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Holly K. Koblish
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Journal Articles

Characterization of INCB00928, a Potent and Selective ALK2 Inhibitor for the Treatment of Anemia

Yaoyu Chen, Matthew C. Stubbs, PhD, Michelle Pusey, Xiaoming Wen, Robert J. Collins, Kanishk Kapilashrami, Mark Rupar, Pramod Thekkat, Luping Lin, PhD, Kevin Bowman, Yan-ou Yang, Sharon Diamond, Swamy Yeleswaram, PhD, Sunkyu Kim, Holly K. Koblish, PhD, Yingnan Chen, Susan Wee, PhD BS
Journal: Blood
Blood (2020) 136 (Supplement 1): 52.
https://doi.org/10.1182/blood-2020-136138
Published: 2020
Journal Articles

Bromodomain and Extra Terminal Domain (BET) Inhibitors Sensitize Chronic Myelomonocytic Leukemia (CMML) to PIM Inhibition Via Downregulation of Mir-33a

Christopher Letson, BS, Alexis Vedder, BS, Ariel Quintana, PhD, Phillip Liu, PhD, Brett Reid, Maria E Balasis, Hannah Newman, BS, Traci Kruer, PhD, Luciana L Almada, PhD, Guolin Zhang, PhD, Martin Fernandez-Zapico, MD, Mrinal M Patnaik, MDMBBS, Jeffrey E. Lancet, MD, Rami S. Komrokji, MD, P.K. Epling-Burnette, PharmD, PhD, Alan F. List, MD, Eric B. Haura, MD, Gary W. Reuther, Thomas A. Sellers, PhD, Holly K. Koblish, PhD, Eric Padron, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4220.
https://doi.org/10.1182/blood-2019-128165
Published: 2019
Journal Articles

Cytokine Activation of JAK Kinases Rescues FLT3-Mutant AML from FLT3 Inhibition and Requires PIM Kinases

Pamela J. Sung, MD PhD, Holly K. Koblish, PhD, Alexander E. Perl, MD, Martin Carroll, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1250.
https://doi.org/10.1182/blood.V130.Suppl_1.1250.1250
Published: 2017
Journal Articles

The Pan-PIM Inhibitor INCB053914 Displays Potent Synergy at Low Doses in Combination with Ruxolitinib in Pre-Clinical Models of MPNs

Lucia Mazzacurati, Que T. Lambert, Robert J. Collins, Holly K. Koblish, PhD, Bruce Ruggeri, Matthew C. Stubbs, Gary W. Reuther, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1661.
https://doi.org/10.1182/blood.V130.Suppl_1.1661.1661
Published: 2017
Journal Articles

Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity

Xiangdong Liu, Niu Shin, Holly K. Koblish, Gengjie Yang, Qian Wang, Kathy Wang, Lynn Leffet, Michael J. Hansbury, Beth Thomas, Mark Rupar, Paul Waeltz, Kevin J. Bowman, Padmaja Polam, Richard B. Sparks, Eddy W. Yue, Yanlong Li, Richard Wynn, Jordan S. Fridman, Timothy C. Burn, Andrew P. Combs, Robert C. Newton, Peggy A. Scherle
Journal: Blood
Blood (2010) 115 (17): 3520–3530.
https://doi.org/10.1182/blood-2009-09-246124
Published: 2010