Effects of a Combination of a Novel Tyrosine Kinase Inhibitor AMN107 and Histone Deacetylase Inhibitor LBH589 Against Bcr-Abl Expressing Human Leukemia Cells.

Anna Scuto, Ph.D., Srinivas Annavarapu, M.S., Purva Bali, M.S., Molly McCullers, Warren Fiskus, Ph.D., Abdelmoughite Mouttaki, B.S., Fei Guo, Ph.D., Celia Sigua, M.S., Gautam Sondarva, Ph.D., Peter Atadja, Ph.D., Paul Manley, Ph.D., Kapil N. Bhalla, M.D.

Blood (2004) 104 (11): 1977.

https://doi.org/10.1182/blood.V104.11.1977.1977

Published: 2004

Journal Articles

Molecular Characterization of Human CML Cells with Resistance to the Heat Shock Protein (hsp) 90 Inhibitor 17-Allylamino-Demethoxy Geldanamycin (17-AAG).

Purva Bali, M.S., Warren Fiskus, Ph.D., Fei Guo, Ph.D., Srinivas Annavarapu, M.S., Celia Sigua, M.S., Gautam Sondarva, Ph.D., Abdelmoughite Mouttaki, B.S., Peter Atadja, Ph.D., Paul Manley, Ph.D., Kapil N. Bhalla, M.D.

Blood (2004) 104 (11): 1980.

https://doi.org/10.1182/blood.V104.11.1980.1980

Published: 2004

Journal Articles

Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative–(BMS 247550) and Apo-2L/TRAIL–induced apoptosis

Fei Guo, Ramadevi Nimmanapalli, Shanthi Paranawithana, Sylvie Wittman, David Griffin, Purva Bali, Erica O'Bryan, Carlos Fumero, Hong Gang Wang, Kapil Bhalla

Blood (2002) 99 (9): 3419–3426.

https://doi.org/10.1182/blood.V99.9.3419

Published: 2002

NARROW

CAR-T Cell Subsets and Immune Repertoire Are Associated with Immune-Related Adverse Events and Efficacy after CD19 CAR T-Cell Therapy in B Cell Lymphoma

Myeloid Derived Suppressor Cell Kinetics in Peripheral Blood Correlate with Efficacy and Toxicity of CAR T Cell Therapy in Relapsed or Refractory B Cell Lymphoma

Central Memory T-Cell Differentiation Correlates with Depth of Response in Relapsed/Refractory Multiple Myeloma Patients Receiving Elotuzumab in Combination with Carfilzomib, Lenalidomide and Dexamethasone (Elo-KRd)

Molecular Characterization By Immune Profiling of Paired Blood and Bone Marrow in Multiple Myeloma and Its Precursor States

Ex Vivo Assessment of Tnb-383B, a Bcma-Bispecific Antibody, Against Primary Tumor and Endogenous T Cells from Relapsing Multiple Myeloma Patients

Effect of Immunomodulatory Drugs (IMiDs) on Immune Effectors after Autologous Stem Cell Transplantation (ASCT) in Multiple Myeloma

Correlation of Myeloid Derived Suppressor Cells and Response to Standard Chemoimmunotherapy in Diffuse Large B Cell Lymphoma

Aberrant Trafficking and Signal Propagation By the T618I CSF3R Mutant in Patients with Chronic Neutrophilic Leukemia

Peripheral Cellular Immunome Reveals Heterogeneity Spanning Myeloma Spectrum Diseases

NF-κb / STAT3 Signaling Pathway Collaboration in Diffuse Large B-Cell Lymphoma (DLBCL) Cell-of-Origin (COO) Subtypes: Resolution of Myeloid Subversion By Standard Induction Chemotherapy

Peripheral Immune Profile and Minimal Residual Disease (MRD) Burden Following Autologous Stem Cell Transplantation (ASCT) in Multiple Myeloma (MM)

Increased Levels of the Heat Shock Protein (hsp) 70 Contribute as a Pro-Survival and Pro-Growth Mechanism in the Transformation of Bone Marrow Progenitor Cells.

Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3

Mechanistic role of heat shock protein 70 in Bcr-Abl–mediated resistance to apoptosis in human acute leukemia cells

Molecular Characterization of Human AML Cells with Resistance to Growth-Inhibitory and Apoptotic Effects of Hydroxamic Acid Analogue Histone Deacetylase Inhibitors.

Synergistic Cytotoxic Effects of a Combination of a Novel Tyrosine Kinase Inhibitor AMN107 and Histone Deacetylase Inhibitor LBH589 Against Bcr-Abl Expressing Human Leukemia Cells.

Molecular Characterization of Human CML Cells with Resistance to the Heat Shock Protein (hsp) 90 Inhibitor 17-Allylamino-Demethoxy Geldanamycin (17-AAG).

Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative–(BMS 247550) and Apo-2L/TRAIL–induced apoptosis

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American Society of Hematology

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ASH Publications

American Society of Hematology

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