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Herman S Overkleeft
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Journal Articles

Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules

Genevieve Marcoux, Audrée Laroche, Stephan Hasse, Marie Bellio, Maroua Mbarik, Marie Tamagne, Isabelle Allaeys, Anne Zufferey, Tania Lévesque, Johan Rebetz, Annie Karakeussian-Rimbaud, Julie Turgeon, Sylvain G. Bourgoin, Hind Hamzeh-Cognasse, Fabrice Cognasse, Rick Kapur, John W. Semple, Marie-Josée Hébert, France Pirenne, Herman S. Overkleeft, Bogdan I. Florea, Mélanie Dieude, Benoît Vingert, Eric Boilard
Journal: Blood
Blood (2021) 138 (25): 2607–2620.
https://doi.org/10.1182/blood.2020009957
Published: 2021
Includes: Supplemental data
Journal Articles

High-Dose Carfilzomib Recaptures Response in Relapsed/Refractory Multiple Myeloma Resistant to Low-Dose Carfilzomib By Co-Inhibiting β2 Subunit of Proteasome Complex: The First in Human Evidence

Xiang Zhou, Andrej Besse, Jessica Peter, Max Mendez Lopez, Larissa Haertle, Umair Munawar, Seungbin Han, Elmer Maurits, Herman S. Overkleeft, Hermann Einsele, Christoph Driessen, Martin Kortuem, Lenka Besse, Leo Rasche
Journal: Blood
Blood (2021) 138 (Supplement 1): 818.
https://doi.org/10.1182/blood-2021-147170
Published: 2021
Journal Articles

All-Trans-Retinoic Acid Prevents Carfilzomib-Induced Cardiotoxicity By Decreasing Activation of the Renin-Angiotensin System

Max A Mendez, Andrej Besse, Bogdan I. Florea, Christian Zuppinger, Herman S. Overkleeft, Lenka Besse, Christoph Driessen, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 19–20.
https://doi.org/10.1182/blood-2020-139277
Published: 2020
Journal Articles

Nelfinavir Overcomes Proteasome Inhibitor Resistance in Multiple Myeloma By Modulating Membrane Lipid Bilayer Composition and Fluidity

Andrej Besse, Lenka Besse, Sara C. Stolze, Amin Sobh, PhD, Esther A. Zaal, Alwin J van der Ham, Mario Ruiz, Santosh Phuyal, Lorina Büchler, Marc Sathianathan, Bogdan I. Florea, Jan Borén, Marcus Ståhlman, Alex Loguinov, Bart Everts, Celia R. Berkers, Marc Pilon, Hesso Farhan, Chris D. Vulpe, Herman S. Overkleeft, Christoph Driessen, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11.
https://doi.org/10.1182/blood-2020-136253
Published: 2020
Journal Articles

Nelfinavir Blocks Export of Newly Synthesized Protein from the ER and Interacts with ER-Resident and Mitochondrial Proteins in an Activity-Dependent Fashion

Andrej Besse, Lenka Besse, Sara C. Stolze, Marianne Kraus, Juergen Bader, Herman S Overkleeft, Christoph Driessen, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3074.
https://doi.org/10.1182/blood.V130.Suppl_1.3074.3074
Published: 2017
Journal Articles

Defining the Most Effective Proteasome Inhibition in Multiple Myeloma: Head-to-Head Comparison of Currently Available Proteasome Inhibitors

Andrej Besse, Lenka Besse, Marianne Kraus, Juergen Bader, Gerjan de Bruin, Herman S Overkleeft, Christoph Driessen, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5388.
https://doi.org/10.1182/blood.V130.Suppl_1.5388.5388
Published: 2017
Journal Articles

Proteasome Inhibitor-Adapted Myeloma Cells That Lack Proteasome Gene Mutations Resist Highly Efficient Proteasome Inhibition and Show Proteomic Alterations That Suggest Complex Metabolic Changes

Lenka Besse, PhD, Guillem Soriano, Nan Li, Andrej Besse, Marianne Kraus, Juergen Bader, Tobias Christian Silzle, MD, Nico Meeuwenoord, Hans den Dulk, Herman S Overkleeft, Bogdan Florea, Christoph Driessen, MD
Journal: Blood
Blood (2015) 126 (23): 1278.
https://doi.org/10.1182/blood.V126.23.1278.1278
Published: 2015